Glutamic acid - what it is, composition, why it is used in sports, bodybuilding. Preparations and products containing acid, and how to take them. Glutamic acid - instructions for use. Glutamic acid in foods or preparations for sports K

Glutamic acid

Composition and release form of the drug

◊ Film-coated tablets white or white with a barely noticeable yellowish tint, round, biconvex; On a cross section, two layers are visible.

Excipients: potato starch 28.1 mg, 8.4 mg, talc 6 mg, calcium stearate monohydrate 2.4 mg.

Film shell composition: sucrose 89.305 mg, talc 3.933 mg, titanium dioxide 2.573 mg, povidone 2.018 mg, colloidal silicon dioxide 2.115 mg, beeswax 0.028 mg, liquid paraffin 0.028 g.

10 pieces. - contour cellular packaging (aluminum/PVC) (6) - cardboard packs.
60 pcs. - polymer jars (1) - cardboard packs.

pharmachologic effect

A drug that improves brain metabolism. An essential amino acid plays the role of a mediator with high metabolic activity in the brain, stimulates redox processes in the brain and protein metabolism. Normalizes metabolism, changing the functional state of the nervous and endocrine systems. Stimulates the transmission of excitation in the synapses of the central nervous system, promotes neutralization and removal from the body, increases the body's resistance to hypoxia.

It is one of the components of myofibrils, participates in the synthesis of other amino acids, acetylcholine, ATP, urea, promotes the transfer and maintenance of the required concentration of potassium ions in the brain, serves as a link between the metabolism of carbohydrates and nucleic acids, and normalizes the content of glycolysis indicators in the blood and tissues. It has a hepatoprotective effect and inhibits the secretory function of the stomach.

Pharmacokinetics

Absorption is high. Penetrates well through histohematic barriers (including through the BBB), cell membranes and membranes of subcellular formations. Accumulates in muscle and nervous tissues, liver and kidneys. Excreted by the kidneys - 4-7% unchanged.

Indications

Included complex therapy: (mainly minor seizures with equivalents), schizophrenia, psychoses (somatogenic, intoxicating, involutional), reactive depressive state, mental exhaustion, insomnia, consequences of meningitis and encephalitis, depression, progressive myopathy; delay mental development of various etiologies, cerebral palsy, consequences of intracranial birth trauma, poliomyelitis (acute and recovery period), Down's disease; toxic neuropathy due to the use of isonicotinic acid hydrazides (including).

Contraindications

Feverish conditions, hepatic and/or renal failure, suppression of bone marrow hematopoiesis, anemia, increased excitability, violent mental reactions, peptic ulcer stomach and duodenum, nephrotic syndrome, obesity, increased sensitivity to glutamic acid.

Dosage

Adults - 1 g 2-3 times/day. Children under 1 year - 100 mg, up to 2 years - 150 mg, 3-4 years - 250 mg, 5-6 years - 40 mg, 7-9 years - 500 mg-1 g, 10 years and older - 1 g 2-3 times/day. For oligophrenia - 100-200 mg/kg for several months. Take orally 15-30 minutes before meals, if dyspeptic symptoms develop - during or after meals. The course of treatment is from 1-2 to 6-12 months.

Side effects

Maybe: vomit, loose stool, central nervous system stimulation, allergic reactions, abdominal pain, nausea, increased excitability.

Content

Well known to many athletes and people who lead healthy image life, the neurotransmitter glutamine amino acid, is an amino acid replaceable for the human body, but very important in many metabolic processes, especially proteins. Tablets containing this neurotransmitter are also used to treat a number of central nervous system diseases.

What is glutamic acid

The chemical formula of glutamic acid contains two double bonds, which indicate that this compound easily reacts with many organic substances: this dicarboxylic acid is capable of removing dangerous toxic metabolic products such as ammonia. The effect and role of glutamate (a salt of the glutamic amino acid) for the human body cannot be overestimated, because as a neurotransmitter it participates in the conduction of nerve impulses and volumetric neurotransmission, in addition this substance is involved in the development of the brain.

What foods contain glutamic acid?

The neurotransmitter glutamic acid (designated as E620) is found in proteins, phosphatides in a free state and in the form of salts that are better absorbed: ammonium glutamate E624, potassium glutamate E622, calcium diglutamate E623, monosodium glutamate E621, magnesium glutamate E625. Free glutamic acid is found in the following natural products:

• green pea;
• corn;
• Green pepper;
• eggs;
• beef;
• fatty fish (mackerel, mackerel, cod, trout);
• spinach;
• tomatoes;
• cheese, milk;
• carrots, beets.

The modern food industry cannot do without the use of glutamine as food additives into products instant cooking, semi-finished products, ready-made culinary products, broth concentrates, deli meats, boiled sausages. The popular dicarboxylic acid is used as a flavor enhancer - it gives products a pronounced meaty taste, enhances the aroma of meat, stimulates appetite and can be addictive.

Glutamic acid - instructions

You can find medications containing glutamine at the pharmacy and take it for the purposes you need. But it is important to remember that an excess of such a substance can provide the opposite effect to the expected effect: accumulating in the intercellular space, leads to early death of nerve cells, and also causes obesity, problems with the heart and metabolic processes. The instructions for glutamic acid contain information about the required dosage, indications and contraindications for use, which is important to read before starting use.

Glutamic acid - indications for use

Important structural element nitrogen metabolism, the “stimulating” amino acid has its own indications and contraindications. In medicine it is used to treat diseases of the central nervous system; indications for the use of glutamic acid may be:

• schizophrenia;
• depression;
• epilepsy;
• consequences of meningitis, encephalitis;
• nervous exhaustion;
• psychoses;
• protein metabolism disorder;
• myopathy.

How to take glutamic acid

The release form of glutamine is film-coated tablets with different dosages, powder. Before starting treatment, read the instructions on how to take glutamic acid. This medicine is prescribed by a doctor after an examination and, depending on the disease, the course of treatment can range from 2 months to a year. Take tablets before or during meals, and the dosage of the drug depends on the diagnosis, age and weight of the person:

• infants up to one year of age – 100 mg;
• 1-2 years – 150 mg;
• 3-4 years – 250 mg;
• 5-6 years – 400 mg;
• 7-9 years – 500 mg;
• 10 years and older – 1000 mg.

Glutamic acid - contraindications

Athletes and people who are trying to lose weight prescribe amino acids on their own, but such actions can be dangerous for your body, because, like others medicines There are contraindications for glutamic acid. After identifying symptoms that you think can be eliminated with this drug, you should not self-medicate. In most cases, the amino acid described above can be completely synthesized by the body and supplied with food, but the harm from self-medication with it can be significant if you have:

• obesity;
• renal, liver failure;
• increased excitability;
• stomach ulcer;
• anemia;
• nephrotic syndrome;
• fever;
• suppression of bone marrow hematopoiesis.

Glutamic acid in sports

There are acids that are replaceable for the body an indispensable assistant for people involved different types sports Glutamic acid is useful for athletes because it facilitates pain syndrome in muscles after training, removing decay products from tissues, making muscle fibers more susceptible to the penetration of potassium into them. Glutamic acid in bodybuilding helps to quickly gain muscle mass, and due to the ability to accelerate protein metabolism and remove ammonia, the need for glutamine for bodybuilders is much higher than for other people.

Glutamic acid for weight gain

Glutamic acid alone will not help with weight gain, but not a single course of weight gain muscle mass shouldn't go without it. Why is glutamine so important? The first thing that is important when gaining weight is stimulation of metabolism, and for this the cells need good food spectrum of amino acids, and converts glutamine into other amino acids quickly and efficiently. In addition to accelerating metabolic and oxidative processes, a non-essential amino acid can improve immunity and make the process of weight gain healthy.

Glutamic acid for children

L-glutamine is one of the few drugs that can be prescribed to a child under one year of age. The drug helps to cope with many serious childhood illnesses and disorders. Glutamic acid is prescribed to children for:

• oligophrenia;
• Down's disease;
• consequences of birth intracranial injury;
• mental retardation;
• cerebral palsy;
• polio.

Glutamic acid price

Order inexpensively this drug You can visit online pharmacies by studying product catalogs. According to reviews, it is easy to buy large volumes of L-glutamine for sports purposes in an online store. The price of glutamic acid varies from 15 to 75 rubles per package of tablets with a dosage of 250 mg (10 pcs.). The cost of specialized sports nutrition preparations containing glutamine does not compare favorably with pharmacy products, the price of which is tens of times lower.

Video

Glutamic acid - reviews

Irina, 25 years old A gynecologist prescribed a course of this amino acid to me when I was planning a pregnancy. Before drinking, I studied reviews on the Internet, most of which were positive. During the reception I did not feel any side effects, and after the full course menstrual cycle became much more stable, without delays.

Alina, 28 years old My husband is involved in bodybuilding and he drinks L-glutamine almost constantly. He orders the drug in pharmacies, and not on sports nutrition websites - everything is very expensive there, and no difference in composition was found. His trainer advised him to take the drug, side effects I haven’t had one since I started, so I’m not worried about my husband’s health.

Margarita, 40 years old When, due to serious problems at work, I went to a neurologist, it turned out that I had serious nervous exhaustion, vegetative-vascular dystonia, lost on nervous soil almost 7 kg. I was treated with antidepressants and was prescribed many more vitamins and glutamic acid, which I still take on the doctor’s recommendation to gain weight.

Attention! The information presented in the article is for informational purposes only. The materials of the article do not call for self-treatment. Only a qualified doctor can make a diagnosis and give treatment recommendations based on the individual characteristics of a particular patient.

Discuss

Glutamic acid - instructions for use. Glutamic acid in foods or sports preparations

Formula: C5H9NO4, chemical name: L-Glutamic acid.
Pharmacological group: neurotropic drugs/nootropics;
Metabolics/Proteins and Amino Acids/Essential Amino Acids; means for parenteral and enteral nutrition; detoxifying agents, including antidotes.
Pharmachologic effect: stimulating metabolism in the central nervous system, neurotransmitter.

Pharmacological properties

Glutamic acid is a non-essential amino acid that can enter the body with food, and can also be synthesized in the body during protein catabolism during transamination. Participates in carbohydrate and protein metabolism, prevents a decrease in redox potentials, stimulates oxidation processes, increases the body's stability during hypoxia. Glutamic acid normalizes metabolism by changing functional state endocrine and nervous systems. It is also a neurotransmitter amino acid that stimulates central nervous system transfer of excitation. Participates in the formation of other amino acids, ATP, acetylcholine, helps in the transfer of potassium ions, improves the functioning of skeletal muscles (it is one of the components of myofibrils). Glutamic acid has detoxification properties, promotes the removal and neutralization of ammonia in the body. Improves glycolysis processes in tissues, reduces secretion in the stomach, and has a hepatoprotective effect. When used orally, it is well absorbed and penetrates cell membranes and the blood-brain barrier. It is utilized during metabolism and 4–7% is excreted unchanged by the kidneys. The effectiveness of combined use with glycine or pachycarpine for progressive myopathy has been obtained.

Indications

Epilepsy (especially with petit mal seizures with equivalents); psychoses (intoxication, somatogenic, involutional); schizophrenia; reactive states that occur with symptoms of exhaustion; consequences of encephalitis and meningitis; depression; hepatic coma; toxic neuropathy when taking isonicotinic acid hydrazides (together with pyridoxine and thiamine); in pediatrics for mental retardation, cerebral palsy, consequences of birth intracranial trauma, Down's disease, polio (recovery and acute periods).

Method of use of glutamic acid and dose

Glutamic acid is taken orally 15–30 minutes before meals. Children over 10 years old and adults 2 – 3 times a day, 1 g; for children: ; 7–9 years - 0.5–1 g, 2–3 times a day; 5–6 years - 0.4 g; 3–4 years - 0.25 g; 1–3 years - 0.15 g; up to 1 year - 0.1 g; for oligophrenia - 0.1–0.2 g/kg. Duration of therapy is from 1–2 to 6–12 months.
If you miss the next dose of glutamic acid, take it as you remember, then take glutamic acid after the time specified by the doctor from the last use. After ingestion in the form of a suspension or powder, it is recommended to rinse the mouth with a weak solution of sodium bicarbonate. If dyspepsia occurs, it should be taken after or during meals. During therapy with glutamic acid, regular general clinical urine and blood tests are necessary. If side effects develop, it is necessary to stop taking the drug and consult a doctor.

Contraindications for use

Hypersensitivity, renal or liver failure, fever, nephrotic syndrome, diseases of the hematopoietic organs, peptic ulcer, leukopenia, anemia, increased excitability, obesity, rapidly occurring psychotic reactions.

Restrictions on use

Liver and kidney diseases.

Use during pregnancy and breastfeeding

You can use glutamic acid, but only if prescribed by a doctor.

Side effects of glutamic acid

Increased excitability, abdominal pain, insomnia, vomiting, diarrhea, nausea, allergic reactions, short-term hyperthermia, chills; with prolonged use - leukopenia, anemia, cracked lips, irritation of the oral mucosa.

Interaction of glutamic acid with other substances

Together with pyridoxine and thiamine, they are used for the treatment and prevention of neurotoxic phenomena that are caused by drugs from the isonicotinic acid hydrazide group (ftivazide, isoniazid and others). At muscular dystrophy and myopathy, glutamic acid is more effective when used in conjunction with glycocol and pachycarpine.

(2 ratings, average: 5,00 out of 5)

Glutamic acid - what is it, what benefits does it bring when used by athletes in bodybuilding? Let's look at these issues in detail.

Glutamic acid is an amino acid that:

• stimulates recovery and oxidation processes in the brain;
• accelerates metabolism and the breakdown of acetone in the body;
• enhances the secretion of growth hormone;
• has a nootropic effect;
• is a source of energy for immune cells;
• used in medicine and bodybuilding.

Glutamic acid is found in whey, meat, fish, nuts, eggs, and cereals. In pharmacology it is available in the form pharmaceutical drug. The sports industry produces supplements of the same name.

What are the benefits and harms of bodybuilding?

About the benefits

Thanks to its participation in metabolic processes, the substance utilizes, binds ammonia, and promotes rapid recovery of the body after training. Glutamic acid is a building block for building muscle mass, since with its participation 25% of non-essential amino acids are synthesized.

Taking amino acids for weight enhances the quality of a bodybuilder. Supports immunity when taken anabolic steroids and intense training.

By stimulating the adrenal glands, the substance increases the body's endurance to heavy loads.

Is there any harm

There have been few studies on this topic and all of them are short-term. Therefore, we can only talk about harm tentatively.

Theoretically, taking drugs can lead to:

• pathologies of the cardiovascular system;
• diabetes and other metabolic diseases;
• neurological diseases.

All assumptions are based on the participation of glutamine in metabolism and general consequences overdose of protein in the body.

Although there are no recorded data on cases of overdose, you should not exceed the recommended dosage limits.

Dosages of the drug in bodybuilding

When athletes get into bodybuilding, they take glutamic acid in tablets from a pharmacy or in sports nutrition powder. For sports nutrition, the amino acid is produced in pure form and as part of mixtures.

Before taking medications, consultation with specialists is necessary. The norms of the drug depend on the general physical condition of the bodybuilder and the intensity of his training.

Taking the substance in its pure form

The average dose for men is 10 grams 2 times a day. First dose in the morning 30 minutes before breakfast. The second appointment is in the afternoon. On the day when there is a workout, glutamic acid is taken after visiting the gym.

Sometimes doctors advise starting to take amino acids with reduced doses, gradually increasing the amount of the drug to the recommended norms.

The drug is taken in courses of 4-6 months with a break of 2-4 months, but athletes often use it year-round. This is allowed if the bodybuilder is in general good health.

For women, a dose of 5 grams twice a day is considered sufficient.

Information on dosage varies and there are recommendations on how to drink the amino acid indicating taking 25-40 grams at a time. But these are only the opinions of individual experts.

The average athlete, of course, should adhere to generally accepted standards for taking the drug. But experienced bodybuilders sometimes increase the amount of the drug on their own, provided that they know the characteristics of their body and are confident that such a dose is harmless specifically in their case.

Taking glutamic acid as part of amino acid mixtures

When using sports supplements in the form of mixtures, the dosage of the drug remains the same. A conversion is made to the amount of mixture containing the required amount of this amino acid. Packages with complex preparations for sports nutrition always contain detailed recommendations for use.

What time of day should you take it?

Bodybuilders use several regimens for taking the drug.

1. Glutamic acid is taken in the morning 30 minutes before breakfast. The second dose is half an hour before dinner. On the day when there is a workout, glutamic acid is taken after visiting the gym.
2. Take 2-3 grams of amino acid throughout the day for maximum absorption by muscles.
3. On training days, take the drug before, immediately after, and before bedtime.

It is impossible to clearly give preference to one of the schemes; each athlete decides for himself, focusing on his well-being.

How to use glutamic acid correctly to get maximum benefits:

Firstly, glutamic acid combines well with other amino acids, so taking it in mixtures will be no less effective than in its pure form. 100% substance can be added to a ready-made protein shake.

Secondly, the substance in solution is quickly destroyed. In a cocktail useful properties won't remain. Therefore, it is better to take the mixture or drug in dry form to classes and prepare the drink immediately before use.

Glutamine and glutamic acid - what are the differences?

According to chemical reference books, these are two different amino acids, with different chemical formulas, and having identical properties.

However, glutamic acid differs from glutamine. She is a predecessor and, unlike the latter, helps eliminate.

Bodybuilders often choose glutamic acid supplements due to its detoxifying properties against lactic acid. According to bodybuilders, if the body lacks glutamine, it will synthesize the substance itself.

Contraindications and adverse reactions

Preparations containing glutamic acid are contraindicated in people with liver failure, gastric and duodenal ulcers, leukopenia, obesity, renal failure, nephrotitic syndrome, anemia, depressed hematopoietic function.

When taking the drugs, in some cases allergic reactions, dyspeptic symptoms, intestinal pain, and increased excitability are observed.

To avoid manifestation side effects It is not recommended to exceed the dosage limits for the drug.

How much does it cost and what companies produce it?

The amino acid is considered one of the most budget-friendly sports supplements. The price of the pharmaceutical drug is 28-64 rubles for 10 tablets, depending on the dosage.

The powder preparation for sports nutrition has a price tag of 130 rubles per 100 grams.

A mixture of amino acids for sports will cost significantly more. A package of 300 capsules will cost the buyer from 1,500 rubles.

There are many companies on the global market specializing in sports nutrition. The production of the above drug is carried out by the German company Wirud. Mixtures containing it - SAN, Maxler, Optimum Nutrition, NOW and others.

What analogues are there?

Among the drugs on pharmacy counters you can see packages with the names - Glutamic acid, L-glutamic acid, Epilapton, . These tools are different trade names, but have identical composition.

The sports industry also offers identical preparations with the same name and complex mixtures, which include a number of amino acids that are combined with each other.

Conclusion

In general, glutamic acid is an effective and inexpensive drug. By taking it, athletes free up the body's resources for intense training and enhance the effect of these activities. However, medical consultation is required before use.

Get better and stronger with

Read other blog articles.

Glutamic acid- a non-essential amino acid involved in the processes of transamination of amino acids in the body. The nitrogen of most amino acids goes through stages of conversion into glutamic acid, aspartic acid or alpha-alanine. Glutamic acid is involved in protein and carbohydrate metabolism, stimulates oxidative processes, promotes the neutralization and removal of ammonia from the body, and increases the body's resistance to hypoxia. Promotes the synthesis of acetylcholine and ATP, the transport of potassium ions, and plays an important role in the activity of skeletal muscles.
Glutamic acid is a neurotransmitter amino acid that stimulates the transmission of excitation at synapses in the central nervous system.

Pharmacokinetics

Indications for use

Mode of application

Side effects

Contraindications:
Contraindications for use Glutamic acid are: febrile states, increased excitability, pronounced psychotic reactions, liver and/or kidney failure, nephrotic syndrome, gastric and duodenal ulcers, diseases of the hematopoietic organs, anemia, leukopenia; childhood up to 3 years.

Interaction with other drugs

Overdose

Storage conditions

Release form

Compound:
1 tablet Glutamic acid contains L-glutamic acid 0.25 g (250 mg).
Excipients: povidone, calcium stearate, stearic acid, potato starch, sugar, light magnesium carbonate, anhydrous colloidal silicon dioxide, talc, titanium dioxide (E 171), proprietary blue V dye (E 131), yellow wax, light mineral oil.

Additionally

Main settings