Description of tablets egilok. Egilok is an effective antihypertensive drug. At what pressure to take the medicine

Beta-blockers are multidisciplinary - they are used not only to reduce blood pressure but also in improving the overall functional state of the heart and blood vessels. A modern drug is Egilok, which is excellent for a number of heart diseases.

What kind of medicine is Egilok?

Egilok tablets are produced by Egis-Rus (Hungary) and are included in pharmacological group beta-blockers cost 140 rubles for 30 pieces with a dosage of 100 mg. The composition contains metoprolol - a cardioselective beta-blocker - in the form of metoprolol tartrate (made on the basis of tartaric acid salts). Also on sale you can find tablets with a dosage of 25 and 50 mg in packs of 30 and 60 pieces.

List excipients looks like that:

Active substance normalizes the work of the sympathetic system, which suppresses the force of its effect on the function of the heart. Metoprolol also fights arrhythmia by quickly lowering the heart rate and cardiac output. Against the background of such effects, blood pressure normalizes or decreases, and in any position of the patient and for a significant period. This is due not to a sharp, but a slow decrease in vascular resistance. At the same time, during the course of taking Egilok, the weight and volume of the left ventricle decrease, and its work is optimized. Other positive effects medicines:

Metoprolol gives fewer side effects than non-selective beta-blockers, has virtually no effect on insulin production, carbohydrate metabolism, and does not provoke attacks of a sudden decrease in sugar. After 1-2 years of taking the drug also regulates cholesterol levels.

Indications and contraindications

Egilok is widely used in different forms ah hypertension. It may serve as the sole drug of choice or be involved in complex therapy hypertension. Also, an indication for the use of Egilok tablets can be considered angina against the background of coronary artery disease. The medicine reduces the frequency of attacks, reduces their severity, treats asymptomatic forms of pathology, and optimizes performance.

With a heart attack, the remedy has also found application - it seriously reduces the mortality rate, since it prevents ventricular fibrillation.

Egilok is taken almost immediately after a heart attack in complex treatment, also shown in late stage acute violation of the coronary circulation.

The remedy shows especially good results in patients diabetes(with a heart attack compared with other drugs). In addition, the early start of taking the pills reduces the risk of a second heart attack. Other indications of Egilok:

The medicine has a number of important contraindications. It should not be drunk with allergies, intolerance to metoprolol or all beta-blockers, with AV blockades of 2-3 degrees, reduced rhythm (less than 50 beats), weakness of the pacemaker. The drug is also prohibited in such cases:

With caution, therapy is carried out for diabetes mellitus and any type of bronchial asthma, COPD, myasthenia gravis, and other types of heart blockade. Also, a strict setting of how much and how to drink the remedy, regular examinations will be needed for patients with Raynaud's syndrome, renal failure, psoriasis. The use of Egilok during pregnancy is possible for health reasons, but, in general, is not recommended. This is associated with the risk of respiratory depression, bradycardia in the newborn. Also, within 2-3 days from the moment of birth, in children whose mothers received Egilok treatment, sugar and pressure indicators are assessed.

Egilok's instructions

According to the annotation, the tablets should be taken orally, the order of therapy does not depend on food. A pill with any dosage can be divided in half, it has a convenient risk. Initially, the minimum dosage is prescribed, which is then left the same or increased.

It is important to select the dose gradually to prevent a strong decrease in pressure and bradycardia.

Take no more than 200 mg of Egilok per day, or 2 tablets / 100 mg. Usually, with hypertension of the initial, middle stage, 25-50 mg in the morning and evening is enough. In a severe form of the disease, the dose is increased to 100 mg twice / day, or other drugs are added at another time or together with Egilok. Other recommendations for therapy:

With advanced renal dysfunction, the drug is not taken, in other cases of impaired renal function, the dose is normal. In case of liver damage, dose adjustment is also not needed, except in situations of severe liver failure or recent operations on the vessels of the liver.

Side effects

The drug is well tolerated by patients, but of moderate severity side effects quite common at the beginning of therapy. Some negative phenomena are observed further, or increase in severity, which forces Egilok to be replaced with another medicine.

Often tablets cause dizziness and a feeling of increased fatigue, less often - headaches.

The drug can reduce concentration, cause drowsiness during the day and insomnia at night. It can provoke convulsions, depression, hyperexcitability. The heart may respond with bradycardia and the development of hypotension, fainting, cold hands and feet, worsening of heart blockades, and arrhythmias are possible. Isolated cases of gangrene in patients with impaired peripheral circulation have been described.

On the part of the gastrointestinal tract, constipation, nausea, and dry mouth are often observed. Perhaps the development of various forms of allergic reactions, hair loss, exacerbation of psoriasis. Many patients experience cough, shortness of breath, and dry eyes.

Important Notes

When taking Egilok, it is important to regularly measure blood pressure, heart rate, and in case of diabetes, blood sugar. The dose of insulin, hypoglycemic agents for the period of treatment may increase. Other instructions for proper therapy:

When wearing contact lenses Dry eyes can cause discomfort. It is necessary to apply drops for additional moistening of the mucous membrane. Egilok is able to mask tachycardia caused by other diseases. Before any ongoing operation, you need to warn the doctor about taking Egilok, since the selection of special forms of anesthesia will be required.

Analogues and interaction

Among the analogues there are other drugs based on metoprolol, but some drugs include other components, so you cannot change the prescribed remedy yourself:

Egilok mutually enhances the effect of other antihypertensive drugs. More pronounced side effects develop while taking calcium channel blockers. Caution should be observed when combined with antiarrhythmics - there is a risk of developing bradycardia, heart blockade.

Defeat thyroid gland may affect performance of cardio-vascular system. In this case, the drug Egilok is needed, which minimizes the consequences of negative reactions.

INN

International generic name- Metoprolol.

Name on Latin- Egilok.

Release form composition and packaging

The medication includes the following additional substances:

• sodium carboxymethyl starch;
• povidone;
• colloidal silicon dioxide;
• magnesium stearate;

A medicine is also produced in the form of Egilok Retard, which has a similar active substance.

pharmachologic effect

The drug belongs to selective beta-blockers and has the necessary actions to eliminate the symptoms of heart disease:

• antianginal;
• antiarrhythmic;
• hypotensive.

The drug reduces myocardial oxygen demand, quickly reduces heart rate and cardiac output, reduces pressure, which prevents the development of seizures due to heart pathologies.

What is Egilok for?

Indications for the use of the drug are:

• angina;
• atrial fibrillation;
• prevention of migraine attacks;
• violations of cardiac activity;
• supraventricular tachycardia;
• increased production of thyroid hormones (hyperthyroidism);
• prevention repeated heart attacks myocardial and stroke;
• the threat of heart failure;
• bradycardia with extrasystoles of the ventricles.

At what pressure to take

How to take Egilok

The medicine is used for oral administration. It is allowed to use the drug on an empty stomach, but it is more often recommended to take the medication during a meal. The medicine can be washed down with a small amount of liquid.

The number of doses of the medication - 2 times a day, i.e. after waking up and in the evening.

With arrhythmia

During arrhythmia, the drug is prescribed in an amount of 50-100 mg per day. The exact dose is selected by the doctor. In severe cases, the dosage is increased.

With hyperthyroidism

The amount of medication for the treatment of hyperthyroidism is 50-100 mg per day. If necessary, the dose can be increased to 200 mg.

Side effects of Egilok

During the use of the drug, adverse reactions are possible, which will lead to:

• deterioration in concentration;
• low pressure;
• increased concentration of potassium in the blood;
• hyperglycemia;
• headache;
• shortness of breath, including during physical activity;
• convulsions;
• drowsiness;
• vomiting
• the feeling of cold felt lower limbs;
• stomach ache;
• dry mouth;
• increased sweating;
• baldness (rarely);
• nettle fever;
• bronchospasm in the presence of asthma in a patient;
• hypersensitivity to sunbeams;
• tinnitus;
• increased body weight;
• visual impairment;
• unpleasant aftertaste.

Contraindications for use

It is forbidden to prescribe a medication if the patient has the following disorders and conditions:

• problems with peripheral circulation (in severe form);
• sinus type bradycardia;
• high sensitivity to the composition of the drug and to other drugs belonging to the group of beta-blockers;
• development of heart failure at the decompensated stage;
• pheochromocytoma, which did not arise as a result of taking alpha-blockers;
• bronchial asthma, characterized by a severe course;
• atrioventricular blockade 2 and 3 degrees;
• sick sinus syndrome;
• chronic obstructive pulmonary disease;
• sinoatrial blockade;
• state of shock of cardiogenic origin.

special instructions

It should be noted that the agent may mask the onset of hypoglycemic attacks in diabetic patients.

During the period of therapy, alcohol should be avoided.

Use during pregnancy and lactation

It is not recommended to take Egilok while breastfeeding. During pregnancy, the drug is prescribed with caution and only in cases where the benefits outweigh the harm. It's connected with high risk the development of complications in a child: hypoglycemia, low blood pressure and heart rate disorders.

Application for violations of kidney function

If the patient has kidney failure the drug is used with caution. In other cases, it is not necessary to change the dosage.

Can children take

The drug is contraindicated for the treatment of patients under 18 years of age. The reason is the lack of reliable information about the safety of the drug in childhood.

Overdose

Taking the medicine in the wrong doses leads to the following signs of an overdose:

• bronchospasm;
• loss of consciousness;
• vomiting and nausea;
• sinus bradycardia;
• atrioventricular blockade;
• a strong decrease in pressure;
• shallow breathing;
• bluing of the skin.

It is necessary to take the patient to the hospital, where he will receive medical care.

drug interaction

Taking Egilok along with other medicines leads to similar features:

• barbiturates, Rifampicin - the effectiveness of the active ingredient worsens;
• Paroxetine, Hydralazine, Sertraline, Cimetidine - the properties of Egilok increase;
• muscle relaxants of the curare-like type - neuromuscular blockade increases;
• estrogens and NSAIDs - blood pressure rises due to a deterioration in the antihypertensive effect;
• Ergotamine - increases the vasoconstrictive effect;
• tricyclic antidepressants, tranquilizers, sleeping pills, neuroleptics - the likelihood of hypotension increases;
• medicines to lower blood pressure - increases the risk of developing bradycardia or hypotension;
• Verapamil - increases the likelihood of cardiac arrest.

Manufacturer

The drug is produced by the Hungarian company Egis.

Terms and conditions of storage

The medication should be stored in a dark place at a temperature not exceeding +25°C. Shelf life - 5 years.

Terms of dispensing from pharmacies

A prescription is required to purchase Egilok.

Price

Price medicinal product- 110-180 rubles.

Analogues

Analogues of Egilok are the following drugs:

1. Metoprolol is a cardioselective beta-blocker.
2. Metozok. It has antiarrhythmic and antianginal effects.
3. Biol. Selective blocker that is not characterized by sympathomimetic activity
4. Non-ticket. Contains nebivolol hydrochloride. It has a hypotensive effect.
5. Concor. Substitute for Egilok, contains bisoprolol. It does not have a strong inotropic effect.
6. Anaprilin is a non-selective beta-blocker, which is aimed at reducing the flow of calcium ions into cells.
7. Metocard is a drug with an antiarrhythmic effect.
8. Nebilong is a beta1-blocker used to lower blood pressure.
9. Betalok ZOK. The active substance is metoprolol succinate. The drug is characterized by an antianginal effect, as a result of which the myocardial oxygen demand decreases.

Egilok - a drug (tablets), belongs to the group of beta-blockers. In the instructions for use, the following features of the drug are distinguished:

• Sold by prescription only
• During pregnancy: with caution
• When breastfeeding: contraindicated
• In childhood: contraindicated
• With impaired liver function: with caution
• In case of impaired renal function: with caution
• In old age: with caution

Package

Compound

Tablets of 25, 50, 100, 200 mg.

One tablet of Egilok, Egilok Retard contains 25, 50, 100 mg of the active substance (metoprolol tartrate), respectively.

One tablet of Egilok C, the active substance (metoprolol succinate), accounts for 23.75, 47.5, 95, 190 mg, respectively.

Excipients for Egilok, Egilok Retard: povidone, sodium carboxymethyl starch, magnesium stearate, microcrystalline cellulose, colloidal anhydrous silicon dioxide.

Excipients for Egilok C: ethyl cellulose, microcrystalline cellulose, corn starch, metal cellulose, glycerol, magnesium stearate.

Release form

Packed in a cardboard box of 1, 2 and 3 blisters, 10 pcs. in each for 25mg, 50mg, 100mg, 200mg tablets.

Packed in a dark glass bottle: 30 and 60 pcs. for 25 mg, 50 mg and 100 mg tablets.

Round biconvex tablets of white or almost white color. Without smell. Volume: 25 mg, 50 mg, 100 mg.

• Egilok 25 mg tablet has a cross-shaped dividing line with a double bevel on one side, engraving E435 on the other side.
• On the Egilok 50 mg tablet, on one side of the risk, on the other side, engraving E434.
• On the Egilok 100 mg tablet, on one side of the risk, on the other side, engraving E432.

Egilok Retard

White biconvex tablets of round shape, scored on both sides. Volume 50 mg and 100 mg.

Biconvex tablets in white film shell oval shape. On both sides of the risk. Volume: 25 mg, 50 mg, 100 mg, 200 mg.

pharmachologic effect

Develops hypotensive, antiarrhythmic, antianginal and beta1-adrenergic blocking stimulation. Causes a rapid decrease in contractions in the heart muscle.

In the case of sinus tachycardia against the background of hyperthyroidism and functional problems with the heart, as well as atrial fibrillation and supraventricular tachycardia, the drug can significantly slow down the heart rate until the sinus rhythm is restored.

Unlike non-selective beta-blockers, the effect of metoprolol on carbohydrate metabolism and insulin production is less significant.

Pharmacodynamics and pharmacokinetics

The drug has high speed absorption in the gastrointestinal tract. Within 1.5-2 hours after ingestion, Cmax in blood plasma is reached. Under the influence of the active substance, the increased activity of the sympathetic system in relation to the heart is suppressed. From what tablets Egilok with regular use cause a decrease in cholesterol levels in the blood serum. The bioavailability of the drug increases by 30-40% if metoprolol is taken with food.

The impaired function of the kidneys and liver has practically no effect on the excretion and absorption of the active substance. However, with severe liver dysfunction (cirrhosis, portocaval shunt), bioavailability increases significantly, and with chronic renal failure, the risk of unwanted side effects increases. In old age, the pharmacokinetics of the drug does not change significantly.

After use, the drug passes the full degree of absorbability. Egilok has a weak binding to proteins in the blood plasma (no more than 10%). The drug is excreted from the body mainly in the form of metabolites, only 5% is excreted by the kidneys.

Indications for use Egilok

• prophylactic prevention of migraine attacks;
• high blood pressure;
• impaired functional cardiac activity;
• angina;
• disturbed heart rhythm (supraventricular tachycardia and bradycardia with ventricular extrasystoles and atrial fibrillation);
• myocardial infarction.

Indications for the use of tablets also apply to people over 60 years of age.

Contraindications

• SSSU;
• cardiogenic shock;
• severe bradycardia (less than 50 beats per minute);
• lactation period;
• simultaneous reception of MAO inhibitors;
• age up to 18 years;
• hypersensitivity to the components of the drug in particular, or to beta-blockers in general;
• sinoatrial blockade;
• severely disturbed peripheral circulation;
• severe bronchial asthma;
• AV - blockade of 2 or 3 degrees.

Side effects

• In relation to the central nervous system: increased fatigue threshold (very often), headaches and dizziness (often); infrequently - convulsions, impaired attention, depression, increased heart failure, nightmares; rarely - nervous excitability, anxiety, sexual dysfunction, hallucinations, memory impairment.
• In relation to the sense organs (rare): blurred vision.
• Towards digestive system(rare): abdominal pain, diarrhea, constipation, dryness in the mucosal area in the mouth.
• Towards respiratory system: shortness of breath with physical exertion (often), rhinitis (rarely).
• Towards skin(uncommon): rash, increased sweating.

Instructions for use Egilok

Tablets are taken orally, washed down with a small amount of water. Reception is allowed both during meals (recommended), and on an empty stomach.

Instructions for Egilok Retard and Egilok: the dose is divided into two doses per day, morning and evening.

Instructions for Egilok C: take 1 time per day, in the morning.

How to take (the final dose size and number of doses) the medicine is determined by the doctor individually. Maximum dose 200 mg. With impaired renal function and with advanced age, redistribution of the volume of the drug consumed is not required.

• Heart failure with compensation: 25 mg per day.
• Hyperthyroidism: 50-200 mg per day.
• Arrhythmia: 50-200 mg per day.
• Angina pectoris: 50 mg per day.
• Migraine attacks (prevention): 100-200 mg per day.
• Tachycardia: 50-200 mg per day.
• Myocardial infarction (secondary prevention): 200 mg per day.

Overdose

Excessive and inconsistent with the doctor's use of the drug leads to an overdose, the most obvious symptom of which is a reaction from the cardiovascular system: slowing of the pulse, heart failure. In some cases, when using the medicine by persons under 18 years of age, it is also possible backlash from the side of the central nervous system: increased fatigue, the occurrence of convulsions, excessive sweating, the onset of fatigue.

General symptoms: apnea, impaired consciousness, tremor, bronchospasm, vomiting, hyperkalemia or hyperglycemia, worsening of renal activity, asystole, a marked decrease in blood pressure.

In case of an overdose, one or more of the above symptoms occur within 20-120 minutes, depending on the characteristics of the organism. A high concentration of metoprolol in the body, depending on the nature of the symptoms, is eliminated by gastric lavage, symptomatic therapy, the appointment of adsorbents, atropine sulfate, gluconate, dopamine, norepinephrine.

The use of the drug Egilok with other medications

List of prohibited drugs simultaneous use wide with Egilok. Therefore, it is necessary to combine this drug with third-party medicines with special care.

When mixed with verapamil, it can cause cardiac arrest.

When mixed with beta-blockers (estrogens, theophylline, indomethacin), the hypotensive property of metoprolol decreases.

When mixed with ethanol, the pumping effect on the central nervous system is enhanced.

When mixed with oral hypoglycemic drugs and insulin, the likelihood of hypoglycemia increases.

When mixed with barbiturates (pentobarbital), under the influence of enzyme induction, the metabolism of metoprolol is accelerated.

Terms of sale

Egilok is dispensed by prescription.

Storage conditions

Egilok, Egilok Retard is stored at a temperature of 15 to 25 degrees.

Egilok C is stored at temperatures up to 30 degrees.

Shelf life

Egilok Retard, Egilok: 5 years.

Egilok S: 3 years.

Egilok's analogs

The cardioselective blocker of β-adrenergic receptors (INN: Metoprolol) has analogues similar in their effect on the body. These include: Betaloc, Vasocardin, Corvitol, Lidaloc, Metozok, Metocard, Metolol, Emzok, Metoprolol. However, it should be understood that drug analogues cannot always fully replace the originally prescribed prescription. Therefore, when replacing a drug with a similar drug, be sure to consult a cardiologist.

Concor or Egilok - which is better?

The exact answer can be given only with an individual examination. However, in general, Concor has slightly fewer side effects compared to Egilok, and its use with a low pulse in more admissible. Egilok has a stronger drug effect compared to Concor.

Egilok and alcohol

The interaction of the drug with alcohol-containing substances leads to sharp decline blood pressure, which in turn can lead to cerebral hypoxia. So, possible: weakness, dizziness, loss of consciousness. In case of refusal medical care and with strong concentrations of metoprolol and alcohol in the body, energy resources in the brain are depleted, which can lead to tragic consequences.

Egilok during pregnancy and lactation

Due to the lack of comprehensive information on the conducted therapeutic studies regarding the effects of metoprolol on the embryo, it is allowed to include the drug during the treatment period only in one case, when the benefit to the pregnant patient is considered higher than the risk of harm to the fetus.

However, the drug is often used during pregnancy, but in no case in the first trimester and not during lactation and breastfeeding. The size of the dose and the frequency of taking are determined strictly individually. Among those who have tried the drug, there are reviews during pregnancy. As a rule, those women who followed the doctor's recommendations during the course of taking the medicine did not experience discomfort, but, on the contrary, their cardiovascular condition improved.

Reviews for Egilok

Given that the drug is one of the most popular drugs in its group, there are many responses, these are both doctors' reviews of Egilok Retard, and reviews from ordinary users who publish their opinions on the Internet. In order to find out reviews about pills, just visit the pharmacy forum. According to most, the drug can often cause temporary fatigue in the early stages of taking, but at the same time it fights well with a rapid pulse, quickly slowing it down. In addition, during the course, a slowdown in speed is noticed. motor reactions, in connection with which driving vehicle and the handling of potentially dangerous machinery must be handled with care.

Price for Egilok, where to buy

The average price for Egilok Retard, set in Moscow pharmacies: 215 and 275 rubles. for a pack of 30 pcs. 50 mg and 100 mg tablets.

The average price for Egilok in Moscow: 125 and 150 rubles. for 25 and 50 mg tablets in the amount of 60 pcs. in the bank.

The average price for Egilok S in Moscow: 175, 215, 275 rubles. for a pack of 30 pcs. 25, 50, 200 mg tablets.

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Antihypertensive drug is the drug "Egilok". What are these pills for? The drug has antiarrhythmic and antianginal properties. Tablets "Egilok" instructions for use suggests drinking with high blood pressure, migraine, angina pectoris.

Therapeutic properties

The medicine "Egilok", from which it helps to normalize pressure, is an effective beta-blocker. The drug creates an antianginal, antiarrhythmic, hypotensive effect. The active ingredient reduces arousal nervous system, quickly reduces the pressure and heart rate. Due to the smooth decrease in vascular resistance, a long-term hypotensive effect is observed.

Prolonged use of the drug in hypertension causes a decrease in the weight of the left ventricle of the heart. Doctors indicate that the drug reduces mortality among men with moderate high blood pressure. The drug "Egilok", from which angina attacks occur less often, reduces the need for myocardium in oxygen. With its systematic use, the amount of cholesterol in the blood decreases.

Composition and form of release

Produced in the form of white tablets. The active element of the drug "Egilok", from which these tablets are taken for violations of the heart, is metoprolol tartrate. Its amount reaches 25, 50 or 100 mg. A variety of "Egilok Retard" has a similar active ingredient in the amount of 50 or 100 mg. Auxiliary components are cellulose, silicon dioxide, magnesium stearate and other components.

Tablets "Egilok" 25, 50, 100 mg contain a dividing line on one side, and a numerical engraving on the back. The form "Egilok C" includes metoprolol succinate as an active element in the amount of 25-200 mg.

Indications for the use of the drug "Egilok"

What are these pills for? The tool is prescribed for:

• elevated blood pressure;
• for the prevention of migraine attacks;
• angina;
• violations of the heart;
• tachycardia;
• heart attack;
• atrial fibrillation;
• bradycardia and other cardiac arrhythmias.

Contraindications

Tablets "Egilok" instructions for use and doctors prohibit when:

• bradycardia;
• decompensation heart failure;
• during lactation;
• cardiogenic shock;
• hypersensitivity to the components of the drug "Egilok", from which these tablets can cause allergic reactions;
• sinoatrial and atrioventricular blockade of 2-3 degrees;
• pronounced reduced pressure;
• angiospastic angina.

Caution while taking the medication must be observed in children under 18 years of age and women during pregnancy. Physician supervision is required when prescribing tablets to patients with bronchial asthma, psoriasis, diabetes mellitus, myasthenia gravis, kidney or liver failure, thyrotoxicosis, metabolic acidosis, depression.

Medicine "Egilok": instructions for use

Tablets are taken orally with a sufficient volume of liquid, regardless of the meal. The dosage is set by a specialist depending on the indications and the individual characteristics of the patient. The daily volume of the drug should not exceed 200 mg. Tablets are drunk 2 times a day, dividing daily dose in half. Instructions for use "Egilok Retard" is similar.

Daily dosage for diseases

For the secondary prevention of a heart attack, take 200 mg. For the treatment of heart failure, 25 mg per day is prescribed. With hyperthyroidism, arrhythmia, tachycardia, the use of 50-200 mg is indicated. For angina pectoris, the dose is 50 mg per day. To prevent migraine attacks, you need to drink 100-200 mg per day.

Tablets "Egilok C" instruction prescribes to use 1 time per day, in the morning.

Side effect

The drug "Egilok", instructions and reviews indicate this, can cause negative reactions from various body systems. Adverse reactions include:

• palpitations, weakness, abdominal pain;
• nasal congestion, decreased libido;
• sinus bradycardia, fatigue;
• dry mouth, itchy skin;
• orthostatic hypotension, headache;
• constipation, shortness of breath; hives, weight gain;
• cardialgia, depression, nausea, vomiting;
• rash, exacerbation of psoriasis, arrhythmia;
• confusion, change in taste;
• leukopenia, increased sweating;
• back pain, asthenic syndrome;
• agranulocytosis, photodermatosis, hypoglycemia;
• hyperemia of the skin, memory impairment.

Analogues

The following analogues of Egilok have a similar effect on the body:

1. "Metoprolol".
2. "Lidalok".
3. "Metolol".
4. "Concor".
5. "Metocard".
6. "Betalok".
7. "Emsok".
8. "Corvitol".

"Concor" or "Egilok" - which is better?

Doctors respond as follows. Analogue "Concor" causes less adverse reactions, its use is more appropriate with a low pulse. The drug "Egilok" 100 mg and in other dosages is more strong remedy how it differs from Concor.

Price

In Moscow, St. Petersburg, you can buy "Egilok" 50 mg at a price of 137 rubles. In Ukraine, the medicine costs 55 hryvnias. In Minsk, it is offered for 6-13 bel. rubles. The price in Kazakhstan reaches 1245 tenge (Egilok 25 mg No. 60 tablets (pcs.) EGIS Pharmaceuticals, Ltd. (Hungary)).

Egilok is a drug from the therapeutic group of β-blockers. These drugs are among the main remedies for high blood pressure, diseases and heart rhythm disorders. The active substance is metoprolol. Below you can find information about the drug Egilok - instructions for use, recommendations for use and other important aspects of the use of the drug.

Composition, types, names, forms of drug release

Instructions for use of Egilok tablets and the information provided in it depends on the concentration of the active ingredient:

• 25 mg;
• 50 mg;
• 100 mg;
• 200 mg.

Egiloc is a sustained release tablet.

medicinal substance

Each tablet contains 25 mg, 50 mg or 100 mg of the active ingredient metoprolol.

Additional substances

The tablets also contain cellulose, colloidal silica, povidone, magnesium stearate.

Egilok - recipe

Egilok is available in pharmacies by prescription.

Therapeutic effect of the drug

Metoprolol blocks the β-receptors of stress hormones (adrenaline) in the body, suppressing the adverse effect of the organ response to stress. High blood pressure decreases, heart rate and pulse slow down, and the risk of heart rhythm disorders decreases. Metoprolol is one of the cardioselective β-blockers. This means that its maximum effect is on the β-receptors of the heart.

Indications for the use of the drug

According to the instructions for the use of Egilok, the drug is prescribed for adults and children.

adults

Egilok tablets for pressure are used in the treatment of the following conditions:

• high pressure;
• chest pain due to insufficient heart rate (angina pectoris);
• arrhythmia;
• stabilized heart failure characteristic symptoms(shortness of breath, swollen ankles);
• in complex therapy is prescribed for the treatment of heart failure;
• increased heart rate caused by non-organic (functional) heart failure.

• subsequent heart attacks or heart damage after a heart attack;
• migraine.

Children

Admission instructions

The instructions for use of Egilok (at what pressure, dosage of the drug) indicate the differences between the use of adult patients and the pediatric population.

Use by children and teenagers

Always give Egiloc to children and adolescents at the dosage and for as long as directed by the doctor. How is Egilok taken by children, at what pressure? Instructions for use recommends a drug for children with high blood pressure (because the drug causes a decrease in performance) for children over 6 years old; the dose depends on the weight of the child.

Important! The dosage and duration of treatment is determined by the doctor!

The usual initial dosage is 0.5 mg/kg of body weight 1 time per day, but not more than 50 mg per day. The physician may increase the dosage to 2 mg/kg body weight, depending on the response of blood pressure to treatment. There are no data on the intake of more than 200 mg daily in children and adolescents.

Use by adults

The difference in the dosage of the drug in adults depends on the disease. Despite the fact that the instructions for the use of Egilok for the elderly (at what pressure it can be taken, how to use it) does not indicate the need to adjust the dose, as in the case of all drugs, an elderly person needs to control the intake. You should not take the drug constantly, breaks are needed during treatment. Cases of addiction have not been registered, but cardiologists warn that with constant use, Egilok ceases to help lower blood pressure and cope with heart problems.

Hypertonic disease

47.5 mg 1 time per day. If necessary, the dose can be increased to 95-190 mg 1 time per day.

Ischemia

95-190 mg 1 time per day.

Functional tachyarrhythmia

95-190 mg 1 time per day.

Extrasystole, tachycardia

190 mg 1 time per day.

Stable exertional angina

95 mg 1 time per day. If necessary, the dose can be increased to 190 mg 1 time per day.

Prevention of migraine attacks

95-190 mg 1 time per day.

Hyperthyroidism

Always follow your doctor's instructions.

General application rules

Always take this drug as directed by your doctor. In the absence of confidence in the correct application, it is good to consult a specialist.

Take Egilok 1 time per day in the morning with a glass of water. Swallow the medicine whole or in halves. Don't chew.

special instructions

Tell your doctor before using Egilok in the following cases:

• Asthma.
• Prinzmetal's angina (chest discomfort usually occurs at night).
• Diabetes mellitus (hypoglycemia may be masked by this medicine).
• Pheochromocytoma (high blood pressure caused by a rare tumor of the adrenal medulla).
• Taking medication to reduce allergic reaction. Egilok can increase hypersensitivity to allergen substances, which can lead to an increase in the severity of the allergic reaction.
• Increased thyroid function (symptoms - increased heart rate, sweating, trembling, restlessness, increased appetite, weight loss - may be masked by medication).
• Psoriasis (skin disease).
• Circulatory problems - fingers or toes may tingle or turn blue.
• Heart block.
• Heart failure + one of the following:

1. A heart attack or angina attack in the last month.
2. Decreased kidney or liver function.
3. Age less than 40 or more than 80 years.
4. Diseases of the heart valve.
5. Enlarged heart muscle.
6. Postponed heart surgery in the last 4 months.

Important! If you need to use anesthesia, tell your doctor that you are taking metoprolol!

Treatment during pregnancy and lactation

If you are pregnant, breastfeeding, planning to become pregnant, talk to your doctor before taking this medicine. Egilok is not recommended for use during pregnancy and lactation.

Compatibility with other drugs

Before taking Egilok, tell your doctor about any medicines you are taking, have taken or may take.

The following agents may increase the antihypertensive effect:

• Cimetidine (treatment of ulcers);
• Hydralazine and Clonidine (antihypertensive agents);
• Terbinafine (elimination of fungal infections);
• Paroxetine, Fluoxetine, Sertraline (for depression);
• Hydroxychloroquine (malaria treatment);
• Chlorpromazine, Triflupromazine, Chlorprothixene (antipsychotic medicines);
• amiodarone, quinidine, propafenone (treatment for irregular heart rhythm);
• diphenhydramine (antihistamine);
• Celecoxib (pain relief).

The following medicines may reduce the antihypertensive effect:

• indomethacin (pain relief);
• Rifampicin (antibiotic).

Other medicines that can also affect the action of metoprolol:

• other β-blockers;
• adrenaline, norepinephrine, other sympathomimetics;
• antidiabetic agents - symptoms of hypoglycemia can be masked;
• Lidocaine;
• Reserpine, α-methyldop, Guanfacine, cardiac glycosides.

Compatibility with ACE inhibitors is allowed. Egilok can be combined with Enalapril and other drugs in this group. A combination with magnesium preparations (Panangin), angiotensin receptor blockers () is also possible.

Influence on the ability to drive vehicles and mechanisms

Egilok can cause fatigue, dizziness. Before driving a car or operating machinery, make sure that you are not under the influence of the drug.

Important! Combination with alcohol is not allowed!

Overdose

If you accidentally take a higher dose than prescribed, contact your doctor immediately! Signs of an overdose include:

• low blood pressure (fatigue, dizziness);
• slow pulse;
• irregular heart rhythm;
• heart failure;
• dyspnea;
• deep unconsciousness;
• nausea;
• vomit;
• blue skin color.

A decrease in heart rate can cause bradycardia with collapse or worsening of heart failure.

Side effects of the drug

Like all medicines, Egilok can cause side effects, although not everybody gets them.

Stop taking Egilok, call your doctor if you experience symptoms of an allergic reaction:

• itchy rash;
• redness;
• swelling of the face, lips, tongue, throat;
• difficulty breathing, swallowing.

These are very serious, but rare negative consequences. When they occur, the patient may require urgent specialized care or hospitalization. It is necessary to replace Egilok with another agent.

Side effects are divided depending on the frequency of occurrence.

Very common (> 1 person in 10):

• feeling of weakness when standing, caused by hypotension;
• fatigue.

Frequent (< 1 из 10 человек):

• slow heartbeat;
• balance problems;
• cold extremities;
• heartbeat;
• headache;
• stool disorders;
• abdominal pain;
• shortness of breath during physical activity.

Less frequent (< 1 из 100 человек):

• temporary worsening of symptoms of heart failure;
• fluid retention (swelling);
• chest pain;
• tingling;
• muscle cramps;
• vomiting (nausea);
• weight gain;
• decrease in concentration;
• sleep disorders (insomnia);
• drowsiness;
• nightmares;
• dyspnea;
• skin rash;
• increased sweating.

Rare (< 1 человека из 1000):

• worsening diabetes;
• nervousness;
• anxiety;
• ophthalmic problems;
• impotence;
• Peyronie's disease;
• irregular heartbeat;
• heart failure;
• dry mouth;
• nasal discharge;
• hair loss;
• changes in liver test results.

very rare (< 1 из 10 000 человек):

• changes in the number of blood cells;
• memory disorder;
• confusion;
• hallucinations;
• mood swings;
• tinnitus;
• hearing disorders;
• taste changes;
• hepatitis;
• photosensitivity;
• exacerbation of psoriasis;
• muscle weakness;
• joint pain;
• tissue necrosis in patients with severe circulatory disorders.

Contraindications for use

Do not take Egiloc if:

• allergy to metoprolol, other β-blockers, any other drug ingredients;
• cardiac conduction disorder (atrial or ventricular block II or III degree), heart rhythm problems (sick sinus syndrome);
• untreated heart failure, therapy aimed at increasing heart rate, shock due to heart failure;
• severe circulatory problems (severe peripheral circulatory disorders);
• low heart rate (less than 50/minute);
• hypotension;
• metabolic acidosis;
• severe asthma, COPD;
• untreated pheochromocytoma;
• heart failure with blood pressure below 100 mm Hg. Art.

Replacement of Egilok is necessary when taking the following medicines:

• monoamine oxidase inhibitors (for depression);
• Verapamil and Ditylazam (for hypertension);
• antiarrhythmic drugs (Dispopyramide).

Drug analogues

In some cases (for example, due to intolerance to the components), it is recommended to use substitutes for Egilok tablets; what they are used for, dosage and special instructions indicated in the instructions, which must be read before starting treatment.

The analogues of the drug include the following drugs:

• Betaloc ZOK - contains a similar active ingredient;
• , - active substance bisoprolol;
• Nebilet - the active ingredient is nebivolol.

Egilok VS Concor

Which medicine to choose - Egilok or Concor? What's better? Both drugs are prescribed for hypertension and heart rhythm disturbances. But they have different active ingredients.

There is also a difference in price. The cost of Concor is almost twice as high as the price of Egilok.

A number of contraindications have both means, which requires careful study of the instructions.