Asparkam official instructions for use. Asparkam (injection solution). Synonyms of nosological groups

Compound

Composition per 1 tablet: active ingredients - potassium aspartate hemihydrate – 175.0 mg; magnesium aspartate tetrahydrate – 175.0 mg.

Pharmacotherapeutic group

Potassium and magnesium preparation

ATX code

pharmachologic effect

The most important intracellular cations of potassium and magnesium play a key role in the functioning of numerous enzymes, in the formation of bonds between macromolecules and intracellular structures, and in the mechanism of muscle contractility. The intracellular and extracellular ratio of potassium, calcium, sodium and magnesium ions affects myocardial contractility. Endogenous aspartate acts as a conductor of ions: it has a high affinity for cells, due to the slight dissociation of its salts, ions in the form of complex compounds penetrate into the cell. Magnesium aspartate and potassium aspartate improve myocardial metabolism. Magnesium/potassium deficiency predisposes to the development arterial hypertension, atherosclerosis coronary arteries, arrhythmias and metabolic changes in the myocardium.

Indications for use

To eliminate potassium and magnesium deficiency as part of combination therapy for various manifestations coronary disease heart (including myocardial infarction); chronic heart failure; heart rhythm disturbances (including arrhythmias caused by an overdose of cardiac glycosides).

Contraindications

Hypersensitivity to any of the components of the drug, acute and chronic renal failure, hyperkalemia, hypermagnesemia, Addison's disease, atrioventricular block I-III degrees, shock (including cardiogenic), arterial hypotension (arterial pressure less than 90 mm Hg), impaired amino acid metabolism, myasthenia gravis, hemolysis, acute metabolic acidosis, dehydration, age under 18 years (efficacy and safety have not been established), breastfeeding period.

Directions for use and doses

Before using the drug Asparkam, you should consult your doctor. The drug should be taken orally with a sufficient amount of water, without chewing. Take after meals, because... the acidic environment of the stomach reduces its effectiveness. Take 1 tablet 3 times a day. Maximum dose: 3 tablets per day. The duration of the course of treatment and repeated courses are as recommended by the doctor.

Release form

Tablets 175 mg + 175 mg. 10 tablets in a blister pack made of polyvinyl chloride film and printed varnished aluminum foil. 10, 20, 30, 50, 56, 60 or 100 tablets in polyethylene terephthalate or polypropylene jars for medicines, sealed with polyethylene lids high pressure with first opening control or polypropylene lids with a “push-turn” system or polyethylene lids low pressure with first opening control. One can or 1, 2, 3, 5, 6 or 10 blister packs along with instructions for use are placed in a cardboard package (pack).

INSTRUCTIONS
on the use of a medicinal product for medical use

Registration number:

Tradename.

Asparkam-Farmak.

Group name:

Dosage form.

Compound:

1 ml of solution contains anhydrous magnesium aspartate – 40 mg (3.37 mg magnesium), anhydrous potassium aspartate – 45.2 mg (10.33 mg potassium), aspartic acid – 74 mg, heavy magnesium oxide in terms of 100% substance – 5.59 mg, potassium hydroxide calculated as 100% substance – 14.82 mg;
Excipients: sorbitol – 50 mg, water for injection up to 1 ml.

Description. Transparent colorless or slightly yellowish liquid.

Pharmacotherapeutic group.

ATX code: A12СХ.

Pharmacological properties.

Indications for use.

Contraindications.

Carefully.

Use with caution:
during pregnancy (especially the first trimester) and lactation;
cardiogenic shock (systolic blood pressure less than 90 mm Hg), hypophosphatemia, severe liver failure, metabolic acidosis, risk of edema, chronic renal failure (if regular monitoring of Mg2+ concentration in the blood serum is impossible - risk of cumulation).

Use during pregnancy and breastfeeding.

Method of administration and dose.

Administered intravenously by drip or using an "Infuzomat" dosing device or intravenously by stream (slowly).
10-20 ml is prescribed intravenously once or twice a day for 5 days. Before use, the contents of 1-2 ampoules of 10 ml or 2-4 ampoules of 5 ml are diluted in 100-200 ml of 5% dextrose (glucose) solution or sterile 0.9% sodium chloride solution and administered dropwise at a rate of 20-25 drops per minute, or dilute the contents of 1 ampoule of 10 ml or 2 ampoules of 5 ml in 20 ml of a 5% dextrose (glucose) solution or sterile 0.9% sodium chloride solution and injected into a vein in a stream at a rate of no more than 5 ml per minute.

Side effect.

Nausea, vomiting, diarrhea, dry mouth, discomfort or burning in the epigastric region (in patients with anacid gastritis or cholecystitis), abdominal pain, ulceration of the mucous membrane gastrointestinal tract, bleeding from the gastrointestinal tract, flatulence, dry mouth; bradycardia, atrioventricular block, decreased blood pressure, paradoxical reaction (increased number of extrasystoles), dyspnea, itchy skin, hyperkalemia (nausea, vomiting, diarrhea, paresthesia), hypermagnesemia (facial redness, thirst, decreased blood pressure, hyporeflexia, respiratory depression, convulsions).
When administered by injection, nausea and dizziness are occasionally possible, which usually disappear when the dose of the drug is reduced. Possible development of phlebitis and thrombosis. With rapid intravenous administration - hyperkalemia, hypermagnesemia.
If any of the side effects indicated in the instructions get worse, or you notice any other side effects not specified in the instructions, tell your doctor about it.

Overdose.

Interaction with other drugs.

When used simultaneously with potassium-sparing diuretics, ACE inhibitors, beta-blockers, cyclosporine, heparin, non-steroidal anti-inflammatory drugs, the risk of hyperkalemia increases (monitoring of serum potassium levels is necessary).
Asparkam-Farmak reduces sensitivity to cardiac glycosides.
Strengthens negative dromo- and bathmotropic action antiarrhythmic drugs.
Eliminates hypokalemia caused by glucocorticosteroids and diuretics.
General anesthetics increase the depressant effect on the central nervous system; when used simultaneously with atracuronium, decamethonium, succinyl chloride and suxamethonium, neuromuscular blockade may be enhanced.

Special instructions.

Release form:

Storage conditions.

In a place protected from light at a temperature of 15 ° C to 25 ° C. Keep out of the reach of children.

Best before date.

2 years.
Do not use after the expiration date stated on the packaging.

Vacation conditions:

Legal entity in whose name the registration certificate was issued

Magnesium and potassium form the basis of Asparkam. These elements are almost completely absorbed by the body. The medicine is needed to restore metabolism, balance electrolytes in the body, and improve impulse conductivity. Helps cardiac and neurological patients. Instructions for use, as well as Full description medications are discussed in detail in our article.

Composition and dosage form

Release form: the drug is produced in tablets and ampoules. The color of the tablets is white, the surface is smooth. They have a specific smell, are flat, cylindrical in shape, and the line divides the tablet into 2 parts. Each blister contains 50 tablets, one blister constitutes a package. Composition of Asparkam:

• The tablet contains 0.175 g of each active ingredient.
• Corn starch.
• Calcium salt of stearic acid (stearate).
• Polysorbate-80.

The injection solution has a white or slightly yellowish color. Ampoules contain 5 or 10 ml. The injection form consists of dehydrated magnesium and potassium aspartate with a density of 40, 45.2 mg/ml, sorbitol (E420), water for injection. International name: Potassium aspartate & magnesium aspartate. INN: potassium and magnesium aspartate. Pharmacological group drug:

• antiarrhythmic drug;
• micro-, macroelements.

Therapeutic effect

Potassium and magnesium ions provide the therapeutic effect of Asparkam. The disturbed balance or lack of magnesium with potassium will be eliminated; many biochemical reactions occur together with these ions, so metabolic processes are normalized. In internal organs and tissue structures, potassium is considered the main positive ion of intracellular structures. It activates the production of adenosine triphosphoric acid, peptides, acetylcholine with glycogen.

ATP (adenosine triphosphoric acid) is a universal energetic molecular compound; any reaction and cellular function is carried out with the help of this molecule, including nutrition and reproduction. With the help of potassium, the cell will receive a large amount of energy (ATP is synthesized), the cell will perform various functions (contraction of myofibers, synthesis of hydrochloric acid and other reactions).

Thanks to the potassium found in Asparkam, molecules will be formed to nourish the cell, protein components will begin to renew

Potassium will speed up the work of cellular structures, increase its efficiency, and the cell will have a quick response to impulses from neurons. Due to the fact that glycogen production in the cell is stimulated, a supply of nutritional components will appear, which, if necessary, will be converted into ATP. Protein production will allow the cell to promptly replace “outdated” molecules that do not function fully with updated ones that work easily and quickly.

Acetylcholine synthesis will accelerate impulse conduction through neurons, since this component activates nerve tissue. More than 300 enzyme compounds work thanks to magnesium; these enzymes are involved in metabolism and perform specific functions for each cellular structure. The magnesium element is involved in various reactions for the production of ATP, magnesium also normalizes potassium balance, enhances the effect of potassium, the cell will work efficiently and quickly.

With the help of potassium and magnesium ions, membrane polarization of cellular structures is maintained; this is necessary in order to distinguish the external environment from the internal cytoplasm of the cell. Therefore, dangerous, unnecessary compounds will not reach the cell, and metabolites will be removed from it. The medication transports potassium and magnesium ions through the membrane membrane to the cell, where they are released from the aspartate bond, and aspartate is introduced into metabolic processes.

It will improve the production of replaceable amino acid compounds, fats, and nucleotide structures for DNA. Aspartate also optimizes energy metabolism in heart tissues experiencing hypoxia during various pathological processes. Why does Asparkam need it? These effects are carried out by Asparkam in all organs and tissue structures; the drug has a particularly beneficial effect on the heart, so it should be used for:

• Prevention of potassium deficiency in the bloodstream.
• Improves metabolism in heart tissue.
• Elimination of arrhythmia caused by a heart attack due to heart failure.
• Improved tolerability of any cardiac glycoside.
• Increasing cardiac endurance, easy tolerance of strong emotions. The person will become physically resilient.
• Improved elasticity of vascular tissues, as the product thins the blood.
• Improved impulse conduction of neurons.

If you take such a remedy, the likelihood of the formation of cerebrovascular pathological processes with a fatal outcome will decrease.

The medicine is absorbed quickly and completely. Metabolic products will be eliminated due to renal function. The serum concentration of magnesium with potassium will be maximum 1-2 hours after you take the tablet. From the blood, the drug will reach the myofibers of the heart in the form of magnesium, potassium ions with aspartate, where they will also be included in metabolic processes.

Indications

Indications for the use of Asparkam are due to its therapeutic effects. Why do they take the pill or do it? intravenous injection? The product is used:

• with heart failure;
• coronary heart disease;
• period after a heart attack;
• disturbed heart rhythm (extrasystole of the atria, ventricles, atrial, atrioventricular paroxysmal tachycardia);
• overdose, poisoning with cardiac glycosides or poor tolerance of these drugs.

If there is a lack of magnesium, potassium in the blood, caused, for example, by prolonged vomiting, diarrhea, taking drugs that do not conserve potassium, glucocorticoids, laxatives, Asparkam is used until the normal concentration of these elements is normalized

We use it correctly

The tablet is swallowed completely; there is no need to chew, break or crush it. It is better to drink with a small amount of plain water (half a glass). For therapeutic measures, you need to take two tablets 3 times a day after meals, you do not need to take them before meals. The duration of treatment will be 3 or 4 weeks. If necessary, you can repeat the course after 30 days or a quarter.

For prevention, with a lack of magnesium and potassium, use 1 tablet three times a day after the patient has eaten. The duration of treatment for prophylaxis is determined individually. If you take the drug for more than 4 weeks, it is recommended to perform a blood test every week or 14 days for potassium and magnesium concentrations. It is prohibited to take the drug more than 6 tablets per day, since magnesium and potassium will not be absorbed, and a person’s kidneys will begin to work harder.

The method of administering the injection solution is jet (the drug is slowly injected intravenously using a syringe) or intravenous infusion(dropper). Clear injection solutions are used; cloudy injections are not used. When the ampoule is opened, it must be used immediately. If injections are prescribed in combination, and they have lost transparency, then they should not be used either.

The annotation states that for treatment, 10 or 20 ml are administered every day, 1 or 2 times a day for no more than 5 days. Before administering the product, add half the volume of saline solution or a 5% glucose solution is suitable. The injection rate is 5 ml per minute. When administering drugs by drip for treatment, 300 ml of infusion solution is used 1 or 2 times a day for no more than 5 days, no more. The rate of administration will be 20–22 drops in 60 seconds. You can read more about Asparkam analogues.

special instructions

Use the product carefully, under medical supervision:

• with atrioventricular block;
• severe liver failure;
• metabolic acidosis blood;
• high probability of edema formation;
• renal dysfunction;
• low blood phosphate level.

If you are treated with Asparkam for a long time, then blood and urine are examined

Monitor blood potassium concentration during joint use potassium-sparing diuretics, β-blockers. To avoid high concentrations of potassium and magnesium in the blood, the drug is administered slowly. The drug is often used to treat strokes and heart attacks. When treating with Asparkam, an ECG is systematically performed. In the acute stage pathological process Intravenous administration of the drug is indicated.

Overdose

If the patient does not drink the medicine correctly, then such treatment will not be beneficial, but harmful, an overdose will occur, side effects:

• The heart rate will slow down and it may become paralyzed and stop.
• Blood pressure will decrease.
• The patient will feel sick and vomit.
• Respiratory center will be paralyzed.
• The bladder will loosen.

If such signs appear, the patient is indicated for intravenous administration of calcium chloride.

Asparkam and other means

When treated with Asparkam, intestinal motility is inhibited, constipation will appear, and the likelihood of a hyperkalemic state will increase if used with potassium-sparing diuretics, angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, Heparin, Cyclosporine.

Tetracycline and products containing iron and sodium fluoride will also be absorbed slowly. For normal absorption, these drugs are taken 3 hours after taking Asparkam. The effect of muscle relaxants with antidepolarizing effects increases, the effect of some antibacterial agents(with treatment with Neomycin, Tetracycline, Streptomycin, Polymyxin B).

Side effects

If the patient does not comply with the doctor’s prescription or takes the medicine incorrectly, then side effects will appear. The patient will feel nauseous and vomit, feel dizzy, have a swollen stomach, diarrhea, discomfort in the epigastric zone with pain and burning. Constipation, ulcers of the gastric and intestinal mucosa, and hemorrhages may occur. Heart blockade will occur; with frequent injections, the venous walls will become irritated; venous thrombosis with phlebitis. The heart rate will slow down, blood pressure will decrease, the face will turn red, and the skin will itch. A hyperkalemic, hypermagnesemic state will appear.

If the dose of Asparkam is not observed, the oral cavity will become dry and the person will feel tired

When not to take

If there are contraindications, then it is necessary to be treated with analogues. Do not use Asparkam:

• with acute or chronic renal failure;
• low blood pressure;
• increased magnesium and potassium concentrations in the blood;
• oliguria, anuria;
• atrioventricular block stage 2 or 3;
• erythrocyte hemolysis;
• adrenal dysfunction, chronic insufficiency of the adrenal cortex;
• in a state of shock;
• acute blood acidosis;
• dehydration of the body;
• difficult flowing;
• poisoning with methanol compounds;
• impaired amino acid metabolism.

Storage conditions and terms

Store the tablet form of the drug and the solution at a temperature not higher than 25 ºС, not lower than 15 ºС for the solution. Tablets should be protected from high humidity, and ampoules from solar radiation. The shelf life of the tablets is 3 years, and the solution is 2 years after manufacture. No prescription is needed for the tablets.

Diuretics with Asparkam

The combination of Diacarb or Furosemide with Asparkm is necessary to eliminate high blood pressure and edematous changes, including edema of cerebral structures. If it is necessary to use diuretics, then use the following combination of drugs (Diacarb or Furosemide with Asparkam). Diuretics will remove fluid, so the amount of circulating blood and blood pressure in the body will decrease, and water from the tissue will begin to flow into the bloodstream, swelling will disappear. Asparkam will replenish the potassium removed by diuretics, therefore their side effects are neutralized, they can be used for a long period to achieve a therapeutic effect.

Asparkam and sports

To support the heart of a person involved in bodybuilding and other types of strength sports during prolonged intense physical activity, arrhythmic condition, NCD, maladaptation, the drug is indicated. Athletes often have a hypokalemic condition, manifested by cramps, muscle weakness, and arrhythmia. Potassium is lost in an athlete due to the fact that he eats food rich in protein components. If they break down, toxic compounds are formed that “load” the liver and kidneys.

To release toxins, you need to drink a lot of fluid, and potassium ions will be excreted in your urine. Magnesium and potassium ions are also lost through sweat. These ions will relax muscles, eliminate cramps, improve heart function, and make it more resilient. The likelihood of sudden fatal outcome during intense sports activities. Asparkam is combined with Riboxin, which will increase the amount of blood ejected with the force of heart contractions. That's why internal organs, tissue structures will be better supplied with blood.

Asparkam compensates for the body's needs for potassium and magnesium ions in athletes involved in heavy sports

Riboxin will also restore myofibers faster after training, normalize heart rate, and exhibit an anabolic effect, thanks to which you will gain weight faster. muscle mass. For athletes, Asparkam is taken no more than 1 tablet 3 times a day for 30 days. Riboxin is taken 2 tablets 3 times a day for 30 days.

Each drug can be taken together or separately every quarter. You can find out about the possibility of prescribing Asparkam to children. It is important to remember that the course of treatment is prescribed only by the attending physician; self-medication will cause complicated conditions that are not always treated successfully, so it is better not to risk your health.

Asparkam is medicinal product– a source of magnesium and potassium ions, which regulate metabolic processes in the body. The product also contains aspartate - transfer of ions through cell membranes. The drug is prescribed for diseases associated with heart rhythm disturbances, angina pectoris and for the prevention of stroke.

Asparkam is available in tablets and as an injection solution.

pharmachologic effect

According to the instructions, Asparkam is a source of such important substances as potassium and magnesium. It helps normalize electrolyte balance. Magnesium is a cofactor in many enzyme reactions (about 300) and promotes the penetration of potassium into cells. Potassium has an antiarrhythmic effect and also supports normal heart function.

After using Asparkam, its components are quickly absorbed into the gastrointestinal tract. The drug is eliminated mostly through the kidneys. 1-2 hours after taking Asparkam tablets or administering injections, the concentration active substances(magnesium and potassium) in the blood reaches its maximum level. From the blood plasma, the drug penetrates into cardiomyocytes in the form of Mg2+ and K+ ions, as well as aspartate, immediately entering into cellular metabolism.

Indications for use of Asparkam

According to the instructions, Asparkam is indicated:

• To improve the effectiveness and tolerability of cardiac glycosides;
• As part complex therapy heart failure, heart rhythm disturbances, conditions after suffered a heart attack myocardium;
• For conditions accompanied by hypomagnesemia and hypokalemia.

Contraindications for use

The use of Asparkam is contraindicated for the following diseases and physiological characteristics patients:

• Acute and chronic renal failure;
• Hypersensitivity or intolerance to drug components;
• Addison's disease;
• Cardiogenic shock (blood pressure<90 мм. рт. ст.);
• Hypermagnesemia and hyperkalemia;
• Atrioventricular block 2-3 degrees.

Methods of using Asparkam

Asparkam tablets are taken orally. The dosage is 1-2 pcs. three times a day. It is recommended to take Asparkam tablets immediately after meals.

When using the solution, the dose is 10-20 ml, it is administered intravenously 1-2 times a day. In this case, the course of treatment lasts 5 days. However, the exact dosage and duration of treatment is prescribed by the doctor depending on the type and course of the disease, as well as the general condition of the patient and his medical history.

Side effects of Asparkam

The instructions for Asparkam indicate that side effects develop extremely rarely. However, taking the drug can lead to malfunctions of the digestive system, namely nausea, vomiting, abdominal pain, diarrhea, gastrointestinal bleeding, discomfort in the epigastric region, dry mouth, ulcers of the mucous surface of the gastrointestinal tract.

Also, according to reviews of Asparkam, disorders of the cardiovascular system are possible: decreased blood pressure, impaired myocardial conduction, AV block.

Allergic reactions in response to taking the drug can manifest as redness of the skin, itching and rash.

According to reviews of Asparkam, some patients complain of convulsions, paresthesia and hyperreflexia, which is a disruption of the central nervous system and peripheral nervous system.

Rarely, respiratory depression may occur due to hypermagnesemia. In addition, some reviews of Asparkam talk about such a side effect as a feeling of heat.

As for drug overdose, to date no such cases have been recorded. However, according to the instructions, Asparkam in large quantities can theoretically lead to the following symptoms: nausea, vomiting, metallic taste in the mouth, abdominal pain, weakness, bradycardia, muscle paralysis, disorientation, paresthesia of the limbs, thirst, redness of the facial skin, arterial hypotension, convulsions, impaired neuromuscular transmission, arrhythmia. In this case, it is necessary to stop taking Asparkam and undergo symptomatic therapy, including intravenous administration of a calcium chloride solution at a dosage of 100 mg/min. If the need arises, the patient undergoes hemodialysis.

Storage conditions

Additional Information

Diacarb is a medicine that is often prescribed in cases of increased intraocular or intracranial pressure. Often in the recipe there is a combination of “Diacarb and Asparkam” - doctors prescribe them together. The fact is that the second drug helps prevent the side effects of the first.

When treated with Diacarb, the body loses a large amount of sodium ions and, accordingly, potassium, which can lead to negative consequences.

Potassium is a vital element involved in cellular metabolism. The myocardium – the heart muscle – especially needs it. The body also needs magnesium, which takes part in carbohydrate metabolism and transports energy to each cell to carry out biochemical reactions.

Normal heart rhythm is characteristic of the myocardium when it responds to an increase in magnesium concentration by decreasing excitability and conductivity. But with a large amount of potassium, the contractility of the heart muscle is inhibited, which can lead to cardiac arrest. This effect is possible with an overdose of Asparkam administered intravenously.

Potassium deficiency is accompanied by lethargy, muscle weakness, heart rhythm disturbances, and decreased performance.

Asparkam restores the content of potassium and magnesium and promotes the rapid penetration of these substances into cells. Thanks to taking Asparkam with Diacarb, the osmotic pressure in the cells is restored, providing them with sufficient energy. Also, the combination with Asparkam increases blood acidity and removes bicarbonates from the body.

The simultaneous use of Diacarb and Asparkam allows you to compensate for the side effects of the former in the form of loss of potassium ions and an increase in blood alkalinity.

Neurologists often prescribe these drugs to patients to reduce intracranial pressure in various diseases and the consequences of traumatic brain injuries.

Recipe (international)

Rp.: Tab. "Asparcamum" No. 10

D.S. 1 tablet 3 times a day after meals

Rp.: Sol. "Asparcamum" 10 ml

D. No. 10 in amp.

Recipe (Russia)

Rp.: Tab. Potassii aspartati 175 mg

Magnesii aspartati 175 mg

S. 1 tablet 3 times a day after meals

Rp.: Sol. Potassii aspartati 45.2 mg

Magnesii aspartati 40 mg

D. No. 10 in amp.

S.: Administer 10-20 ml intravenously slowly. Dilute the contents of the ampoule in 50-100 ml of 5% glucose solution.

Active substance

Potassium and magnesium aspartate (Potassium aspartate and magnesium aspartate)

pharmachologic effect

A source of potassium (K+) and magnesium (Mg2+), regulates metabolic processes, helps restore electrolyte balance, and has an antiarrhythmic effect.
K+ is involved both in the conduction of impulses along nerve fibers and in synaptic transmission, muscle contractions, and maintaining normal cardiac activity. Violation of K+ metabolism leads to changes in the excitability of nerves and muscles. Active ion transport maintains a high K+ gradient across the plasma membrane.
In small doses, K+ dilates the coronary arteries, in large doses it narrows. It has a negative chrono- and bathmotropic effect, in high doses - a negative ino- and dromotropic effect, as well as a moderate diuretic effect.
Mg2+ is a cofactor in 300 enzyme reactions. An irreplaceable element in processes that ensure the supply and consumption of energy.
Participates in the balance of electrolytes, ion transport, membrane permeability, neuromuscular excitability. It is part of the structure of (pentose phosphate) DNA, participates in RNA synthesis, the apparatus of heredity, cell growth, and in the process of cell division. Limits and prevents excessive release of catecholamine under stress, lipolysis and release of free fatty acids are possible.
It is a “physiological” BMCC. Promotes the penetration of K+ into cells. Aspartate promotes the penetration of K+ and Mg2+ into the intracellular space and stimulates the intercellular synthesis of phosphates.

Mode of application

For adults: Asparkam is administered intravenously by drip or using an "Infusomat" type dosing device, or intravenously by stream (slowly).

For intravenous infusion, the contents of 1-2 ampoules of 10 ml or 2-4 ampoules of 5 ml are diluted in 100-200 ml of a sterile 0.9% sodium chloride solution or 5% glucose solution.
Adults are administered intravenously at a rate of 25 drops per minute, 10-20 ml, 1-2 times a day.
For intravenous injection, the contents of 1 ampoule of 10 ml or 2 ampoules of 5 ml are diluted in 20 ml of a sterile 0.9% sodium chloride solution or 5% glucose solution and administered no faster than 5 ml per minute. The duration of treatment with Asparkam is determined by the doctor and is, on average, 8-10 days.

Pills.
Prescribed orally for adults, 1-2 tablets 3 times a day after meals.
The course of treatment is 3-4 weeks.
For children:

Asparkam is given to children in the form of tablets:

Less than a year: 1/4 tablet 1 time per day.

From 1 to 3 years: 1/2 tablet once a day.

From 4 to 6 years: 1/2 tablet 2 times a day.

From 7 to 10 years: 1/2 tablet 3 times a day.

From 11 to 12 years: 1 tablet 1-2 times a day.

From 13 to 16 years: 1 tablet 2 times a day.

From 16 years: 1 tablet 3 times a day.

Indications

Pills.
As part of complex therapy
- heart failure, conditions after myocardial infarction, heart rhythm disturbances (mainly ventricular arrhythmias) caused by electrolyte disturbances;
- to enhance the effectiveness and improve the tolerability of cardiac glycosides;
- in conditions accompanied by hypokalemia and hypomagnesemia (including overdose of saluretics).

Solution for injections.
As part of complex therapy for heart failure, myocardial infarction, cardiac arrhythmias (mainly ventricular arrhythmias); to improve the tolerability of cardiac glycosides.

Contraindications

Renal failure in acute and chronic form;
hyperkalemia (excess potassium in the body);
hypermagnesemia (excess magnesium in the body); severe form of myasthenia.

Asparkam is contraindicated in the first trimester of pregnancy. In the second and third trimester, the drug is used only as prescribed by a doctor. During pregnancy, Asparkam is usually used in tablet form.

Side effects

Nausea, vomiting, diarrhea, abdominal pain, ulceration of the gastrointestinal mucosa, bleeding from the gastrointestinal tract, flatulence, dry mouth; AV blockade, paradoxical reaction (increased number of extrasystoles), bradycardia, decreased blood pressure; phlebitis, venous thrombosis, dyspnea, skin itching, hyporeflexia, dizziness, paresthesia; myasthenia gravis, asthenia, increased sweating. With rapid intravenous administration - hyperkalemia, hypermagnesemia.

Overdose. Symptoms: hyperkalemia (muscle hypotonicity, paresthesia of the extremities, slowing of AV conduction, arrhythmias, cardiac arrest). Early clinical signs of hyperkalemia usually appear when the K+ concentration in the blood serum is more than 6 mEq/L: sharpening of the T wave, disappearance of the U wave, decreased S-T segment, prolongation of the Q-T interval, widening of the QRS complex.

More severe symptoms of hyperkalemia - muscle paralysis and cardiac arrest - develop at a K+ concentration of 9-10 mEq/L. Treatment: orally or intravenously - NaCl solution; IV - 300-500 ml of 5% dextrose solution (with 10-20 IU of insulin per 1 l); if necessary, hemodialysis and peritoneal dialysis.

Release form

Tablets 1 tablet. = magnesium aspartate 175 mg, potassium aspartate 175 mg

in a blister pack 50 pcs.; in a cardboard pack 1 package.

injection solution ampoule 5 ml, No. 10

injection solution ampoule 10 ml, No. 10

Potassium aspartate 45.2 mg/ml, magnesium aspartate 40 mg/ml

ATTENTION!

The information on the page you are viewing is created for informational purposes only and does not in any way promote self-medication. The resource is intended to provide healthcare workers with additional information about certain medications, thereby increasing their level of professionalism. The use of the drug "" necessarily requires consultation with a specialist, as well as his recommendations on the method of use and dosage of the medicine you have chosen.