Sorbifer during pregnancy: what is this drug prescribed for? Sorbifer Durules ® Sorbifer method of application
Instructions for medical use
medicine
Sorbifer ® Durules ®
Tradename
Sorbifer ® Durules ®
International nonproprietary name
Dosage form
Film-coated tablets
Compound
One tablet contains
active substances: iron (II) sulfate dry 320 mg (equivalent to 100 mg iron (II)), ascorbic acid 60 mg,
Excipients: povidone (K-25), polyethene powder, carbomer 934 R, magnesium stearate,
shell composition: hypromellose, macrogol 6000, titanium dioxide E 171, iron (III) yellow oxide E 172, solid paraffin.
Description
Tablets are lenticular-shaped, slightly biconvex, ocher-coated - yellow color, with “Z” engraving on one side, with a characteristic smell.
Pharmacotherapeutic group
Hematopoiesis stimulants. Iron supplement. Fe++ preparations for oral administration.
ATX code B03A A
Pharmacological properties
Pharmacokinetics
"Durules" is a special production technology that ensures gradual release active substance(iron ions), uniform supply medicinal product. Iron is absorbed primarily in the duodenum and proximal jejunum. Taking 100 mg twice a day provides 30% greater absorption of iron from Sorbifer Durules compared to conventional iron supplements. Absorption and bioavailability of iron are high. Connection with plasma proteins - 90% or more. Deposited in the form of ferritin and hemosiderin in hepatocytes and cells of the phagocytic macrophage system, a small amount - in the form of myoglobin in muscles. The half-life is 6 hours.
The presence of ascorbic acid in the preparation creates more favorable conditions for the absorption of iron in the intestines. At the molecular level ascorbic acid mobilizes iron from the crystalline core of ferritin in vitro, reducing Fe 3+ to Fe 2+ . At the intracellular level, ascorbic acid enhances iron-induced ferritin translation by promoting the conversion of iron regulatory protein (IRP) from its RNA-bound form to aconitase.
Pharmacodynamics
Iron is an essential component of the body, necessary for the formation of hemoglobin and the implementation of oxidative processes in living tissues. The active substance is contained in a biologically indifferent plastic matrix with a spongy structure. When passing through the gastrointestinal tract from the porous matrix of the tablets (within 6 hours), a continuous release of ferrous ions occurs. The film coating of the tablet and the porous matrix provide long-term release of iron ions. The film coating of the tablet, which completely disintegrates under the action of intestinal peristalsis and releases the active ingredient, helps prevent the tablet from dissolving in the stomach. The slow release of iron ions does not create a high local concentration, which avoids irritation of the mucous membrane gastrointestinal tract.
Ascorbic acid slows down the breakdown of ferritin by blocking autophagy of ferritin by ferritin lysosomes and transformation into hemosiderin.
Ascorbic acid accelerates the absorption of iron in the gastrointestinal tract, reducing unbound heme iron (III) to iron (II) in the stomach.
Indications for use
Iron-deficiency anemia
Latent iron deficiency in the body (without anemia), associated with excessive iron losses (bleeding, including uterine bleeding, constant donation), poor nutrition
Conditions accompanied by an increased need for iron in the body (prevention during pregnancy, lactation and in blood donors)
Directions for use and doses
The tablet should be taken whole, without chewing, and at least half an hour before meals, with half a glass of water.
Adults and teenagers over 12 years old:
For patients with grade II-III iron deficiency anemia, if necessary, on the recommendation of a doctor, the dose can be increased to 3-4 tablets 2 times a day (morning and evening) with a duration of use of 3-6 months.
During pregnancy:
The drug is used in cases of established iron deficiency (iron deficiency anemia and latent iron deficiency in the body)
Prophylactic dose: 1 tablet per day.
Therapeutic dose: 1 tablet 2 times a day (morning and evening).
Treatment should be carried out until hemoglobin levels normalize and continue until the iron depot is completely saturated for another 2 months. Individual long-term therapy (with or without interruptions) is indicated for regularly occurring significant iron loss (for example, with heavy menstruation).
Side effects
Frequency of side effects digestive system increases with increasing dose from 100 to 400 mg per day.
Often (>1/100)
Nausea, abdominal pain, diarrhea, constipation
Rarely (<1/100)
- ulcerative lesions of the esophagus, stenosis of the esophagus
Allergic reactions (itching, rash, hyperemia)
Hyperthermia
Contraindications
Hypersensitivity to the active or any other inactive component of the drug
Esophageal stenosis and/or other obstructive changes in the digestive tract
Increased iron content in the body (hemosiderosis, hemochromatosis)
Repeated blood transfusions
Impaired iron utilization (lead anemia, sideroblastic anemia, hemolytic anemia)
Children under 12 years of age (due to lack of clinical data)
Drug interactions
- ciprofloxacin: Concomitant use reduces the absorption of ciprofloxacin by approximately 50%, so there is a risk that the content of ciprofloxacin in the blood plasma will be lower than necessary for a therapeutic effect.
- levofloxacin: simultaneous use reduces the absorption of levofloxacin.
-moxifloxacin: Concomitant use reduces the bioavailability of moxifloxacin by almost 40%, therefore, if simultaneous use is required, it is necessary to ensure the longest possible period between taking moxifloxacin and Sorbifer Durules.
- norfloxacin: Concomitant use reduces the absorption of norfloxacin by approximately 75%.
- ofloxacin: Concomitant use reduces the absorption of ofloxacin by approximately 30%.
When using Sorbifer Durules concomitantly with the following drugs, dosage adjustment of these drugs may be required. The recommended minimum time interval between taking Sorbifer Durules and these drugs should be at least 2 hours:
- calcium or dietary supplements containing magnesium carbonate, as well as aluminum or calcium hydroxide, antacids containing magnesium carbonate, together with iron salts they form a complex that reduces the absorption of each other.
- captopril: Concomitant use reduces the area under the plasma concentration-time curve for captopril by approximately 37%, presumably due to chemical reactions in the gastrointestinal tract.
- zinc: simultaneous use reduces the absorption of zinc salts.
- clodronate: Concomitant use may reduce the absorption of clodronate.
- deferoxamine: with simultaneous use, the absorption of deferoxamine and iron is reduced due to the formation of a compound.
- levodopa: When used concomitantly, ferrous sulfate reduces the bioavailability of single doses of levodopa by approximately 50% and of single doses of carbidopa by 75%, possibly due to the formation of a chelate.
- methyldopa: When used concomitantly, the bioavailability of methyldopa is reduced, possibly due to the formation of a chelate.
- penicillamine: Concomitant use of penicillamine and iron salts reduces their absorption, possibly due to the formation of a chelate.
- risedronate: carried out in vitro Studies have shown that preparations containing iron form compounds with risedronate. Although no drug interaction studies have been conducted in vivo, it can be assumed that the simultaneous use of these drugs reduces the absorption of risedronate.
- tetracyclines: with simultaneous use, the absorption of tetracyclines and iron is reduced. If simultaneous use is necessary, the recommended minimum time interval between taking Sorbifer Durules and these drugs should be at least 3 hours. When taken orally, iron inhibits the enterohepatic circulation of oxytetracyxine (doxycycline), as well as when administered intravenously.
- hormones thyroid gland : with the simultaneous use of iron and thyroxine preparations, a decrease in the absorption of thyroxine is possible, which reduces the effectiveness of replacement therapy.
-cimetidine: with simultaneous use, a decrease in gastric acid production caused by cimetidine reduces iron absorption. Therefore, the intervals between taking these drugs should be at least 2 hours.
-chloramphenicol: When taken simultaneously, the clinical effect of iron treatment may be delayed.
When taking the drug simultaneously with tea, coffee, eggs, dairy products, wheat bread, porridge or foods rich in plant fiber, iron absorption may be reduced.
Iron supplements can cause poisoning in children. When using the drug, darkening of the stool appears, which has no clinical significance.
The drug is used with caution for gastric and duodenal ulcers, inflammatory bowel diseases (enteritis, diverticulitis, ulcerative colitis, Crohn's disease), chronic liver and kidney diseases.
Comprehensive laboratory and instrumental monitoring of the effectiveness of treatment is recommended to be carried out every 7-14 days, depending on the course of anemia.
Pregnancy and lactation
The drug can be used during pregnancy and lactation.
Features of the effect of the drug on the ability operate a vehicle or potentially dangerous machinery.
Does not affect.
Overdose
Symptoms: abdominal pain, vomiting and diarrhea (sometimes with blood), fatigue, weakness, hyperthermia, paresthesia, pale skin, cold clammy sweat, acidosis, weak pulse, decreased blood pressure, palpitations. Signs of peripheral circulatory collapse, coagulopathy, hyperthermia, hypoglycemia, liver damage, renal failure, muscle cramps and coma may appear after 6-12 hours.
Treatment: gastric lavage, milk and raw eggs orally, drugs that provoke vomiting, symptomatic therapy.
If necessary, perform a gastric lavage with a solution of deferoxamine at a concentration of 2 g/l, then 5 g of deferoxamine is dissolved in 50-100 ml of water and this solution is left in the stomach.
In case of severe intoxication: in a state of shock and/or coma and in case of increased serum iron levels (> 90 mmol/l in children, > 142 mmol/l in adults), intensive care should be started immediately and deferoxamine should be administered (15 mg/l). kg/h intravenously slowly, maximum 80 mg/kg/24 hours). Too much high speed infusion may result in hypotension.
In less severe cases of intoxication, deferoxamine can be administered intramuscularly (50 mg/kg, total dose not more than 4 g).
Release form and packaging
30 and 50 tablets are placed in brown glass bottles, sealed with a polyethylene cap and equipped with an accordion shock absorber for glass bottles. The bottle, together with instructions for medical use in the state and Russian languages, is placed in a lithographed cardboard box.
Storage conditions
Store at a temperature not exceeding 25 °C.
Keep out of the reach of children!
Shelf life
Do not use after expiration date.
Conditions for dispensing from pharmacies
Over the counter
Manufacturer
JSC "EGIS PHARMACEUTICAL PLANT"
1106 BUDAPEST, st. Keresturi, 30-38 HUNGARY
Some facts about the product:
Instructions for use
Price in online pharmacy website: from 376
Description
Sorbifer Durules is a pharmaceutical product belonging to the group of drugs containing iron. The main purpose of the drug is the treatment of anemia caused by a deficiency or disorder of iron absorption in the body.
Available form, composition
Available in the form of coated tablets, convex on both sides light yellow color. One side part is marked with the letter “Z”; inside there is a grayish tablet with a specific odor.
Compound
Active ingredients: iron sulfate 320 mg (equivalent to the amount of divalent iron - 100 mg), ascorbic acid - 60 mg.
And other inactive ingredients of the constituent part.
Pharmacodynamics
Iron is the most important biologically significant ingredient involved in hematopoiesis and reactions that change the degree of oxidation of substances in the body. Sorbifer Durules is used to prevent iron deficiency. After all, this element is the structural basis of some proteins, as well as hemoglobin, which carries oxygen from the lungs to the bloodstream, to organs and tissues. The pharmaceutical method involves the release of iron ions in several stages over a long period of time. The matrix structure of Sorbifer Durules plastic is inactive in gastric juice, but dissolves under the action of contractions of the intestinal walls, which activate the active ingredient.
Ascorbic acid promotes the absorption of ferrous sulfate from space duodenum. Vitamin C is involved in the complex processes of creating blood, where red blood cells form and mature. After oral administration of the drug Sorbifer Durules, the active component almost instantly enters the general bloodstream, spreading through the tissues and becoming involved in metabolism.
Pharmacokinetics
Sorbifer Durules technology provides for a smooth release of the active ingredient and its uniform distribution.
The absorption and bioavailability of iron ions is very high. Iron is absorbed to a large extent in the duodenum or proximal mesentery small intestine. More than 90% bound to plasma proteins. It accumulates in liver parenchyma cells and mononuclear phagocyte cells; a small proportion is found in the muscular system. The process of half elimination of the substance from the body reaches 6 hours.
Indications
Instructions for use of Sorbifer Durules provide for its use in case of iron deficiency and the development of hematological syndrome, with a disorder of hemoglobin synthesis due to iron deficiency.
To prevent pathology, it is used by pregnant women and while feeding the baby with breast milk. Almost always, this period of a woman’s life is accompanied by signs of low iron content in the body.
The pharmaceutical product is indicated for blood donors.
Contraindications for use
There is a spectrum of pathologies and physiological conditions in which the use of Sorbifer Durules is unacceptable:
- Obstructions of the digestive system, in which the process of moving food is disrupted (reduction of the internal lumen of the esophagus caused by injuries, tumors and other reasons).
- Pathologies that are accompanied by an increase in the concentration of iron in the body (with excessive deposition of hemosiderin in tissues, with hereditary disorders of the metabolism of iron-containing pigments and its excessive accumulation in tissues)
- When there is a disorder in the process of iron utilization in the body in diseases leading to the destruction of red blood cells, lead, sideroblastic anemia.
- In case of individual hypersensitivity to the components of the pharmaceutical product.
- Children under 12 years of age, since clinical trials on the safety of the drug for children have not been conducted.
With special caution, the medication is prescribed in the presence of ulcerative pathologies on the walls of the stomach or duodenum, with inflammatory processes intestines (inflammation in the small intestine, pathologies of the large intestine, Crohn's disease, the presence of diverticula in the intestine). Before starting therapy with Sorbifer Durules, it is necessary to exclude these pathologies.
Pregnancy and breastfeeding
The pharmaceutical product is not contraindicated during pregnancy and breastfeeding.
Adverse reactions
During therapy, undesirable reactions may occur: stool disorders, vomiting, discomfort in the epigastric region and pharynx, pain in the epigastric zone. The occurrence of adverse reactions increases in the gastrointestinal tract due to an increase in dosage to 400 mg.
Undesirable reactions such as esophageal ulcer, reduction of the internal lumen of the esophagus, allergic manifestations (rash on skin, itching). Redness of the skin, cephalalgia, dizziness and loss of vitality are also observed.
Direction of administration, dose
The instructions for the pharmaceutical product describe the doses and order of administration of Sorbifer Durules. For adults, the therapeutic dose is 1 tablet 1-2 times a day. In severe cases of pathology, the attending doctor may increase the dose to 3-4 tablets per day, divided into 2 doses.
For preventive purposes, 1 tablet per day is prescribed for pregnant women; for therapeutic purposes, 1 tablet twice a day. On average, the duration of treatment lasts up to 2 months. Discontinue the medication after stabilization normal level hemoglobin in the blood.
Take the medicine 40 minutes before eating or 2 hours after eating. Swallow the tablets without chewing, washing them down with a sufficient amount of liquid.
Overdose
If the dose of a pharmaceutical drug required for treatment is exceeded, it is noted strong pain in the epigastric zone, blood pressure decreases significantly, a distinct heartbeat and low pulse appear, body temperature decreases, and sensitivity is impaired.
In case of severe overdose, blood clotting disorders, increased body temperature, severe disorders of liver and kidney function, convulsions and coma are noted, which develop within a period of 6-12 hours.
Overdose therapy is carried out in a hospital setting. Gastric lavage is prescribed. Raw eggs and milk are used to bind iron ions in the stomach and intestinal tract. Treatment is carried out according to symptoms.
Interaction with other medications
Iron absorption is reduced when the drug is used together with antacid medications containing magnesium carbonate and aluminum hydroxide. It is necessary to observe a time interval between the use of medications of up to 2 hours, and when using Sorbifer Durules together with tetracyclines, the interval increases to 3 hours.
The pharmaceutical product does not combine with ciprofloxacin, doxycycline, norfloxacin and ofloxacin.
special instructions
Sometimes there is a change in shade feces(darkening is not clinically significant)
Release form
Coated tablets of 30, 50 tablets in a dark glass bottle. Instructions are included in the cardboard packaging.
Dispensed by pharmacies
Sold from pharmacies using a prescription.
Storage
The pharmaceutical product is stored in a dry place at 15–25 °C, away from the reach of children.
Best before date
The shelf life is no longer than 3 years, subject to storage rules. After the expiration date, use is unacceptable
Instructions for use:
Sorbifer ( international name– Ferrous sulfate + Ascorbic acid) belongs to the group of antianemic drugs that replenish iron deficiency. The drug is highly effective and safe, due to which it is prescribed during pregnancy and breastfeeding.
Sorbifer is widely used as an effective stimulant for restoring iron levels in the body after serious illnesses, operations and prolonged bleeding.
Composition and release form
The main active ingredients are ascorbic acid 60 mg and ferrous sulfate 100 mg.
Auxiliary components: magnesium stearate, polyethylene powder, carbomer, povidone.
Sorbifer is available in tablets of 160 mg in cardboard packaging of 30-50 pcs. Each tablet is coated with a coating consisting of paraffin, iron oxide, titanium dioxide, hypromellose and macrogol.
Pharmacological properties of Sorbifer
Sorbifer is combination drug effective for restoring iron levels in various types of anemia. Thanks to the combination of ferrous sulfate and ascorbic acid, an antianemic effect is achieved.
Sorbifer has good reviews as a highly absorbable drug with a gradual release of iron ions, which avoids excess iron in the gastrointestinal tract and blood.
Ferrous sulfate and vitamin C promote hemoglobin production and oxygen transport. Ascorbic acid acts as an antioxidant and collagen, ensuring tissue regeneration.
According to the description, Sorbifer is effective in cases of impaired absorption of iron and its chronic deficiency in the body.
Indications for use of Sorbifer
Sorbifer is prescribed for iron deficiency anemia of various etiologies, including during pregnancy and lactation, in postoperative period, after suffering severe illnesses and bleeding, chronic diarrhea.
Sorbifer received positive reviews as an effective preventive medicine with diets, unbalanced nutrition and low iron absorption.
Instructions for use
In accordance with the instructions, Sorbifer should be taken orally 2-3 times a day, 2 tablets after meals, with plenty of water. Daily dose the drug is 100 - 200 mg, depending on the patient’s diagnostic indications.
For iron deficiency anemia, the drug should be taken 2 tablets 2 times a day, and to prevent iron deficiency - 100 mg once a day.
According to the instructions, Sorbifer should not be taken by children under 12 years of age.
Use during pregnancy
When a pregnant woman is diagnosed with iron deficiency, Sorbifer is prescribed. The drug can be taken both for the treatment and for the prevention of anemia during the second and third trimester of pregnancy. Sorbifer can also be prescribed for multiple pregnancies with bleeding.
Sorbifer during pregnancy should be taken after meals, 2 times a day, one tablet. The daily dose should not exceed 200 mg. The dosage is determined in accordance with the patient’s tests. At correct dosage hemoglobin increases within 2-3 weeks after starting treatment.
While taking the drug, a pregnant patient should not consume foods and medications with a high calcium content. There should be 2-3 hours between taking Sorbifer and antacid medications.
Sorbifer is contraindicated in pregnant patients with esophageal stenosis, metabolic disorders, severe gastrointestinal diseases and excess iron levels.
Contraindications
Contraindications to the use of Sorbifer are hypersensitivity and intolerance to the components of the drug, increased iron content, bleeding and severe diseases of the gastrointestinal tract, renal and liver failure, peptic ulcer.
The drug is prescribed with caution to patients after blood transfusion, with colitis and Crohn's disease.
Side effects of Sorbifer and reviews
According to the description and reviews, Sorbifer does not cause serious side effects.
In rare cases, when taking the drug, you may experience allergic reactions and disorders of the gastrointestinal tract - nausea, vomiting, constipation, urticaria, dermatitis, bronchospasm, diarrhea.
Sorbifer is a modern antianemic drug that is used for iron deficiency conditions of varying severity. The medicine is sold in pharmacies with a prescription.
Composition and release form
Sorbifer is available in the form of yellow tablets that have a hard shell. The shape of the tablets is convex on both sides. On one side there is an engraving in the form of the letter Z. In cross-section, the tablet has grey colour and a pronounced odor.
The drug is packaged in bottles or cardboard packs of 30 or 50 tablets in each package.
Composition of Sorbifer:
- Ferrous sulfate (320 mg).
- Ascorbic acid (60 mg).
There are also additional components: magnesium stearate, polyethylene powder, povidone K-25, carbomer 934R.
The tablet shell has its own composition: yellow iron oxide, hypromellose, solid paraffin, macrogol 6000, solid paraffin, titanium dioxide.
Indications for use
Sorbifer is prescribed for iron deficiency and associated anemia. It is also used for prevention during pregnancy, breastfeeding or blood donation.
Instructions for use and dosage of Sorbifer
Take the tablets orally without chewing. You can drink plenty of water (at least half a glass). The dosage for adults is 1 tablet once or twice a day. If iron deficiency anemia develops rapidly and is in the acute phase, the dose of Sorbifer can be increased to 3-4 tablets. You should drink them in the morning and evening (2 doses in total). The course of treatment is several months (on average, 3-4 months) until sufficient accumulation of iron in the body.
During pregnancy and lactation, Sorbifer is taken to prevent iron deficiency. The preventive dosage is one tablet per day. If it is necessary to treat this group of patients with the drug, the dose is 2 tablets per day.
During therapy, hemoglobin levels should be constantly monitored, and if satisfactory levels are achieved, the dosage of the drug may be reduced or discontinued.
The average duration of treatment and prevention with Sorbifer for pregnant and lactating women is 2 months.
Contraindications
According to the instructions for use, Sorbifer should not be taken if you have the following diseases:
- Hemosiderosis, hemozromatosis and other conditions indicating increased iron content in the body.
- Obstruction or stenosis of the esophagus, other gastrointestinal pathologies.
- Dysfunction of iron utilization (with lead, hemolytic or sideroblastic anemia).
- Sensitivity to the components of the drug.
Special instructions for use and warnings
Take Sorbifer with extreme caution for enteritis, ulcerative colitis, Crohn's disease and other diseases of the duodenum and intestinal inflammation.
With prolonged therapy with the drug, darkening of the stool is possible. This is not a clinical disorder and therefore does not require corrective action.
How does Sorbifer work?
The drug was created using innovative technology Durules, which allows for the gradual release of iron, as the main active component of the medicine.
Using a plastic matrix in tablets, which is completely inert in the stomach and quickly disintegrates in the intestines, active substance is released gradually and completely, and ascorbic acid promotes better absorption of iron.
Side effects of Sorbifer
The most pronounced side effects can be observed from the gastrointestinal tract and esophagus: nausea, constipation, or vice versa - diarrhea, abdominal pain, ulcer or stenosis of the esophagus. Intensity side effect increases with increasing daily dosage drug.
Local allergic reactions – itching, rash – can rarely be noticed.
From the outside nervous system sometimes there is pain in the head. May also be noted general weakness and skin hyperthermia.
Interaction of Sorbifer with other drugs
The drug reduces the rate of absorption of enoxacin, levodopa, methyldopa, grepafloxacin, penicillamine, levofloxacin, clodronate, and thyroid hormones when taken simultaneously.
Also, it should not be combined with antacid medications that contain magnesium carbonate or aluminum hydroxide, since Sorbifer reduces the absorption of iron. It is necessary to maintain a minimum 2-hour interval between taking these drugs, and with antibiotics (ciprofloxacin, tetracycline, norfloxacin, ofloxacin, doxycycline, etc.) the interval should be at least 3 hours.
Interaction with alcohol
During therapy with Sorbifer, you should refrain from drinking alcohol, since the latter enhances the effect of the active components on the human body.
Overdose
The following symptoms may indicate an overdose of Sorbifer:
- Sudden vomiting.
- Abdominal pain.
- Paresthesia.
- http://www..htmlAcidosis.
- Reduced pressure.
- Pale skin.
- Diarrhea with blood.
- Active heartbeat.
- Hypoglycemia.
- Muscle cramps.
- Kidney failure.
- Hyperthermia.
- Hypoglycemia.
- Coma.
Treatment of these conditions is symptomatic. Gastric lavage, milk consumption and raw egg for binding iron ions. In some cases, deferoxamine is administered.
Use of Sorbifer during pregnancy and lactation
If there are appropriate indications, treatment of pregnant and lactating women with this drug is acceptable and justified.
Sorbifer for newborns and children
The drug is not prescribed to children under 12 years of age.
Storage conditions and shelf life
Sorbifer tablets are stored for 3 years from the date of release in a place inaccessible to children. The optimal temperature is 15-25 degrees.
I drank it during pregnancy, there were no problems, I was recently prescribed to raise hemoglobin and oh, horror. Weakness, blood pressure dropped, she walked and swayed from side to side, although there were no such problems with low hemoglobin. As a result, my stomach ached, as if from poisoning, and terrible diarrhea with vomiting began. I won't drink it anymore.
Fatima
With my low hemoglobin, the pregnancy period became unbearable: constant headaches, drowsiness, terrible condition of my nails, etc. I had to discuss with the doctor the need to take a drug with iron, which could quickly fill the iron deficiency and maintain it at a normal level. The most effective and approved remedy for expectant mothers... With my low hemoglobin, the pregnancy period became unbearable: constant headaches, drowsiness, terrible condition of my nails, etc. I had to discuss with the doctor the need to take a drug with iron, which could quickly fill the iron deficiency and maintain it at a normal level.
The most effective and approved remedy for anemia for expectant mothers, as the doctor told me, is Sorbifer Durules. I started taking it in the second trimester, and also continued vitamin complex for pregnant women with magnesium. It is at this point that I want to emphasize so that they don’t make my mistake.
The fact is that Sorbifer Durules almost always causes a strong by-effect in the form of nausea, but it can be avoided or minimized if you do not drink magnesium complexes.
In general, the product really quickly normalizes the level of iron in the body, and you don’t have to worry about the risk of anemia. It should be taken 40 minutes before or after a meal so that it is absorbed normally and there will be no problems with iron content.
If the tablets irritate the stomach, take them together with Ameprozole. That's what my doctor told me. What I am doing. You will not regret. Be healthy.
Can someone please advise if after taking Sorbifer Durules you experience abdominal pain, feel nauseous, but need to drink it....
I don’t understand people, what difference does it make what kind of stool is from sorbifer? The drug is good, it raises hemoglobin well, there were no side effects from taking it. But for some, the color of the stool is important.
I had a scheduled medical examination at work, and naturally took general tests. Blood showed low hemoglobin and the therapist prescribed taking Sorbifer, one tablet twice a day. The only thing I didn’t like was the taste - you can really feel the aftertaste of iron, but you can’t deny the effectiveness of this drug! It took a month to complete my... I had a scheduled medical examination at work, and naturally took general tests. The blood showed low hemoglobin and the therapist prescribed Sorbifer, one tablet twice a day. The only thing I didn’t like was the taste - you can really feel the aftertaste of iron, but you can’t deny the effectiveness of this drug! It took me a month to bring my indicators up to normal, now I take tests every six months and monitor my iron levels.
I drank sorbifer during lactation, according to a prescription from a gynecologist. Initially, I started taking one tablet twice a day, after two weeks I started taking 2 tablets in the morning and one in the evening for a better effect. A month later, hemoglobin became 132, but was 110.
Thank God, I felt good during pregnancy and everything was fine with the tests, and when I was breastfeeding my daughter I didn’t encounter iron deficiency, but everything didn’t turn out to be so simple. Apparently, due to overwork, I finally developed iron deficiency anemia and I started taking Sorbifer, I saw how it was prescribed... Thank God, I felt good during pregnancy and everything was fine with the tests, and when I was breastfeeding my daughter I didn’t encounter iron deficiency, but everything didn’t turn out to be so simple. Apparently, due to overwork, I finally developed iron deficiency anemia and I started taking Sorbifer, I saw how it was prescribed to girls in consultation, so I bought it. Good remedy, I drank it for a month and my lethargy and irritability disappeared without a trace... But I really haven’t taken tests for hemoglobin yet, not when.
In the middle of pregnancy, I drank Sorbifer, but the stools were dark from it and there was constipation, but my health improved, and the child received the necessary amount of iron. And what they say about the high cost of medicine, I consider nonsense. Similar drugs there is, to raise hemoglobin, but there are no analogues, because Sorbifer contains ascorbic acid and iron,... In the middle of pregnancy, I drank Sorbifer, but the stools were dark from it and there was constipation, but my health improved, and the child received the necessary amount of iron. And what they say about the high cost of medicine, I consider nonsense. There are similar drugs to raise hemoglobin, but there are no analogues, because Sorbifer contains ascorbic acid and iron, which is what it treats iron deficiency anemia, and not its other types. Therefore, I think that its quality justifies the price 100%.
And I felt sick from Sorbifer for several days, but I didn’t stop taking it because the doctor said that it was better to take the drug and give birth to a healthy baby. Gradually unpleasant symptoms passed, probably the body got used to the drug, although I noticed that if I took the medicine during meals and not after, I felt quite normal.... And I felt sick from Sorbifer for several days, but I didn’t stop taking it because the doctor said that it was better to take the drug and give birth to a healthy baby. Gradually, the unpleasant symptoms went away, probably the body got used to the drug, although I noticed that if I took the medicine during meals and not after, I felt quite normal. Regarding hemoglobin, I went to the doctor again, he said that the tests were all good, but better drug drink for preventive purposes.
To say that Sorbifer helped is to say nothing. Well, imagine how you feel when your hemoglobin is around 77. She was pale as a toadstool, she fainted, sleepy all the time, plus absolute apathy. I'm not even talking about crawling home to the second floor, that was a daily feat. Of course, I had to take the drug not... To say that Sorbifer helped is to say nothing. Well, imagine how you feel when your hemoglobin is around 77. She was pale as a toadstool, she fainted, sleepy all the time, plus absolute apathy. I'm not even talking about crawling home to the second floor, that was a daily feat. Of course, I had to take the drug for more than a month or two. I drank it longer, but with breaks so that the body could rest. Now the hemoglobin is already more than a hundred, even though strength has appeared, the face has acquired normal color, yes and emotional condition has improved noticeably.
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