What drugs contain the active ingredient albendazole. Albendazole - instructions for use for treatment and prevention, dosages for children and adults, analogues and price. Contraindications and side effects

1. The main component of the drug is albendazole, the action of which is aimed at combating helminths.
2. Also, the drug was developed on the basis of excipients- lactose monohydrate, corn starch, film coating mixture, sodium lauryl sulfate, magnesium stearate, povidone, anhydrous silica, gelatin, talc, methylparaben, propylparaben.

The drug is produced in the form of tablets, which have a rounded shape and a biconvex surface. They are covered film sheath, which is white. Tablets are packaged in blisters of 3 pieces. Each of them, together with instructions for use, is placed in a cardboard box.

Symptoms of a worm infestation

With the appearance of helminthic invasions in the human body, the development of the corresponding symptoms is diagnosed.

Worm infestations lead to a large number a variety of symptoms. When the first of them appears, the patient should contact the doctor, who will prescribe effective treatment with Albendazole.

The principle of the drug

With the help of Albendazole, mono- and polyinvasions are destroyed, cysts are reduced or completely destroyed in patients who suffer from granular echinococcosis.

pharmachologic effect

With impaired liver function, an increase in the maximum concentration of the active ingredient in the blood is observed. In this case, the half-life of the drug is much longer.

Indications for use

The use of Albendazole should be carried out in strict accordance with the indications.

• Cystercosis;
• Echtnococcosis;
• Toxocariasis;
• Microsporidiosis;
• Ankylostomsidosis;
• Filariasis;
• Opisthogrhoze.

The indication for the use of the drug is neurocysticercosis, in which the central nervous system affects the tapeworm. With the help of the drug, enterobiasis is treated, which occurs against the background of exposure to pinworms.

Albendazole is a helminthic infestation when impossible surgical intervention. Also this drug It is used after surgery with insufficiently long treatment before it.

Contraindications for use

Before using a medicine, a person needs to determine contraindications to it.

• Hypersensitivity to the main or auxiliary components;
• The course of infectious diseases;
• Fasciolosis in acute form;
• Diseases of the retina;
• Phenylketonuria;
• cirrhosis of the liver;
• kidney failure;
• Oppression in bone marrow hematopoiesis;
• pregnancy;
• lactation.

The use of Albendazole should be carried out taking into account contraindications, which will eliminate the possibility of developing undesirable effects.

Side effects

If the drug is used incorrectly, patients may experience the development of undesirable effects.

In most cases, they manifest themselves in the form of violations in such organs and systems:

• The cardiovascular system. Patients have increased aprerial pressure and develop tachycardia.
• CNS. Treatment is accompanied by headache, drowsiness or insomnia, disorientation, confusion, convulsions, hallucinations, anxiety.
• Hepatobiliary system. Against the background of exposure to the drug, the activity of liver enzymes transiently increases, and the appearance of jaundice and hepatitis can also be observed.
• GI tract and liver. Some patients were diagnosed with dry mouth, constipation, nausea, vomiting, abdominal pain, diarrhea, stomatitis.
• Hematopoietic system. Albendazole can cause the development of leukopenia, pancytopenia, neutropenia, anemia, thrombocytopenia.
• Kidneys and urinary system. In patients, the functioning of the kidneys may be impaired, and the development of kidney failure, proteinuria.
• Skin. Undesirable effects are manifested in the form of a rash, hyperemia, itching, reverse alopecia, urticaria, edema, dermatitis.

In the treatment with Albendazole, the development of general disorders in the form of fever, bone pain, and weakness can also be diagnosed. In some cases, sensitivity increases, which leads to anaphylactic reactions.

Method of application and dosage of Albendazole

The disease that occurs in the patient's body directly affects the features of the use of the drug.

How to use Albendazole for animals?

Therapy of animals with the drug is also carried out in accordance with the type of helminths:

• Moniesiosis and nematodes in sheep. Relies 2.5 grams of the drug per 100 kilograms of animal weight.
• Fascioliasis. For one hundred kilograms it is necessary to use 3.75 grams of Albendazole.
• Ascariasis in pigs. 5 grams of the drug per 100 kilograms of body weight.
• Ascariasis and heterokidosis in birds. 10 milligrams of the drug is expected per 1 kg of bird weight. In this case, group treatment is carried out.

Overdose

When using the drug in excessive quantities, there is:

• vomiting
• nausea
• drowsiness
• dizziness
• diarrhea
• patients are diagnosed with the development of visual hallucinations
• tachycardia
• jaundice
• respiratory distress

Application for children

Treatment with Albendazole in children under 3 years of age is allowed. The dosage is determined by the doctor in accordance with the patient's body weight.

Use during pregnancy and lactation

During the period of bearing a child, the use of the drug is strictly prohibited. Since the active components of the drug are able to penetrate into breast milk, lactation must be abandoned for the duration of the drug treatment.

drug interaction

If you take Cimetidine and Dexamethasone at the same time, the amount of Albendazole in the blood may increase. Albendazole increases the concentration in the blood of a large number of drugs. That is why when using them, you need to consult a doctor.

Interaction with alcohol

It is strictly forbidden to use Albendazole simultaneously with alcoholic beverages. Otherwise, not only a decrease in the effect of the drug will be observed, but also the appearance of undesirable effects.

special instructions

Conditions for dispensing from a pharmacy

You can buy Albendazole in a pharmacy only with a doctor's prescription.

Storage conditions and shelf life

Storage of the drug should be carried out in the original packaging in a dry place protected from light. At the same time, it is necessary to limit access to it for children. After the manufacture of the drug, its use is allowed for 3 years.

The cost of the drug

The average price of Albendazole in pharmacies in our country is 160 rubles.

Analogues

If there are contraindications to Albendazole, it is recommended to use analogues:

During the period of application of Vermox, it is necessary to carry out treatment with sorbents, which will ensure the rapid removal of worms.

Pirantel is allowed to be used in patients from birth.

Also, this medication, compared with Albendazole, causes fewer undesirable effects.

One of the best means for the treatment of helminthic invasions, Albendazole is considered - the instructions for use contain information on the dosage of the drug for treatment various kinds helminthiases. The drug is safe, but has a number of contraindications and side effects, before starting therapy, you should study the description.

Composition

Suspension - a liquid of light gray or white color, 100 ml of the drug contains 2.5 or 10 g of the main substance. Additional ingredients - alcohol, citric acid, distilled water, methylcellulose. The drug goes on sale in 100 ml glass containers or in 1000 ml polymer bottles. Albendazole suspension should be stored at a temperature not exceeding 15 degrees for 24 months.

Tablets are round, white, contain 400 mg of the active substance. Additional ingredients - beckons, lactose, starch, other components that do not have a therapeutic effect. Keep medicine at room temperature can be 36 months. average price medicinal product - 140-170 rubles, depending on the form of release and manufacturer.

Action

The mechanism of action is based on the ability of the active substance to inhibit the polymerization of tubulin, prevent the breakdown of glucose, and stop the production of ATP - all this leads to dysfunction of muscle fibers, paralysis and death of helminths.

After taking the medicine enters the intestines, penetrates into the general bloodstream, internal organs, cerebrospinal fluid. The main part of the drug is broken down in the liver, it releases substances that adversely affect the worms.

Instructions for use

The method of application of Albendazole is oral, the suspension and the drug in tablet form should be taken shortly before meals, washed down with plenty of clean water.

Important! Elderly people do not need to adjust the dosage, but in the presence of severe hepatic diseases, the drug should be taken under constant medical supervision.

Indications for use

The drug Albendazole is effective against intestinal and extraintestinal types of worms, destroys larvae and adults.

Albendazole is prescribed for therapeutic and prophylactic purposes, the drug is also used in veterinary practice.

Dosage

Adults are prescribed Albendazole 400, the treatment regimen is selected individually, taking into account the severity of the helminthic invasion.

How to take medicine

For the prevention of helminthiasis, it is necessary to take 10-20 ml of suspension, or 0.5-1 tablet per day for 2 days. The break between courses is 2-6 months.

Important! Simultaneous intake of Albendazole and fatty foods increases the rate of absorption of the drug.

During pregnancy

Albendazole has a pronounced teratogenic effect; it is strictly forbidden to take the medicine for pregnant women. Before you start taking the drug, it is necessary to conduct a diagnosis for pregnancy. Use barrier contraception during treatment.

Important! Pregnancy can be planned 6 months after the end of treatment with Albendazole in order to exclude the occurrence of developmental pathologies in the fetus.

children

Albendazole in the form of a suspension is allowed to be used in the treatment of children older than 2 years, in tablets - older than 6 years, the dosage of the drug depends on the weight of the child, the type of helminths.

Instruction for children:

• neurocysticercosis - 15 mg / kg / day for 8-30 days;
• ascariasis, ankylostomidosis, enterobiasis - once 200 mg or 15 mg / kg with an interval of 3 weeks;
• giardiasis - 10-15 mg / kg for 5-7 days;
• cestodosis, strongyloidiasis - 200 mg / day for 3 days.

In some cases, severe helminthic infestations the drug is prescribed to children aged 1-2 years, there are practically no adverse reactions in patients at this age.

Albendazole has many analogues that have a similar composition and therapeutic effect with it.

Albendazole or mebendazole - which is more effective

Albendazole or Nemozol - which is better

Albendazole or Pyrantel - which is better

Pirantel contains albendazole as the main ingredient, but the drug has practically no contraindications. It can be taken during pregnancy and while breastfeeding.

Albendazole or Vermox - which is better

Contraindications

The medicine can not be taken with individual intolerance to the main substance, with damage to the retina, during lactation. It is prescribed with caution for severe pathologies of the liver and kidneys, problems of hematopoiesis, cysticercosis.

Important! Albendazole and alcohol should not be taken together - active substance the drug enters into an active reaction with ethanol, which leads to severe intoxication.

Side effects

The instructions for use for humans indicate that when taking the drug, there are rarely adverse reactions subject to the recommended dosages.

During therapy, sometimes observed:

• migraine, dizziness attacks;
• pain in the epigastric region, nausea;
• disorders in the work of the kidneys;
• allergic manifestations in the form of itching, rashes;
• increase in arterial and intracranial pressure, temperature indicators;
• temporary alopecia.

With an overdose, the intensity of manifestations of negative reactions increases, it is necessary to do a gastric lavage, take enterosorbents.

Important! While taking the drug, it is necessary to regularly do a blood test, since the level of platelets and leukocytes may decrease during treatment.

A sign of helminthiasis is causeless weight loss, cramps and pain in abdominal cavity, itchy in anus. If you find such symptoms, you should contact your local doctor, who will give qualified recommendations. As a rule, after examinations and diagnosis, patients are prescribed Albendazole 10. Consider the principle of action, indications and methods of treatment with this unique medicine.

The principle of action of Albendazole

This drug was developed in the 70s of the last century. Albendazole for humans has been successfully used to combat helminths in all countries and continents. The medicine is taken orally in the form of tablets, suspension and powder in capsules. This allows you to freely treat people of any gender, age and temperament for worms. Chewable tablets have been developed for children and patients with swallowing problems.

According to the results of clinical studies, in people who are treated with Albendazole 10, the destruction of helminths by 90-95% is observed. Already after the first stage of treatment, a person experiences significant relief and improvement in well-being. Parents are especially happy when their child is on the mend after depletion of the body by helminths.

Indications for the use of the drug

The medicine is intended for the treatment of helminthiasis in patients aged 5-60 years. For children and people of advanced age, Albendazole suspension or chewable tablets are prescribed only after medical consultations and testing of patients for tolerability of the active components of the drug.

Albendazole, analogues of this drug are used to treat such diseases:

Albendazole 10 is guaranteed to destroy such varieties of helminths as Giardia, Ascaris, bull tapeworm, unilocular and alveolar echinococci, amoeba and schistosomes. The use of this tool all over the world is justified by its high performance with minimal side effects.

Treatment of helminthiases with Albendazole

The drug is prescribed on the basis of the recommendations of the attending physician. In some countries, it is sold by prescription only. This is justified by the rather strong toxic effect that Albendazole has, the components that make up its composition can cause quite a lot of harm to the human body in case of an overdose or improper treatment.

On the basis of the conducted studies, a course of treatment is prescribed. It includes prescriptions such as the type of drug, a single dose of its intake, frequency and duration.

As a rule, the treatment of various types of helminthiasis is prescribed as follows:

1. Filariasis - 2 times a day, 400 mg. As a rule, the course of treatment lasts at least 10 days.
2. Ascariasis - the medicine is taken 1 time per day during lunch. A single dose is 0.4 g. The treatment takes place in 2 stages: a week of taking the medicine, a 2-week break and again a week of taking it.
3. Echinococcosis - the drug is taken twice a day for a month. A single dose is calculated at 15 mg of the drug per 1 kg of the patient's weight. Treatment is carried out in 3 stages with intervals of 15 days.
4. Cysticercosis - the medicine is taken twice a day for 10-30 days. A single dose for adults is 400 mg, for children - based on 1 kg of weight 15 mg of the drug.
5. Toxocariasis - the course of treatment lasts 20 days. The patient should take 400 mg twice a day.
6. Strongyloidiasis - medication is taken 2-3 times a day, 400 mg each. Depending on the clinical case, the course of treatment lasts 10-20 days.
7. Giardiasis - patients are prescribed 200 mg of the drug twice a day. The course of treatment is designed for 10-15 days.

In each case, a single dose, the frequency of taking the medicine, the time of treatment and its frequency are calculated individually. Self-diagnosis and self-treatment are unacceptable, as serious harm can be done.

Contraindications to the use of the drug

Despite the fact that Albendazole has established itself as a safe agent for effective treatment helminthiasis in all its manifestations, it should be treated with extreme caution.

1. Persons who are diagnosed with hypersensitivity to individual components of the drug. You can find this out by medical card or by conducting post-diagnosis follow-up tests.
2. During pregnancy and after childbirth, if the baby is breastfed. The medicine can harm the developing organism.
3. Small children under the age of two. The drug is prescribed only if there are no contraindications for severe invasions.
4. Elderly people with disorders in the digestive and cardiovascular systems.
5. Patients diagnosed with renal or liver failure, cirrhosis of the liver, gastric and duodenal ulcers.
6. Women who plan conception and pregnancy. The drug must be stopped no later than 3 months before conception, so that it is completely eliminated from the body.

Even conditionally healthy people it is necessary to take a break between the stages of treatment to allow the body to recover. This interval can last from 10 days to a month, depending on the condition of the patient.

Side effects of Albendazole

As a rule, the drug does not affect the well-being of a person, his work internal organs and the state of the central nervous system. However, in the history of clinical studies, there have been some health complications caused by taking Albendazole.

This medicine may cause these side effects:

1. General. The patient's state of health worsens, sleep disappears, dizziness is observed. Because of this, the person becomes nervous and irritable. In rare cases, patients have experienced partial hair loss.
2. Violation of the digestive system. It manifests itself in sharp pains in the abdomen, deterioration in the functionality of the liver and kidneys. Sometimes there is constipation or diarrhea. Quite often, nausea occurs, accompanied by vomiting, in the mass of which there are remains of helminths. Urine acquires a dark color, uncharacteristic of the secretions of a healthy person.
3. Disorders of the nervous system. This is expressed in short-term convulsions that affect the upper and lower limbs. Some patients showed yellowing skin And eyeballs accompanied by visual impairment.

During the treatment period, it is worth giving up long trips and driving a car so as not to get into an unpleasant situation due to disorders in the body.

Possible Complications

Complications dangerous to the health of the patient are recorded extremely rarely. As a rule, they occur when the drug is taken for a long time or the permissible dose is exceeded.

In such cases, the patient has:

1. Violation of the function of hematopoiesis. This leads to a significant increase in blood pressure, impaired speech, coordination of movements and prolonged bouts of insanity. Such phenomena are extremely dangerous, as they can happen at the most inopportune moment, leading to injury or death.
2. Problems in the liver. When taking a large dose of the drug, non-infectious hepatitis develops. This is evidenced by symptoms such as discoloration of feces, staining of the skin, saliva and sweat in an orange color.

At the first sign of complications, you should immediately contact your doctor. He will provide the first medical care and prescribe drugs to relieve toxicosis. In order to reduce the effects of taking Albendazole and increase its effectiveness, patients are prescribed Phenytoin, Phenobarbital, Cimetidine or Carbamazepine.

Analogues of the drug and release form

Since Albendazole preparations are produced in many countries and include various chemical and natural additives, its name may sound different.

In the network of pharmacies, its trade names are as follows:

• Helmadol;
• Wormil;
• Nemozol;
• Aldazole;
• Sanoxal;
• Zentel.

All these funds basically have one active substance and practically do not differ in the spectrum of action.

Albendazole is produced in the form of a suspension, which must be taken in doses. One spoon has divisions in order to measure the medicine to incapacitated adults or young children. Tablets and capsules contain 200 mg and 400 mg of the medicinal substance. This approach makes it possible to satisfy all the needs of the population as much as possible when choosing a medicine of the desired form and dosage.

Comments

Megan92 () 2 weeks ago

Daria () 2 weeks ago

Previously, they poisoned themselves with chemicals such as Nemozoda, Vermox. I had terrible side effects: nausea, impaired stool, my mouth was covered, as with dysbacteriosis. Now we are taking TOXIMIN, it is much easier to tolerate, I would even say without any side effects. good remedy

P.S. Only now I myself am from the city and did not find it in pharmacies, I ordered it via the Internet.

Megan92 () 13 days ago

Daria () 12 days ago

Megan92, I already indicated) Here I am attaching again - TOXIMIN official website

Rita 10 days ago

Isn't this a divorce? Why sell online?

Yulek26 (Tver) 10 days ago

Rita, you seem to have fallen from the moon. In pharmacies - grabbers and even want to make money on it! And what kind of divorce can there be if payment after receipt and one package can be received free of charge? For example, I ordered this TOXIMIN once - the courier brought me, I checked everything, looked and only then paid. At the post office - the same thing, there is also a payment upon receipt. And now everything is sold on the Internet - from clothes and shoes to appliances and furniture.

Rita 10 days ago

Sorry, I didn't notice at first the information about the cash on delivery. Then everything is in order for sure, if the payment is upon receipt.

Elena (SPB) 8 days ago

I read the reviews and realized that I should take it) I'll go to place an order.

Dima () A week ago

Also ordered. They promised to deliver within a week (), what will we wait

In this article, we will look at why doctors prescribe Albendazole, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Albendazole can be read in the comments.

Indications for use

Nemozol is prescribed when a person has one or more diseases confirmed:

• ascariasis;
• enterobiasis;
• necatorosis;
• strongyloidiasis;
• toxocariasis;
• echinococcosis;
• hookworm;
• trichinosis;
• taeniasis;
• mixed invasions.

Nemozol can be used alone or as part of a complex treatment.

pharmachologic effect

Albendazole is effective at all stages of development and reproduction of helminths, the drug inevitably causes the death of adults, does not allow larvae to develop, blocks the reproduction function.

When taken orally, the components of the drug are distributed throughout the body - in laboratory tests, the drug is detected in urine, bile, cerebrospinal fluid, and is found in the liver and cysts. Effectively penetrates through the membrane of cysts different types helminths.

Fatty food products several times increases the absorption of the drug in the human body. The maximum concentration of active medicinal substances can be observed 2-4 hours after taking the remedy. The withdrawal time of the drug is about 8-11 hours.

Instructions for use

According to the instructions for use, Nemozol is taken orally, during or after a meal, the tablets are washed down with water. It is recommended to receive simultaneous therapy with albendazole by all persons living in the same room.

The dosage is prescribed individually, depending on the type of helminthiasis and the patient's body weight.

• For the treatment of giardiasis, 0.4 g is prescribed once a day for 3 days.
• With ascariasis, trichuriasis, enterobiasis and ankylostomiasis, patients weighing more than 20 kg take 400 mg of the drug once. If necessary, the reception is repeated after 2-3 weeks. For children weighing up to 20 kg, 200 mg of the drug is sufficient.
• If a person suffers from neurocysticercosis, then 15 mg of medication per day should be calculated per 1 kg of body weight. This dosage is divided into 2 times. It is necessary to be treated in this way for a month. If echinococcosis has been diagnosed, then the dosage does not change. But here it is necessary to carry out 3 courses of treatment, which last for 28 days. Between them there should be breaks of 14 days.
• Toxocariasis: adults and children over 14 years of age weighing more than 60 kg Nemozol is used in a single dose of 400 mg; with a body weight of less than 60 kg - 200 mg, for children under 14 years of age, the dose is set at the rate of 10 mg / kg; the multiplicity of reception 2 times / day, the duration of therapy is 7-14 days. In case of toxocara invasion: persons over 14 years old with a body weight> 60 kg Nemozol is used in an amount of 0.4 g; with body weight
• Strongyloidiasis. For strongyloidiasis, 400 mg of the drug is used twice a day for a week. With trichinosis, the same dosage is used, only the course of therapy is from 8 to 14 days. For the treatment of trichuriasis, 400 mg is prescribed once a day for 3 days.

The maximum daily dosage is 800 mg.

During treatment, you do not need to follow any special diet or take laxatives.

Contraindications

Albendazole is not prescribed for:

• helminthiases in children under 2 years of age;
• hypersensitivity to albendazole;
• pregnancy;
• lactation.

With caution when:

• pathologies of the retina against the background of cysticercosis;
• cirrhosis of the liver;
• oppression of bone marrow hematopoiesis.

Side effects

Albendazole for worms can cause a number of side effects:

• allergies - skin rash, itching in these places;
• human nervous system - dizziness and recurrent headaches, characteristic meningeal symptoms;
• organs of the gastrointestinal tract - nausea and the corresponding urge to vomit, elevated indicators of the activity of "liver" enzymes-transaminases;
• hematopoietic system - a decrease in the number of leukocytes or platelets, agranulocytosis, granulocytopenia, and pancytopenia;
• other phenomena - increased arterial pressure, hyperthermia, malfunctioning of the kidneys, alopecia, in rare cases, acute renal failure.

Self-medication with Albendazole is the most common cause the development of such effects.

Analogues

Trade names of "Albendazole" are "Nemozol", "Zentel", "Gelmadol", "Sanoksal", "Aldazol", "Vormil". All these drugs are synonyms, i.e. contain the same active ingredient.

During the application of Albendazole, about 5% is absorbed from gastrointestinal tract. Taking the medicine in combination with fatty foods reduces the absorption capacity. The main component is metabolized in the liver and excreted from the body within 5-8 hours. Holding laboratory research confirmed the absence of a carcinogenic effect on the human body.

Produced form of the drug: white tablets containing the active substance in the amount of 0.4 mg. One package contains 3 tablets in a blister. In the form of a solution for the preparation of a suspension, the drug is not produced.

Appointments, contraindications, side effects of Albendazole

Since Albendazole has extended indications for use, all contraindications of the drug must also be taken into account:

While taking the drug, side effects may occur in the form of:

To avoid the occurrence of side effects, you should take the drug only as directed by your doctor and strictly follow the prescribed dosage.

Instructions for use Albendazole

Albendazole is administered orally after meals. Tablets are swallowed without chewing and washed down with the necessary amount of water.

An overdose of the drug causes increased side effects and intoxication of the body. Symptomatic treatment, intake of enterosorbents, rapid cleansing of the stomach are recommended.

You can buy Albendazole in a pharmacy only with a prescription. The shelf life of the drug is 3 years. After the expiration of the time, the use of an expired drug is strictly prohibited! Storage conditions at a temperature of 20–25 degrees in a dry, cool place protected from light, out of the reach of children.

Additional indications and analogues of Albendazole

Drugs such as Praziquantel, Dexamethasone, Cimetidine significantly increase the amount of Albendazole in the blood.

The combination of theophylline with the main drug does not cause negative side effects. Long-term use of Albendazole involves constant monitoring of liver function. At the onset of leukopenia, the medication should be stopped immediately.

During the use of the drug, a woman of childbearing age is prohibited from becoming pregnant, since active substance adversely affect the development of the embryo. It is best to take contraceptive measures at this time.

Driving a car and operating other devices is quite commensurate with the use of the drug, since no negative side effects of the drug have been studied.

The average price of Albendazole in Russia is relatively low and amounts to 170-250 rubles. The drug has a large list of contraindications and side effects, so it is not suitable for all categories of the population. In this case, you can choose a worthy analogue of the drug, similar in general spectrum of action and pharmacological group. Some of the main synonyms of Albendazole are presented in the list below.

The selection of a suitable Albendazole analogue should be determined by the attending physician, who is a qualified specialist in this field. Self-replacement of the drug may threaten the appearance of undesirable side effects of the drug and the loss of its effectiveness!