Generic antibiotics for the treatment of sinusitis. Review of antibiotics for sinusitis: top best. What antibiotics will help

Treatment of sinusitis in patients of the adult age group involves the use of a large number and varieties of drugs that are designed to suppress the activity of bacterial microflora and relieve the inflammatory process inside the paranasal sinus. One of such effective means in the fight against pathogens are antibiotics for sinusitis. They are introduced into the patient's body in the form intramuscular injections and tablets. What type of medication to use in a particular clinical case is determined by the attending otolaryngologist. More severe forms diseases are treated with antibacterial agents in the form of injections, and non-complicated types of the disease can be cured with the help of drugs in tablets or syrups.

There is a large selection of drugs, the intended purpose of which is the destruction of microbes that, together with the flow of air or blood, entered the cavity of the paranasal sinus and caused chronic or acute inflammation of the mucous membrane. From the whole variety of drugs in the pharmacological industry, we single out the following most effective antibacterial agents.

Amoxiclav

Combined antibiotic, which belongs to the group of semi-synthetic penicillins. According to the data World Organization health care, is listed as an essential medicine that plays a key role in the survival of mankind. In the treatment of sinusitis, it is used to combat Staphylococcus aureus and its varieties, Pseudomonas aeruginosa, streptococcal infection and other microorganisms, the infection of which provoked the development of a purulent-inflammatory process with all the ensuing consequences. The cost of one package of Amoxiclav in a pharmacy is 280-300 rubles.

Avamys

The strongest anti-inflammatory agent, which is produced by the manufacturer in the form of drops. They are intended for the treatment of sinusitis of any form and complexity of the course. It has a strong anti-edematous effect, inhibits the growth of bacterial microflora, stabilizes hydration of the mucous membrane overdried with disease. It is enough to apply 1-2 drops of Avamys daily into the nasal cavity for 10 days to completely get rid of the signs of the disease. The price of 1 bottle of the drug is 320 rubles. It is released in pharmacies without a special prescription from a doctor.

Azithromycin

As part of this antibacterial drug contains an active substance that has a similar name with the brand of the drug - "azithromycin". A medicine for sinusitis is produced in capsules closed with a gelatin shell. Average duration treatment is from 7 to 14 days and directly depends on the form of the disease that affected the epithelial tissues of the nasopharynx, as well as the severity of its course. The patient every day takes 1-2 capsules of the drug 3-4 times a day. Tablets can be used as an independent remedy for pathogenic bacteria or included by an otolaryngologist as part of a comprehensive therapeutic course. The cost is 70 rubles for a package consisting of 2 capsules.

Amoxicillin

Broad-spectrum penicillin, which is indicated for use in the treatment of ENT diseases. Sinusitis in this case is no exception. The antibiotic itself is available in the form of tablets. Excellent for the treatment of complicated forms of the disease, when inflammation spreads to the lower Airways.

In medical practice, Amoxicillin is considered a universal antibiotic that is effective against most known to science microbes that cause pathological processes in maxillary sinuses Oh.

The price of this medicinal product is in the range of 100-120 rubles per pack.

Ampicillin

Semi-synthetic penicillin, which, compared with its counterparts, has an extremely wide spectrum of action. Already 2 hours after taking the capsule of the drug in the blood, the level of antiseptic components reaches a peak. The principle of action of this antibiotic is that it inhibits the synthesis of intercellular substance in the walls of bacteria, which makes it impossible for further division of microbes. As a result, cell activity increases dramatically. immune system, which makes it much easier to fight pathogenic infection. The cost of tablets will cost the buyer 45-50 rubles per pack.

ASD

Dorogov's antiseptic stimulator. The strongest antibacterial agent, which is designed to quickly relieve the inflammatory process in the paranasal sinuses and stabilize the normal functioning of the nasopharynx. In addition, the suspension stimulates the regenerative properties of the body, restoring damaged areas of the mucosa, heals ulcers and erosion. The ASD contains natural antibiotics obtained as a result of thermal processing of bone meal, as well as plants with healing properties. The full composition of the drug is kept in strict confidence. During the treatment of sinusitis, it is taken orally as a mixture and is introduced into the nasal cavity in the form of antimicrobial drops.

Augmentin

Antibacterial powder for oral suspension. To get an excellent remedy for inflammation of the paranasal sinus cavity, it is enough to take 1 teaspoon of Augmentin white powder and dissolve it in 2 tsp. saline. After that, the patient takes the drug orally 3 times a day, 4 drops 15 before meals. They can also be instilled into the nose, like regular anti-inflammatory drops. Terms of treatment 5-7 days. The antibiotic is considered quite potent, so the duration of its use is limited. This is necessary so that there is no addiction to the immune system and directly to the pathogenic microflora itself. The price of one vial of powder for the preparation of a suspension is 230 rubles.

ACC

The composition of this medication includes Acetylcysteine, which is prescribed for sinusitis, as an antibacterial and mucolytic agent with a wide spectrum of action. The main purpose of the drug is to liquefy too viscous and thick mucus that has accumulated in the maxillary sinuses and cannot be evacuated on its own in a natural way. It is indicated for use in patients who are at risk of accumulation of purulent exudate. The price of one sachet of ACC is 260 rubles.

Bioparox

The composition of this antibiotic is a substance - fusafungin, which has antiseptic and anti-inflammatory properties. It is used exclusively locally, since the form of release of the drug is a spray. Effective against inflammation of the paranasal sinus, which is caused by such pathogenic microorganisms as strain A streptococci, staphylococci, pneumococci. Also, Bioparox antibacterial drops are effective against fungal infections of the Candida albicans and Mycoplasma group. The cost of the spray is from 150 to 300 rubles per bottle. The duration of therapy is from 5 to 10 days.

Biseptol

White tablets, which have a pronounced antibacterial effect. They contain sulfamethoxazole trimethoprim in their composition, which ensures the destruction of most gram-positive and gram-negative microorganisms. The advantage of using Biseptol in the treatment of sinusitis is that it helps to get rid of bacteria that are resistant to sulfanilamide drugs. The price of one package of this tablet preparation is 190-210 rubles. Released without a prescription.

Bronchomunal

The drug stimulates alveolar macrophages, which are responsible for the secretory activity of cytokines. This is a substance produced by the body in order to protect the mucosa from infection. Also, due to this effect, the mucus in the cavity of the maxillary sinus does not become so thick, which is an excellent prevention of the formation of exudate. Produced in the form of capsules, coated with a protective shell. The cost of the drug is at the level of 250 rubles per pack.

Wilprafen

vitaon

Natural natural antibacterial spectrum of action. It has a liquid oily consistency, since most of the constituent components of the drug are essential oils medicinal plants. During the treatment of sinusitis, Vitaon is used as antimicrobial, regenerating and anti-inflammatory drops.

It is enough just to apply 1-2 drops in each nostril in the morning and in the evening, so that already on the 4th day from the start of their use, the signs of the inflamed maxillary sinus gradually disappear.

Gelomirtol

Combined drug that belongs to the group of triglycerides. It has an antibacterial and mucolytic effect. It is indicated for use in the treatment of inflammatory diseases of the upper and lower respiratory tract. In the case of sinusitis, Gelomirtol allows you to make too thick and viscous mucus at the mouth of the sinuses, more liquid than it prevents the surgical puncture of the sinus. The drug itself has the appearance of a yellow gelatin capsule. It is taken 2-3 times a day for 10 days. The cost of one package will cost the buyer 260 rubles.

Gentamicin

An antibiotic from the group of aminoglycosides. It was originally created and also used in practical medicine as antimicrobial eye drops. In modern otolaryngology, the drug is also used to complex therapy sinusitis. Suppresses the activity of most gram-positive microorganisms, disrupting the synthesis of their protein compounds. It is prescribed exclusively by the attending otolaryngologist. Also, the drug prevents the development of complications of the inflammatory pathology of the sinuses, extending to the mucous membrane of the organ of vision. At the same time, the drops are quite affordable in material terms, since their cost is only 60 rubles per bottle.

Hydrocortisone

Antimicrobial corticosteroid ointment. It is actively used for focal control of inflammatory processes on the epithelial tissues of the body and the mucous membrane. If the patient has sinusitis, with the help of this drug the walls of the nasal canals and the surface of the face in the region of the wings of the nose are lubricated. The pharmaceutical purpose of the drug is to relieve edema, suppress pathogenic microflora and restore breathing through the nasopharynx. The ointment is considered very potent, therefore, it is used only as directed by a doctor. The price of one tube is 170 rubles, and the duration of treatment is from 7 to 12 days.

Dezrinit

Spray for systemic therapy of acute and chronic sinusitis, which contains a synthetic antibiotic - mometasone, which has anti-inflammatory and anti-allergic effects at the same time, which is very rare for antibacterial drugs. It differs from analogues in that it practically does not cause side effects. In order to get rid of sinusitis, the patient should use the drug at least 2 times a day for 8 days. The cost of the medicine is from 340 rubles per spray can.

Dexamethasone

These are antimicrobial drops that are used in the general treatment course, if the patient has sinusitis in a complicated form, and the negative consequences of the disease have spread to eyeball. In this case, a person should daily apply 1-2 drops of this drug to the nasal cavity and inflamed eyes. Approximate terms of therapy - from 5 to 10 days. Before using the medication, it is recommended to consult an otolaryngologist and an ophthalmologist. The price of Dexamethasone antibacterial drops is 450 rubles per bottle.

Dimexide

Liquid antiseptic, which is used in the treatment paranasal sinuses, as anti-inflammatory drops and a means for local tissue warming. To do this, Dimexide is diluted 1 to 1 with saline and instilled into the nasal cavity 2-3 times a day. Also, this drug can be used to rub the surface of the face in the area of ​​the sinuses. The drug is characterized by an increased tendency to provoke an allergic reaction of various types, therefore, when using it, this fact must be taken into account. The cost of the drug is 45 rubles.

Dioxidine

Broad-spectrum antibacterial agent. It is effective if sinusitis was provoked as a result of infection with Proteus vulgaris, Pseudomonas aeruginosa, staphylococcus aureus, Friedlander's bacillus, streptococcal infection. Helps to get rid of microorganisms that are resistant to sulfonamides. It is introduced into the patient's body in the form of intramuscular injections. The terms of treatment range from 7 to 14 days and depend on the dynamics of progress towards recovery. The price of antimicrobial injections is 270 rubles per pack of 10 ampoules.

Doxycycline

Semi-synthetic antibiotic, part of the pharmacological group of tetracyclines. Differs in increased bacteriostatic action due to the suppression of protein synthesis of pathogens of the purulent-inflammatory process. Released in the form of capsules yellow color. It is taken 3-4 times a day one hour before or after meals with plenty of water. Approximate terms of treatment - 10-14 days. Can be used as the main therapeutic agent or included in the general course drug therapy. The cost of the drug is 45-50 rubles per package, consisting of 20 capsules.

Zinnat

Granules of white color, which have an almost crumbly consistency. They are a potent cephalosporin antibiotic. It is active against most infectious microorganisms that can provoke sinusitis. The principle of action of the drug is that its active components act directly on the cell membrane of pathogenic microflora. Retail prices in pharmacies range from 320-340 rubles per pack.

Isofra

Anti-inflammatory spray for sinusitis, which contains the antibiotic framycetin, which is an aminoglycoside. The antiseptic effect is carried out exclusively locally and only on the focus of inflammation of the mucous membrane, where the active components of the drug got. In the affected area are gram-positive and gram-negative bacteria. Also, nasal drops help relieve swelling, restore stable air circulation. The cost of this drug is 340 rubles per bottle.

Clarithromycin

An antibacterial agent that is intended for the treatment infectious inflammation in the upper respiratory tract of the nasopharynx. Available in the form of white capsules. The disintegration of the active components of the drug occurs in the intestinal cavity, which ensures a gentle effect on the digestive mucosa. The medication is taken for 10 days, 2-3 capsules a day after meals. If necessary, the doctor can increase the dosage and duration of therapy if he sees that the symptoms of sinusitis have subsided, but have not yet completely disappeared. The price of antimicrobial capsules is 150 rubles.

Klacid

Semi-synthetic macrolide antibiotic. Pharmacological form release of the drug are white tablets. The composition of this drug includes an active substance - clarithromycin, which binds the synthesis of protein compounds inside microbial cells, disrupts their structure and leads to further death. The terms of treatment are from 7 to 10 days. It is recommended to use Klacid as an auxiliary element in the general therapeutic course. This medicine will cost the buyer 130 rubles per pack.

Levomekol

Combined drug local application which contains an antibiotic called chloramphenicol. In addition to it, the manufacturer saturated the drug with an immunostimulating substance - methyluracil, which increases the activity of immune system cells. The effectiveness of Levomekol against clostridium, streptococcus, staphylococcus, aerobic bacteria has been scientifically proven.

The drug itself has the consistency of a gel, and in the process of treating sinusitis, it is applied to the walls of the mucous membrane of the nasal canals using a special cotton swab. The price of this antibacterial agent is more than affordable, as it does not exceed 30 rubles per tube.

Lincomycin

An antimicrobial drug belonging to the category of lincosamides. Active against a large number of bacteria. Regular intake of the drug and a constant increase in its dosage allows you to completely destroy the pathogenic microflora inside the maxillary sinus already on the 7th day from the start of therapy. Available in the form of capsules, which are recommended to be taken 2 hours after a meal with a glass of warm water. The cost of the drug is 110 rubles per pack.

Microorganisms such as fungal infection, protozoa, viruses, all strains of enterococcus are not sensitive to the active components of the tablets.

macrofoam

An antibiotic that is part of the macrolide drug group. It is used for the systematic treatment of infections of the upper and lower respiratory tract. Effective against bacterial sinusitis. It has a pharmacological form of release in the form of a suspension, which initially comes in liquid form and is intended for oral use. Thus, the treatment of the disease and the suppression of microorganisms occurs from the inside without a local effect on the focus of inflammation. The price of an antibacterial drug is 250 rubles per bottle.

Miramistin

It selectively affects the bacteria found in the patient's body, destroys only the pathogenic microflora, and does not suppress the beneficial microflora contained in the intestine. The action of Miramistin is based on the direct hydrophobic relationship of the molecule with the lipids of microbial cell membranes. After regular intake of this medicine, they are fermented and methodically destroyed. It is introduced into the nasal cavity as antiseptic drops, or it is used as a solution for washing the nose. The cost of this liquid antibiotic is 95 rubles per vial.

Nasonex

Nasal spray with an antibacterial component. Contains mometasone furoate. This is a synthetic antibiotic for sinusitis. It is indicated for use if sinusitis is caused by infectious microorganisms resistant to natural penicillin. It is injected into the cavity of the nostrils 2-3 times a day for 7 days. During this period, it is possible to suppress most of the bacteria that provoked inflammatory disease nasopharynx. Included in the general course of therapy. The price of the drug is 550 rubles.

Nimesil

Non-steroidal antimicrobial agent from the category of sulfonanilides, which has a strong anti-inflammatory, analgesic and antipyretic effect. Produced in the form of white granules, which are designed to dissolve in distilled water and prepare a suspension. A ready-made remedy for sinusitis is taken 1 teaspoon 3 times a day 15 minutes before meals. The total duration of therapy is 10 days. The drug is difficult to classify as publicly available, since its cost is about 700 rubles per pack.

Polydex

According to its pharmacological properties, it is transparent antiseptic having a yellowish tint. Neomycin and class B polymyxin are the main antibiotics, due to the presence of which a positive therapeutic effect is achieved in the impact on the inflamed maxillary sinuses. It is used as anti-inflammatory drops that are injected into the nasal cavity 3 times a day for 7-10 days. Polydex can also be added to the composition of combined solutions intended for washing the sinuses. The price of the solution in retail pharmacy chains is 220 rubles per bottle. Not recommended for use in patients with a tendency to allergic reactions.

Protargol

A liquid antibiotic, the medicinal properties of which are achieved due to the presence of silver ions or salts in its composition. This active substance inhibits the reproduction of Gram-positive and Gram-negative bacteria by disrupting their protein compounds. The drug itself is available in the form of a nasal spray, so the effect on the patient's body is limited exclusively to local effects. Due to the absence of a toxic effect from silver molecules, it is approved for use in the treatment of children under 5 years of age, pregnant women and breastfeeding children. The cost of the drug is 160 rubles per vial.

Rinofluimucil

Nasal spray containing acetylcysteine quick withdrawal swelling of the mucous membrane and thinning of too thick mucus. Indicated for use in patients who, according to the results diagnostic examination was established infectious sinusitis with abundant accumulation of purulent exudate. Therapy with Rinofluimucil for 10 consecutive days avoids surgical intervention by sinus puncture. Due to the mucolytic properties of the drug, the fluid from the sinus leaves naturally. The price of one bottle with this medication is 550 rubles.

Sinupret

Natural antibiotic, which contains extracts of medicinal plants with antimicrobial properties. It is produced in the form of tablets, coated with a protective shell, so that the breakdown of the components of the drug is carried out directly in the intestines of the patient. It has a decongestant, secretory, and immunostimulating effect. In addition to antibacterial properties, the substances that make up Sinupret inhibit the reproduction of various strains of respiratory viruses. The cost of the drug is 330 rubles per pack of tablets.

Sinuforte

An antibiotic for sinusitis based on cyclamen, which exhibits a complex antiseptic effect. Indicated for use in purulent sinusitis, accompanied by the course of acute inflammation. It can be used as an independent drug, or as part of a general therapy.

Regular use of Sinuforte ensures the prevention of complications of inflammation in the paranasal sinuses.

Produced as a nasal spray, which must be applied to the nasal cavity in the morning and evening for 10 days. The price in retail pharmacy chains is 800 rubles per vial.

streptocide

A broad-spectrum antibiotic from the group of sulfonamides. It is actively used by otolaryngologists for the treatment of sinusitis of all forms and varieties. Effective against Staphylococcus aureus, streptococcal infection, Proteus, Pseudomonas aeruginosa, pneumococci. In the treatment of paranasal sinuses, 1 tablet of streptocide is dissolved in 5 ml. saline, and the resulting liquid is instilled into the nose as drops. Approximate terms of treatment - from 7 to 12 days. The drug is distinguished by its availability, high therapeutic benefit and ease of use. In addition, he has virtually no side properties. One package of this medicine costs 15 rubles.

Sumamed

Hard gelatin capsules containing a potent macrolide antibiotic. After entering the bloodstream, the drug begins to actively act on the inflamed mucous membrane of the paranasal sinus, as well as its epithelial tissues. When interacting with pathogenic microflora, it performs the function of removing nitrogenous compounds from bacterial colonies, which they need for development. As a result, their mass death occurs. It is taken no longer than 10 days in a row. The cost of a pack of tablets is at the level of 200 rubles. This medication does not require a special prescription from your doctor.

Suprax

Tableted antibiotic based on cefixime. It is considered a semi-synthetic drug, which is included in the drug group of third-generation cephalosporins. It is used to treat bacterial sinusitis caused by pathogenic microflora that has acquired or natural immunity to penicillin. It is taken 3-4 times a day for 7 days. The first therapeutic effect occurs already on the 3rd day from the start of treatment. If necessary and at the insistence of a doctor, the duration of the medication can be increased up to 14 days. The price of the drug in a pharmacy is 350 rubles.

Tavanik

It is used to rid the patient of complicated forms of sinusitis, when extensive inflammation has passed to the circumferential tissues in the region of the facial disc, or has significantly impaired their functionality. The pharmacological form of release of this drug is intravenous injection. The dosage is determined on an individual basis based on the severity of the diagnosed disease, the weight of the patient, the presence or absence of positive dynamics towards recovery. The main active ingredient of Tavanic is levofloxacin.. The cost of a package of medication, which includes 10 ampoules, is 300 rubles.

Tafen nasal

The composition of this nasal spray for inflammation in the maxillary sinuses includes the substance budesonide, which is considered a potent antibacterial agent. It is also effective for seasonal sinusitis of an allergic nature of origin. It practically does not cause side effects, and if they occur, then their manifestation is limited to the mucous membrane of the nasopharynx and nothing more. The drug dilutes too viscous mucus that has accumulated at the mouth of the sinuses, which helps to avoid surgical operation puncture with the installation of a drainage system. The buyer will cost this medicine 270 rubles per bottle.

Flemoklav Solutab

Semi-synthetic antibiotic, which is produced in the form of tablets. The main active ingredient of this medication is amoxicillin, which has proven effective against most gram-positive and gram-negative microorganisms. It also contains clavulanic acid, which destroys protein compounds of bacterial microflora. Flemoclav is taken only as directed by a doctor. The recommended dosage is 2-3 tablets per day with an interval of 4-6 hours. Drink 30 minutes after eating. The average cost of this drug is 180 rubles.

Flemoxin Solutab

White tablets, which are indicated for use in patients with sinusitis, in whom, according to the results of a diagnostic examination, pathogenic microbes such as Staphylococcus aureus, pneumococcus, streptococcus, enterococcus, Pseudomonas aeruginosa were found. The drug helps prevent the accumulation of purulent exudate inside the sinuses, which helps to avoid most severe complications and negative consequences for the body. The duration of treatment with Flemoxin lasts on average up to 10 days. It is not recommended to take the medication longer so that the pathogenic microflora does not get used to the active ingredient of the drug.

Fluimucil

Yellow granules that have an orange flavor that gives off bitterness. They are intended for the patient to independently prepare a suspension based on them. The suspension is taken orally 3 times a day. Dosage and concentration is determined by the attending physician based on the form of sinusitis, as well as the severity of its course. Pharmacological properties drug are antibacterial and secretory effect.

At the same time, it inhibits bacterial activity and thins thick mucus at the mouth of inflamed sinuses. The price of an antimicrobial agent is 280 rubles per pack of granules.

Furacilin

Contains in its composition an antibiotic - nitrofural, which is effective against all strains of staphylococcus, streptococcal infection, pathogens of gas gangrene. With sinusitis, it is used as a solution based on ethyl alcohol, and the tablet form of this drug. Tablets can be prescribed for internal use, and antiseptic drops are made from an alcohol solution. To do this, just draw 2.5 ml into a disposable syringe. Furacilina and a similar volume of saline, mix and instill into the nasal cavity 2 times a day. The duration of therapy is 7 days, and the cost of the medicine is only 45 rubles.

Chlorophyllipt

It has an antibacterial effect against most bacteria that are naturally resistant to such drugs. Accumulates in all epithelial tissues. Within 30 minutes after its application, it reaches the peak of its concentration in all fluids in the patient's body. Available in the form of ampoules for intramuscular injection. The average duration of maintaining a bactericidal concentration in the blood after an injection is 6 hours. After this, a gradual decline in the level of the active components of the drug begins due to the active work of the liver and kidneys. The cost of a package consisting of 5 ampoules is 95 rubles.

Cefazolin

It is a first-generation cephalosporin, which is well absorbed by the patient's body, regardless of his age group. It is used to treat sinusitis in children over 1 month of age. It is produced in the form of a white powder, which is diluted with saline with a ratio of 1 to 1 before use. It can be administered both intramuscularly and with the help of intravenous injections. The price of the drug is 110 rubles per 1 vial.

Cefotaxime

Cephalosporin antibiotic injection. Indicated for use in the treatment of patients with sinusitis who suffer from this disease over a long period of time and launched the disease to a complicated form. Cefotaxime is administered intravenously or intramuscularly into the patient's body. From the first days of their independent life, children are injected with medicine exclusively into a vein. Not recommended for patients suffering from acute allergic reactions. The cost of the medication is 220 rubles.

Ceftriaxone

Antibacterial agent for the treatment of purulent-inflammatory processes inside the maxillary sinus. Contributes to the suppression of extensive foci of accumulation of pathogenic infection, destroys the protein structures of the most dangerous microorganisms. It is considered a potent remedy, therefore it is prescribed exclusively by an otolaryngologist. It is injected into the patient's body. Sold in the form of cardboard packaging, which contains 6 bottles of white powder. The price of this antibiotic is 245 rubles.

Ciprofloxacin

Cifran

Sold in bottles with a total volume of 100 ml. The drug is intended for injection into the human body, which, according to the results comprehensive survey an inflammatory infection of the paranasal sinuses was found. Refers to antibiotic pharmacological group fluoroquinolones, therefore, can be used to combat bacteria that have natural immunity to penicillin. Within 7-10 days, the patient receives Cyfran injections in the morning and evening. The first therapeutic results are observed as early as 3-4 days from the start of treatment.

Erespal

An antibiotic containing in its composition a substance - fenspiride hydrochloride, intended to act exclusively on the human respiratory system. Produced in the form of white tablets, which are coated with a protective shell. Assigned to receive 2-3 times a day, 1-2 tablets. The average duration of therapy varies from 8 to 14 days. The local action of an antibacterial agent allows doctors and the patient himself to limit himself exclusively to the local effect of the active components of the drug on the human body. Only the organs of the upper respiratory tract of the nasopharynx are exposed to therapy. To enhance the therapeutic effect, it is recommended, in addition to tablets, to take Erespal syrup inside. The cost of this drug is about 300 rubles.

Sinusitis is called one of the most common diseases, when the inflammation is in the area of ​​the maxillary sinuses.

In addition, sinusitis can occur due to problems with the teeth, when you neglect the treatment of deep caries, or other ailments that can affect the teeth.

In this material, we will analyze the features of the treatment of sinusitis with antibiotics, find out their name, price, and also the form of release.

How the disease manifests itself

The reason for contacting the clinic for a consultation are the following signs:

1. 1) A feeling of fullness and pressure that has arisen in the sinuses of the nose.
2. 2) At the first stage, there may be mucous discharge from the nose, with an increase in inflammation, they acquire a green tint, and when they pass into the purulent stage, they become yellowish.
3. 3) Pain in the area of ​​the maxillary sinuses and head, which increases with bending over, in the evening the pain increases, in the morning it is usually less.
4. 4) General loss of strength, which is accompanied by a high temperature, up to 30 degrees and above. The rise in temperature is uncharacteristic.

In order to prescribe the best antibiotic to defeat precisely those microorganisms that caused sinusitis, a nasal swab is prescribed. The procedure is painless and does not take much time.

When are antibiotics needed?

First of all, before you start taking antibiotics for sinusitis, you should establish the root cause of its occurrence, as well as its causative agent. All this is necessary in order to choose the right antibiotic that will destroy the viral infection we need.

It should be remembered that in some cases, taking antibiotics can be completely ineffective and only aggravate the healing process. For example, with an allergic reaction due to which sinusitis has developed, taking these drugs will be a waste of time. In addition, if sinusitis is caused by a fungal infection, antibiotics will not help either.

In connection with these aspects, it is strictly forbidden to independently approach the choice of antibiotics for the treatment of sinusitis. Do not be lazy, go to an appointment with a qualified specialist. Thus, you will speed up recovery, as well as avoid unpleasant complications.

What antibiotics to take for the treatment of sinusitis

As mentioned earlier, it is necessary to determine the pathogen using a smear and, based on the test results, buy an effective antibiotic that is suitable for adults. This is the best solution.

Please note that if after the start of taking the medication, the relief of the condition does not occur after 2-3 days, then the antibiotic is chosen incorrectly, or resistance has formed to it, then the drug must be replaced.

Basically, certain groups of antibiotics are used. Below are the titles:

• Penicillin is the most common and preferred drug.
• macrolides - mainly used if the patient has intolerance to penicillin.
• fluoroquinolones are a synthetic drug to which bacteria have not yet "formed immunity".
• cephalosporins - in case of low effectiveness of other drugs, this group of drugs is prescribed. It is used in severe inflammatory processes.

Choosing the right drugs

The pharmacy has a large number of, both modern (Zitrolid, Macropen) and time-tested antibacterial drugs (Amoxil, Flemoxin Solutab, etc.). The choice is up to you and your doctor.

Antibiotics for sinusitis in tablets

Let us consider in more detail which antibiotics for the treatment of sinusitis are available in the form of tablets:

1. 1) macrofoam- a common drug that belongs to the group of macrolides, the active substance is midecamycin. Effective against pneumococcus and Haemophilus influenzae. Adults take for 2 weeks, 3 times a day after meals. An hour after ingestion, the maximum amount of the active substance will be in the blood.
2. 2) Augmentin- belongs to the group of semi-synthetic penicillins that have protection, in this case it is clavulanic acid. It has wide range action and complexity. Refers to antibiotics of the 3rd generation. Treatment with the drug should not be continued for more than 14 days. Side effects include vomiting, nausea, dysbacteriosis.
3. 3) Sumamed- a modern and popular antibiotic, which is often used for sinusitis and other diseases. Belongs to the group of macrolides. Take 1 time per day, 2 hours after, or one hour before meals. The course of treatment will be no more than 5 days.
4. 4) Flemoxin Solutab- effective and resistant to the influence of gastric juice. Belongs to the category of penicillins. When taking, listen to the doctor's recommendations, this will help speed up recovery.
5. 5) Amoxiclav - is prescribed for sinusitis, otitis, bronchitis and other diseases, has a wide spectrum of action and belongs to the group of semi-synthetic penicillins that can destroy the walls of bacteria. Shown mainly for adults only.
6. 6) Zitrolide- has an antimicrobial effect, belongs to the representatives of the macrolide group. Apply once a day, 1 hour before or 2 hours after a meal. Released by prescription.

Antibiotics for sinusitis in injections

1. 1) Ceftriaxone- intended for treatment infectious diseases, is a derivative of penicillin. Belong to the 3rd generation. Mainly used during the acute phase of sinusitis. Sold in the form of a powder for the preparation of a solution for intravenous and intramuscular injections. Contraindicated during pregnancy.
2. 2) Cefazolin- is a semi-synthetic cephalosporin antibiotic, has a pronounced antimicrobial effect. After administration, it is rapidly absorbed, the concentration in the blood lasts for 12 hours. It is necessary to dilute the drug in 4-5 ml of isotonic sodium chloride solution, or use ordinary water for injection. Possible manifestation of allergic reactions and gastrointestinal disorders.

Antibiotics for sinusitis - drops or spray

1. 1) Isofra- the most popular remedy in the form of a spray, it is preferred to use it instead of injections and tablets. Apply 4-6 times a day, it is necessary to puff alternately into each nostril. The course of treatment is a week. Before use, the nose must be cleared of snot.
2. 2) Polydex with phenylephrine- has antibacterial and vasoconstrictive action. It is used in the form of a spray 3-5 times a day, the duration of treatment is around 7 days. Contains the antibiotics neomycin and polymyxin.

The reaction to the ongoing therapy should appear within 2 days, if this did not happen - the selected drug is ineffective, and there is no point in taking it further. Requires replacement with analogues.

Dosage and duration of treatment is selected individually, for advice, contact your doctor. Uncontrolled intake can lead to a significant deterioration in the human condition, as well as the development of resistance of the microorganism to the selected drug.

Which doctor should I contact for treatment?

Antibiotics for sinusitis in some cases become the only correct solution to the problem. They help to get rid of an infectious lesion, clearing the paranasal sinuses from the accumulation of purulent masses.

Maxillary sinusitis is dangerous with complications that arise if the patient did not cure the disease on time or he was prescribed the wrong therapy. In such a situation, there is a possibility that the infection will spread from the sinuses to the lungs or to the brain. This is fraught with pneumonia or meningitis.

Drugs for treatment should be prescribed by an otolaryngologist. The selection of optimal drug therapy depends on it, taking into account the characteristics of the course of the disease and the patient's well-being. A well-chosen antibiotic for children and adults with sinusitis is the key to a quick recovery.

What is the need for antibiotics

Mucosal inflammation maxillary sinus- a fairly common ailment that has an infectious origin. The main reasons for its development include:

• viral and bacterial lesions that provoke severe prolonged rhinitis;
• simple hypothermia of the body;
• fungal infections;
• complications after influenza or acute respiratory infections;
• allergic reactions.

General symptoms - pain in the head, increased temperature regime, acute sensitivity in the face, pain in the eye sockets and frontal part, copious nasal discharge. Sinusitis leads to a violation of the outflow of secretions secreted by the mucosa.

This aggravates the course of the disease. The vital activity of pathogenic organisms turns mucus into pus. If you do not start to treat the disease on time, it can become chronic.

As a rule, pathogenic or opportunistic bacteria are the cause of inflammatory processes in the paranasal sinuses. It follows from this that antibacterial agents for this disease are first-line drugs.

We are talking about effective antibacterial drugs of synthetic or biological origin, the action of which is aimed at eliminating pathogens and preventing their reproduction.

Treatment of sinusitis with antibiotics is indicated in cases of a severe form of the course of the disease in order to avoid risk to the life of the sick person and to prevent its transition to the chronic stage.

Antibiotic medications are used in therapy, related to different forms release. We are talking about packages with tablets, sprays and nasal drops, suspensions, as well as ampoules with a substance for intramuscular injections. All of them are effective regardless of the method of use.

Unlike antiseptics, they can be used:

• externally, in the form of injections;
• orally;
• rectally;
• vaginally (introduced in the form of suppositories).

In order to quickly select the most suitable antibacterial medicine, it is necessary to undergo special studies that will help determine the sensitivity infectious agent to one antibiotic or another.

Usually, the ENT gives a referral to the patient to take a bacterial culture, a swab from the sinuses. Based on the results of the tests, the doctor prescribes a medication to which the causative agent of the disease will be most sensitive.

Therapy with antibacterial drugs

In order to determine when with sinusitis there is a need to take antibiotics, you should understand the reasons for the development of this disease.

Types of disease

Based on the etiology, maxillary sinusitis is divided into the following categories:

bacterial origin

Pathogens include many pathogenic and conditionally pathogenic microorganisms. We are talking about pneumonia, pyogenic or viridescent streptococcus, Staphylococcus aureus, Haemophilus influenzae or Escherichia coli, Moraxella, Klebsiella, Chlamydia, Mycoplasma, Proteus and others.

The lesion manifests itself when bacteria penetrate into the maxillary sinus through the upper respiratory tract (in the form of rhinorrhea, tonsillitis, pharyngitis), into the dental system (in the form of caries, flux, periodontitis) or into common system blood supply (scarlet fever with measles). It can be unilateral and bilateral. More common purulent than catarrhal (only swelling).

Viral in origin

This variety is caused by rhinoviruses, coronavirus, adenovirus, enterovirus, influenza A and B, parainfluenza. It develops mainly from seasonal colds. It is only bilateral. Usually catarrhal. It goes away on its own within one to two weeks.

Does not require antibiotics. However, in the case of a protracted illness (flu or SARS), it can be complicated by a bacterial lesion with an accumulation of purulent discharge. Then antimicrobial therapy is prescribed.

mixed type

When the origin of the disease is due to several reasons at the same time. We are talking about viruses, bacteria, fungi and allergens. An exacerbation of such sinusitis is fraught with a chronic form. With it, both sinuses are affected at once. Its course is accompanied by frontal sinusitis, ethmoiditis or sphenoiditis. It happens purulent, catarrhal, serous, exudative.

Selection of medicines for the treatment of mixed viral-bacterial maxillary sinusitis containing antibiotic active substance, is carried out by the ENT doctor with all care, taking into account the results of the research and analyzes of the patient.

allergic origin

Accompanied by bilateral inflammation of the sinuses, bouts of sneezing, copious discharge of nasal mucous masses. Antibiotic therapy is not needed in this case.

fungal infection

Caused by a fungal infection in combination with a weakened immune system. This is a rare type of sinusitis, in which antibiotic drugs are not prescribed.

medical

Caused by uncontrolled and long-term use of drugs. With this variety, the mucous membrane of the paranasal sinuses is affected. This condition leads to disruption of the normal operation of the filter cilia, the main function of which is the evacuation of mucus.

Most often it develops as a result of the abuse of nasal sprays and drops that have a vasoconstrictive effect. Does not require antibiotic therapy. It becomes necessary when a bacterial infection joins this type of sinusitis.

Traumatic origin

Caused by mechanical damage to the mucous membrane of the paranasal sinuses. It is characterized by the accumulation of mucous masses in them along with blood, an inflammatory process. Antibiotics are an essential part of treating this condition.

Purpose of treatment

The appointment of the optimal antibacterial drug in case of sinusitis, its dosage, is carried out by the doctor, taking into account the following information regarding the patient:

1. Case histories. The specialist finds out the circumstances of the occurrence of the disease state and its symptoms. The latter includes the presence of fever in the patient, signs of intoxication, pain, mucous secretions and their characteristics. The ENT will be interested in the question of how long the malaise lasts and whether the patient took any medications at his discretion;
2. The results of examinations and analyses. When diagnosing this disease, there is a need for an x-ray, general analysis blood, bacterial culture;
3. Age category of the patient and special conditions such as pregnancy and period breastfeeding among women;
4. Information about which antibiotics were previously taken by the sick person. This information is necessary for the doctor to find out the effectiveness of certain types of antibacterial drugs in this particular case.
5. The presence of the patient chronic diseases, allergies, work problems of cardio-vascular system like an arrhythmia. These data are necessary because many antibiotics have contraindications for use in the form of similar health problems.

The most effective drug is considered to be the one to which the causative agent of the disease has sensitivity, and to the use of which the patient has no contraindications. The drug should not pose a threat to the health and life of the patient.

Varieties

All antibiotic agents are divided into several large groups:

1. Bactericidal, causing mass destruction of bacteria.
2. Bacteriostatic, inhibiting the growth of bacteria.

Choice drug treatment with inflammation of the paranasal sinuses, the doctor carries out, taking into account the severity of the disease and the presence of concomitant diseases in the patient.

Systemic antibiotics come in several forms. We are talking about tablets, capsules, preparations for injection. Topical medicines with antibacterial properties come in the form of a spray or nose drops.

The latter are highly effective as an independent therapy for mild cases of the disease and as part of a complex treatment of severe cases in combination with systemic medications.

According to their chemical structure, antibiotics are divided into groups:

Penicillins

It gives good results with almost no side effects relatively easily accepted by the patient's body. Related drugs are ineffective against penicillin-resistant microorganisms. The most popular of them are:

• inexpensive "Ampicillin";
• "Amoxicillin";
• "Augmentin";
• "Amoxiclav";
• "Flemoxin".

A drug called "Amoxicillin" is prescribed most often. This is an effective medicine for sinusitis. It is important to know how to drink such medicines correctly, otherwise they may threaten with complications and lack of positive results. You should strictly adhere to the doctor's instructions regarding the dosage, frequency and duration of their administration.

Macrolides

They are used if the doctor has diagnosed a mycoplasma infection in a child, adolescent, adult patient, which is not amenable to therapy with other types of antibiotics. In such situations, macrolides are prescribed:

• "Azithromycin";
• "Clarithromycin";
• "Sumamed";
• "Macropen".

These funds are also used for intolerance to penicillins.

Cephalosporins

These are “strong” antibacterial drugs, which it makes sense to prescribe in severe cases of the disease and when therapy with more gentle medications does not give positive results. These include:

• "Ceftriaxone";
• "Cefuroxime";
• "Supraks";
• "Cefazolin";
• "Cefotaxime";
• "Cephalexin".

Fluoroquinolones

These are synthetic drugs, to the action of which there is no developed resistance in most pathogenic microorganisms. In the list of drugs in this group, you can see "Ofloxacin", "Moxifloxacin".

What antibiotics should be taken for sinusitis in patients who, for one reason or another, are not able to be treated with tablet forms?

For such situations, local antibiotic therapy with the use of drugs like Isofra, Bioparox, Polydex is relevant. These are nasal sprays and drops that effectively destroy the bacteria that caused the infection of the upper respiratory tract.

Their use helps to facilitate breathing. Due to their local effect, accumulation occurs in the focus of inflammation. medicinal substances, due to which the speedy healing of the sick is ensured.

Taking during pregnancy

Antibiotics for maxillary sinusitis during pregnancy are used only with development acute form. They are prescribed as a last resort, if the possible benefits outweigh all the likely risks for a woman in a position and her child. Many antibacterial drugs are categorically contraindicated for pregnant women, for example, Lincomycin.

Of those that can be prescribed to a future mother, the most popular and relatively cheap is Azithromycin. Also, the doctor may prescribe Spiramycin. It is considered the safest during this delicate period.

As an alternative to tablets, other procedures are used, including the introduction of local antibacterial agents (Isofra, Bioparox) into the paranasal sinuses. According to experts, these drugs are effective.

Antibiotics for the treatment of children

Such drugs in the treatment of maxillary sinusitis in children are rarely used, only when advanced stage ailment that has passed into chronic form. Their treatment is relevant in cases where the disease poses a great danger to the child's body.

Antibiotics are selected by the doctor, taking into account well-being little patient, the course of the disease and the consequences. For treatment, modern local medicines are selected, such as Bioparox with analogues like Fuzafungin and Hexoral.

They are available as nasal inhalers and oral administration. Side effects from these drugs are minimal. However, for babies under two and a half years of age, their use is contraindicated.

Dr. Komarovsky believes that it is effective to use the latest generation of antibiotics such as macrolides, such as Azithromycin, for the treatment of this disease in children. How much and how often to take the medicine is determined by the attending physician.

A course of treatment

Drinking medicines should be a course lasting up to fourteen days. In rare cases, it can stretch for sixty days. Antibacterial therapy is prescribed by the ENT for manifestations of intoxication in the patient's body.

If necessary, the drug is administered intramuscularly. To remove mucosal edema, drugs with a vasoconstrictive effect (Nafthyzin, Galazolin, Sanorin) and modern mucolytics (Fluimucil, Sinupret, Sinuforte) are additionally used.

In difficult situations, they will also need to be sanitized with antiseptics, followed by antibiotics. With a long course of the disease, drugs are prescribed with antimicrobial action. In such cases, therapy using macrolides, azalides, beta-lactamides, and fluoroquinolones is used.

Usually already on the third day after the patient begins to use them, he begins to feel better. If there are no positive results of treatment, the doctor will prescribe another antimicrobial medication that is more effective in relation to the causative agent of the disease.

When prescribing an antibiotic, the doctor takes into account the individual physiological data of the patient, adult or child, whether he has concomitant ailments. Otherwise, the treatment of inflammation of the maxillary sinuses with the use of such drugs is a danger to the life of the sick person.

Antibiotics are an integral part of the complex treatment of sinusitis. Against the background of therapy, the risks of serious complications are reduced, pathogenic microflora - the pathogen is destroyed, breathing and natural ventilation of the maxillary sinuses are restored. Antibacterial therapy is selected purely individually for each patient, based on multiple criteria. Effective antibiotics are the key to a successful recovery of the patient.

Overview of effective antibiotics with names and prices

For the treatment of sinusitis, local and systemic antibiotics are used. In rare cases, a combination of both types of drugs and other drugs for the complex treatment of the disease is possible.

Local antibiotic therapy

The advantage of topical preparations is ease of use and minimal absorption. active substance into the systemic circulation. Used at an early stage of exacerbation of sinusitis for the timely prevention of infectious complications.

Intranasal drops "Polydex"

The local remedy Polydex is used in complex treatment all types of sinusitis, including sinusitis, frontal sinusitis, ethmoiditis of a bacterial nature. During treatment, the following therapeutic effects are noted:

elimination of the inflammatory focus;

inhibition of pathogenic activity of bacterial microflora;

reduction of puffiness;

restoration of nasal breathing.

On the early stages it is enough to use as monotherapy along with regular hygienic washing of the sinuses. The effectiveness of the drug is due to its active composition:

dexamethasone (a hormonal component that has an anti-inflammatory effect);

phenylephrine (anticogestant for vasoconstriction, elimination of puffiness, restoration of mucous membranes);

neomycin (an antibacterial agent that negatively affects the microbial environment);

polymyxin (an antibacterial component that enhances the action of neomycin).

A drug absolutely contraindicated in children early age in the treatment of rhinitis, during pregnancy and lactation (possibly with the permission of the attending physician), with glaucoma. It is unacceptable to use at the terminal kidney failure, disorders of the hepatic structures, some blood diseases.

At professional athletes long-term treatment with Polydex may give positive result during doping tests.

With caution, the drug is prescribed after the introduction of an anti-tuberculosis vaccine or a vaccination against polio. A combination with any antibiotics from the aminoglycoside group is unacceptable, but a combination is likely as a complex therapy with systemic drugs various groups. Given the complex composition of the Polydex preparation, the appointment should be agreed with the attending specialist. The average cost is from 350 rubles.

Isofra with sinusitis

Antibacterial topical therapy. The drug is based on framycetin sulfate, which is an antibiotic of the aminoglycoside group. Intranasal injections allow you to distribute the main component throughout the nasal cavity, including the maxillary sinuses. The active ingredients are effective against many gram-negative and gram-positive strains:

staphylococcal infection;

enterococci;

klebsiella;

Pseudomonas aeruginosa (or hospital infections);

haemophilus influenzae.

Aerosol spraying helps to deeply distribute the antibiotic for a therapeutic and prophylactic effect on the complications of sinusitis. Mandatory conditions for prescribing the drug are:

absence of inflammation caused by pneumococcal infection, hepatitis, S. maltopilia strain;

preservation of the integrity of the mucous membranes of the nose.

It is unacceptable to use for the treatment or washing of the nasal cavities after a puncture or surgical manipulation. Inadequate application medicinal product can lead to a complicated course of sinusitis, to chronic pathological inflammation. The average cost is 280 rubles.

Spray Bioparox

Bioparox Spray is a modern antibiotic of a new generation, however, over time, its effectiveness against many strains is noticeably reduced. This is due to uncontrolled release from pharmacy chains before prescription and inadequate use "for any reason." The constituent components of the drug are:

fusafungin;

anhydrous ethanol;

norflurane (aka propellant);

• isopropyl myristate.

The composition contains aromatic additives that facilitate the use of the drug in patients childhood. Aroma components are based on natural extracts, which is absolutely safe when combined with antibacterial components.

Bioparox is prescribed only for catarrhal sinusitis, when the symptomatic picture is weak. If about 3-4 days have passed since the onset of the disease, then it is impossible to cure inflammation with Bioparox alone. Usually, treatment is supplemented by the appointment of systemic antibiotics. If the symptoms increase during therapy, it is obvious that the effect of the spray is not enough to fully influence the bacterial microflora in the sinus cavity.

When spraying, the smallest particles of the drug are delivered deep to the nasal cavities and mucous membranes. At the same time, absorption into the systemic circulation is minimal. Bioparox is used with caution during pregnancy and lactation due to the lack of research data on this group of patients.

The occurrence of severe side effects is rather rare. Typically, patients may complain of short-term skin rashes (of a local nature), dryness and burning of the mucous nasal passages. The average cost is from 450 rubles.

Systemic antibiotics

Systemic antibiotics - drugs for oral, parenteral or intramuscular injection. The funds of this group are considered the most promising in relation to the potential risks of complications. Systemic antibiotics are also prescribed for complications. The following are considered effective of systemic antibiotics for sinusitis:

In the absence of the effectiveness of antibiotics for 2-3 days, with the persistence of symptoms of exacerbated sinusitis or aggravation of the general condition of the patient, it is very important to replace therapy, mainly with drugs of the fluoroquinol group.

Injectable drugs

effective drugs against bacterial sinusitis and its complications are cephalosporin antibiotics for the preparation of solutions for intramuscular injection. For therapeutic purposes, the following drugs are usually used:

In the presence of intolerance to antibiotics of the fluoroquinol group, other injectables are prescribed: Gentamicin from the aminoglycoside group, Lincomycin from the lincosamide group, Imipenem from the carbapenem group. Typically, injectable antibiotics are prescribed in a hospital during hospitalization of a patient with exacerbation of sinusitis with characteristic symptoms. At outpatient treatment it is important to follow a strict treatment regimen and course duration.

Results

Effective and inexpensive antibiotics for sinusitis are drugs cephalosporin series. Among systemic oral antibiotics, macrolides or penicillins are more commonly used. The most effective names are:

Meropenem;

Ceftriaxone;

Gentamicin;

Tobramycin;

Cefuroxime;

Azithromycin;

Clarithromycin;

Cefpodoxime;

Regardless of the severity of the course of sinusitis, it is important to consult a doctor for its adequate treatment. Given the dangerous localization of the inflammatory process (maxillofacial bone, communication with the brain, other sinuses, sphenoid bone), the risks of complications are quite high. Especially dangerous is the development of meningeal symptoms, sepsis, suppuration of bone tissue.

Modern otolaryngology considers the appointment of antibiotics - the only adequate measure in the treatment of sinusitis (bacterial or complicated by the addition bacterial infection). Acute sinusitis quickly flows into chronic, so it is so important to start the correct and timely treatment.

Diseases, and the bacterial origin of inflammation is obvious, the matter remains small - the choice. What is it based on and how real professionals choose a medicine that can defeat the infection, we will tell in this article.

Acute sinusitis: the best antibiotics - penicillins

The use of antibiotics in acute sinusitis has been extensively studied. We do not need to experiment on our body to find out which drug will help and which will not. Everything has already been clarified before us, and our task is simply to have this information.

IN last years The principles of treatment of acute sinusitis have changed somewhat. So, the position of one of the most popular drugs before was shaken so much that it was almost discounted. The use of Amoxicillin - leading penicillin antibiotic- in acute sinusitis was studied in a randomized placebo-controlled trial. The experiment involved 166 patients with uncomplicated sinusitis. Amoxicillin was prescribed to 85 patients, and placebo - a dummy drug - to 81 patients. On the third day of treatment, there was no difference in the condition of the two groups of patients. On the seventh day, patients in the Amoxicillin group reported little improvement. On the tenth day, 80% of patients in both (!) groups felt a marked improvement or completely recovered. Thus, the low effectiveness of unprotected Amoxicillin in acute sinusitis is considered almost obvious. Why is this happening?

In fact, everything is quite simple: too many microorganisms that cause acute inflammation of the maxillary sinuses produce beta-lactamase, a special enzyme that destroys the beta-lactam ring of penicillins.

The decrease in the effectiveness of Amoxicillin prompted the formation of new principles. They regulate the use of protected penicillins, in particular, the combination of Amoxicillin with clavulanic acid, for empirical antibiotic therapy in both adult and pediatric practice.

Penicillins with and without clavulanates

Protected by clavulanic acid, the antibiotic covers the entire spectrum of microorganisms that provoke acute sinusitis. In addition, the combination of Amoxicillin with clavulanic acid is also used to treat chronic sinusitis. Nevertheless, it cannot be said that the protected penicillin has completely replaced the good old Amoxicillin. Some Western publications still recommend the latter as a first-line drug.

But domestic doctors prefer certainty in the result, so the appointment of Amoxicillin to adult patients is the exception rather than the rule. Most often, pediatricians resort to Amoxicillin in the treatment of children with limited experience in dealing with bacteria.