Euthyrox 25 mg instructions for use. How to take Eutiroks: indications, dosage, reviews. Application in childhood

Insufficient functionality of the thyroid gland, which produces the hormones necessary for human life, is compensated by Eutirox tablets. Its main component is levothyroxine, an artificial analogue of thyroxine, a thyroid hormone. Thyroxin regulates activity nervous systems s, as well as cardiovascular and, in addition, indirectly affects all organs and systems of the human body.

The drug Euthyrox is available in tablet form, 25 pieces in a blister. Euthyrox instructions for helping patients are in each package of medicine.

How to take Euthyrox

The dosage of the drug is calculated based on the individual characteristics of the patient, his weight, age and symptoms of the disease. In the annotation to the tablets, you can find tables for calculating the dose. Tablet dosing accuracy can be achieved by relying on nine basic dosages from 25 to 150 mcg.

Treatment begins with a minimum maintenance dose, gradually brought to the required therapeutic dose.

Euthyrox tablets have contraindications for use:

Exceeding the required dose leads to adverse effects, for the removal of which beta-blockers and corticosteroids are used.

Overdose symptoms:

  • tremor;
  • sweating;
  • disturbed emotional state;
  • insomnia;
  • violation of the heart rhythm;
  • dyspepsia;
  • hormonal problems;
  • baldness.

Instructions for use of the drug Eutiroks

Euthyrox tablets are prescribed when the following disorders occur:

  • hypothyroidism;
  • diffuse toxic goiter;
  • euthyroid goiter;
  • autoimmune thyroiditis;
  • Graves' disease;
  • cretinism.

In addition, the drug is prescribed for replacement therapy after surgery in the thyroid gland, as preventive measure growth of the gland and as a means for diagnosis.

The daily dose of the drug is calculated individually and depends on the diagnosis, age and weight of the patient. The tablet is taken in the morning, half an hour before meals, washed down with clean, boiled water, it is recommended to swallow immediately without chewing.

Patients with hypothyroidism for substitution therapy are prescribed in a dosage of 1.6 mcg to 1.8 mcg. In this case, the patient must be no older than 55 years, with no cardiovascular disease in history. Elderly patients with heart disease are prescribed a dosage of up to 0.9 mcg per day. For infants, Eutirox is dissolved in water and given half an hour before the first feeding, the initial dose is 25 mcg.

Patients suffering from severe hypothyroidism should be dosed with particular caution, starting treatment at 12 mcg, with TSH tested every two weeks.

Hypothyroidism requires lifelong use of Euthyrox, in other cases, the duration of the drug is determined by the doctor.

Dosage of Artificial Thyroid Hormone

The drug is available in the form of tablets of 25 mcg, 50 mcg and in a larger dosage.

Replacement therapy for middle-aged people, in the absence of severe heart disease, begins with 1.5 micrograms per kilogram of body weight. For older patients, above 55 years old, the initial dose is 0.9 mcg. For middle-aged women, a correctly selected initial dose of up to 100 mcg per day, in one dose, for men - 150 mcg per day. Patients suffering from problems with the cardiovascular system are prescribed an initial dose of 25 mcg, in one dose, the rate increases gradually, until complete normalization hormone TSH in blood serum. If unwanted symptoms appear, concomitant diseases are treated, then the norm is adjusted by the endocrinologist.

Obesity requires a calculation of supposedly correct weight.

Correction of the hormonal level in children suffering from hypothyroidism is carried out depending on age.

  • The initial dose for infants up to six months is 25 mcg, it is gradually increased to 50 mcg.
  • Starting from six months, the daily norm is from 50 to 75 micrograms.
  • For preschool children, the dose is calculated based on 7 mcg per kilogram of weight, per day it ranges from 50 - 70 to 100 mcg.
  • Schoolchildren from six to twelve years old should not exceed 150 mcg per day.
  • The dose for adolescents is approximately 200 micrograms.

For infants, the tablet is diluted in water and given half an hour before the first feeding.

To treat and relieve the symptoms of goiter, endocrinologists prescribe Euthyrox at a dosage of 75 to 200 mcg. Prevention of goiter growth after resection will require taking the drug at a rate of 50 to 200 mcg per day.

For the treatment of thyrotoxicosis, 50 to 100 mcg will be required.

Therapeutic treatment of patients with thyroid cancer requires a minimum dose of 50 mcg with a gradual increase to 300.

Euthyrox during pregnancy and breastfeeding

Treatment with an artificial hormone started before pregnancy should not be interrupted. An increase in the level of binding thyroxin requires an increase in the dosage of Euthyrox. At breastfeeding the use of the drug is completely safe, since even the highest doses of thyroid hormones do not completely penetrate into breast milk.

Overdose symptoms

An overdose of the drug occurs in rare cases, usually with a sharp change in therapeutic treatment. Clinical manifestations overdoses are also observed with individual intolerance to the components of the drug and are similar to the symptoms of hyperthyroidism.

Overdose symptoms:

Problems with the cardiovascular system, manifested as tachycardia, palpitations, angina pectoris, hypertension.

The digestive system reacts to an excess of a substance with vomiting, diarrhea. The patient loses weight, weakens, skin turn gray.

The use of Euthyrox in high doses causes a malfunction in the reproductive system of women.

An excess of synthetic hormone causes insomnia, headaches, hand tremors, and depression.

From the side of the muscular system, with an overdose of Euthyrox tablets, muscle spasms, pain and weakness are observed.

The use of Euthyrox in high doses over the years leading to sudden death from cardiac arrest.

Therapy of euthyroid goiter from 75 mcg per day, with a gradual increase to 200 mcg, the same calculations for taking pills are used to prevent the growth of the thyroid gland after its operation.

Therapy for thyrotoxicosis begins with a dose of 50 mcg for adults, 25 mcg for children, the highest dose is 300 mcg.

Thyroid cancer therapy 75 mcg per day for adults, 25 mcg for children.

Thyroid suppression test from 50 mcg to 300.

Overweight patients use the drug for weight loss, which is not particularly welcomed by endocrinologists, since small doses of the drug from 25 mcg to 50 mcg do not give the desired effect, and high doses cause complications.

For women who risk their own health for the sake of a slim figure, there are several rules that reduce the risk of overdose symptoms.

The initial dose should not exceed 25 mcg per day, in the absence of unwanted symptoms, the rate can be gradually increased.

When taking Eutherox to reduce body weight, it is imperative to keep pressure and pulse under control, the work of the digestive tract, eat right, do not smoke or abuse alcohol.

It is strictly forbidden to take Euterox for weight loss for people suffering from hypertension, as the drug can lead to increased pressure and rupture of blood vessels. It is also undesirable for women with ischemia to take synthetic hormones to reduce body weight, taking artificial hormones in such a disease leads to a heart attack.

Admission course medicinal product Eutherox for weight loss is not longer than thirty days, otherwise there is a risk of osteoporosis, myocardial myopathy, gynecomastia in men.

Modern market medical preparations wide and varied. Consumers are offered medicines of synthetic origin, herbal and hormonal agents. One of the most commonly prescribed can be called the hormonal drug "Eutiroks".

Component composition and principle of action

This drug can be characterized as a preparation of thyroid hormones, which is a left-handed isomer of thyroxine. In European countries, it was one of the first to be approved for use. It is currently prescribed to patients in over 70 countries worldwide. The drug "Eutiroks" stimulates the growth of muscle mass and tissues, speeds up metabolism. In small doses, it makes protein synthesis in the body more efficient, enhances calcification processes in bone tissues. Average doses medicinal product help the nervous and cardiovascular systems of the body work more actively, metabolic processes (fat, carbohydrate, protein) are accelerated. The tissues of the body need more oxygen. High doses of the drug inhibit the formation of a hormone produced by the pituitary gland, which, in turn, regulates the functioning of the thyroid gland.

To whom is the drug indicated?

The Euthyrox remedy, the use of which should be supervised by a doctor, is prescribed if patients have diseases such as euthyroid goiter, a persistent lack of hormones produced by the thyroid gland (hypothyroidism) in the body. In children, the extreme form of deficiency manifestation is cretinism. Further, the drug should be taken by those who have undergone surgery for oncological problems of the thyroid gland or have a toxic goiter in a diffuse form. For prophylactic purposes (prevention of new manifestations), the drug "Eutirox" is prescribed to people who have undergone surgical interventions on the thyroid gland. As a diagnostic tool, it is used in the thyroid suppression test.

Contraindications

A persistent indication to refuse to take the drug is intolerance to its components. You can not take the drug "Eutiroks" (side effects will not keep you waiting) suffering from thyrotoxicosis in the event that thyreostatic therapy was insufficient. The presence of myocarditis and myocardial infarction is also a reason to refuse to take the Euthyrox medication. In addition, the drug is not prescribed for people suffering from pancarditis in acute form who have untreated forms of pituitary insufficiency and insufficiency of the adrenal cortex.

Patients with diabetes mellitus should take the drug carefully and under the strict control of an endocrinologist. Also, one should be attentive to one's condition in patients with impaired functions of the cardiovascular system, suffering from atherosclerosis and severe forms of hypothyroidism. The doctor should also be careful when prescribing the drug to patients suffering from malabsorption syndrome.

Frequency of administration, dosing

Full information on how to take Euthyrox is offered by the instructions accompanying the drug. In general, the drug is drunk once in the morning, the entire dose at once, at least 30 minutes before meals, and washed down with water. The required daily dose depends on the disease and is selected by the attending physician. It should be noted that in case of hypothyroidism, the drug "Eutirox" is indicated to be taken for life.

In the treatment of goiter during the active period and after surgical intervention the prescribed dose of the drug ranges from 75 to 200 mcg. In thyrotoxicosis, the minimum volume is 50 mcg and can increase to 100. In the treatment of thyroid cancer, the dose from 50 mcg can be increased to 300. In hypothyroidism, the volume is calculated based on the patient's age and depends on his weight. That is, a patient under the age of 55 can be prescribed a dose of up to 1.8 mcg per kilogram of weight. If the patient is older than 55 years, the volume should not exceed 0.9 micrograms per kg of body weight.

When performing a thyroid suppression test, the dose depends on the period of time remaining before the procedure. 3-4 weeks before the test, it is 75 mcg; for 2 - 100-150 mcg, for a week - 100-200 mcg. For children with congenital hypothyroidism, the dosage depends on age. Children under 6 months are prescribed 25-50 mcg, from 6 months to 1 year - 50-75 mcg, from one year to 5 years - 75-100 mcg, from 6 to 12 years - 100-150 mcg. For children over 12 years old, the volume is 100-200 mcg.

When taking the hormonal drug "Eutiroks", side effects are quite possible, so patients should be attentive to their condition and contact their doctor at the first symptoms.

Exceeding the permissible dose, compatibility

According to patients and medical specialists, an overdose of Euthyrox is manifested by a group of symptoms characteristic of thyrotoxicosis. The most striking manifestations of excess dose include tachycardia, heart rhythm disturbance, pain in the heart. From the side of the nervous system, one can distinguish tremor (trembling hands), insomnia, restlessness, increased sweating. Lack of normal appetite and, as a result, weight loss, diarrhea can also be caused by the drug "Eutiroks". Overdose is treated by lowering the dose. Beta-blockers may be prescribed for admission, or hormones may be suspended for several days in general.

If the patient has taken extremely high doses of Euthyrox, the doctor may prescribe plasmapheresis to relieve the symptoms of an overdose. IN medical practice there have been cases of cardiac arrest in patients who have taken extreme doses for several years. In some patients, convulsions occurred if the tolerance threshold of the drug "Eutiroks" was exceeded. Reviews about the drug are rather ambiguous. But in case of manifestation of symptoms associated with an excess of the dose, treatment should be resumed very carefully. The dose should be lowered relative to the one at which an overdose in one or another of its manifestations is diagnosed.

The drug "Eutiroks" (instruction, patient reviews - to direct evidence) is not recommended to be combined with taking other medicines without the appropriate prescription of the attending physician, because the medicines may be incompatible.

Preparations

Manifestation of incompatibility

Indirect anticoagulants

The drug "Eutiroks" is able to significantly enhance their effect

Tricyclic antidepressants

The effect of antidepressants may be significantly increased

Insulin and other similar drugs

To achieve the desired effect, you need to increase the dose

Cardiac glycosides

Weakens the effectiveness of drugs

Celestyramine, colestipol, aluminum hydroxide

The concentration of levothyroxine in the blood plasma will be lower than necessary

Tamoxifen, anabolic steroids, asparanginase

Possible interaction at the level of connection with proteins.

Phenytoin, salicylates, dicoumarol, furosemide, clofibrate

The content of free levothyroxine, not bound to plasma proteins, increases

Individual patients need to increase the content of levothyroxine

Somatotropin

Growth stimulating epiphyseal zones close faster than usual

carbamazeline, rifapmycin

Increased clearance of levothyroxine

From all of the above, you can get an idea of ​​​​how an overdose of Euthyrox manifests itself. Symptoms are usually severe and action must be taken immediately. And the right to combine the intake of a hormonal drug with any other drug belongs only to the doctor.

For future mothers

For many women, the desire to become a mother is so strong that the verdict of doctors that they cannot give birth due to the presence of any disease does not serve as a sufficient reason not to become pregnant. For a pregnant woman, the “success of the entire enterprise” may depend, so to speak, on taking the drugs prescribed by the doctor. When a future mother is found to have a lack of hormones produced by the thyroid gland, the gynecologist prescribes Euthyrox for admission. During pregnancy, the drug must be taken continuously. It works instead of the thyroid gland, ensuring the normal activity of the whole organism. Cancel hormone therapy for a woman and an unborn child is fraught with serious problems. Perhaps a complication of intrauterine development, up to mental retardation. Before synthetic analogues of thyroid hormones were developed, doctors recommended abortion for medical reasons.

Sometimes it happens that the expectant mother finds out that the body lacks hormones produced by the thyroid gland, only with a mandatory examination, which all pregnant women undergo. In any case, the drug "Eutiroks", the side effects of which can be quite painful, is vital to take. However, the intake should be under the supervision of the attending physicians - a gynecologist and an endocrinologist, because the dosage during the entire pregnancy can be changed depending on what the results of TSH and blood tests are. And the condition of the child can be badly affected by both the lack of the hormone and its excess.

If a woman, even before pregnancy, knew about the lack of hormones in the body and took the Euthyrox remedy, then when it occurs, the dose of the drug should be increased. After the baby is born and during the lactation period, the mother should continue taking the medication, but carefully and under the supervision of a doctor.

Will we lose weight?

Those who wish to use the drug "Eutiroks" for weight loss, first of all, should remember that this is a preparation of thyroid hormones, and not a means for losing weight. Under no circumstances should you assign it to yourself! Small doses of the drug stimulate fat and protein metabolism, and the dosage of the average volume has a positive effect on the functioning of the nervous and cardiovascular systems. The tool is indicated for use for a fairly wide range of diseases, but nowhere is it said that it should be used for weight loss. This is a hormonal drug, and taking it without proper medical supervision can have the exact opposite effect - weight will increase.

In any case, those who take Euthyrox for weight loss should be aware that weight can decrease (namely, “may”, and not necessarily decrease) only for the reason that it speeds up the metabolism, which is the reason for weight loss. . Under no circumstances should the recommended dose be exceeded. Such actions can have a very negative impact on the state of health, disrupting the stable functioning of the heart, nervous system, and thyroid gland.

Medical experts do not recommend taking the drug "Eutiroks" solely in order to lose weight. An inaccurately selected dosage can cause a lot of side, negative effects. If, however, symptoms appear, the drug should be discontinued in order to lose weight.

Side effects

In addition to the undoubted benefits in the treatment of diseases associated with insufficient production of thyroid hormones, the drug "Eutiroks" has side effects. Its use can cause tachycardia (increased heartbeat), disrupt the rhythm of the heart and cause chest pain. The central nervous system can react to the drug with a violation of the general emotional background, insomnia. Signs such as significant weight loss, diarrhea, alopecia, impaired adrenal function in adults and kidney function in children are quite possible.

The opinion of patients about the drug

The opinions of patients taking Euthyrox are enough long time, are highly ambiguous. A separate group of people say that the drug brought them back to life. All the symptoms accompanying the lack of thyroid hormones are gone, the patients feel absolutely healthy. However, there is a considerable percentage of those who cannot refuse to take the drug, and there is simply no strength to take it because of a large number side effects.

Some patients complain of an increased sense of anxiety, manifested in tremors, bad dream, there is a feeling of fear, depression. Many people complain about the constant feeling of cold, low temperature body. Some patients say that dry cough intensifies with the drug, the skin becomes dry and cracks. However, in the presence of a bright manifestation of hypothyroidism, less of two evils is chosen - they take the remedy.

For many future mothers, the leading doctor prescribes Euthyrox during pregnancy. From someone the reviews are the most positive, the condition is improving significantly. However, there are those who have a stomach reaction to the drug (constipation, constant nausea, lack of appetite), herpes rashes appear.

Many are ready to make any sacrifice. We are talking about the drug "Euritoks", which is intended for the treatment of diseases of the endocrine system. In weight loss, it is used to normalize hormonal levels and as a fat burner. Oddly enough, but among those who are losing weight, "Eutiroks" for weight loss has long gained popularity, reviews, of which there are quite a lot on the network, are evidence of this. It remains to find out the main thing: how effective the drug is and what are the health consequences.

Description of the drug

The drug "Eutiroks" is a synthetic hormone, it is completely similar to the one that produces thyroid. It is prescribed by specialists to make up for the deficiency of the hormone for the normal functioning of the thyroid gland. The active substance in this drug is levothyroxine sodium, which, after disintegration in the human body, directly affects metabolic processes.

How does the use of "Eutiroks" for weight loss affect the body? The active drug burns and does not negatively affect muscle mass, increases efficiency and endurance, stimulates the nervous system. You need to pay attention to the last point: the drug speeds up the heartbeat and increases the load on the heart.

When is Euthyrox needed?

With some diseases of the thyroid gland, body weight increases rapidly. Everyone has long known that a lack of a special hormone provokes obesity, and an excess, on the contrary, contributes to weight loss. But let's take a closer look at the drug "Eutiroks". Instructions for use for weight loss, this drug is not recommended, respectively, for the treatment of obesity (without the appointment of a specialist) it is not intended.

But this drug really speeds up the metabolism. This suggests that he is able to break down adipose tissue. That is why Euthyrox is used for weight loss. Reviews show that this method has a lot of supporters. It is only worth considering that together with adipose tissue, the active substance can remove protein from the body, and it is important for muscle tissue.

Harm from the use of "Eutiroks"

Despite the fact that to some extent the drug really helps to reduce weight and adjust the figure, it can cause irreparable harm to health. Side effects include:

  • weakening of the heart muscle due to the active substance of the drug;
  • leaching of calcium from the body, which leads to the destruction bone tissue, the bones become more fragile and can break even with a weak mechanical impact;
  • increased excitability of the nervous system, which manifests itself in the form of irritability, nervousness, sleep disturbances.

It is difficult to call this method of losing weight safe, on the contrary, it is accompanied by a serious risk. Therefore, the use of "Eutiroks" for weight loss should be cautious. It would be more correct to think carefully before deciding on such a desperate act.

Methods of application and doses

The most necessary information, if you decide to take Euthyrox for weight loss, is the dosage. Reviews of those who lose weight in this way contain their recommendations for readers. All are somewhat different from each other.

How to actually take "Eutiroks" for weight loss? The dosage in the instructions for use for burning adipose tissue, of course, is not indicated. Therefore, you can refer to the recommendations of athletes (the main consumers of this drug).

So, how to use "Eutiroks" for weight loss? The course of treatment should not exceed 28 days, this is quite enough to speed up the metabolic processes in the body and restore the normal functioning of the thyroid gland. To minimize the negative impact of the drug on the heart, beta-blockers should be taken in parallel, it is impossible to extend the course of administration. At the first stage, the daily dose should not exceed 50 mcg, later the dose can be increased to 300 mcg. daily rate should be divided into 2 or 3 doses, the last of which should not be later than 6 pm. The drug should be taken before meals or not earlier than 2 hours after it, the tablets should be taken with plenty of water. Tablets "Eutiroks" is not a salvation from excess weight, power correction is a must.

Everyone knows how to eat right. For weight loss, even with the help of the drug "Eutiroks", you need to create a specific menu, which should not contain fatty and high-calorie foods. First of all, you should abandon flour and bakery products, sugar, semi-finished products, fatty meat and dairy products.

But it is equally important to include as much fiber and protein in the diet as possible. It is allowed to eat lean meat, poultry, chicken eggs, fish and seafood. You can eat fruits and vegetables in unlimited quantities, cereals, especially oats, will be no less useful. In total, the caloric content of the diet should be no more than 2000 kcal per day.

Why "Eutiroks" does not help to lose weight

The main reason for failures in losing weight with Euthyrox is that its active substance accelerates all processes in the human body, including the absorption of glucose. It is the excess of this substance in the diet that can lead to the opposite results. To avoid trouble, you need to review the diet and make sure that it contains as little glucose as possible, and it is better to do without it at all.

The difficulty lies in the fact that "Eutiroks" acts as a brain stimulant, for the correct operation of which glucose is necessary. Therefore, the craving for sweets only increases, you need to strictly limit yourself in the consumption of sugar.

You need to think carefully before taking a drug like Euthyrox. Doses for weight loss in any case cause unpleasant consequences for the general condition of a person. Appetite increases, working capacity decreases, insomnia appears. It is hardly possible to avoid such consequences, even if the drug is taken correctly.

Euthyrox is a drug containing thyroid hormones.

Release form and composition of Euthyrox

Eutiroks is issued in the form of white tablets, the main active substance which is levothyroxine sodium. Euthyrox tablets are available in 25, 50, 75, 88, 100, 112, 125, 137, 150 micrograms.

Excipients in tablets are: croscarmellose sodium, corn starch, gelatin, magnesium stearate, lactose monohydrate.

Pharmacological action of Euthyrox

Levothyroxine is a levorotatory isomer of thyroxine. When levothyroxine in the liver and kidneys partially turns into triiodothyronine and passes into the cells of the body, it begins to affect tissue growth and metabolism.

Eutiroks in low doses exhibits an anabolic effect on fat and protein metabolism. In medium doses, it activates growth, increases the oxygen demand of tissues, increases the activity of the central nervous and cardiovascular systems, stimulates the metabolism of carbohydrates, fats, and proteins. In high doses, it inhibits the production of thyrotropin-releasing hormone a and thyroid-stimulating hormone.

The effect of the drug is noticeable after 1-2 weeks. With hypothyroidism clinical effect noticeable after 3-5 days. Reduction or disappearance of diffuse goiter occurs in 3-6 months. The effect of the drug persists for 1-2 weeks after its withdrawal.

Indications for use Euthyrox

According to the instructions, Euthyrox is prescribed:

  • with hypothyroidism;
  • with euthyroid goiter;
  • after surgery for thyroid cancer;
  • with diffuse toxic goiter, when a euthyroid state is achieved with the use of thyreostatics;
  • for the prevention of recurrence of goiter, as replacement therapy and after resection of the thyroid gland;
  • as a diagnostic tool for the thyroid suppression test.

Contraindications to the use of Euthyrox

According to the instructions, Euthyrox cannot be prescribed for:

  • acute myocardial infarction;
  • untreated thyrotoxicosis;
  • acute myocarditis;
  • untreated pituitary insufficiency;
  • acute pancarditis;
  • untreated adrenal insufficiency;
  • the presence of high sensitivity of the body to the drug.

The drug is prescribed carefully for:

  • a history of atherosclerosis, myocardial infarction, angina pectoris;
  • arterial hypertension;
  • diabetes;
  • arrhythmias;
  • long-term severe hypothyroidism;
  • malabsorption syndrome.

Method of application and dosage of Euthyrox

Euthyrox tablets are intended for oral administration. Euthyrox is taken on an empty stomach in the morning in a daily dose at least half an hour before a meal. The tablet is washed down with 100 ml of liquid.

Daily dosage of Euthyrox:

  • euthyroid goiter - 75-200 mcg;
  • as part of complex treatment thyrotoxicosis - 50-100 mcg;
  • in the suppressive treatment of thyroid cancer - 50-300 mcg;
  • with replacement therapy in case of hypothyroidism:
  • under the age of 55 - 1.6-1.8 mcg per kilogram of weight (in the absence of diseases of the cardiovascular system);
  • over the age of 55, or with diseases of the cardiovascular system - 0.9 mcg per kilogram of weight;
  • in order to prevent recurrence of euthyroid goiter after its surgical treatment- 75-200 mcg;
  • when performing a thyroid suppression test:
  • four weeks before the procedure - 75 mcg;
  • three weeks - 75 mcg;
  • in two weeks - 150-200 mcg;
  • per week - 150-200 mcg;
  • in the treatment of congenital hypothyroidism childhood:
  • up to six months - 25-50 mcg;
  • from six months to a year - 50-75 mcg;
  • from a year to 5 years - 75-100 mcg;
  • from 6 to 12 years - 100-150 mcg;
  • more than 12 years - 100-200 mcg.

The daily dose of Euthyrox is given to infants half an hour before the first feeding, dissolving the tablet to a fine suspension in water.

The initial daily dose of Euthyrox:

with hypothyroidism during replacement therapy:

under the age of 55 - 75-100 mcg (for women), 100-150 mcg (for men) - in the absence of diseases of the cardiovascular system;

at the age of more than 55 years, or with diseases of the cardiovascular system - 25 mcg. The dose is increased every 2 months by 25 mcg until TSH normalizes;

with long-term severe hypothyroidism - 12.5 mcg. The dose is increased by 12.5 mcg at longer intervals until maintenance. In this case, every 14 days should determine the level of TSH.

In the presence of hypothyroidism, the drug is taken for life.

In thyrotoxicosis, the drug is used simultaneously with thyreostatics after the euthyroid state is reached.

Side effects of Euthyrox

According to reviews, Euthyrox is well tolerated. When using Euthyrox according to indications in recommended doses, the drug does not cause side effects.

Overdose

According to reviews of Euthyrox, an overdose of the drug is manifested by symptoms that are typical for thyrotoxicosis: heart rhythm disturbance, palpitations, anxiety, heart pain, sleep disturbance, tremor, excessive sweating, diarrhea, loss of appetite and body weight.

Overdose treatment is to reduce daily dose medications, the appointment of beta-blockers, or the suspension of treatment with the drug for several days.

Use during pregnancy and lactation

With hypothyroidism during pregnancy and breastfeeding, treatment with Euthyrox continues. But during pregnancy, the dose of the drug should be increased.

The use of this drug during pregnancy is contraindicated along with thyreostatics.

During breastfeeding, Euthyrox should be taken carefully under the supervision of a physician if indicated.

Interaction with other drugs

When taking Euthyrox according to indications simultaneously with:

  • indirect anticoagulants - their action is enhanced;
  • tricyclic antidepressants - the effect of antidepressants is enhanced;
  • insulin and oral hypoglycemic drugs - the need for these drugs increases;
  • cardiac glycosides - their effect is reduced;
  • cholestyramine, colestipol and aluminum hydroxide - the concentration of levothyroxine in plasma decreases. Therefore, Euthyrox is taken 4-5 hours before the use of these drugs;
  • tamoxifen, anabolic steroids, asparaginase - at the level of protein binding, pharmacokinetic interaction may occur;
  • phenytoin, salicylates, dicumarol, furosemide, clofibrate in high doses - the content of levothyroxine, unbound to plasma proteins, increases;
  • estrogen-containing drugs - in some patients, the need for levothyroxine increases;
  • somatotropin - accelerates the closure of epiphyseal growth zones;
  • carbamazepine, phenobarbital, rifampicin - increased clearance of levothyroxine.

special instructions

In the presence of hypothyroidism associated with damage to the pituitary gland, the doctor should find out if the patient has adrenal insufficiency. Replacement therapy glucocorticoids in this case begin before the start of treatment with thyroid hormones.

Storage conditions for Euthyrox

Euthyrox should be stored at a temperature not exceeding 25ºС.

Euthyrox is a synthetic analogue of thyroxine, a thyroid hormone used to treat hypothyroidism. Due to the hormonal action, if the dosage is exceeded, there is a risk of getting an overdose of Euthyrox with unpleasant consequences for the body.

Description of the drug

The drug "Eutiroks" is available in the form of tablets, each of which contains from 25 to 150 mg active substance- levothyroxine sodium, which is synthetic analogue thyroid hormone, as well as additional components. The recommended doses of "Eutiroks" vary depending on the expected therapeutic effect:

  • a high dosage is prescribed to reduce the concentration of a hormone produced by the pituitary gland;
  • medium - increases the activity of the nervous and cardiovascular systems, regulates growth processes and improves tissue respiration;
  • a low dose of Euthyrox is prescribed to stimulate protein and lipid metabolism.

Only a doctor can select the dosage and determine the period of treatment, depending on the individual characteristics of the patient's body and the nature of the course of the disease.

The human body absorbs the drug well. Reviews about the drug are positive: a noticeable therapeutic effect (if the use is regular) is achieved as early as 3-14 days, depending on the disease, and persistent improvements in serious pathologies are observed by patients a few months after the start of the drug. After the tablets are canceled, they stop working after one to two weeks.

Indications for use

"Eutiroks", acting as a natural thyroxine, affects the replenishment of thyroid hormones in various pathological conditions. Indications for the use of the drug - a number functional disorders work of the endocrine system, including:

  • prolonged lack of thyroid hormones (mainly Euthyrox is prescribed for hypothyroidism);
  • chronic negative effect of antibodies that the human body itself produces (autoimmune diseases);
  • an increase in the volume and mass of the gland without violating its functions;
  • recovery after surgical interventions (including surgical treatment of oncological diseases);
  • delayed mental and physical development, which is caused by hormonal causes (cretinism);
  • enhanced tissue metabolism and pathological activity of the nervous system;
  • comorbidities treated with drugs that block the functioning of the thyroid gland.

"Eutiroks", the indications for the use of which are quite extensive, is almost a universal drug that treats pathologies of the endocrine system, is used as part of complex therapy autoimmune diseases and certain conditions of the cardiovascular and nervous systems. It is sometimes necessary to start using the drug during the recovery period after surgical interventions, for preventive and diagnostic purposes (thyroid function test).

How to correctly calculate the dose and how to take the drug in each case? The answer to this question can only be given by the attending physician, based on the results. complex diagnostics the patient's condition. How long the course of treatment will last and whether there are contraindications, the specialist also decides - some patients take the remedy throughout their lives, while others need only a certain course.

Side effects of Euthyrox

Unpleasant side effects can occur, first of all, if the necessary dose of Euthyrox is not correctly selected.

Side effects also appear with increased individual sensitivity to one of the elements in the composition of the drug ( allergic reaction), non-compliance with the regimen, or when interacting with some other drugs.

If the dosage is not high enough side effect medication is manifested by symptoms of hypothyroidism:

  • weakening of concentration of attention and memory, decrease in working capacity;
  • drowsiness, fatigue and slowness;
  • work disruption digestive system, constipation and nausea;
  • swelling of the face, mucous membranes of the nose and the auditory tube (as a result, there is a decrease in hearing and visual acuity).

A patient taking too high dosages may experience the following conditions:

  • pain in the region of the heart and sternum;
  • violations of the frequency and rhythm of contractions of the heart muscle;
  • anxiety, sweating, insomnia, increased anxiety;
  • convulsions and idiopathic tremor (trembling of the trunk or limbs of unknown origin);
  • decreased appetite, weight loss, digestive disorders such as diarrhea and vomiting;
  • violations menstrual cycle among women.

Usually, the body reacts quickly to the wrong dosage, which allows you to change the course of therapy in time. Any negative consequences of taking the drug require a second consultation with a specialist to adjust the treatment regimen and dosage of the drug.

Contraindications to taking medication

The main contraindications are hypersensitivity to the components of the drug, untreated hypothyroidism, thyrotoxicosis and adrenal insufficiency, acute inflammation of the membranes of the heart or heart muscle, as well as myocardial infarction.

Pregnancy and lactation are not a serious limitation: if a woman starts using Euthyrox before pregnancy, then you can continue taking the drug while waiting for the baby.

With caution, you need to drink pills for diabetes, arrhythmia, increased blood pressure or ischemic heart disease. The use of "Eutiroks" in acceptable doses is allowed for the treatment of congenital hypothyroidism in children from birth.

drug overdose

"Eutiroks" is a hormonal drug, therefore, taken in an overdose, it causes a state of hyperfunction of the thyroid gland. The human body usually reacts to hyperthyroidism in the following ways:


In addition, with hyperthyroidism, which causes an overdose of Euthyrox, metabolic processes are disrupted. This leads to both weight loss and frequent urination, and hair loss, and thinning of the skin or nails.

An incorrectly selected treatment period and an overestimated dosage (or increasing it too quickly) threaten to squeeze ophthalmic nerve which can result in complete loss of vision.