Thiogamma dropper instructions for use. Thiogamma: instructions for use and what it is needed for, price, reviews, analogues. Conditions, shelf life

Thiogamma tablets – medicine, which has metabolic and antioxidant effects. International generic name(INN) active substance: thioctic or alpha lipoic acid. The medicine from the German pharmacological company is actively used in medicine as part of complex therapy diabetes, polyneuropathy, oxidative stress. In cosmetology, Thiogamma has been used to smooth out wrinkles, improve complexion, and treat skin rashes.

Composition and dosage forms

Main active substance Thiogamma is alpha-lipoic (thioctic) acid, the content of which is the same in all forms of release - 600 mg. In addition to the main component, the medication contains additional and formative compounds: cellulose, lactose, silicon dioxide, talc.

Thiogamma 600 mg is available in 3 dosage forms.

Pills

Vegetable-coated tablets are used for oral administration of medication in situations where slow saturation of the body with thioctic acid is required. One package contains 30 or 60 pieces.

Solution for infusion

One 50 ml bottle contains 600 mg of lipoic acid; macrogol and meglumine are added to improve the colloidal properties of the liquid. The product is used for infusion with a dropper, which allows you to quickly achieve a high concentration of the substance in the blood.

Concentrate for the preparation of infusion solution

This liquid form of Thiogamma is sold in 20 ml bottles that contain 600 mg of the active ingredient. When used, the medicine is diluted with an isotonic sodium chloride solution to the recommended concentration of thioctic acid.

The solution and concentrate are intended for intravenous administration, and can only be used in medical institutions under constant medical supervision. Therefore, in further analysis of indications, contraindications, side effects and annotations for the drug we will talk about the solid dosage form - tablets.

Pharmacological features

Alpha lipoic acid is a vitamin-like substance that exhibits antioxidant properties and acts as a coenzyme in many metabolic processes. The compound can be synthesized in the body in decarboxylation reactions, but under certain conditions pathological conditions this process is disrupted. Acid reduces concentration harmful products glycation in diabetes mellitus, improves trophism of nerve fibers. The substance can increase the level of the endogenous antioxidant glutathione.

After oral administration of the drug Thiogamma, the active component is absorbed into the bloodstream through the mucous membrane of the stomach and upper parts small intestine. The bioavailability of the drug is 30-35%, the maximum content in the blood is detected an hour after administration. The main part of thioctic acid and its metabolic products is excreted by the kidneys.

When is the drug prescribed?

The main indications for prescribing the drug for medical purposes:

1. Diabetic polyneuropathy. For diabetes, Thiogamma can reduce the concentration of glucose in the blood and increase the sensitivity of peripheral receptors to insulin. By improving the rheological properties of plasma, the product improves blood circulation in small vessels and accelerates the processes of nerve impulse transmission. Alpha-lipoic acid is also used to prevent the formation of diabetic foot.
2. Alcoholic neuropathy. The antioxidant capabilities of alpha lipoic acid can reduce the toxic effects of ethanol on peripheral neurons. The drug helps to cope with paresthesia, pain and burning in the extremities resulting from dysfunction of the peripheral nerves.

Thiogamma is actively used in the cosmetology field, since it helps in the treatment of skin diseases, reducing the severity age-related changes facial skin. The product can also be used to increase hair thickness and accelerate hair growth.

For prophylactic purposes, the drug can be used by people with incipient metabolic syndrome to normalize glucose levels and prevent specific cellular damage. The ability of Alpha-lipoic acid to accelerate metabolic processes is actively used in dietetics: supplements are prescribed to people with overweight to “start” metabolism and facilitate the process of weight loss.

Thioctic acid for weight loss - review from a nutritionist (video):

Contraindications

Thioctic acid Thiogamma is not prescribed in the following situations:

• in case of individual hypersensitization to the components of the drug;
• V acute period allergic reactions;
• with congenital galactose intolerance;
• with deficiency of disaccharidase enzymes (lactase).

Also absolute contraindication the use of the drug Thiogamma is the entire period of bearing a child and breastfeeding. The medicine is not prescribed to children under 18 years of age, since its clinical safety and effectiveness in childhood have not been established.

How to take it correctly

Thiogamma, according to the instructions for use, adults are prescribed 1 tablet per day, which is equivalent to 600 mg of the active substance. The product is taken 30-40 minutes before meals, always washed down with a sufficient amount of clean water. The standard course of taking the drug is 1-2 months, depending on the disease and the severity of the patient’s condition. If necessary, the drug can be repeated up to 3 times a year.

Thioctic acid can accelerate the reactions of lipid and carbohydrate metabolism, so it can be used for weight loss. Nutritionists recommend drinking Thiogamma 600 mg once a day, half an hour before breakfast. Duration of use – 30 days. Lipoic acid has a good effect on the condition of the skin and hair, but in this case, a liquid form of the product is used for treatment, which is applied to clean skin as part of tonics and lotions.

Special cases

Prescription of the drug Thiogamma in people with diabetes mellitus should be accompanied by constant monitoring of blood sugar levels, especially in the first week of use. Thioctic acid has a pronounced hypoglycemic effect, so it may be necessary to recalculate the dosages of insulin and oral hypoglycemic drugs. During the course of treatment with Thiogamma 600 mg, you should stop drinking alcohol, since alcohol can aggravate the manifestations of neuropathy. The use of the drug in tablet form is not recommended for patients with congenital deficiency of disaccharidases (glucose-galactose syndrome, fructose intolerance).

Side effects

Side effects when taking Thiogamma orally are quite rare. At the beginning of the course, there may be minor dyspeptic disorders: nausea, abdominal discomfort, impaired frequency and consistency of stool, changes in taste preferences. Sensitized people sometimes develop allergic reactions skin type: itching and redness, rashes, exacerbations atopic dermatitis and eczema.

When drinking alcohol together with the drug Thiogamma, an increase in the manifestations of neuropathy is observed: paresthesia in the limbs, pain, tingling and burning. Patients with metabolic syndrome may experience symptoms of hypoglycemia (weakness, fainting, headache, dizziness), which are associated with increased glucose consumption and a critical decrease in its concentration in the blood.

Drug compatibility

The drug Thiogamma has the properties to change the pharmacokinetics and pharmacodynamics of other drugs:

1. The product reacts with metal ions (magnesium, iron, calcium) to form insoluble complexes, which reduces the bioavailability of lipoic acid.
2. Increases the hypoglycemic effects of oral medications and insulin.
3. Enhances the anti-inflammatory effects of corticosteroids.
4. When taking the drug Thiogamma 600 and cisplatin simultaneously, a decrease in the bioavailability and effectiveness of the latter is observed.

Signs of overdose

With the simultaneous use of high doses of Thiogamma (more than 10 g), an acute intoxication syndrome with deep depression of consciousness is observed, which can lead to death. When taking less than 10 g, signs of damage to the central nervous system by type of excitement, hyperkinesis, convulsions. There is also a change biochemical parameters blood: lactic acidosis, hypoglycemia. Damage to the blood system may occur - hemolysis of red blood cells, disseminated intravascular coagulation syndrome, aplastic anemia. There are no specific antidotes for an overdose of Thiogamma; symptomatic therapy is used.

Storage conditions

The tablet form of the drug Thiogamma must be stored at an air temperature of 16°C to 24°C and a relative humidity of no more than 60%. Direct contact should not be allowed sun rays. The shelf life of the drug is 5 years from the date of production.

Rules for dispensing from pharmacies

The medicine is prescription drug, and is sold only with a doctor's prescription. When going to the pharmacy, you need to take a prescription for Tiogamma 600 in Latin with you.

Pros and cons of the drug

Most patients who used Thiogamma tablets noted a significant improvement in their condition after 30 days of use. Among positive aspects the drug is called increased sensitivity of the limbs, reduced pain and discomfort in the legs. Patients with diabetes mellitus note improved blood supply to the distal parts lower limbs. Women highlight the positive effect of oral administration medicines for skin and hair: eliminating dryness and flaking, accelerating hair growth. Failure of some patients to comply with doctors' recommendations for taking Tiogamma causes negative reviews about the drug.

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Number of reviews: 1

from Svetlana on Thiogamma, 600 mg

Impressions from IVs with thiogamma

Advantages: Cramps disappear, joint mobility improves

Flaws: Burning in the stomach

Thiogamma ®

International nonproprietary name

Dosage form

Tablets, coated film-coated, 600 mg

Compound

One tablet contains

active substance - thioctic acid (alpha lipoic acid) 600.00 mg

Excipients - hypromellose (hydroxypropylmethylcellulose 5-6 mPa*s), colloidal anhydrous silicon dioxide, microcrystalline cellulose, lactose monohydrate, sodium carboxymethyl cellulose, talc, simethicone 30% emulsion, magnesium stearate

shell composition - macrogol 6000, hypromellose (hydroxypropyl methylcellulose 6 mPa*s), talc, sodium lauryl sulfate

Description

Capsule-shaped tablets, film-coated, light yellow color with white splashes, with a notch on both sides.

Farmacotherapy group

Other drugs for the treatment of diseases gastrointestinal tract(Gastrointestinal tract) and metabolic disorders. Various other drugs for the treatment of gastrointestinal and metabolic diseases. Thioctic acid.

ATX code A16AX01

Pharmacological properties

Pharmacokinetics

When taken orally, thioctic (alpha-lipoic) acid is rapidly absorbed into the body. The maximum plasma concentration of 4.44 ± 3.65 μg/ml occurred 0.31 ± 0.1 hours after oral administration of 600 mg of thioctic acid.

Alpha lipoic acid quickly spreads throughout tissues.

Alpha lipoic acid is metabolized primarily through ß-oxidation of the valeric acid side chain. The main metabolites were identified as bisnor-lipoic acid, tetran-lipoic acid and ß-hydroxybisnor-lipoic acid. The plasma half-life is rapid and is approximately 34.79 ± 8.74 minutes on the first day of dosing and 31.90 ± 7.47 minutes on the fourth day.

Excretion of the drug occurs primarily through the kidneys within 24 hours after administration.

Pharmacodynamics

Thioctic (alpha-lipoic) acid is an endogenous powerful antioxidant and acts as a coenzyme in the oxidative decarboxylation of alpha-keto acids.

Both alpha lipoic acid itself and the form of dihydro-lipoic acid (DHLA) it produces are capable of scavenging a wide range of free oxygen radicals. DHLA is capable of directly regenerating ascorbic acid from dehydroascorbic acid and directly regenerate vitamin E.

Thioctic acid helps reduce blood sugar and increase glycogen content in the liver, as well as overcome insulin resistance. Changes the concentration of pyruvic acid in the blood. Thioctic acid is close in pharmacological properties to B vitamins.

As a result of hyperglycemia caused by diabetes mellitus, glucose accumulates on proteins blood vessels and the formation of so-called “progressive glycosylated end products.” The results of this process are a decrease in endoneural blood flow and endoneurial hypoxia/ischemia associated with an increase in the level of free oxygen radicals that damage peripheral nerves. Depletion of antioxidants such as glutathione is also found in peripheral nerves.

Alpha lipoic acid acts in biochemical pathways through reducing the formation of advanced glycated end products, improving endoneurial blood flow, increasing physiological antioxidant levels of glutathione, and acting as an antioxidant against oxygen free radicals in peripheral nerves.

Thiogamma® is involved in the regulation of lipid and carbohydrate metabolism, stimulates cholesterol metabolism, improves liver function, and has hepatoprotective, hypolipidemic, hypocholesterolemic, hypoglycemic effects. Improves trophism of neurons.

Indications for use

as part of complex therapy for the treatment of peripheral (sensory-motor) diabetic polyneuropathy

Directions for use and doses

Daily dose of Thiogamma ® is 1 tablet per day approximately 30 minutes before the first meal. Take on an empty stomach, without chewing and with a small amount of water. Combination with food may reduce the absorption of thioctic acid. It is especially important to take the tablet half an hour before breakfast for patients with bowel movement disorders.

The duration of treatment is determined individually by the attending physician.

Since diabetic neuropathy is chronic disease, drug Thiogamma ® The tablets can be taken for a long time.

The main requirement in the treatment of diabetic polyneuropathy is optimal control of diabetes.

Side effects

nausea, vomiting, pain in the stomach and intestines, diarrhea

skin rash, urticaria, itching

dizziness, sweating, headache changes in visual perception due to decreased blood sugar levels

Rarely

taste disorder

Very rarely

Since treatment with the drug improves the absorption of glucose, a decrease in blood sugar levels is possible. At the same time, symptoms of hypoglycemia develop, such as dizziness, increased sweating, headache and changes in visual perception.

Contraindications

hypersensitivity to thioctic acid or any other component of this medicinal product

lactation period

hereditary fructose intolerance, Lapp-lactase enzyme deficiency, glucose-galactose malabsorption

children and teenagers up to 18 years of age

Drug interactions

There was a decrease in the effectiveness of cisplatin when prescribed simultaneously with Thiogamma ® . The drug should not be prescribed simultaneously with iron, magnesium, potassium supplements; the time interval between doses of these drugs should be at least 5 hours. Since Thiogamma ® taken 30 minutes before breakfast, it is advisable to take iron and magnesium supplements at lunchtime or in the evening.

The drug should not be taken simultaneously with dairy products due to their calcium content.

Since the hypoglycemic effect of insulin or oral antidiabetic agents may be enhanced, regular monitoring of blood sugar levels is recommended, especially at the beginning of Thiogamma therapy ® . To avoid symptoms of hypoglycemia, it is necessary to carefully monitor blood glucose levels; in some cases, it may be necessary to reduce the dose of insulin or oral antidiabetic agents.

special instructions

During treatment with the drug, the use of alcohol is contraindicated. Alcohol consumption is a significant risk factor in the progression of neuropathic clinical picture and may interfere positive result Thiogamma treatment ® . Patients with diabetic polyneuropathy are advised to avoid drinking alcohol. This recommendation should also be followed when stopping treatment.

Concomitant food intake significantly reduces the bioavailability of thioctic acid.

Pregnancy and lactation

Pregnant women should be treated with thioctic acid only after careful assessment of the appropriateness of use, taking into account the benefit/risk ratio and under strict medical supervision.

There is no data on the penetration of the drug into breast milk.

Impact on the ability to drive a vehicle and potentially dangerous mechanisms

Care should be taken when driving vehicles and potentially dangerous mechanisms, although no special warnings are required.

Overdose

Symptoms: nausea, vomiting, headache.

There have been cases of oral administration of the drug with suicidal intent in the dose range from 10 to 40 grams of alpha-lipoic acid simultaneously with alcohol intake, when serious intoxication occurred, sometimes with fatal. The clinical toxicological profile in this case may manifest as psychomotor irritability, clouding of consciousness and is usually associated with subsequent generalized seizures and the formation of lactic acidosis.

Cases of glypoglycemia, shock, acute skeletal muscle necrosis, hemolysis, disseminated intravascular coagulation (DIC), depression have been described. bone marrow and multi-damage to organs as a consequence of intoxication during high doses alpha lipoic acid.

Treatment: symptomatic, there is no specific antidote.

At the slightest suspicion of possible intoxication of alpha-lipoic acid (taking more than 10 tablets of 600 mg in adults or taking > 50 mg/kg body weight in children), immediate hospitalization with general therapeutic measures for detoxification (artificial induction of vomiting, gastric lavage, taking activated coal).

Treatment of generalized seizures, lactic acidosis and all other life-threatening consequences of intoxication should be carried out in accordance with the principles of modern intensive care for these symptoms. The benefit of hemodialysis, hemoperfusion, or filtration technology to accelerate the elimination of alpha-lipoic acid has not been convincingly demonstrated.

Release form and packaging

Various types of intoxication, side effects from alcohol addiction are treated differently. Many drugs are based on a lot of chemical components.

It is best to use medications made from natural raw materials. One such medicine is Thiogamma.

In this article we will look at why doctors prescribe Thiogamma, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Tiogamma can be read in the comments.

Composition and release form

Thiogamma is produced by the manufacturer in several dosage forms: in tablets, in the form of a solution for infusion and a concentrate for preparing an infusion solution.

The active ingredient of the drug is thioctic acid (in the form of meglumine salt):

• 1 tablet – 600 mg;
• 1 ml of solution – 12 mg;
• 1 ml of concentrate – 30 mg.

Clinical and pharmacological group: a drug that regulates lipid and carbohydrate metabolism.

Indications for use

The drug Thiogamma is used to treat alcoholic and diabetic polyneuropathy.

pharmachologic effect

The active ingredient of Thiogamma (Tiogamma-Turbo) is thioctic (alpha-lipoic) acid. Thioctic acid is produced in the body and serves as a coenzyme for the energy metabolism of alpha-keto acids through oxidative decarboxylation. Thioctic acid leads to a decrease in glucose levels in the blood serum and promotes the accumulation of glycogen in hepatocytes.

Thioctic acid regulates the metabolism of carbohydrates and fats, has a positive effect on cholesterol metabolism, and has a hepatoprotective effect, improving liver function. It has a beneficial effect on reparative processes in tissues and organs.

Instructions for use

According to the instructions for use, Thiogamma tablets are taken on an empty stomach, without chewing, with a small amount of liquid.

• The recommended dose is 1 tablet per day.

The duration of treatment is 30-60 days, depending on the severity of the disease. The course of treatment can be repeated 2-3 times a year.

Contraindications

The use of Thiogamma is prohibited in the following cases:

• gastritis, peptic ulcer;
• period of pregnancy, breastfeeding;
• children under 18 years of age;
• chronic alcoholism;
• acute diseases of cardio-vascular system, respiratory organs;
• violations cerebral circulation;
• individual galactose intolerance, lactase deficiency;
• the presence of individual intolerance to individual components of the drug (acquired or hereditary).

Side effects

Taking Thiogamma can cause the following side effects:

• Immunity: immediate hypersensitivity reactions - less than 1/10,000 people.
• Vascular system: petechiae on the skin and mucous membranes, a decrease in the number of platelets in the blood serum, inflammation of the veins due to blockage by a blood clot - less than 1/10,000 people.
• From the central nervous system: disturbance or change in taste sensations, convulsions, epileptic seizure;
• Digestive system - uncontrollable urge to empty the stomach, abdominal discomfort, diarrhea - less than 1/10,000 people.
• Other: local atopic manifestations - less than 1/10,000 people, vertigo, cephalalgia, impaired consciousness, hyperhidrosis - less than 1/10,000 people.

In patients with diabetes, especially at the beginning of drug therapy, blood glucose levels should be monitored. If necessary, doses of oral hypoglycemic agents and insulin are adjusted. If symptoms of hypoglycemia appear, Thiogamma should be discontinued immediately.

Analogues of Tiogamma

Structural analogues of the active substance:

• Alpha lipoic acid;
• Berlition 300;
• Berlition 600;
• Lipamide tablets;
• Lipoic acid;
• Lipothioxone;
• Neurolipon;
• Octolipen;
• Thioctacid 600;
• Thioctacid BV;
• Thiolepta;
• Thiolipon;
• Espa Lipon.

Attention: the use of analogues must be agreed with the attending physician.

Price

The average price of THIOGAMMA, tablets (600 mg) in pharmacies (Moscow) is 800 rubles. Solution for infusion 12 mg/ml 50 ml No. 10 bottles – 1,700 rubles.

α-lipoic (thioctic) acid is synthesized in the body and acts as a coenzyme in the oxidative decarboxylation of α-keto acids; plays an important role in the process of energy formation in the cell. Helps reduce blood glucose levels and increase the amount of glycogen in the liver. Deficiency or metabolic disorder of α-lipoic acid due to intoxication or excessive accumulation of certain breakdown products (for example, ketone bodies) leads to disruption of aerobic glycolysis. α-Lipoic acid can exist in two physiologically active forms (oxidized and reduced), which have antitoxic and antioxidant effects. α-Lipoic acid affects cholesterol metabolism, takes part in the regulation of lipid and carbohydrate metabolism, improves liver function due to its hepatoprotective, antioxidant and detoxification effects. In terms of pharmacological properties, α-lipoic acid is similar to B vitamins. It has a beneficial effect on tissue regeneration processes.
Pharmacokinetics. After oral administration, α-lipoic acid is rapidly and almost completely absorbed from the gastrointestinal tract. It is excreted by the kidneys, mainly in the form of metabolites. The formation of metabolites occurs due to side chain oxidation and conjugation. The half-life from serum is 10-20 minutes.

Indications for use of the drug Tiogamma

Prevention and treatment of diabetic polyneuropathy, alcoholic neuropathy, liver diseases (hepatitis, cirrhosis, fatty degeneration), intoxication (for example, mushrooms, heavy metal salts).

Use of the drug Thiogamma

Prescribed for adults. The tablets are taken orally whole with a sufficient amount of water. Daily dose- 1 tablet of Thiogamma, which corresponds to 600 mg of α-lipoic acid, which should be taken as a single dose approximately 30 minutes before the first meal. Duration of treatment is 1-4 months.
The tablet is swallowed whole with a sufficient amount of liquid, regardless of meals. In case of severe sensory impairment caused by diabetic polyneuropathy, it is advisable to begin treatment with parenteral administration of Tiogamma Turbo for infusion. In the future, you should continue taking Thiogamma tablets at a dose of 600 mg/day.
Concomitant food intake may slow down the absorption of the drug.
The drug is administered parenterally as an intravenous infusion in an isotonic solution of sodium chloride, at a dose of 600 mg/day. To do this, the contents of one ampoule (which corresponds to 600 mg of α-lipoic acid) are diluted in 50-250 ml of sodium chloride solution. IV administration should be carried out slowly - no faster than 50 mg of α-lipoic acid (which corresponds to 1.7 ml of solution for infusion) per minute, over 20-30 minutes. The prepared solution should be used immediately; when administering it, a light-protective case should be used.

Contraindications to the use of the drug Tiogamma

Hypersensitivity to α-lipoic acid or other components of the drug; hereditary galactose intolerance, lactase deficiency, malabsorption syndrome, that is, impaired absorption of glucose and galactose; period of pregnancy and lactation, childhood and adolescence (up to 18 years).
Due to insufficient clinical data, it is not recommended to use the drug during pregnancy and lactation, as well as in children and adolescents.
Severe liver and kidney dysfunction, acute and decompensated cardiac and respiratory failure, acute phase of myocardial infarction, acute cerebrovascular accident, dehydration, chronic alcoholism and other conditions that may contribute to the development of lactic acidosis (when using the injection form of the drug).

Side effects of the drug Thiogamma

Isolated reports of gastrointestinal disorders have been received: nausea, vomiting, pain in the stomach and intestines, diarrhea.
In some cases, allergic reactions: skin rash, urticarial rash and itching.
There have also been cases of symptoms similar to hypoglycemia with vertigo. excessive sweating, headache and blurred vision.
When taken orally, due to improved glucose utilization, a decrease in blood glucose levels may be noted. In isolated cases, dyspepsia and allergic skin reactions may develop.
When administered parenterally, the following side effects are possible:
from the nervous system and sensory organs: very rarely - convulsions, diplopia;
from the blood coagulation system: possible hemorrhagic rash (purpura), thrombophlebitis;
allergic reactions: urticaria or eczema at the injection site, systemic allergic reactions, including anaphylactic shock;
others: as with oral administration, a decrease in blood glucose levels may be observed due to improved glucose utilization. After rapid administration of the drug, a feeling of squeezing in the head and respiratory depression may occur, but these phenomena disappear spontaneously.

Special instructions for the use of the drug Tiogamma

During therapy with Thiogamma in patients with diabetes mellitus, due to improved glucose utilization, a decrease in blood glucose levels may be noted. Therefore, regular monitoring of blood glucose levels is necessary. In some cases, it is necessary to reduce the dose of hypoglycemic agents to prevent the development of hypoglycemia.
You should refrain from drinking alcohol, as the latter reduces the therapeutic activity of α-lipoic acid.
Use during pregnancy or breastfeeding. There is insufficient data regarding the use of the drug, therefore its use during pregnancy and lactation is not recommended.
Children. The effectiveness and safety of the drug in children have not been established.
Influence on reaction speed when driving vehicles or other mechanisms. There are no special precautions.

Interactions of the drug Thiogamma

in vitroα-lipoic acid reacts with ionic metal complexes, such as cisplatin, so the effectiveness of the latter may be reduced. α-lipoic acid forms poorly soluble complexes with sugar molecules, therefore its solution is incompatible with glucose solution, Ringer's solution and solutions that can react with SH groups or disulfide bonds.
α-Lipoic acid is a metal chelator and therefore cannot be used in conjunction with metals (for example, iron, magnesium preparations). If the total daily dose of Thiogamma is taken 30 minutes before the first meal, iron and magnesium supplements should be taken during lunch or in the evening.
When used simultaneously, α-lipoic acid enhances the effect of insulin and oral hypoglycemic agents.

Overdose of the drug Thiogamma, symptoms and treatment

Possible nausea, vomiting, headache. Treatment is symptomatic.

Storage conditions for the drug Thiogamma

Tablets: at a temperature of 15-25 °C.
solution for infusion: in a dark place at a temperature of 15-20 ° C.
Since α-lipoic acid is sensitive to light, ampoules should be stored in cartons until used.

List of pharmacies where you can buy Tiogamma:

• Saint Petersburg