Erespal causes drowsiness. What kind of cough does erespal help with? Cheap analogues of "Erespal"

Many people are interested in the question of what cough Erespal helps with. Application medicine in case of severe coughing attacks, it helps restore breathing and alleviate the patient’s condition. The medication has several release forms: they are different for adults and children. The manufacturing company (Les Laboratoires Servier) is located in France.

Erespal is an effective bronchodilator, the use of which for medicinal purposes should be carried out according to the instructions. The presence of contraindications prescribed in the annotation makes it impossible to use the drug. Prices may vary depending on the location of sale.

Composition and release form

Concentration active substance- fenspiride hydrochloride - may vary depending on the release form. The drug is marketed in tablet and syrup form. Cough tablets are round, milky, biconvex, coated with an enteric film. They contain 80 mg of the active ingredient and a number of additional substances:

• microcellulose;
• polyvinylpyrrolidone;
• anhydrous silicon (dioxide);
• magnesium salt of stearic acid.

Children's medicine is a slightly caramelized (consistency) suspension of brownish-yellow color. The concentration of the main component in Erespal syrup does not exceed 2 mg per 1 ml of product. Auxiliary components provided by the manufacturer:

• purified water;
• glycerol;
• flavoring;
• sucrose (sweetener);
• licorice root (extract);
• vanilla infusion.

Anti-inflammatory cough syrup is sold in dark glass bottles, hermetically sealed with an aluminum stopper (150 ml). Pills - in blisters of 10-30 pcs. All forms of release are sold in cardboard boxes, inside of which there is an annotation.

Action of Erespal for cough

Erespal, like most cough medicines, has anti-inflammatory, mucolytic, antimicrobial and antispasmodic properties. When the active substance enters the body, it quickly reaches the site of inflammation and reduces the productivity of cytokines and free radicals involved in the inflammatory process.

Syrup and tablets help with chronic cough(for smokers). With regular use, the severity of inflammation decreases and swelling subsides. Thanks to its antihistamine properties, the medication eliminates discomfort in the throat (stingling, burning, pain). A decrease in muscle tone ensures expansion of the lumen of the bronchopulmonary tract.

Indications for use

Main indications for use: relief of severity clinical syndrome. In addition to coughing, the medication helps get rid of a number of pathologies.

What cough should I take Erespal for?

Before answering the question for which cough Erespal can be taken, it is necessary to determine the type of clinical syndrome. There are several main types of cough: dry cough and wet cough, accompanied by sputum production. The drug can be used in both cases. With a dry cough, Erespal eliminates irritation, with a wet cough, it thins the mucus in the bronchi.

Erespal for dry cough

Erespal for dry cough helps reduce attacks of unproductive cough. The medication gradually transforms a dry cough into a wet one. Another function of the medicine for barking cough in children and adults is protective. It protects the mucous membrane from ruptures and damage. Baby syrup from a dry cough, dilates the bronchi, eliminates bronchospasms, soreness and a feeling of dryness in the throat.

Erespal for wet cough

Erespal with a wet cough eliminates swelling of the bronchi and stops the spread of the inflammatory process to healthy areas of the respiratory system. The smooth muscles relax - against the background of this, the patient experiences shortness of breath and painful phenomena that accompany coughing attacks. Long-term use of the drug for wet cough helps prevent relapse.

What does Erespal treat besides cough?

Main indications for use: diseases internal organs breathing. The instructions for use describe the following pathologies:

• inflammation of the larynx;
• nasopharyngitis;
• inflammation of the bronchi;
• tracheobronchitis;
• pneumonia (pneumonia);
• bronchial type asthma;
• respiratory manifestations of whooping cough, ARVI, measles rubella (sore throat, coughing, hoarseness);
• diseases of infectious etiology.

The medicine for children is taken when diagnosing the following diseases:

• rhinitis (acute);
• pharyngitis;
• laryngitis;
• laryngotracheitis;
• tracheitis.

The medication is approved for use for sinusitis and otitis of various etiologies.

Contraindications and side effects

The drug has contraindications, which depend on the form of release. Restrictions for taking the tablet form:

• hypersensitivity;
• individual intolerance to individual components of the drug;
• diabetes;
• children's age (up to 18 years).

For the medicine:

• age restrictions (up to 2 years);
• disturbances in digestion processes (enzyme deficiency).

Any ailments accompanying the use of medication are classified as side effects. They occur against the background of an incorrectly selected dosage regimen. Most often, side effects are observed from the internal organs and the central nervous system.

From the digestive organs, ailments are expressed in the form pain in the area of ​​epigastrium, stool disorders (diarrhea) and vomiting. From the outside of cardio-vascular system There is a rapid heartbeat and surges in blood pressure.

Dizziness, headaches and sleep disturbances are attributed to side effects from the nervous system. Most often, children experience all kinds of allergic reactions in the form of facial flushing, erythema, and urticaria. Skin itching and burning sensation are the most common manifestations of allergies. With prolonged use of the syruped form, the child quickly gets tired.

Instructions for use Erespal

Before using the medicine, you must carefully study the instructions for use of Erespal, included inside the box. The medicine is prescribed by the doctor based on the results of tests previously taken by the patient. The course of application and dosage regimen is determined individually depending on the age of the patient.

For adults

The daily dosage of the drug for adult patients should not exceed 240 mg, which is equivalent to 3 tablets. The drug must be taken at the same time, 15 minutes after eating. The tablets are drunk whole, without breaking or chewing. You can take the medicine only with boiled water - carbonated drinks, energy drinks, tea and coffee cannot be used for these purposes. The period of application is no more than 10 days.

For children

The therapeutic norm of the mixture for children is determined based on the body weight and age of the child. For convenience, the medicine is poured into a bottle (for children under 3–4 years old). Before opening, it is recommended to shake the bottle vigorously for 20–30 seconds - this will dissolve the sediment.

It is recommended to give 4 mg/1 kg to children under 4 years of age - if the baby weighs less than 10 kg, then he should be given 1 teaspoon of syrup once before or during meals. If the child's weight exceeds 10 kg, he is given 1 tbsp. l. emulsions once. Adolescent children (12 years and older) are given 2 tbsp once. l. You can take no more than 5–6 tablespoons of the product per day. The course of admission is 7–10 days.

Pregnant

The use of Erespal for medicinal purposes during pregnancy is possible for health reasons in the absence of a threat to the health of the mother and fetus. The appointment is carried out under the supervision of a specialist. The recommended dosage regimen is to take half doses (no more than 120 mg/day). The course of treatment must be reduced by 2 times. If any organ problems occur digestive tract and nervous system, the use of the medication must be stopped immediately.

Interaction with other drugs

A bronchodilator is often combined with antiviral, immunomodulatory, and mucolytic agents. With the simultaneous use of Erespal and antihistamines the sedative effect of the bronchodilator may be enhanced.

Experts recommend taking vitamins simultaneously with the medication. Against the background of infectious diseases, the body’s defense reactions decrease, so treatment with an anti-inflammatory drug is accompanied by the intake of vitamin-mineral complexes (Supradin Kids, Kaltsinova, Pikovit).

How much does syrup and tablets cost?

The medicine is in the middle price category; prices for the medicine and tablets vary depending on the region and place of sale. The cost of the tablet form is from 300 rubles, the price of syrup is from 230 rubles. Both dosage forms can be ordered on the manufacturer's official website - in this case the price will be higher than in pharmacies. Shipping costs will be included.

Analogs

Erespal syrup and tablets have several structural analogues that have therapeutic properties similar to the original. Analogues of the drug for adults:

1. . Syrup plant origin contains extracts of thyme, primrose and grindelia. Auxiliary components - sugar syrup, sodium benzoate. Used for attacks of wet and dry cough. The cost of the drug is 320 rubles.
2. Ascoril. The drug is sold in the form of syrup and tablets. It contains several active ingredients (menthol, guaifenesin, salbutamol sulfate, bromhexine hydrochloride). The medicine is used for medicinal purposes for dry nonproductive cough. Cost - from 380 rubles.

The closest analogue of children's medicine is Lazolvan syrup. The active ingredient is ambroxol. The mucolytic has a pleasant fruity aroma and taste; it can be used for bronchitis, pharyngitis, tracheitis and laryngitis in children.

When asked by patients which is better - Erespal or Askoril (, Lazolvan, etc.), there is no clear answer. Drugs act differently on the body due to its individual characteristics.

Erespal is a bronchodilator and anti-inflammatory drug intended for the treatment of inflammatory diseases upper and lower respiratory tract, accompanied by severe inflammation, swelling and bronchospasm. It contains the active substance - fenspiride hydrochloride, which belongs to pharmacological group- H1-antihistamines and is therefore an anti-inflammatory agent, with an antihistamine, myotropic antispasmodic and antiexudative mechanism of action and has a bronchodilator effect. Therefore, this drug is one of the drugs included in regimens for the complex treatment of bronchial asthma.

Phakmacodynamics of Erespal

The mechanism of action of erespal is its pronounced anti-inflammatory, anti-edematous and antispasmodic effect on the mucous membrane of the upper and lower respiratory tract, as well as its anticonstrictor effect on the bronchial tree. Its action is based on active blockade of H1-histamine receptors, inhibition of arachidonic acid metabolism and blockade of alpha-adrenergic receptors. The effect of fenspiride on arachidonic acid metabolism occurs indirectly through calcium metabolism, which is a regulator of the activity of phospholipase A, which promotes the formation of arachidonic acid. Thus, it antagonizes the mediators of allergy and inflammation - histamine, serotonin and bradykinin, reduces the production of leukotrienes and prostaglandins, which are also stimulated by histamine, and reduces the secretion of bronchial glands and has a chemotactic effect. When used in high doses fenspiride significantly inhibits the production of inflammatory agents in the mucous membranes: free radicals, cytokines, tumor necrosis factor alpha and arachidonic acid metabolites. Some of these inflammatory factors have a bronchoconstrictor effect, so a decrease in their production causes an antiasthmatic and bronchodilator effect. In this regard, the activity and release of a number of factors that contribute to the development of inflammation, hypersecretion of inflammatory agents and bronchial obstruction decreases. It also has a paperrine-like myotropic antispasmodic effect.

Fenspiride in its mechanism of action differs from all anti-inflammatory drugs (non-steroidal and steroidal anti-inflammatory drugs), since it has an original effect on the inflammatory process and affects all inflammatory mediators.

Pharmacokinetics of Erespal

Erespal has good absorption from gastrointestinal tract. Its maximum concentration in the blood plasma after taking the syrup is achieved after 2.3 hours, and when taken in tablet form - after 6 hours, on average from 0.5 to 8 hours and depends on the absorption capacity of the intestine. Erespal is excreted from the body 90% by the kidneys, and 10% through the intestines. The half-life of the drug from the body is 12 hours.

Instructions for use of Erespal

Due to its high efficiency, excellent anti-inflammatory and bronchodilator effects, this drug is used for most diseases of the upper and lower respiratory tract as an anti-inflammatory, bronchodilator, anti-edematous, antispasmodic agent.

Indications:

1. Acute nasopharyngitis, acute laryngitis, acute laryngotracheitis;
2. Acute nasotracheobronchitis, acute bronchitis, acute obstructive bronchitis;
3. Acute otitis media, acute sinusitis of various etiologies;
4. Bronchospastic syndrome in acute respiratory infections, acute respiratory viral infections;
5. Bronchial asthma;
6. Measles, whooping cough (to eliminate respiratory disorders and bronchospasm);
7. Infectious diseases of the respiratory tract, complicated by spastic cough syndrome and bronchial obstruction;
8. Chronic nasopharyngitis, chronic laryngitis and chronic laryngotracheitis;
9. Chronic bronchitis (against the background of respiratory failure or its absence);
10. Chronic otitis media, chronic sinusitis

Instructions for using erespal

This drug has two forms of release: in the form of syrup and tablets and is produced by Servier Laboratories in France.

The syrup is available in 150 ml dark plastic bottles containing 2 mg of the active substance fenspiride per 1 ml of syrup.

The tablet form of erespal consists of tablets of 15 pieces in a blister, coated film-coated and containing 80 mg of fenspiride.

The syrup is an orange transparent liquid, taken orally before meals, it is advisable to shake it before use.

The dose for adults and adolescents is: three to six tablespoons per day, which is 45-90 ml. One tablespoon of syrup contains 30 mg of fenspiride.

For adults, Erespal tablets are prescribed 1 tablet (80 mg) two to three times a day.

For children under fourteen years of age, erespal is prescribed only in the form of syrup.

For body weight up to ten kilograms - 10-20 ml per day, from two to four teaspoons daily, the drug can be added to a bottle of baby food;

from two to sixteen years, with a weight of more than ten kilograms, the recommended dose is 2-4 tablespoons of syrup, which corresponds to 30-60 ml daily.

Contraindications

Contraindications for use are individual hypersensitivity to active substance medicinal product - fenspiride hydrochloride or another component included in the medicinal product (most often sunset yellow CFC dye or propylarbenam).

Taking the tablet form of the drug is also contraindicated for children under 14 years of age.

Special instructions and interactions with other drugs

This drug should be taken with caution in patients with fructose intolerance, with glucose-galactose maladsorption, in patients suffering from diabetes mellitus and with isomaltose deficiency (due to the presence of sucrose in the composition of the drug).

It is not recommended to take the drug together with acetylsalicylic acid and other non-steroidal anti-inflammatory drugs due to the possibility of developing allergic reactions, including bronchospasm.

It is also not recommended to prescribe erespal together with a sedative group of drugs, since their interaction can lead to potentiation of the sedative effect and cause severe weakness and drowsiness (histamine H1 receptor blockers have their own sedative effect).

For the same reason, it is not advisable to combine the use of erespal and alcohol.

For inflammatory diseases of infectious origin, complicated bacterial infection, erespal is prescribed in combination with antibacterial drugs.

Side effects of Erespal

Side effects of erespal include changes in the central nervous system in the form of drowsiness and dizziness;

from the cardiovascular system - palpitations and moderate tachycardia, which decreases with decreasing dose of the drug;

from the outside digestive system – gastrointestinal disorders, nausea, epigastric pain, sometimes vomiting and diarrhea;

Allergic reactions may also occur in case of individual sensitivity to the drug in the form of erythema, urticaria, angioedema, as well as asthenia, fatigue, and fixed erythema pigmentosa.

If any of these symptoms occur, you should immediately stop using Erespal and consult your doctor.

Overdose

An overdose of a drug occurs when the drug is taken in dosages exceeding the average daily allowable dose, when the drug accumulates in the body, which occurs when it is taken for a long time or when excretion is impaired.

Symptoms of an overdose of erespal are agitation or drowsiness, nausea, vomiting, and sinus tachycardia.

Sometimes situations arise when Small child drinks a large amount of medicine. In the case of erespal, this can be extremely dangerous due to its adrenergic blocking and histamine blocking effects, which can provoke an attack of sinus tachycardia, accompanied by severe weakness, drowsiness or overexcitation.

All organs and systems of the child’s body are characterized by ongoing differentiation, and therefore insufficient stability and a paradoxical reaction to a large simultaneous administration of the drug, and the delicate gastric mucosa contributes to faster absorption of the drug into the bloodstream. Therefore, if a situation arises where a child, out of ignorance or out of curiosity, takes a large dose of erespal, it is necessary to immediately contact medical institution behind medical care for gastric lavage and, if necessary, symptomatic drug therapy, detoxification measures and ECG monitoring.

Also no less dangerous when taken large quantity drug, both in children and adults, especially in old age - the occurrence of allergic reactions in the form of angioedema or Quincke's edema, which are immediate-type allergic reactions and are characterized by a rapid course. Therefore, if they occur, you must immediately contact a medical facility.

Instructions for using erespal during lactation and pregnancy

Taking this drug during pregnancy is not recommended, as there is always a risk of adverse effects of the drug on the embryo (when used in early stages) or on the developing fetus (for more late stages pregnancy). Some sources contain data on the teratogenic effect of fenspiride hydrochloride with the development of an anomaly of the upper palate in the form of a “cleft palate”. But therapy with erespal is not a basis for termination of pregnancy, since in general there is no clinical data on its teratogenic effect, and in this case the protective properties of the fetoplacental barrier and the individual characteristics of the course of pregnancy and the activity of the mother’s excretory systems should not be excluded.

Also, when breastfeeding a child, taking Erespal is not recommended, since the active components of the drug that enter breast milk can enter the child’s body and adversely affect its organs and systems, in particular causing increased drowsiness or overexcitation, as well as sinus tachycardia. Reception this drug is possible only if you temporarily refuse breastfeeding, due to the fact that studies on the concentration of the active substance in breast milk have not been conducted for a child, especially a newborn, they may exceed the maximum permissible dose of the drug for his weight.

Practice of using erespal and reviews

Erespal is an excellent development of the pharmacological company Servier Laboratories, introduced in Russia back in 1998 and today is a very effective and popular drug that is widely used in medical practice - therapy, otolaryngology and pediatrics, as an anti-inflammatory and bronchodilator drug. It is prescribed for inflammatory diseases of the upper and lower respiratory tract of infectious and allergic origin, which are accompanied by spasm and severe cough - acute and chronic laryngitis, pharyngitis, laryngotracheitis, acute, chronic and obstructive bronchitis. It is also effective as a symptomatic remedy used in complex therapy with severe cough and spasm of the larynx and bronchi with whooping cough and parawhooping cough, spasmodic cough with measles and parainfluenza infection. Erespal has a potentiating anti-inflammatory effect when used together with antibacterial drugs for infectious and colds of the upper and lower respiratory tract, complicated by bacterial infection.

This drug is very effective in complex and maintenance therapy regimens for bronchial asthma, which is due to its dual mechanism of action at all stages of development pathological process with this disease - bronchodilation, inhibition of mucus production, anti-edematous and anti-inflammatory effect, as well as inhibition of the production of histamine and serotonin, which potentiates its antiallergic effect.

Erespal is used in otolaryngology for the treatment of acute and chronic inflammatory processes of the paranasal sinuses and nasal cavity - sinusitis and rhinitis. It is used in combination with other drugs: antibacterial, desensitizing and local anti-inflammatory drugs. In this case, erespal, which has an anti-inflammatory effect on the mucous membrane paranasal sinuses nose and stimulating effect on mucociliary transport, has proven itself in the treatment of purulent and pollipous sinusitis and rhinosinusitis.

Its effective practical use in combination with desensitizing drugs, allows us to recommend erespal for the treatment of patients with combined chronic inflammatory process in the upper and lower respiratory tract, including bronchial asthma, subacute laryngotracheitis and exacerbations of chronic laryngitis.

At clinical application the drug has excellent tolerability, even with long-term use.

Erespal storage conditions

Like all medications erespal should be used only before its expiration date. It can be stored for no more than three years in a sealed form.

Related materials:

Runny nose during pregnancy

Erespal is a bronchodilator and anti-inflammatory drug intended for the treatment of inflammatory diseases of the upper and lower respiratory tract, accompanied by severe inflammation, edema and bronchospasm.

The drug is one of the drugs included in the regimens for complex treatment bronchial asthma.

Erespal instructions for use

Composition and release form

Erespal tablets

Film-coated tablet.

1 tablet contains:

Active substance: fenspiride hydrochloride 80 mg.

Excipients: calcium hydrogen phosphate; hypromellose; povidone; anhydrous colloidal silicon dioxide; magnesium stearate; titanium dioxide; glycerol; macrogol 6000.

Erespal syrup

Plastic bottles (2 mg/ml) - 150 ml.

Indications for use

Diseases of the upper and lower respiratory tract:

• rhinopharyngitis and laryngitis;
• otitis and sinusitis of various etiologies, including allergic (both seasonal and permanent);
• rhinotracheobronchitis;
• bronchitis (with or without chronic respiratory failure);
• complicated or isolated bronchial asthma (maintenance therapy);
• respiratory phenomena with measles, whooping cough, influenza (Erespal syrup).

Pharmacokinetics

Erespal is absorbed from the gastrointestinal tract relatively slowly. After oral administration of Erespal tablets, Cmax is achieved after 6 hours, after taking Erespal syrup - after 2.3±2.5 hours (from 0.5 to 8 hours). Elimination T1/2 is 12 hours. Erespal is excreted mainly in the urine.

Directions for use and doses

Pills

Erespal should be taken before meals.

• For adults: Prescribe 2-3 tablets (80 mg) per day.
• Children under 14 years old It is not tablets that are recommended, but syrup.

The syrup should be shaken before use. For children and adolescents under 14 years of age, Erespal is prescribed at a dose of 4 mg/kg body weight.

• For adults: 3-6 tablespoons (45-90 ml) of syrup per day. 1 tablespoon of Erespal contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.
• Children from 0 to 2 years (body weight up to 10 kg): 2-4 teaspoons of Erespal syrup (10-20 ml), can be added to a bottle with food. 1 teaspoon of Erespal contains 10 mg. fenspiride hydrochloride and 3 g of sucrose.
• Children aged 2 to 16 years (body weight more than 10 kg): 2-4 tablespoons of Erespal syrup (30-60 ml).

A course of treatment

20-30 days. A repeated course is possible after consultation with a doctor.

Contraindications for use

Childhood up to 14 years (for Erespal tablets) - hypersensitivity to the active substance and/or any of the components of Erespal, especially to Sunset yellow CFC dye, methyl and propylparabens (for syrup).

Pregnancy and lactation

While taking Erespal during lactation, you should stop breastfeeding, because There is no data on the excretion of fenspiride in breast milk.

Side effects

From the digestive system: nausea, stomach pain, vomiting. Allergic reactions: very rarely - erythema, Quincke's edema, fixed erythema pigmentosa, rash; Due to the presence of para-hydroxybenzoate in Erespal syrup, urticaria may develop.

Others: drowsiness; rarely - moderate tachycardia, disappearing after discontinuation of Erespal.

Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

special instructions

If the disease is infectious, treatment with Erespal is carried out in combination with standard antibiotic therapy. Erespal in syrup form should be prescribed with caution to patients with hypersensitivity to acetylsalicylic acid and other NSAIDs due to the risk of allergic reactions, including asthmatic attacks (including bronchospasm) in this category of patients due to the fact that Erespal syrup contains sunset yellow CFC dye.

Since Erespal syrup contains sucrose, it should be prescribed to patients with diabetes mellitus with caution, because Dosage adjustment of hypoglycemic drugs may be required.

Due to the presence of sucrose, Erespal in syrup form should not be administered to patients with fructose intolerance, glucose-galactose malabsorption syndrome or sucrazoisomaltase deficiency (a rare metabolic disorder when using Erespal).

Erespal reviews

The drug is “rubbish”, after taking one pill my blood pressure jumped, my heart rate increased, and all the signs described above, I threw it to hell in the trash! On Monday I’ll go to the therapist and ask why the hell she prescribed this crap for me, knowing that I have a problem with blood pressure?! Be careful, take care of yourself!

The drug is good. The only negative is that I get itching from this drug, apparently a reaction to some components. But between the cough and the itching, I chose the itching. In general, you can use it - but wisely. It is imperative to read the instructions, all the contraindications are listed there, and who is generally undesirable to drink it, and what side effects there are. Better yet, consult a doctor.

I was prescribed for the treatment of bilateral purulent sinusitis, the first day there was a slight palpitation, on the second I drank in the morning and at lunch, I could no longer get out of bed, my heart was jumping out of my chest so that I could not walk or lie down, I did not drink in the evening. In the morning I went to the doctor, changed the drug and immediately felt better.

We took it for the flu, the syrup is not for the faint of heart, let me tell you. It’s a serious thing, of course - it relieves a wet cough perfectly, it removes inflammatory processes well, but the instructions with contraindications are downright scary to read. While we were drinking with the child, we were always afraid that one of the symptoms would appear. But I was lucky, everything went well. In general, all medications have certain contraindications, the main thing is not to overdo it with the dosage and carefully monitor the condition during the intake process.

Yesterday I took only 3 tablets according to the doctor's prescription. After lunch, my muscles began to ache terribly. At night I rubbed it with a rub. By morning the pain had not gone away. I had tachycardia, but my heartbeat didn’t bother me. And at 3 am the stomach upset began. Today I will ask the doctor for a replacement. It’s a pity that I didn’t read the reviews. Organisms are different, the reactions are also different. Be careful and healthy.

The contraindications there, of course, are not too bad - on the other hand, you can drink syrup from almost zero age. The kind of drugs that could be prescribed to very little ones, once or twice, is too numerous. So here - depending on your luck. I think the main thing is not to give such drugs to a child if he has at least a hint of contraindications (diabetes, or sensitivity to fructose). One tablet is quite enough, especially since the minimum dose in the instructions is always somewhat too high. Divide the tablet in half and drink the drug twice a day. What makes Erespal especially good is that it is a real salvation for dry coughs that turn into bronchospasm. If you are afraid, start taking half a tablet a day; if there are no side effects, you can gradually increase the dose.

I read the reviews in shock what happened to you, the doctor prescribed Erespal, I wasn’t even treated for the entire course - I was cured, everything is fine, I don’t complain about anything, no pressure or shaking - maybe you took it with what other medicine? Regular paracetamol-based tablets are not able to cure all colds, which is why antibiotics are more effective, but should be taken naturally if prescribed by a doctor.

Compound:

Description
Clear liquid orange color, the formation of a sediment is possible, which disappears when shaking.

Pharmacotherapeutic group
Anti-inflammatory, antibronchoconstrictor agent.

ATX code: R03DX03

PHARMACOLOGICAL PROPERTIES
Pharmacodynamics
An anti-inflammatory agent, has an antiexudative effect, prevents the development of bronchospasm. Shows antagonism with mediators of inflammation and allergy: serotonin, histamine (blockade of H1-histamine receptors), bradykinin. Has a myotropic antispasmodic effect.
When administered in large doses, it reduces the production of various inflammatory factors (cytokines, arachidonic acid derivatives, free radicals).

Pharmacokinetics
Well absorbed from the gastrointestinal tract.
The maximum concentration in blood plasma after oral administration is achieved after 2.3 ± 2.5 hours (from 0.5 to 8 hours). The half-life is 12 hours.
It is excreted mainly by the kidneys (90%), 10% through the intestines.

INDICATIONS
Diseases of the upper and lower respiratory tract:

• Rhinopharyngitis and laryngitis;
• Tracheobronchitis;
• Bronchitis (with or without chronic respiratory failure);
• Bronchial asthma (as part of complex therapy);
• Respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough and influenza;
• At infectious diseases respiratory tract, accompanied by cough, when standard antibiotic therapy is indicated.

CONTRAINDICATIONS
Hypersensitivity to the active substance and/or any of the components of the drug.
Children under 2 years of age.

WITH CAUTION:
Patients with fructose intolerance, glucose-galactose malabsorption, sucrase/isomaltase deficiency (due to the presence of sucrose in Erespal ® syrup), patients with diabetes mellitus (due to the presence of sucrose in Erespal ® syrup).

PREGNANCY AND BREASTFEEDING
Taking the drug during pregnancy is not recommended.
Fenspiride therapy is not a reason to terminate an ongoing pregnancy.
There are no clinical data on the fetotoxic effect of fenspiride or its ability to cause malformations when taken during pregnancy.
Erespal ® should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

METHOD OF APPLICATION AND DOSES
STRICTLY FOLLOW YOUR DOCTOR'S RECOMMENDATIONS.
Inside.
Shake before use.
Adults and teenagers:
From 3 to 6 tablespoons of syrup (45 - 90 ml) per day, take before meals.
Children from 2 years old:
Recommended dose 4 mg/kg/day.
- body weight up to 10 kg: from 2 to 4 teaspoons of syrup per day (or 10 – 20 ml), can be added to a bottle with food
- body weight more than 10 kg: from 2 to 4 tablespoons of syrup per day (or 30 – 60 ml), take before meals

1 tablespoon (15 ml of syrup) contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.
1 teaspoon (5 ml of syrup) contains 10 mg of fenspiride hydrochloride and 3 g of sucrose.

The duration of treatment is determined by the doctor.

SIDE EFFECT
INFORM YOUR DOCTOR ABOUT ANY ADVERSE REACTIONS AND SENSATIONS YOU EXPERIENCE, INCLUDING THOSE NOT MENTIONED IN THIS INSTRUCTION, AS WELL AS CHANGES IN LABORATORY VALUES DURING THE THERAPY.
Frequency adverse reactions that may occur during therapy are given in the following gradation: very often (>1/10); often (>1/100, 1/1000, 1/10000, From the cardiovascular system
Rarely: moderate tachycardia, the severity of which decreases with decreasing dose of the drug.
From the digestive system
Often: gastrointestinal disorders, nausea, epigastric pain.
Unspecified frequency: diarrhea, vomiting.
From the central nervous system
Rarely: drowsiness.
Unspecified frequency: dizziness.
Common disorders and symptoms
Unspecified frequency: asthenia, increased fatigue.
From the skin and subcutaneous fat
Rarely: erythema, rash, urticaria, angioedema, fixed erythema pigmentosa.
Unspecified frequency: itchy skin.
Risk of reactions hypersensitivity for Sunset Yellow S dye, which is part of the drug.

OVERDOSE
In case of an overdose of the drug (cases of overdose have been reported when taking the drug at a dose of more than 2320 mg), you should immediately seek medical help.
Symptoms: drowsiness or agitation, nausea, vomiting, sinus tachycardia.
Treatment: gastric lavage, electrocardiogram (ECG) monitoring.
Keeping Vital important functions body.

INTERACTION WITH OTHER MEDICINES
No special studies have been conducted on the interaction of fenspiride with other drugs.
Due to the possible increase in sedative effect when taking histamine H1 receptor blockers, it is not recommended to use Erespal ® syrup in combination with drugs that have a sedative effect, or in combination with alcohol.

SPECIAL INSTRUCTIONS
The drug contains parabens (parahydroxybenzoates), as a result of which taking this drug can provoke the development of allergic reactions, including delayed ones.
When prescribing the drug to patients with diabetes, it is necessary to take into account that Erespal ® syrup contains sucrose (1 teaspoon – 3 g of sucrose = 0.3 XE; 1 tbsp. spoon – 9 g of sucrose = 0.9 XE).
Studies examining the effect of the drug Erespal ® on the ability to drive vehicles and no work was carried out with the mechanisms. Patients should be aware of the possible development of drowsiness when taking the drug Erespal ®, especially at the beginning of therapy or when combined with alcohol intake, and should be careful when driving vehicles and when performing work that requires high speed psychomotor reactions.

RELEASE FORM
Syrup 2 mg/ml. 150 ml of syrup in a brown plastic bottle (PVC) with a plastic cap with tamper evident. One bottle with instructions medical use placed in a cardboard box.

STORAGE CONDITIONS
Special conditions no storage required.
Keep out of the reach of children.

BEST BEFORE DATE
3 years.
DO NOT USE AFTER THE EXPIRATION DATE STATED ON THE PACKAGING.

VACATION CONDITIONS
On prescription.

Registration certificate issued to Servier Laboratories,
France, produced by Servier Industry Laboratories, France

"Servier Industry Laboratories":
905, highway Saran, 45520 Gidie, France
905, route de Saran, 45520 Gidy, France

For any questions, please contact the representative office of Servier Laboratories JSC. Representative office of JSC Servier Laboratories:
115054, Moscow, Paveletskaya sq. d.2, p.3

The instructions included in the package additionally indicate the Servier Laboratories logo.

Registration Manager: Irina Kolotushkina

Erespal is a modern drug used to treat coughs that occur with various inflammatory processes and infections in the respiratory tract. Cough is one of the most unpleasant consequences of the flu. And although by its nature this is one of the protective mechanisms that helps the body fight infection, it does not make it any easier. Often a cough is accompanied by spasm of the bronchi and obstruction of their patency (bronchoconstriction). Cough is especially dangerous for young children, for whom it causes great suffering.

Description

The main component of the drug is fenspiride hydrochloride. This substance has a triple effect on the body. First, it reduces inflammation. Secondly, it acts on histamine receptors and thereby blocks the production of mucus in the bronchi. Thirdly, it has an antispasmodic effect. Therefore, the use of Erespal contributes to the expansion of the bronchi.

The principle of action of the drug is fundamentally different from the principle of action of other antitussive drugs. They are divided into two large groups. Some of them affect the so-called dry cough, that is, a cough without the formation of sputum. Others help to liquefy this phlegm and remove it from the body.
Erespal does not belong to any of these groups. But this does not prevent him from being highly effective. The reason is that the drug fights not so much the consequences of inflammation as it suppresses the mechanism of its occurrence. In addition, fenspiride suppresses the cough reflex without affecting the corresponding center of the brain.

One of the advantages of the drug is that it can also be useful for viral infections. respiratory infections(ARVI), for which antibiotics do not work. This is achieved due to the fact that it has a strong anti-inflammatory effect.

Most of the drug is excreted through the kidneys, and about one tenth through the intestines.

Indications for use:

• laryngitis
• pharyngitis
• bronchial asthma
• flu
• sinusitis

A natural question arises: can Erespal serve as a substitute for treating the body with antibiotics? Of course no. Erespal is primarily an antitussive drug and cannot be the only method of treating infectious diseases.

Release forms and composition

The drug is available in two dosage forms: in tablets with a dosage of 80 mg and Erespal for children in the form of syrup in 150 ml bottles. Each box of the drug contains detailed instructions, which should be read carefully.

Compound

Fenspiride hydrochloride is a rather bitter substance. Therefore, the syrup contains many sweeteners and flavorings so that children take the medicine with pleasure.

Composition of the tablet:

• fenspiride
• calcium phosphate disubstituted
• hypromellose
• povidone
• colloidal anhydrous silicon
• Magnesium stearate
• titanium dioxide
• glycerol
• macrogol 6000

The syrup is sold in 150 ml bottles. 1 ml of syrup contains 2 mg of fenspiride.

Other substances included in the syrup:

• honey flavor
• licorice root extract
• glucose
• anise oil
• vanillin extract
• glycerol
• Sunset Yellow S dye
• methyl parahydroxybenzoate
• propyl parahydroxybenzoate
• saccharin
• sucrose
• potassium sorbate
• distilled water

Erespal is produced by the French pharmaceutical company"Servier Laboratory". This is a proven and reliable supplier. However, as with many other imported medicines, the price of the drug may seem too high. In this case, you can look for analogues of the drug containing fenspiride. Such drugs include the drugs Fenspiride, Erispirus, Codestim, Fosidal and some others. However, when selecting an effective drug, you should focus not only on prices, since drugs of lower cost may be inferior in quality. Other antitussive drugs can hardly replace Erespal, since they do not have an antihistamine and antispasmodic effect.

The drug is sold in pharmacies with a prescription. Erespal is stored at room temperature. The shelf life of tablets is 3 years, syrup - 2 years.

Erespal, instructions for use

Before taking Erespal, you should read the instructions for use that come with the drug. The drug is very well absorbed by the body when taken orally and begins to act after just a few hours. For tablets, the therapeutic effect begins to appear after 2-3 hours, for syrup – after an hour. The maximum effect of the medicine reaches after 6 hours. In case of overdose, consult a doctor.

Instructions for use of tablets for adults

According to the instructions, you need to take two 80 mg tablets per day. In severe cases of the disease, the doctor may increase the frequency of administration to 3 times a day. The duration of treatment is also determined by the doctor. In most cases, improvement occurs within 2-3 days. According to Erespal's instructions, the drug is usually taken before meals.

Erespal tablets are intended for adults only. Children under 14 years of age are prohibited from taking them. To treat children, it is better to use Erespal in syrup form, while following the instructions.

Instructions for use of syrup for children

The dosage of syrup for children depends on the child’s body weight. It must be selected so that daily dose would not exceed 4 mg/kg body weight. Typically, for children weighing less than 10 kg, syrup is prescribed at 2-4 teaspoons per day, and for children heavier than 10 kg - 2-4 tablespoons. Erespal syrup can be taken by children from 2 years of age. A child under 2 years of age should not be given the drug in any form. Adults should take Erespal syrup 2-3 tablespoons (45-90 ml) per day.

Contraindications

The drug has very few contraindications. First of all, it is not recommended to give the drug to children under 2 years of age. Secondly, this is individual intolerance to the active substance and auxiliary components included in the drug. Since the syrup contains sucrose, it is contraindicated for patients with diabetes. Such patients should take tablets.

Interaction with other drugs

If you are taking other cough suppressants at the same time, you should consult your doctor. It is not recommended to take Erespal with sedatives and alcohol, since the drug, as an antihistamine, has its own sedative effect, which will enhance the sedative effect of other drugs.

Also, in the case of simultaneous use of Erespal, alcohol and other sedatives, one should be wary of a deterioration in the reaction rate. This should be taken into account by those who drive vehicles.

Side effects

Rarely may be observed:

• allergic reactions, nausea, drowsiness and lethargy
• moderate tachycardia
• gastrointestinal disorders
• epigastric pain
• drowsiness
• erythema
• hives
• angioedema