Saline solution sodium chloride 0.9. Saline solution (sodium chloride) is a universal remedy. Indications for use

Or saline– a remedy that maintains blood and intercellular pressure in the body. A sodium chloride dropper is used for hypohydration and intoxication of the body, with a decrease in blood volume.

Sodium chloride - solution for intravenous administration

Composition and price of sodium chloride

Sodium chloride solution, or saline, is a colorless, salty liquid that has no distinct odor. There are 2 types of saline solution with different concentrations of NaCl: 0.9% isotonic, and 10% hypertonic.

Composition of the product per 1 liter:

There are several forms of saline solution:


Storage conditions for sodium chloride: store in a dry place, out of reach of children and pets, at a temperature of +18 to +25 degrees. The shelf life of the product is 5 years.

The cost of the solution depends on the form of release, volume and manufacturer. Average prices are:

  1. In ampoules: 30-325 rubles.
  2. In bottles and bags: 25-60 rubles.
  3. Hypertonic saline: 80-220 rubles.

The drug is dispensed from pharmacies according to the prescription of the attending physician.

How is sodium chloride beneficial for the body?

Chlorinated sodium is present in blood plasma and tissue fluids of the human body. It is responsible for the stability of the osmotic pressure of intercellular fluid and blood. When there is a shortage of this substance, water leaves the vascular bed and passes into the interstitial fluid.

This provokes the following conditions:

  • increased blood density;
  • spasms of smooth, skeletal muscles;
  • neurological pathologies;
  • disorders of the cardiovascular system.

Saline solution as a basis for injection and infusion preparations

It is incompatible or poorly compatible with the following medications:

  • norepinephrine;
  • corticosteroids;
  • leukopoiesis stimulator Filgrastim;
  • antibiotic Polymyxin B.

At arterial hypertension Sodium chloride should not be combined with Enapril and Spirapril: the use of saline solution reduces the hypotensive effect of these drugs.

The saline solution has an osmotic pressure similar to the human blood environment, and therefore is quickly eliminated from the body. Already 1 hour after using the dropper, less than half of the product remains in the body.

Why is saline solution prescribed?

Saline solution is administered intravenously in the form of infusions when indicated:

  1. Severe and critical dehydration of the body, disturbance of water-salt balance.
  2. Reduced plasma volume with large blood losses, dyspepsia, severe burns, diabetic coma.
  3. Carrying out surgical procedures, postoperative period.
  4. Intoxication of the body due to infections and poisonings of various origins.
  5. Epigastric, ileocecal, pulmonary bleeding.
  6. Digestive pathologies: nausea, vomiting, diarrhea, chronic and acute constipation.
  7. Lack of Na and Cl in the body.

When introducing droppers of saline solution with additional components, the list of indications expands.

Instructions for use for dropper

Before introducing sodium chloride inside, it must be heated to a temperature of 36-38 degrees. The dosage of the drug is calculated individually, based on the patient’s condition, medical history, age and weight.

The average daily dosage of the drug varies in the following values:

  1. Adults: 500-3000 ml.
  2. During pregnancy: 300-1200 ml.
  3. Children: 20-100 ml per kg of weight.

To instantly replenish the lack of Na and Cl, 100 ml is administered once.

The average dropper speed is 540 ml/h. Hypertonic solution injected in a stream.

Jet injection of saline solution

For dilution and drip administration of other drugs, from 50 to 250 ml of physiological solution per dose of the drug is used.

Side effects

Rare negative effects that occur with prolonged or heavy use of sodium chloride include:


If such complications occur, the administration of saline solution is stopped, and the patient is given assistance to eliminate the side effects.

Contraindications for intravenous administration

Infusion of saline solution is prohibited for the following pathologies:


IV with saline solution– a quick and effective way to replenish blood volume in the body, restore water-salt balance, and cleanse toxins. To prevent the product from causing a negative reaction, it should be used exclusively under the supervision of a physician.

Modern pharmacology has long and actively used in a variety of medical purposes sodium chloride. This substance is better known to ordinary people as “saline solution”. It is used both intravenously and intramuscularly.

Why do they put sodium chloride on a drip? In what situations does this compound help? When does saline become the most relevant medicine? Let's talk about this.

Sodium chloride - universal remedy, widely used in medicine

The composition of human blood includes many different chemical bioactive compounds. For everyone's safe work internal systems and organs of the body, the concentration of chlorides in the blood plays an important role.

Composition of physiological fluid

Chlorides maintain and regulate the normal hydrobalance of body fluids and plasma, stabilize acid-base metabolism. A healthy level of intracellular pressure depends on the indicators of chloride inclusions.

When on human body Various pathological problems occur and he begins to suffer from dehydration. Pathologies are the main culprits of increased leaching of calcium and chlorine ions from blood cells. The body reacts to a drop in their normal concentration and a growing deficiency of beneficial microelements in the following way:

  • the functioning of the central nervous system is disrupted;
  • the blood begins to thicken;
  • muscle tissue spasms;
  • the functionality of cardiovascular activity decreases.

This is where saline solution comes to the rescue. Sodium chloride is a plasma-substituting substance with a salty taste (in everyday life it is known as a solution of ordinary table salt). It is prepared using sodium salts of hydrochloric acid. A solution with hydrating properties is successfully used to restore the normal water balance of the body.

Where else is sodium used? modern medicine

Chlorine promotes effective disinfection of various liquids, but in pure form This chemical compound poisonous. But chlorine in combination with sodium is a quite useful substance. This combination is present in the natural fluid tissues of the body and blood plasma.

Sodium chloride enters the human body regularly through food and water. This inorganic component is extremely important for the normal functioning of all internal systems.

In what form is sodium chloride used?

More often, saline liquid is used as a solution for intravenous infusion. But this is far from the only use of the compound for medical purposes. Sodium chloride is used as:

  • liquid for treating and disinfecting wounds and cuts;
  • antiseptic solution for gargling and nasal rinsing;
  • for diluting various drugs used for injection (intravenous and intramuscular).

What does sodium chloride solution consist of?

Modern pharmaceuticals produce a physiological solution with therapeutic effects in varying degrees of concentration. At the moment it is produced in two types:

Isotonic solution Brown (0.9%). German manufacturers are engaged in the production of this substance. The solution is intended for:

  1. Restoring significant loss of intracellular plasma due to prolonged dyspepsia. Dyspepsia is a serious disorder of the digestive processes.
  2. Replenishment of intercellular fluid due to dehydration resulting from prolonged vomiting and diarrhea.
  3. Replenishment of necessary ions when different types intoxications (poisonings) and as a result intestinal obstruction.
  4. As an external wash for wounds and burns.
  5. For diluting essential medications produced in concentrated form.

Hypertonic solution (3, 5 and 10%). Physiological fluid of this type is used in the following cases:

  1. How external antiseptic for washing purulent wounds.
  2. When diluting enema solutions to cleanse the intestines.
  3. Intravenous infusion to relieve diuresis (increased urination). This is observed in severe poisoning.
  4. Drip infusion to relieve cerebral edema, increase low pressure(especially when internal bleeding).
  5. As a local anti-edema agent in ophthalmology.

Chlorine is a vital element, indispensable for replenishing lost microelements. Together with sodium and potassium, this compound maintains the normal balance of body fluids.

When intravenous infusion of sodium chloride, the ampoule of the substance must be heated to a temperature of +38⁰ C. Depending on the specifics of use, different dosages of the product are used.

Why is sodium chloride given intravenously?

Physiological saline liquid as an inert drug is the most universal remedy of modern medicine. Sodium chloride droppers are included in almost every complex therapy. As an intravenous infusion, this agent is used for:

  1. Accelerated replenishment of lost blood volume.
  2. Restoring normal microcirculation internal organs, observed at in a state of shock person.
  3. Complete saturation of the body with vital ions.
  4. Relief of intoxication processes that occur during poisoning of any kind and type.

But the most common use for which a sodium chloride dropper is used constantly and daily is to relieve symptoms of poisoning. This type of therapy is especially relevant when the harm from toxic substances is very high.

What is saline solution used for?

Saline and pregnancy

Thanks to its unique and universal composition, sodium chloride can also be used in the treatment of pregnant women. Due to its identity with the natural composition of blood, such a substance does not harm the developing fetus and the body of the expectant mother at all.

How exactly is the dropper used, and why is NaCl used in the case of pregnant women? More often this drug is diluted medicines, intended for a single infusion of a dose of up to 400 ml.

In cases where it is necessary to restore the natural blood level, the dose of saline solution is increased to 1,400 ml.

Sodium chloride solution is also used in the following cases:

  • with severe toxicosis;
  • to relieve severe swelling;
  • when carrying out detoxification methods;
  • during complicated childbirth taking place at low blood pressure;
  • to saturate internal organs with the necessary chlorides and vitamins;
  • at caesarean section, which is necessary for women suffering from arterial hypotension.

Drip administration of plasma replacement fluid is also permitted during the lactation period. Such therapy is carried out only as prescribed by a doctor and after all tests have been performed. Preliminary research is necessary, because for all its harmlessness, sodium chloride solution also has contraindications. It should not be used if a pregnant woman:

  • when observing excessive hyperhydration;
  • in case of observed heart failure;
  • if a woman has to take corticosteroids;
  • in case of severe disturbances in the circulation of intracellular fluid;
  • A deficiency of potassium in the body with a simultaneous excess of sodium and chlorine was diagnosed.

Droppers for alcohol intoxication

Poisoning ethyl alcohol each person is expressed and proceeds individually. For some, this is a state of mild malaise, while others require specialized assistance doctors Doctors are required to include drips with saline in therapeutic measures.

Droppers in this case become the most in effective ways relieving symptoms of alcohol withdrawal. Various other suspensions, tablets and mixtures become ineffective for the following reasons:

  1. The main symptom of this condition is vomiting. Sometimes it can be so strong that a person is unable to take the pill. Drugs taken orally become ineffective, unlike droppers.
  2. Thanks to intravenous infusion, the necessary medicine instantly enters the bloodstream, which makes the therapeutic measures more successful.
  3. The use of saline is unique. With its help, you can dilute and introduce into the body several necessary substances at once. medical supplies: sedatives, vitamins, saline solutions, glucose, etc.

Initially, the doctor examines the patient and assesses the severity of his condition. Based on the data obtained after an ECG, blood pressure and pulse measurements, doctors prescribe drugs that will be added to the physiological fluid.

Drip infusion when returning a person to life in case of alcohol intoxication is carried out within 3-4 days. Thanks to the creation of this unique substance - sodium chloride, doctors were able to save many frivolous lives affected by overuse alcohol.

In contact with

Sodium chloride is a drug that has long been used in medicine. This saline solution is administered intravenously in the form of droppers and intramuscularly, used for inhalation, etc.

In medicine, sodium chloride is used:

  • For intravenous infusion as a sodium solution in the form of a dropper.
  • For diluting drugs for injection.
  • For disinfecting cuts and wounds.
  • For rinsing the nose.

Why droppers with sodium chloride are prescribed and for what conditions it is prescribed is described in detail below.

What it is?

  • There are many chemical bioactive compounds dissolved in human blood.
  • The concentration of chlorides in the blood plays a big role in the coordinated functioning of all internal systems.
  • Chlorides regulate the hydrobalance of plasma and body fluids, normalize acid-base metabolism.
  • When the body gets sick, the first thing it reacts to is dehydration.

With extensive dehydration, chlorine and potassium ions are washed out of the body. A decrease in their concentration causes blood thickening, spasms, convulsions of smooth muscles, as well as disruption of the central nervous system, heart and blood vessels.

In this case, a drip with saline sodium chloride solution is usually prescribed.

What does the dropper consist of?

The composition of the saline solution is sodium chloride - a plasma-substituting substance, which is prepared from sodium salts HCl (commonly known as table salt).

Sodium chloride (NaCl) is white crystals, readily soluble in water.


Chlorine in its pure form is poisonous, but is known as an effective disinfectant of various liquids. Chlorine combined with sodium is present in the blood plasma.

The substance enters the body with water and food.

Naturally, the use of sodium chloride in everyday life is limited primarily to cooking.

Therefore, if you drink sodium chloride solution, nothing will happen. There is no need to worry even if the child drank the solution due to the negligence of adults.

Properties of sodium chloride

Sodium chloride saline solution has a rehydrating effect - that is, restoring water balance.


0.9% sodium chloride has the same osmotic pressure as human blood, so it can be quickly excreted.

External use helps remove pus from the wound and eliminate pathological m microflora.

The use of saline solution through intravenous drips increases urine output and replenishes the lack of chlorine and sodium.

Types of saline solution

Saline solution sodium chloride for droppers is currently available in 2 types, differing in the degree of concentration.

Photos (clickable):

Isotonic physiological Nacl 0.9% solution Brown from a German manufacturer is prescribed for:

  • Restoration of intracellular plasma lost as a result of prolonged dyspepsia.
  • Replenishment of intercellular fluid lost as a result of dehydration.
  • Replenishment of ions during intoxication and intestinal obstruction.
  • As an external remedy.
  • For diluting concentrated drugs.

Hypertonic 3, 5 and 10% sodium chloride solution is used:

  • As an external antiseptic.
  • For diluting enema solutions.
  • Intravenous to replenish fluid during diuresis.
  • Infusion to relieve cerebral edema or to increase low blood pressure (particularly with internal bleeding).
  • As an anti-edematous agent in ophthalmology.


Sodium chloride solution is sold in ampoules for dissolving drugs for injection and in bottles with a capacity of up to 1 liter for external and enema use, intravenous infusion.

Oral tablets and nasal spray bottles are also produced.

Release form, composition and packaging

Solution for injection 0.9% - 100 ml, sodium chloride 900 mg

  • 1 ml - ampoules (10) - cardboard packs.
  • 2 ml - ampoules (10) - cardboard packs.
  • 5 ml - ampoules (10) - cardboard packs.
  • 10 ml - ampoules (10) - cardboard packs.

What is sodium chloride prescribed for?

Saline sodium chloride solution is perhaps the most universal remedy.

Droppers with sodium chloride are used in any complex therapy.

The drug is dripped intravenously for:

  • Rapid replenishment of blood volume.
  • Urgent restoration of the activity of internal organs in a state of shock.
  • Saturation of organs with vital ions.
  • Stopping the processes of intoxication and relieving symptoms of poisoning.

In these conditions, urgent use of sodium chloride in droppers is most often prescribed:

  • Diarrhea.
  • Vomiting.
  • Dyspepsia.
  • In the presence of extensive burns.
  • With cholera.
  • When the body is dehydrated.

During pregnancy

Sodium chloride is used to treat severe pathologies in pregnant women.

The saline solution is absolutely harmless to both the woman’s body and the developing fetus.

Typically, sodium chlorine is needed during therapy for pregnant women; it is needed for dilution medicines for a single infusion up to 400 ml.

If it is necessary to restore blood levels, the amount of saline is increased to 1400 ml.

Sodium chloride is also used for pregnant women:

  • In case of severe toxicosis, the saline solution is additionally saturated with vitamins.
  • With gestosis.
  • During detoxification.
  • In the process of complicated childbirth occurring at low blood pressure.
  • During cesarean section for women suffering from hypotension.
  • To saturate organs with chlorides and vitamins.

The use of saline solution after childbirth during lactation is allowed.

Sodium chloride solution also has contraindications during pregnancy. It should not be used by a pregnant woman:

  • With excessive hyperhydration.
  • With heart failure.
  • During treatment with corticosteroids.
  • With pathologies of intracellular fluid circulation.
  • With a diagnosed lack of potassium with a simultaneous excess of sodium and chlorine in the body.

For alcohol intoxication

In case of severe poisoning with ethyl alcohol, a person requires qualified health care, which includes therapeutic measures, as well as droppers with saline sodium chloride solution.


It is the droppers that relieve the symptoms of alcohol withdrawal.

Other drugs, such as tablets or suspensions, are usually ineffective, since they are difficult to take due to frequent vomiting.

And the medicine, poured into a vein through a dropper, enters the blood instantly and immediately begins to work.

NaCl combines well with many medications.

Saline solution sodium chloride can be diluted simultaneously with several necessary medications: vitamins, sedatives, glucose, etc.

When diluting, it is imperative to check compatibility visually, paying attention to whether a precipitate has appeared during the mixing process or whether the color has changed.

Therapy for severe alcohol intoxication is carried out as follows:

  1. The doctor examines the patient, assessing the severity of his condition.
  2. Blood pressure and pulse are measured and an ECG is performed.
  3. The doctor prescribes medications that must be added to the saline solution for administration.
  4. Droppers are used for 3-4 days.

How is saline solution administered?

Isotonic sodium chloride solution can be administered intravenously and subcutaneously.

For intravenous administration the dropper warms up to 36-38 degrees.

The volume that should be administered depends on the amount of fluid lost by the body. The person’s weight and age must be taken into account:

  • Average daily dose– 500 ml, which must be administered at a rate of 540 ml/hour. In case of severe intoxication, the volume of administered medication per day can reach 3000 ml.
  • A volume of 500 ml in emergency cases can be administered at a rate of 70 drops per minute.

Sodium chloride is used in compliance with the principles of sterility.

To prevent air from entering the drip system, the system is first filled with solution.


You cannot stack containers one after the other, as air may get in from the first package.

Medications can be added during an infusion or by injection into the specific area of ​​the package intended for this procedure.

During the administration of sodium chloride, it is necessary to monitor the patient’s well-being, it is necessary to monitor his biological and clinical indicators, and devote time to assessing plasma electrolytes.

Side effects

The drug is well tolerated by patients, but with its excessive infusion the following may develop: side effects:

  • Acidosis.
  • Hypokalemia.
  • Overhydration.

Sodium chloride analogues

Manufacturers may market sodium chloride solution under different names.

The following analogues of saline solution can be found on sale:

  • Aqua-rinosol - spray.
  • Aqua-master - spray for irrigation.
  • Nazol - spray.
  • Bufus for injections.
  • Rizosin to moisturize the nasal mucosa.
  • Salin to moisturize the nasal passages.

Other isotonic preparations are also produced that have a more physiological composition than saline.

List of solutions for droppers,containing sodium chloride in the composition:

  • Ringer.
  • Ringer-Locke.
  • Krebs-Ringer.
  • Ringer-Tirode.
  • Disol, Trisol, Acesol, Chlosol.
  • Sterofundin isotonic.

The saline solution of the medicine must be administered subcutaneously or intravenously.

Patients are usually prescribed an intravenous drip. Before the procedure, the dropper with the medicinal solution must be heated to a temperature of 36-38 degrees. The volume of solution administered to a person depends on his condition, and at the same time on the amount of fluid lost by the body. In addition, when selecting a dose, it is necessary to take into account the patient’s weight and age.

On average, 500 ml is allowed per day medicinal substance. The average rate of administration is 540 ml/hour. In case of severe poisoning, the volume of the administered drug can reach up to 3000 ml. If necessary, injections of 500 ml of solution are allowed, which are administered at a rate of 70 drops/minute.

Children's daily portions are 20-100 ml/kg. The dosage size depends on the age and weight of the child. It is necessary to take into account that in case of long-term use of the solution, it will be necessary to monitor the electrolytes in the urine with plasma.

To dilute medications administered to patients through a dropper, it is necessary to use 50-250 ml of the drug per 1 serving of such a drug. The characteristics of the injection in these cases are determined by the drug that is dissolved.

Solution hypertensive type required to be administered intravenously using the jet method.

In the case of using drugs to quickly replenish the lack of NaCl ions, it is necessary to administer the drug by drop method (in a dose of 100 ml).

To perform a rectal enema that causes bowel movement, you need to administer a 5% solution of the drug (dose 100 ml). In addition, 3000 ml of saline solution of the drug can be administered throughout the day.

Hypertensive enemas should be used slowly for the following disorders: increased ICP, swelling in the heart or kidneys, and hypertension. The size of the administered dose is within 10-30 ml. It is forbidden to perform such an enema if the patient has inflammation or erosion inside the large intestine.

Purulent wounds should be washed in accordance with the regimen prescribed by the doctor. Compresses soaked in the solution must be applied directly to the area with damage or wound. Such compresses help remove pus and destroy pathogenic microbes.

The spray must be instilled into the nose after cleaning it first. The dose for adults is 2 drops in each nostril, and for a child – 1 drop. The spray can be used both for therapy and as prophylaxis (in this case, the solution must be instilled for approximately 20 days).

In the form of inhalations, the drug is used to relieve colds. In such cases, the solution should be mixed with bronchodilator medications. Inhalations should be performed 3 times a day, each procedure for 10 minutes.

If this is absolutely necessary, you can make your own saline solution. In this case, you need to dissolve 1 teaspoon of ordinary salt in 1 liter of boiled water. If it is necessary to produce a certain amount of liquid (for example, a portion of salt is 50 g), it is necessary to carry out all the necessary measurements. This solution can be used topically, for inhalation with rinsing, and also for enemas. But under no circumstances is it allowed to use a self-prepared solution for intravenous injections or treatment of eyes or open wounds.

Saline solution or sodium chloride is quite widely and actively used in modern medicine. It is noteworthy that it has been helping people out for decades and continues to be relevant; it has no competitive substitutes. Saline solution can be taken intravenously and intramuscularly, as a means for washing the nose, gargling, and for treating wounds. In other words, its range of applications is large.

Indications for the use of sodium chloride for the treatment of diseases

So, why do they put in a sodium chloride drip? First of all, to regulate the well-being and condition of the body during dehydration, a sodium chloride dropper is capable of restoring the body’s water balance in a fairly short time, due to which the sodium deficiency is quickly replenished, which, of course, has a beneficial effect on the patient’s condition and well-being. It is very important that the solution does not linger in the body, it is quickly eliminated.

If intoxication of the body occurs, for example, with dysentery and food poisoning, a sodium chloride drip is also given, because the solution helps remove accumulated toxins. By the way, within an hour after the administration of saline solution, a patient with poisoning will feel much better, and after a few hours, a sodium chloride dropper, if indicated, can be placed again, but, as a rule, one is enough.

Also, saline solution is used to rinse the nose, which is very good for a runny nose. The solution is able to wash away all pathogenic infections and moisturize the mucous membrane. By the way, you can use saline solution to rinse the nose for small children, even newborns, who cannot ease their breathing with drops or sprays.

Why is a sodium chloride drip placed in ENT practice? To rinse the nose, but not externally, as described above, but internally, that is, a sodium chloride dropper is placed directly into the nasal sinuses. This is most often done for acute purulent sinusitis.

The throat can also be washed, this is especially true for influenza, acute respiratory infections or sore throat. At the same time, in the presence of purulent deposits, you need to gargle with saline solution as often as possible.


During pregnancy, women often have health problems, so a sodium chloride dropper can also be given, but in this case the solution should be administered only as prescribed by a doctor. You cannot do this on your own!

It is very important to note that during pregnancy, more than 400 ml of saline solution should not be used in one infusion; this is quite enough to maintain a normal state. An increase in the volume for administration can only be prescribed by a doctor based on diagnostic results.

The composition of the sodium chloride dropper is very similar to the composition of blood and therefore it can be given even to pregnant women and small children. Saline solution - universal medical product, time-tested.