Flucinar ointment purpose. Flucinar ointment: what helps and method of application. Instructions - correct use of Flucinar

Many who have encountered this problem are probably familiar with flucinar ointment. skin rashes of various nature. Psoriasis, eczema, dermatitis are not very pleasant phenomena. When you get covered in itchy spots, you want to quickly find a miracle cure to get rid of them. For some, Flucinar was prescribed by a doctor, for others it was recommended to them in a pharmacy, for others they only heard about it, in this article we will look at this drug in more detail.

General information

Description:

• It is a drug from the group of glucocorticosteroids used to treat skin rashes.
• It contains fluocinolone acetonide.
• This medicine is produced in Poland.

Pharmakinetics:

• "Flucinar" penetrates the skin quite easily and quickly and accumulates in its stratum corneum.
• It can be slightly absorbed into the blood, then transformed in the liver and excreted unbound in the urine and, to a small extent, in the bile.
• Absorption is best when applied to the face or applied as a bandage.
• Absorption occurs faster if you use “flucinar” very often or apply it to large areas of the skin.
• The drug is absorbed better in children than in adults.

Pharmacodynamics

Under the influence of the drug, the sensitivity of the skin to manifestations decreases.

Pharmacology

The drug is a synthetically synthesized glucocorticosteroid.

According to the observations of doctors, “flucinar”, when used by young people, is absorbed into the skin faster than when used by older people. This fact is explained by the fact that young skin contains more lipids.

Main properties of the drug:

• Anti-inflammatory.
• Antipruritic.
• Antiallergic.
• Antiexudative.

Compound

Ointment

Gel

In what forms is it available?

There are the following forms: in the form of a gel and in the form of an ointment.

Price

The price varies from 200 to 250 rubles.

Best before date

The gel can be stored for 3 years, the ointment can be stored a little longer, 5 years.

How it is dispensed in pharmacies and storage conditions

Available without a prescription. Flucinar should be stored at a temperature not exceeding 25°C.

Interaction with other drugs:

Flucinar has some immunosuppressive effects, so vaccination is not recommended while using this medication.

Indications. Contraindications. Dosage

Indications for use

Skin inflammations, including:

• Neurodermatitis.
• Eczema.
• Psoriasis.
• Lichen.
• Dermatitis.

Contraindications (when the drug should not be used):

• Skin diseases of a bacterial, fungal, viral, tumor nature.
• Acne.
• Hypersensitivity.

How to use and in what quantities:

• Apply externally.
• A small portion of the drug should be applied to the affected area, lightly rubbing, no more than once or twice a day.
• For psoriasis, a bandage can be used.
• Treatment should continue for no more than one to two weeks.
• When used with caution, the duration of treatment should not exceed one week.
• For children, it is recommended to use this drug only from two years of age.
• The gel is more suitable for treating the surface of the skin covered with hair, as well as when the components of the ointment base are poorly tolerated.

Exceeding the dose:

• Cases of flucinar overdose are rare.
• With long-term use of Flucinar, undesirable effects may appear, which disappear when the drug is discontinued.

Side effects and special instructions

Side effects

With short-term use, it usually does not cause side effects. Side effects develop more often with prolonged use.

Possible undesirable manifestations:

• Vascular purpura.
• Acne.
• Loss of skin color.
• Hair growth or baldness.
• Folliculitis.
• Swelling.
• Dry skin.
• Changes subcutaneous tissue.
• Skin atrophy.
• Hives.
• Perioral dermatitis.

• Reduced epidermal growth.
• Rash.
• Immune suppression.
• Increased blood pressure.
• Secondary skin infections.

If the drug is applied to the skin of the eyelids, glaucoma or glaucoma may occur.

Special instructions:

• It is not recommended to use flucinar during pregnancy; in the first trimester it is better to avoid it altogether, but in the second and third trimesters it can be used if the risk to the unborn child is less than the expected benefit of the drug.
• During breastfeeding, the drug is prescribed with caution, for a short period.
• It is not recommended to apply the drug to the skin of the mammary glands themselves.
• Flucinar is prescribed with caution to elderly patients.

Analogs

Analogues of the drug:

• "Ezacinone".
• "Flucourt".
• "Sinalar".
• "Sinoderm".

“Sinaflan” is an analogue of “flucinar” from a Russian manufacturer, its price is slightly less, from 20 to 70 rubles, the active substance is similar. The price of other drugs exceeds the price of flucinar.

Some facts about the product:

Instructions for use

Price in online pharmacy website: from 272

Some facts

The drug Flucinar is a synthetic glucocorticosteroid for external use. Its activity is characterized as anti-inflammatory, anti-allergic and anti-scabies. Also claimed is an action aimed at eliminating increased vascular permeability and the release of fluid (exudate) into the tissue, which is observed in various inflammatory reactions.

Conditions for dispensing from pharmacies

Dispensing from pharmacies is carried out only according to indications and a prescribed prescription from the attending physician.

Storage conditions and periods

Release form and composition

A jelly-like transparent substance without a specific color with a subtle ethanol odor is placed in an aluminum tube with a tightly screwed plastic cap. The cardboard box contains a tube and instructions for use. The main active ingredient is fluocinolone acetonide. The composition is supplemented by such active elements as ethanol, propylene glycol, disodium ethylenediaminetetraacetic acid/edta, lemon acid, preservative E218, para-hydroxybenzoic acid propyl ester, carbopol, trieanolamine salicylate, purified water.

Pharmacological properties

Any inflammation of the skin is called dermatitis. In acute dermatitis, the disease begins suddenly, its symptoms are bright and expressive, but, most often, they are highly treatable. If therapy was not provided or was provided, but to a lesser extent than necessary, then with this outcome acute dermatitis threatens to take chronic form. Often, some forms of dermatitis are very similar in their symptoms to psoriasis. This disease is also classified as dermatological, is non-infectious and is characterized by the formation of a reddish-pink rash and severe peeling, since cell division of the skin under these circumstances occurs almost thirty times faster. Since the body’s immune system is also involved in this pathological situation, the defense cells are turned against their own cells, resulting in inflammation of a chronic nature in the affected area.

Flucinar copes well with such manifestations. Its active component belongs to the group medicinal substances synthetic (artificial) origin, which belong to a subgroup of hormones from the adrenal cortex. When applied externally, the drug is well absorbed through the skin. The provision of a characteristic antiphlogistic effect occurs due to the suppression of mediators of allergic and inflammatory processes and derivatives of polyunsaturated fatty acids. The glucocorticoid blocks polyunsaturated fatty acid and reduces the activity of Lipoprotein-associated phospholipase A 2, thereby significantly reducing the increased permeability of blood vessels due to their narrowing. Among other things, it significantly reduces the formation of new cells, due to which the tissue volume increases. Affects carbohydrate, fat, mineral and protein metabolism in the body. Affects a noticeable increase in the sugar (glucose) content in the blood serum. fluocinolone acetonide takes on the task of regulation immune system, functions of the kidneys, circulatory system, metabolism bone tissue and activity of the central nervous system.

Indications for use

It is acceptable to use the gel form of Flucinar in the treatment of diseases such as:

• a non-contagious pathology that is accompanied by a feeling of itching and the appearance of ulcers, blisters and scales on the skin, also known as eczema;
• types of dermatitis caused by a hereditary predisposition to allergic manifestations;
• lichen, in which local skin lesions are chronic and recurrent;
• dermatitis, which is caused by skin inflammation due to exposure to allergic or toxic-allergic substances that penetrate the skin directly through the patient’s bloodstream;
• dermatitis type, in which skin areas with developed sebaceous glands;
• different nature diseases united by one clinical symptom: areas of skin like blisters that resemble a nettle burn;
• dermatosis with scabies, the main indicators of a rash in which are nodules with small bubbles in the center;
• inflammatory process in the folds of the skin, the development of which occurs when skin surfaces come into contact and the action of skin secretions and other body secretions that cause irritation;
• the process of inflammation on the skin and mucous membranes with various elements present simultaneously, such as papules, vesicles and erythema;
• exudative form of psoriasis;
• lichen, the only sign of which is a red papule;
• cutaneous autoimmune disease, in which foci of erythema appear in dense scales and atrophic zones;
• blockage of the sweat glands and the formation of many blisters on the hands, which constantly itch;
• development of the inflammatory process in the external ear canal;
• redness and swelling of the skin due to a burn;
• bites of various insects.

Method and features of application

Flucinar gel should be applied externally. After wiping the intended application area with a cotton swab and antiseptic liquid, squeeze out a small column of Flucinar and cover a small area with this dosage and rub in lightly. The daily dose of the drug is determined by application two to four times a day. If there is a forced need for a bandage that completely blocks the access of air to the wound, then the manufacturer’s instructions prescribe its application to the affected surface for a maximum period of 4 days. Applying a dosage of medication under the bandage that exceeds 2 grams per day is unacceptable. During therapy, you should wear loose clothing made from natural materials.

Side effects

Associated negative consequences of Flucinar include:

• irritating feeling of heat on the surface of the body;
• itchy skin;
• acne;
• skin atrophy in the form of narrow wavy stripes of different widths;
• dry skin surface;
• infectious lesion of the hair follicle of the middle and deep sections, leading to its purulent inflammation;
• excess growth of dark, hard and long hair in women according to the male type;
• dilation of small skin vessels in the form of a spider vein or asterisk;
• primary diathesis of hemorrhagic type;
• skin pigmentation disorder;
• loss of existing hair on the head and disruption of the process of new hair growth;
• weakness of the body and the entire immune system.

When applied to large areas, there is a possibility of systemic manifestations of adrenal insufficiency, inflammation of the gastric mucosa, diabetes mellitus, and slowing down of reorientation processes.

Overdose

An overdose of the drug may lead to symptoms and/or worsening side symptoms.

Contraindications

Contraindications to the use of Flucinar are:

• manifestations on the skin of an STD such as syphilis;
• chronic diseases caused by the introduction of the microbacterium tuberculosis;
• diaper dermatitis;
• rosacea;
• itching of the external genitalia, perineum and anus;
• deep inflamed defects in the epithelium of the skin or mucous membrane and basement membrane;
• chickenpox;
• any types of herpes;
• infection caused by radiant fungi;
• any fungal infection of a person;
• ulcers of trophic origin on the legs associated with varicose veins;
• erosion and peptic ulcers gastrointestinal tract;
• benign or malignant tumor pathologies of the skin;
• pediatric age up to two years;
• puberty in girls.

Drug interactions

There is compatibility of Flucinar with antibacterial drugs. May reduce the effectiveness of diuretics and antihypertensives.

Pregnancy and breastfeeding

The manufacturer's annotation contains instructions prohibiting the use of Flucinar by pregnant women or during breastfeeding.

Alcohol compatibility

There is no clinical evidence for the safe combination of Flucinar with alcoholic beverages. Therefore, alcohol is contraindicated during therapy.

Instructions for medical use

medicine

FLUCINAR ®

Tradename

Flucinar ®

International generic name

Fluocinolone acetonide

Dosage form

Gel 0.025%

Compound

1 g of gel contains

active substance- fluocinolone acetonide 0.25 mg

Excipients: propylene glycol, ethanol, citric acid, disodium edetate, methyl parahydroxybenzoate, propyl parahydroxybenzoate, carbomer 980 (high molecular weight carboxypolymethylene), trolamine, purified water to 1.0 g

Description

Colorless transparent gel with slight opalescence and the smell of ethyl alcohol.

Pharmacotherapeutic group

Glucocorticosteroids for local treatment skin diseases. Active glucocorticosteroids ( group III). Fluocinolone acetonide

Code ATX D07AC 04

Pharmacodynamic properties

Pharmacokinetics

Fluocinolone acetonide when applied topically to the skin, it easily penetrates the stratum corneum of the skin, where it accumulates; its presence can be confirmed even 15 days after external use. Does not biotransform in the skin. After absorption into the body, it is mainly biotransformed in the liver. It is excreted in the urine and, in smaller quantities, in bile, mainly in the form of compounds with glucuronic acid and in small amounts unchanged.

The absorption of fluocinolone acetonide through the skin increases after application to delicate skin in the folds or facial skin, to skin with damaged epidermis or damaged by an inflammatory process. Application of an occlusive dressing, causing an increase temperature and humidity of the skin also increases the absorption of fluocinolone acetonide. In addition, absorption increases with frequent application of the drug or use over a large surface of the skin; absorption through the skin is more pronounced in young people than in older people.

Pharmacodynamics

Flucinar ® gel - is a highly active synthetic glucocorticosteroid for external use on the skin. Used in the form of a 0.025% gel, the drug exhibits anti-inflammatory, antipruritic, antiallergic and vasoconstrictor effects. It has lipophilic properties and penetrates the skin into the body. Already after using 2 g of gel, a decrease in the secretion of adrenocorticotropic hormone (ACTH) by the pituitary gland may occur through inhibition of the pituitary-adrenal system.

The mechanism of the anti-inflammatory action of fluocinolone acetonide has not been fully studied, and it is generally accepted that this medicinal product reduces inflammatory processes by inhibiting the production of prostaglandins and leukotrienes as a result of inhibiting the activity of phospholipase A-2 and reducing the release of arachidonic acid from phospholipids cell membranes. It also exhibits an antiallergic effect by inhibiting the development of local allergic reactions. As a result of local vasoconstrictive action, it reduces exudative reactions. Reduces protein synthesis and collagen deposition. Accelerates the breakdown of proteins in the skin and weakens proliferative processes.

Indications for use

Flucinar ® The gel is used externally in the first phase of treatment (before ointment) for acute and severe, non-infected, dry dermatitis that responds to treatment with glucocorticosteroids and occurs with persistent itching or hyperkeratosis.

allergic contact dermatitis

atopic dermatitis

urticarial lichen

allergic contact eczema

erythema multiforme

lupus erythematosus

advanced form of psoriasis, psoriasis of the scalp

lichen planus

Directions for use and doses

At the beginning of treatment, the gel is used 2-3 times a day, and then after resolution of the acute inflammatory condition, no more than 1-2 times a day. Treatment should not be carried out without interruption for more than 2 weeks. The gel should be applied in a thin layer to the affected skin surface. The gel should not be used under an occlusive dressing. If dressing is necessary, a breathable dressing should be used. Do not use on the face for more than 1 week. Do not use more than one tube per week.

In children over 2 years of age, use with extreme caution only if necessary, once a day, on a small surface of the skin. Do not use on facial skin.

Side effects

Atrophic dermatitis and the appearance of stretch marks

Post-steroid purpura

Depigmentation or skin pigmentation

Telangiectasia

Perioral dermatitis

Folliculitis

Hypertrichosis or baldness

Rarely:

Urticaria or maculopapular rash, or exacerbation of existing changes.

Topical application to the skin in the eyelid area may lead to the formation of glaucoma or cataracts.

The drug under an occlusive dressing, taking into account increased absorption, can cause a systemic effect, manifested by the onset of edema, arterial hypertension, decreased immunity.

Contraindications

Hypersensitivity to the components of the drug, viral, bacterial and fungal infections skin

Chicken pox

Acne vulgaris and rosacea

Perioral dermatitis

Conditions after vaccination

First trimester of pregnancy

Children under 2 years old

Drug interactions

There are no known cases of interactions with topical use of glucocorticosteroids. During treatment with the drug, vaccinations against smallpox and other types of immunization should not be performed, due to the risk of immunological deficiency. Flucinar ® The gel may increase the effect of immunosuppressive drugs and reduce the effect of immunostimulant drugs.

Influenced local application fluocinolone acetonide, it is possible to reduce the secretion of adrenocorticotropic hormone (ACTH) from the pituitary gland by inhibiting the pituitary-adrenal system, which leads to a decrease in the concentration of cortisol in the blood and the occurrence of iatrogenic hyperadrenocorticism syndrome, the intensity of which decreases when treatment is stopped.

Use on the eyelids or on the skin in the eyelid area should be avoided in persons with closed-angle and open-angle glaucoma, as well as in persons with cataracts, given the possibility of increased symptoms of the disease.

On the skin of the face and groin area, use only in cases of special need, taking into account increased absorption and high risk development side effects, even after short-term use (telangiectasia, dermatitis perioralis).

Use with caution in existing conditions of subcutaneous tissue atrophy, especially in the elderly. If an infection develops at the site of application of the gel, it is necessary to carry out additional antibacterial or antifungal therapy. If symptoms of infection remain, you should stop using the gel until the infection is cured.

Pregnancy and lactation

Flucinar ® the gel can be used in pregnant women in the second and third trimesters only for a short time, on a small surface of the skin, if the expected benefit may outweigh the potential risk to the fetus.

Impact on the ability to drive vehicles and service potentially dangerous devices

The drug does not limit psychomotor activity and does not affect the ability to drive vehicles or maintain moving machinery.

Overdose

With prolonged use on a large surface of the skin, overdose symptoms may occur, manifested high pressure, edema, hyperglycemia and immunosuppressive effect, and in severe cases the development of Cushing's syndrome. Symptoms of overdose disappear after discontinuation of the drug and use of therapy with a lower content of glucocorticosteroids.

Release form and packaging

15 g of the drug are placed in aluminum tubes with a varnished inner surface, with plastic screw caps.

One tube, along with instructions for medical use in the state and Russian languages, is placed in a cardboard pack.

Storage conditions

Store at a temperature not exceeding 25°C. Do not freeze.

Keep out of the reach of children!

Shelf life

Do not use after the expiration date

Conditions for dispensing from pharmacies

On prescription

Manufacturer

Pharmaceutical plant Jelfa A.O.

ul. W.Pola 21, 58-500 Jelenia Gora, Poland

Registration Certificate Holder

LLC "Valeant", Russia

Address of the organization that accepts claims from consumers regarding product quality on the territory of the Republic of Kazakhstan

Representative office of Valeant LLC in the Republic of Kazakhstan

Kazakhstan, 050059, Almaty, Al-Farabi Avenue, 17, Nurly-Tau Business Center Block 4B, office 1104

Phone + 7 727 3 111 516, fax +7 727 3 111 517

Email: [email protected]

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Flucinar is drug, intended for external use. The product has a pronounced anti-edematous, anti-inflammatory and anti-allergic effect. Is Flucinar ointment hormonal or not? The drug belongs to the group of synthetic glucocorticosteroids, that is, it is a hormonal drug.

Composition of Flucinar ointment

The drug contains fluocinolone acetonide in a ratio of 1 gram/0.25 mg. The drug is sold in aluminum tubes of 15 g. Among the excipients included in the ointment, it is worth highlighting the following components:

• lemon acid;
• propylene glycol;
• disodium edetate;
• ethanol;
• methyl parahydroxybenzoate;
• propyl parahydroxybenzoate;
• carbomer 980;
• trolamine;
• purified water.

The drug in the form of a cream contains such additional substances as:

• lanolin anhydrous;
• propylene glycol;
• petrolatum;
• lemon acid.

An annotation is attached to each package of Flucinar.

What is it used for: indications for use

Flucinar is a drug, so its use should be approached with care and caution. It is recommended to use Flucinar ointment for the treatment of acute dermatitis with a bacterial basis. According to reviews of the drug, Flucinar ointment helps get rid of severe disease, accompanied by severe itching and severe hyperkeratosis. According to the instructions, the drug is prescribed for:

• contact eczema;
• psoriasis;
• lichen planus and lichen rosea in humans;
• atopic dermatitis;
• seborrheic dermatitis.

Instructions for use Flucinar

Flucinar ointment is a medicine, the instructions for which indicate that the drug must be applied to damaged areas of the epidermis in a very thin layer. If there are pronounced signs of eczema, the drug is applied under a gauze bandage. This method of using funds involves regular dressings. The maximum duration of use of Flucinar is 14 days. One course of treatment involves the use of no more than 2 tubes of the drug, that is, 30 mg of the medicinal composition.

The drug is allowed for use in pediatric practice, but only with strict indications and recommendations from a professional attending physician. The ointment is suitable for the treatment of children over 2 years of age. In this case, the product is applied once a day to the affected area of ​​the body. The drug is contraindicated for lubricating skin folds and the face.

Contraindications and side effects

The use of Flucinar is contraindicated if the patient has hypersensitivity to the main active ingredient of the drug or one of the additional components included in its composition. Otherwise, after using the ointment, a person may experience allergic reaction in the form of hives, itching and redness. Flucinar ointment should not be used for tuberculosis of the skin, manifestations of syphilis, large psoriatic plaques on the body, rosacea, infectious skin lesions caused by viral, bacterial or fungal pathogens.

The drug is contraindicated for diaper dermatitis in newborns, severe itching of the anus, ulcers and wounds on the skin. The ointment should not be used for gastrointestinal ulcers, the presence of tumors and precancerous skin conditions, for women during pregnancy and breastfeeding, as well as children under 2 years of age. Doctors recommend using the product with extreme caution for young girls during puberty.

As a result of improper use of Flucinar ointment, side effects may occur. Only in the most extreme cases, burning and itching may develop on the skin, steroid acne, dry areas of the epidermis, and folliculitis may appear. If you do not stop using the product in time, there will be a risk of developing skin atrophy, active hair loss, and the appearance of pronounced age spots. Under unfavorable circumstances, in rare cases, after using the ointment, the patient may experience an inflammatory process that may worsen chronic illness, infection spread, develop acute symptoms gastritis and steroid ulcers and other chronic diseases.

special instructions

Flucinar ointment should not be used for longer than 14 days. Otherwise, the risk of developing unpleasant side effects. If the patient experiences symptoms of infection during treatment with the ointment, consult a doctor immediately. In such cases, antifungal and antibacterial medications are prescribed.

If after 14 days Flucinar has not produced any results, its use is discontinued. Application of the drug to the skin of the eyelids is contraindicated in the presence of cataracts or glaucoma - as a result, the severity of the symptoms of the disease will increase.

To date, there is no clear and reliable data on the degree of penetration of the active ingredients of the drug into breast milk, therefore, during breastfeeding, experts strongly recommend using the ointment extremely carefully in short courses.

Price

The cost of the product differs in different pharmacy chains and online stores. The final cost of the medicine is influenced by various factors, which include the country of origin and the seller’s individual approach to determining the price of his product. On average in Russia the cost of ointment is 168 rubles. In Moscow, a 15 g package of Flucinar costs 175 rubles.

Analogs of Flucinar ointment

The drug Flucinar has analogues containing identical active ingredients:

• Sinalar
• Sinaflan
• Sinaflan liniment
• Sinaflana liniment 0.025%
• Sinaflan ointment 0.025%
• Sinoderm Flucort
• Flukort C
• Fluocinolone acetonide
• Ezacinone

In modern pharmacies there are many other analogues of the drug in question, which have a similar effect. These include the drugs Celestoderm, Advantan, Betliben and others. Analogues and synonyms of Flucinar ointment are characterized by the same indications and contraindications.

Reviews

Irina, 35 years old : The last time I used the ointment was during the treatment of manifestations of psoriasis. My doctor prescribed the drug Flucinar to me. It cleaned my skin perfectly, itching and discomfort disappeared – I was completely delighted. Currently, I am trying to monitor my diet so as not to provoke the development of the disease again.

Ekaterina, 28 years old : I used to use synaflant, which not only did not help, but also caused ugly acne to appear on my face and body. Thanks to Flucinar, I quickly cleared my skin and relieved swelling. From my own experience, I can say that it is better to choose not cheap, but high-quality drugs, so as not to harm your health even more.

Elena, 30 years old: I made my unconditional choice towards Flucinar. This is an absolutely safe and, most importantly, working remedy, the effect of which is manifested within a short time after you start using it. Some kind of rash constantly appears on my skin, so I always have Flucinar in my cosmetic bag.

(FLUCINAR)

Registration number: P N014396/02-100610

Trade name of the drug: Flucinar ®

International Nonproprietary Name (INN): fluocinolone acetonide

Dosage form: gel for external use

Compound:
1 g of gel contains
Active ingredients : fluocinolone acetonide 0.25 mg.
Excipients : propylene glycol, ethanol, disodium edetate, citric acid, methyl parahydroxybenzoate, propyl parahydroxybenzoate, carbomer 980, trolamine, purified water.

Description:
Colorless, transparent jelly-like mass with a faint odor of ethanol.

Pharmacotherapeutic group: glucocorticosteroid for topical use
ATX code D07AC04

Pharmacological properties
Pharmacodynamics
It has anti-inflammatory, antipruritic, antiexudative and antiallergic effects.
Inhibits the release of inflammatory mediators. When exposed to the skin, the marginal accumulation of neutrophils is prevented, which leads to a decrease in inflammatory exudate and cytokine production; inhibition of macrophage migration, reduction of infiltration and granulation processes.

Pharmacokinetics
Fluocinolone acetonide easily penetrates the skin through the stratum corneum. It does not undergo biotransformation in the skin and accumulates in the stratum corneum. It is detected in the skin even 15 days after its topical application. When fluocinolone is used externally, acetonide may be absorbed to a small extent and cause general symptoms. After absorption, it is metabolized mainly in the liver. In the form of compounds with glucuronic acid and in a small amount in an unbound form, it is excreted through the kidneys and slightly with bile.

Indications for use
Inflammatory diseases skins amenable to glucocorticosteroid therapy:

• atopic dermatitis;
• eczema;
• seborrheic dermatitis;
• psoriasis, including the scalp;
• exudative erythema multiforme;
• lichen planus.

Contraindications
Hypersensitivity, skin manifestations of syphilis, skin tuberculosis, diaper rash, rosacea, extensive psoriatic plaques, anogenital itching;
skin infections caused by bacteria, viruses, fungi; wound damage to the skin, ulcers; erosive and ulcerative lesions of the gastrointestinal tract;
tumors and precancerous skin conditions; pregnancy, lactation period, childhood(up to 2 years).
Carefully
In girls during puberty.

Directions for use and doses
Externally.
A small amount of the drug is applied to the skin, previously wiped with a swab moistened with an antiseptic liquid, 2-4 times a day and lightly rubbed. The duration of treatment depends on the nature of the disease and is usually 5-10 days. If necessary, an occlusive dressing can be applied. It is not allowed to use more than 2 g/day under a bandage.
Flucinar ® in the form of a gel is indicated in the first phase of treatment (before ointment) and for the treatment of diseases of the scalp, as well as in that category of patients who do not tolerate the drug well due to the ointment base.
The gel form makes it possible to apply it in small quantities, and therefore smaller doses of the drug over a larger surface of the skin.

Side effect
Burning, itching, steroid acne, stretch marks, dry skin, folliculitis. With long-term use - skin atrophy, local hirsutism, hypertrichosis, telangiectasia, purpura, skin pigmentation disorders, alopecia, especially in women, secondary immunodeficiency (exacerbation of chronic infectious diseases, generalization of the infectious process, development of opportunistic infections); when applied to large surfaces, systemic manifestations are possible (gastritis, “steroid” gastric ulcer, adrenal insufficiency, Itsenko-Cushing syndrome, “steroid” diabetes, slowing down reparative processes).

Overdose
Overdose for external use is very rare.
Symptoms: itching and burning of the skin at the site of application of the drug, hyperglycemia, glucosuria, Itsenko-Cushing syndrome.
Treatment: symptomatic with gradual withdrawal of the drug.

Interaction with other drugs
Compatible with antimicrobial agents.
Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs medicines, K+ drugs. Diuretic drugs (except potassium-sparing drugs) increase the risk of hypokalemia.
During treatment with glucocorticosteroids, vaccinations and immunizations should not be performed due to the immunosuppressive effect of the drug.

special instructions
If secondary infections occur at the site of application of the drug, an antibacterial or antifungal treatment.
Use Flucinar ® with extreme caution on the skin of the face, since absorption of the drug increases and the possibility of side effects increases.
Use with caution in persons with existing atrophic skin changes, especially in the elderly.
It is recommended to mow loose clothing during treatment.

Impact on ability to manage vehicle and maintenance of moving mechanisms.
The drug does not limit psychophysical activity, the ability to drive a vehicle or operate moving machinery.

Release form
Gel for external use 0.025%.
15 g each in aluminum tubes with lacquered lithographed inside.
The tube with instructions for use is placed in a lithographed cardboard box.

Best before date
3 years.
Do not use after expiration date.

Storage conditions
Store at a temperature not exceeding 25°C. Do not freeze.
Keep out of the reach of children.

Conditions of release from pharmacies
List B. Without a prescription.

MANUFACTURER NAME AND ADDRESS
Pharmaceutical plant Elfa A.O.
st. W. Polya 21, Jelenia Gora, Poland, 58-500

Send consumer complaints to the Representative Office
JSC Farmzavod Elfa (Poland), Moscow:
Russia 119049, Moscow, Koroviy Val, 7, building 1, office 80