Pyrantel instructions for use. Suspension "Pyrantel" for children: instructions for use. What is the difference between pyrantel embonate and pyrantel pamoate?

In people and animals. It is included in the drugs included in the list of essential medicines " World Organization health care." Tablets and suspensions based on pyrantel are intended for oral administration.

What is the difference between pyrantel embonate and pyrantel pamoate?

Embonate and pamoate are salts of pyrantel that are used as active ingredients in medications. In accordance with the European Pharmacopoeia (collection regulatory documents in pharmacology) produce pyrantel embonate, and the US Pharmacopoeia produces pamoate. No differences in terms of chemical properties There is no effectiveness or treatment regimen between these two types of salts, and they are synonymous.

Description

Each tablet contains 250 mg of active ingredient and auxiliary components (talc, starch, sodium carboxymethyl starch and others). 5 ml of suspension contains 250 mg active substance and additional components (sucrose, flavorings, sorbic acid, etc.).

Operating principle

Pharmacokinetics

Pyrantel has poor absorption from the gastrointestinal tract. This feature reduces the risk of systemic toxicity and reduces the interference of the patient's metabolic processes in breaking down the drug, which could reduce its effectiveness. 1-3 hours after using the drug, the maximum concentration in the blood is reached. Once in the bloodstream, the active substance is distributed throughout the body. Partial conversion to N-methyl-1,3-propanediamine occurs in the liver. About 50% of the drug is excreted unchanged in the feces, a small part is excreted from the body in the urine.

Intended use

Pyrantel is used to treat the following diseases:

There is little activity at . Pyrantel is the active ingredient of drugs used for helminthiasis in humans, and is also used in veterinary medicine.

Human treatment

Pyrantel (tablets, suspension) is taken orally, regardless of food intake. In order to make the reception less unpleasant, it is recommended to mix the product with fruit juice or a glass of milk. Before this, you do not need to adhere to a specific diet or take a laxative. The dosage is determined individually for the patient and depends on his body weight, age, and degree of invasion. In most cases, a single dose is required.

Treatment regimen for ascariasis and enterobiasis

A child from 6 months to 3 years requires 125 mg of the drug, which is equivalent to 1 half of a tablet or 0.5 scoop of suspension. Although it should be remembered that at this age the drug is not recommended for use.

For children from three to six years old, 250 mg of the drug (1 tablet or 1 spoon of suspension) is prescribed.

Children from 6 to 12 years old use 500 mg of the drug. This amount is contained in 2 tablets or 2 tablespoons of suspension.

Adults weighing less than 75 kg and children over 12 years of age take 750 mg of the drug (3 tablets or 3 tablespoons of suspension). Patients weighing more than 75 kg use 1000 mg (4 tablets or 4 tablespoons of suspension).

*Measuring spoons with a capacity of 5 ml are included in the package along with the drug, released in the form of a suspension.

**One tablet contains 250 mg of active substance (pyrantel).

According to more precise recommendations, for ascariasis or enterobiasis, the medicine is taken once according to the regimen of 9 mg per 1 kg of the patient’s weight. With a slight degree of invasion, the doctor may prescribe a minimum dosage, which reaches 5 mg per 1 kg of the patient’s body weight.

Treatment regimen for hookworm and necatoriasis

To get rid of hookworm, it is advisable to take 10 mg per 1 kg of body weight once a day. The therapeutic course is 3 days.

For severe forms of necatoriasis, use 20 mg per 1 kg of weight for two days.

In case of overdose of the drug, it is necessary to rinse the stomach. There is no specific antidote.

Animal treatment

In veterinary practice, pyrantel is used in the treatment of dogs, cats and other domestic animals. It is also prescribed for the treatment of horses and, less commonly, pigs, sheep, and cattle. But pyrantel is not the best remedy for the treatment of animals in terms of effectiveness, although due to its relatively low toxicity its use may be justified.

To treat animals, it is necessary to accurately determine the dosage of the drug. If you prescribe an insufficient amount of the drug, the required effectiveness will not be obtained. In case of overdose, possible Negative consequences for an animal.

Pyrantel effectively rids animals of gastrointestinal nematodes. When compared with other drugs used in veterinary medicine against helminths, this drug has practically no effect negative impact. The dose of the medicine is selected taking into account the weight of the animal. The larger it is, the less amount of the drug is used per 1 kg of body weight. Yes, for adult dog, whose weight is more than 2.5 kg, about 5 mg/kg is used. Puppies and small dogs weighing up to 2.5 kg should be given approximately 10 mg/kg of the active substance. For cats, the dosage is the same. Although the instructions for tablets or suspension usually indicate more high dose, often even 2 times or more.

Pyrantel is part of the complex treatment of oxyurosis in horses. The average dose is 5 mg per 1 kg of weight. For the treatment of ascariasis and enterobiasis, as a rule, a single dose is sufficient. If mixed helminthiasis is diagnosed, a dosage of 10 mg per 1 kg of animal weight is prescribed.

The exact dosage of pyrantel for animals should be looked at on the packaging, since various drugs contains different amounts of active ingredient. In addition, in veterinary medicine, especially for cats and dogs, in addition to pyrantel, there is often another active substance in the composition.

Side effects and contraindications

In many cases, during the period of taking pyrantel, if the dosage is correctly selected, side effects are not observed. Sometimes signs of liver failure appear. Patients in some cases report nausea, diarrhea, loss of appetite, vomiting, pain in the abdomen and stomach. Undesirable effects can be observed from the central nervous system - headaches, insomnia, dizziness, increased drowsiness, which also disturbs during the daytime. Sometimes auditory perception is affected. In rare cases, signs appear allergic reactions, confusion occurs, hallucinations are observed. Patients may complain of increased body temperature.

It is not recommended to take Pyrantel for people suffering from liver failure. It is also undesirable to use it in patients who have an individual intolerance to the drug containing this active substance.

During pregnancy, breastfeeding and children

Information about the penetration of the drug through the placenta and into breast milk has not been refuted. In this regard, pregnant and lactating women are not recommended to take pyrantel. Exceptions are cases where the risk to the mother outweighs the risk to the child. In this case, treatment should only take place under the supervision of a doctor. During the period of therapy it is necessary to stop breastfeeding. It is not recommended to use a drug based on pyrantel to treat children under three years of age.

Interaction with other drugs

And when taken simultaneously with pyrantel, the effect of the drug is weakened. Therefore not recommended complex treatment these drugs. Pyrantel can also increase theophylline levels in the blood if used simultaneously with levamisole and piperazine.

special instructions

The dosage of pyrantel should only be determined by a doctor. It is set depending on the individual characteristics of the body, the severity of the disease, the weight and age of the patient. Self-medication is not recommended. Otherwise, the risk of undesirable consequences increases.

After taking the drug, no laxative is prescribed. When treating helminths, especially enterobiasis, all members of the patient’s family are treated simultaneously. When the course is completed, stool tests should be ordered to determine the presence or absence of worm eggs in it. During treatment and several weeks after it it is necessary Special attention pay attention to personal hygiene. This includes wet cleaning of the room where the patient lives, timely trimming of nails, hand washing, etc.

Trade names and prices

This active substance is part of such anthelmintic drugs as Helmintox, Nemotsid, Pirantel. The country of origin can be India, France, England, and you can also find domestic analogues.

Despite its high efficiency, the product has an acceptable cost. In Russia, Ukraine and other CIS countries, tablets can be purchased at a price of approximately 0.4-0.5 dollars. for 750 mg of the drug - this will be one dose for an average adult. The suspension is sold a little more expensive, its cost in pharmacies starts from about 0.9 dollars. The price of the drug greatly depends on the manufacturer and the region where sales are made.

In veterinary medicine, a fairly well-known drug containing pyrantel as an active substance is Pyraprasit. It happens different types and may contain not only pyrantel as an active substance, but also other components, for example, febantel.

In this article you can find instructions for use medicinal product Pirantel. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Pirantel in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications were observed and side effects, perhaps not stated by the manufacturer in the annotation. Pyrantel analogues in the presence of existing structural analogues. Use for the treatment of worms (ascariasis, enterobiasis and other pathogens) in adults, children, as well as during pregnancy and lactation.

Pirantel- anthelmintic agent acting on nematodes.

Causes a neuromuscular blockade in helminths sensitive to it, which facilitates their removal from digestive tract without exciting or stimulating the migration of affected worms.

Pyrantel is effective against infestations caused by pinworms (Enterobius vermicularis), hookworms (Ancylostoma doudenale, Necator americanus), against pathogens of trichocephalosis (Trichostrongylus orientalis and Trichostrongylus colubriformis) and ascariasis (Ascaris lumbricoides).

Pharmacokinetics

Pyrantel is very poorly absorbed from gastrointestinal tract(Gastrointestinal tract). There is no data regarding the penetration of the drug through the placenta and into the milk of a nursing woman, as well as regarding the distribution of the drug in tissues and body fluids (theoretically, drug resorption is minimal). About 93% of an oral dose of the drug is excreted unchanged by the intestines, and no more than 7% is excreted by the kidneys unchanged or as a metabolite of N-methyl-1.3-propanediamine.

Indications

• ascariasis;
• enterobiasis;
• hookworm disease;
• necatoriasis;
• trichocephalosis.

Release forms

Tablets 250 mg.

Suspension for oral administration (sometimes mistakenly called syrup).

Instructions for use and dosage

The drug is used during or after meals, chewing the tablet thoroughly with 1 glass of water.

Unless another treatment regimen is prescribed, depending on the patient’s age and body weight, the following dosages (tablets and suspension) are recommended:

1. 3-6 years - 1 tablet 1 time per day - 1 scoop = 5 ml;
2. 6-12 years - 2 tablets 1 time per day - 2 scoops = 10 ml;
3. over 12 years of age and adults weighing up to 75 kg - 3 tablets 1 time per day - 3 scoops = 15 ml;
4. adults weighing more than 75 kg - 4 tablets 1 time per day - 4 scoops = 20 ml.

To avoid self-infection, the course may be repeated 3 weeks after the first dose.

For hookworm disease, combination of necatoriasis with ascariasis or other combined helminth infections, Pirantel is used for 3 days at 10 mg/kg per day.

For massive infestations of Necator americanus, a dose of 20 mg/kg body weight is recommended for 2 days.

Side effect

• nausea, vomiting;
• lack of appetite;
• diarrhea;
• stomach pain and cramps;
• headache;
• dizziness;
• drowsiness or insomnia;
• weakness;
• rash;
• elevated temperature;
• hearing impairment;
• hallucinations with confusion and paresthesia (the connection of these symptoms with taking the drug has not been proven).

Contraindications

• hypersensitivity to the drug;
• myasthenia gravis (treatment period);
• children under 3 years of age (for this dosage form).

Use during pregnancy and breastfeeding

There are no controlled studies of the use of Pyrantel in pregnant women, so the drug should be used only if the potential benefit to the mother outweighs the possible risk to the fetus.

There is no data on the safety of the drug in lactating women, so the issue of discontinuation should be addressed. breastfeeding during drug treatment.

special instructions

Considering possible side effects from nervous system When using the drug, caution must be exercised when engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Drug interactions

Pyrantel should not be used together with piperazine. These drugs act antagonistically.

Pyrantel increases plasma theophylline concentrations.

Analogues of the drug Pirantel

Structural analogues of the active substance:

• Helminthox;
• Nemocid;
• Pyrantela pamoate.

Analogs for the antihelminthic effect:

• Biltricide;
• Vermox;
• Vero-Mebendazole;
• Vormin;
• Gelmodol-VM;
• Dekaris;
• Centaury grass;
• Mebendazole;
• Medamina tablets 0.1 g;
• Nemozol;
• Tansy flowers;
• Piperazine;
• Piperazine adipate;
• Pyrvinium;
• Sanoxal;
• Telmox 100;
• Pumpkin seeds.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Pyrantel is a fairly effective remedy, the main effect of which is to block the neuromuscular system of helminths.

In this article we will look at why doctors prescribe Pirantel, including instructions for use, analogues and prices for it medicine in pharmacies. Real REVIEWS of people who have already used Pirantel can be read in the comments.

Composition and release form

Clinical and pharmacological group: anthelmintic drug.

1. Pyrantel yellow viscous suspension for oral use 50 mg/ml. Each 5 ml of suspension contains: active substance – pyrantel pamoate 250 mg. Excipients: sodium methylparaben, sodium propylparaben, sodium saccharin, sodium chloride, sodium citrate, sucrose, lemon acid, sodium carboxymethyl cellulose, sorbitol 70%, polysorbate 80 (Tween 80), chocolate essence and purified water.
2. Pyrantel tablets are yellow, capsule-shaped, uncoated tablets with a division line on one side. The active substance is pyrantel pamoate 250 mg. Excipients - starch, gelatin, gum acacia, methylparaben, propylparaben, sodium starch glucolate, talc, magnesium stearate, colloidal silicon dioxide (aerosil).

What is Pirantel used for?

The drug Pirantel is prescribed for the following types of helminthiasis:

1. Enterobiasis (pinworms).
2. Ascariasis.
3. Nekatoroz.
4. Ankylostomiasis.

1. Frequent allergies.
2. Lethargy, anemia.
3. Digestive and stool disorders.
4. Lack of appetite, which leads to noticeable weight loss.

In addition, children whose bodies are affected by helminths may lag behind in physical development. If left untreated for a long time, the disease develops into severe form, which leads to a gradual lag in mental development.

pharmachologic effect

1. Patients with ascariasis and enterobiasis are prescribed an average dose of 10–12 mg per 1 kg of weight in one dose. Children after 6 months should receive syrup at a dose of 2.5 ml per 10 kg of weight in one dose. Adult patients (up to 75 kg) receive 15 ml per dose. If a person’s weight exceeds 75 kg, you need to drink 20 ml of the product at one time.
2. For patients with hookworm in endemic areas or with severe infestation, the drug is prescribed based on a dosage of 20 mg per 1 kg of weight for 2 or 3 doses, treatment lasts 2-3 days.

The dosage per day is calculated as follows:

• children after 6 months receive 5 ml of syrup per 10 kg of weight;
• with a weight of up to 75 kg - 30 ml of syrup per day;
• with a weight of 75 kg - 40 ml of syrup per day.

The dose of the drug depends on the type of invasion, as well as the age of the patient. When using Pyrantel in tablet form, the following dosages are recommended:

• for children from 3 to 6 years – 250 mg (one tablet);
• for children over 12 years old – 500 mg (two tablets);
• children over 12 years of age and adults weighing no more than 75 kg are prescribed 750 mg (3 tablets);
• adult patients weighing over 75 kg are prescribed 1000 mg (4 tablets).

Contraindications

If contraindications to these medications are found, then they should not be used. In this case, the doctor must select a suitable analogue.

Contraindications include the following factors:

• detection of Crohn's disease;
• liver failure and disorders of secretory function;
• nonspecific ulcerative colitis;
• disorders of the central nervous system;
• oncological diseases, tumors of internal organs;
• blood diseases.

It is also better to avoid taking all anthelmintic drugs during pregnancy or lactation.

Adverse reactions

When using the suspension, reactions may develop from several systems of the patient’s body:

1. Nervous system (headache, sleep disturbances, fatigue, weakness, dizziness).
2. Sense organs (hearing impairment, paresthesia, hallucinations, impaired consciousness).
3. Gastrointestinal tract (anorexia, vomiting, diarrhea, painful sensations in the abdominal area, tenesmus, nausea).
4. Liver (increased secretion of liver enzymes).
5. Skin (hives, rash, fever).

In some cases, there is a decrease in performance and increased fatigue.

Pregnancy and lactation

The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Analogs

Analogues of this product are the drugs Nemotsid, Helmintox, Pyrantel pamoate, which contain a similar active ingredient. The drugs Vermox, Biltricid, Vormin, Dekaris, etc. have a similar effect on the body.

Prices

The average price of PIRANTEL, suspension in pharmacies (Moscow) is 35 rubles. Tablets cost 22 rubles.

Content

The anthelmintic drug Pyrantel paralyzes and destroys helminths. The drug is well tolerated by the body, but before starting the course, consultation with your doctor is necessary. Self-medication is contraindicated.

Composition of Pyrantel

There are 2 dosage forms– tablets and suspension for oral use. Liquid yellow color with a specific odor is poured into 15 ml dark glass bottles. Yellow flat-cylindrical tablets have a score on one surface. The polymer jar contains 3 or 6 pcs. Chemical composition:

Pyrantel is poorly absorbed from the digestive tract. The maximum plasma concentration is reached after 1–3 hours. Metabolized in the liver with the release of the main metabolite - K-methyl-1,3-propanediamine. It is partially excreted from the body with bile, the main concentration (about 70%) is excreted in urine.

Indications for use of Pirantel

The action of the medication is aimed at the productive extermination of helminths. Medical indications for use include the following diseases:

• ascariasis;
• necatoriasis;
• enterobiasis;
• hookworm disease.

How to take Pirantel

Both forms of release are intended for oral administration. Children are often prescribed a suspension, while adult patients are prescribed tablets. According to the instructions, Pirantel should be taken before or during meals. The tablet must be chewed and washed down with plenty of water. The course of treatment depends on the form of release of the medicine, individual recommendations specialist, diagnosis.

Suspension

For ascariasis and enterobiasis, the average therapeutic dose is 10–12 mg per 1 kg of child weight. Patients older than 6 months are prescribed 2.5 ml per 10 kg of weight in one go. The dosage for adult patients weighing up to 75 kg is 15 ml per dose. With a body weight of 75 kg and above, you need to drink 20 ml of Pirantel suspension per day. To consolidate the results obtained, doctors recommend taking a second course after a 3-week break. The dosage for severe infestation is 20 mg per 1 kg of weight, divided into 3 doses. The duration of the course of treatment is 2–3 days.

The daily dosage of the medicine is determined by the weight and age of the patient. Recommended doses are indicated in the instructions:

• patients 2–6 years old – 250 mg;
• 6–12 years - 500 mg;
• from 12 years and adult patients weighing up to 75 kg - 750 mg;
• adults weighing over 75 kg - 1,000 mg.

special instructions

For enterobiasis, doctors prescribe 1 tablet. once. Afterwards, the patient is required to re-take a stool test for worm eggs and scrapings from the perianal folds. To prevent re-infection, it is necessary to wash the patient’s underwear and iron them on both sides. In addition, it is required to carry out wet cleaning daily and wash dishes with an alkaline solution. Other recommendations are described in the instructions for use:

During pregnancy

When carrying a fetus, the medication is prescribed extremely rarely - only in the 3rd trimester on the recommendation of a doctor. Active ingredients penetrate the placental barrier, but their effect on the fetus is not specified. Clinical studies have not been conducted in pregnant patients. When treating with Pyrantel during lactation, it is necessary to urgently raise the issue of temporarily stopping breastfeeding, since the medicine is excreted in breast milk.

Pyrantel for children

IN childhood Pyrantel anti-worm suspension is more often prescribed, which has pleasant taste, does not cause disgust. Recommended dosages are described in the instructions. If necessary, the child is prescribed Pirantel tablets, but before use, pediatricians advise crushing the prescribed dose into powder.

Drug interactions

In combination with Levamisole, there is a potentiation of the toxic effect of the latter, and the level of Theophylline in the blood increases. The simultaneous use of the suspension with Piperazine, an antagonist of the anthelmintic effect of Pirantel, is prohibited. Other information about drug interactions not included in the instructions.

Side effects

During treatment with Pirantel, doctors do not rule out the occurrence of side effects that affect important internal organs, systems. Possible complaints patient:

• from the digestive tract: nausea, vomiting, lack of appetite, anorexia, diarrhea, recurrent abdominal cramps, increased levels of liver enzymes;
• from the nervous system: dizziness, migraine attacks, insomnia, drowsiness;
• skin covering: small rash, itching, hyperemia of the epidermis, urticaria;
• other: feeling of weakness, increased fatigue.

Overdose

If the prescribed doses of Pirantel are systematically exceeded, the patient's well-being worsens. Symptoms of overdose: nausea, diarrhea, anorexia, vomiting, dizziness, visual hallucinations. For intoxication, there is no specific antidote. The patient needs to rinse the stomach, take intestinal sorbents, then carry out symptomatic treatment as indicated (monitor respiratory function, cardiac activity).

Contraindications

Pyrantel tablets and suspensions are contraindicated for use if the body is hypersensitive to the components included in the drug. Other medical restrictions:

• liver failure;
• renal failure;
• intestinal obstruction;
• age up to 6 months;
• myasthenia gravis;
• pregnancy;
• lactation.

Terms of sale and storage

Pirantel anti-worm suspension and tablets are available with a prescription. The medicine must be stored in a dry, cool and dark place at temperatures up to 25 degrees. Keep away from contact with children, avoid direct contact sun rays. Shelf life – 3 years. An opened bottle of suspension can be stored for no more than 4 weeks.

Analogs

If the medicine does not suit you medical contraindications or calls side effects, you need to choose an analogue. Reliable substitutes for Pyrantel and their brief characteristics.

Included drug in tablets contains active ingredient pyrantel , as well as additional components: methyl parahydroxybenzoate, gelatin, acacia gum, starch, sodium carboxymethyl starch, talc, magnesium stearate, propyl parahydroxybenzoate, colloidal silicon dioxide.

Pyrantel suspension contains the active component pyrantel, as well as additional components: sucrose, xanthan gum, sorbic acid, polysorbate 80, methyl parahydroxybenzoate, solution 70%, propyl parahydroxybenzoate, flavorings, purified water.

Release form

Produced suspension And Pirantel tablets.

The suspension is a homogeneous yellow mass. Contained in dark glass bottles of 15 ml.

The tablets are flat-cylindrical with a chamfer and a line on one side. Yellow tablets. There can be 3 or 6 tablets in a polymer jar.

pharmachologic effect

Pharmacokinetics and pharmacodynamics

After entering the gastrointestinal tract pyrantel pamoate absorbed very poorly. Plasma concentrations are not significant and range from 0.05 to 0.13 mg/ml and are achieved within 1 to 3 hours. Partial occurs in the liver, the main one is K-methyl-1,3-propanediamine.

The main part of the active substance is excreted from the body in feces, approximately 7% in urine.

Indications for use

Pirantel suspension and tablets for worms are prescribed for the following diseases:

• necatoriasis

Contraindications

There are the following contraindications for using the product:

• high level of sensitivity to pyrantela and any other components of the product;
• liver failure ;
• child's age up to 6 months.

Side effects

During treatment, the following side effects may occur:

• nervous system : , , ;
• digestive system : vomiting, periodic abdominal cramps, anorexia , tenesmus;
• skin and subcutaneous tissue : , rash;
• hepatobiliary system : increased liver levels;
• other manifestations : feeling of weakness, increased fatigue.

Instructions for use of Pirantel (Method and dosage)

The product is used according to doctor's indications.

Pyrantel suspension, instructions for use

The suspension for children is used according to indications; it must be shaken before taking. Patients with ascariasis and enterobiasis are prescribed an average dose of 10–12 mg per 1 kg of weight in one dose. Children after 6 months should receive syrup at a dose of 2.5 ml per 10 kg of weight in one dose. Adult patients (up to 75 kg) receive 15 ml per dose. If a person’s weight exceeds 75 kg, you need to drink 20 ml of the product at one time.

To improve the effectiveness of the treatment of enterobiasis, you should very carefully adhere to all the rules of personal hygiene. It is recommended to conduct another course of therapy after three weeks.

For patients with hookworm in endemic areas or with severe infestation, the drug is prescribed based on a dosage of 20 mg per 1 kg of weight for 2 or 3 doses, treatment lasts 2-3 days.

The dosage per day is calculated as follows:

• children after 6 months receive 5 ml of syrup per 10 kg of weight;
• with a weight of up to 75 kg - 30 ml of syrup per day;
• with a weight of 75 kg - 40 ml of syrup per day.

Subject to mild invasion Ankylostoma duodenale sometimes it is enough to take a dose of 10 mg per 1 kg once.

Pirantel tablets, instructions for use

Adults are usually prescribed Pirantel in tablets. It should be taken before or during the use of food. The tablet is chewed and washed down with plenty of liquid.

How to take Pirantel for children depends on their body weight and age:

• at the age of 2-6 years, 250 mg of the drug is indicated;
• at the age of 6-12 years - 500 mg;
• children over 12 years of age and adult patients weighing up to 75 kg - 750 mg;
• adults whose weight exceeds 75 kg - 1000 mg.

If only infection with a human nematode is noted, you should take Pyrantel 5 mg per 1 kg of weight in one tablet.

For patients with enterobiasis and ascariasis, as well as with mixed infestations, the dose intended for the entire course is administered once (10 mg per 1 kg).

Patients with hookworm disease are advised to take the same dose for three days.

In case of massive infestations of Necator americanus, a dose of 20 mg/kg is indicated for two days.

You should ask your doctor for more information about how many days to take the drug, how to take tablets and suspension for adults and children for treatment, as well as for prevention for adults and children.

Overdose

In case of an overdose of the drug, the patient may experience the following negative manifestations: nausea, vomiting, anorexia . But it should be borne in mind that pyrantel is poorly absorbed in the body, which is why symptoms appear very rarely even with a significant overdose. If there is such a need, gastric lavage is prescribed; there is no specific one. It is important to control the functions of blood vessels, heart, and respiratory system.

Interaction

Treatment with Pirantel should not be prescribed simultaneously with the use of , since in this case there may be a potentiation of the toxic effect of Levamisole, the plasma level also increases .

Tablets and suspension cannot be used simultaneously with Piperazine, since this drug is an antagonist of the anthelmintic effect of Pirantel.

Terms of sale

You can purchase Pirantel with a doctor's prescription.

Storage conditions

When storing, keep away from light and exposure high temperatures. Once the bottle has been opened, it can be stored for no more than 4 weeks.

Best before date

Pyrantel can be stored for 3 years

special instructions

The drug is prescribed with caution to people who have impaired liver function. During therapy, you should not abstain from eating or take laxative medications. This does not determine how quickly the drug works.

The drug is prescribed for simultaneous administration to all members of the family who live together. You should consider how to give the suspension or tablets to your child and follow the instructions. After completion of the study, the patient's stool is examined.

To prevent re-infection, it is important to carefully adhere to hygiene rules.

Sometimes during treatment there may be Withweakness, dizziness . This should be taken into account when driving or when working with precision mechanisms.

The drug is not prescribed to people undergoing treatment. myasthenia gravis .

How long the drug takes to work depends on the diagnosis and the individual characteristics of the course of the disease.

Which is better: Decaris or Pirantel?

Dekaris - an antihelminthic agent that has a similar effect. The drug Dekaris has more contraindications, side effects are almost the same as when using Pirantel. It is believed that Pirantel is more preferable for treating children.

Which is better: Vermox or Pyrantel?

– this is PM wide range actions. It is especially effective against enterobiasis and trichocephalosis. Which of the two drugs is preferred should be determined taking into account individual characteristics.

Nemozol or Pirantel: which is better?

Pyrantel for children

Reviews about Pirantel for children left by parents are mostly positive. However, it must be taken into account that the instructions for the suspension for children stipulate that the drug is not prescribed to children under 3 years of age. It is important to strictly follow the instructions on how to take the suspension. The dosage for children must be carefully maintained.

With alcohol

Pyrantel in the form of suspension and tablets should not be combined with alcoholic beverages.

During pregnancy and lactation

You can use this medicine only according to strict indications, carefully weighing the benefits for the expectant mother and the harm to the fetus. The drug is not used during.

Reviews of Pirantel

Pirantel price, where to buy

The price of Pirantel suspension 15 ml is, on average, 60 rubles. The cost may be slightly lower or higher. The price of Pyrantel tablets depends on the packaging and manufacturer. On average, buy a pack of 3 tablets. can be priced from 20 to 40 rubles. How much this drug costs in pharmacies should be asked directly at the point of sale.

• Online pharmacies in Russia Russia
• Online pharmacies in Ukraine Ukraine
• Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

Pyrantel tablets 250 mg No. 3 Ozone Ozone LLC

Pyrantel tablets 250 mg No. 3 Polpharma Polpharma

Pyrantel Susp. internal 250mg/5ml 15mlMedana Pharma Terpol Group Joint Stock Company

Pyrantel Susp. internal 250mg/5ml 15ml n1 Ozone LLC