Relium how to take. Application of Relium in neurological practice: instructions and reviews. Directions for use and dosage

Reasons for taking Relium tablets:

Relium was prescribed by a doctor for very severe stress, which led to emotional imbalance (hysterics, sudden changes in mood, sleep disturbance and lack of sleep at all). Due to the strong emotional tension and stress that I experienced, it was very difficult to fall asleep and my sleep was disturbing. Sometimes I couldn’t fall asleep all night, sometimes I could wake up at 3-4 in the morning and could not fall asleep again and had constant anxious thoughts. The stress was caused by the death of a loved one; she could not cope without medication.

Instructions for use:

Adults for neuroses, neurasthenia, hysteria, spastic paralysis, prevention of epileptic seizures: 2-10 mg 3-4 times a day. Withdrawal syndrome in patients with alcoholism: 10 mg 3-4 times on the first day, followed by a daily dose reduction of 5 mg 3-4 times a day. In elderly patients, a single dose is 1-2.5 mg 3-4 times a day. If necessary, the dose is gradually increased. For children, the dosage is prescribed individually depending on age and disease.

The dosage prescribed by the doctor was 2 tablets per day, at the end of the course I switched to half a tablet. The tablet is very small, but it was possible to break it. Taken at lunch and before bed. I washed it down with water (half a glass).

Indications for use:

Neuroses, neurasthenia, hysteria, reactive depression, agoraphobia, insomnia associated with a violation of the phase of falling asleep, Meniere's disease, spastic paralysis, withdrawal syndrome in patients with alcoholism, status epilepticus, epilepsy, premedication before surgical interventions and endoscopic manipulations; LSD poisoning.

Relium analogues:

The active ingredient in Relium is diazepam. Although Relium is an imported drug, its price is humane (from 30 to 50 rubles). This is the lowest price among Relium's analogues. Here are some of them:

• Relanium (price about 100 rubles), also made in Poland. Relanium prescription drug, you won’t be able to buy Relium without a prescription.
• Sibazon (price about 30 rubles), Russian production. Sold by prescription.
• Also analogues of Relium are tablets and injection solutions Seduxen and Apaurin.

Once again I want to repeat that the drugs are strong, so they are all sold strictly according to a doctor’s prescription. This strict application is due not only to the large list side effects, but also because it is addictive.

Contraindications:

Increased sensitivity acute diseases liver and kidneys with impaired function, myasthenia gravis, angle-closure glaucoma, first trimester of pregnancy, breastfeeding.

Side effect:

Habituation, paradoxical reactions (development of anxiety, hallucinations, convulsions, insomnia), decreased reaction speed and concentration, drowsiness, deterioration of short-term memory, ataxia, dysarthria, headache, dizziness, hypotension, bradycardia, with prolonged use, liver and kidney damage, intestinal atony, decreased libido and potency, reactions at the injection site, withdrawal syndrome, aftereffect syndrome (decreased performance, muscle weakness), allergic reactions.

I didn’t read reviews on Relium before using it, I didn’t have time for that, I trusted the doctor and didn’t regret it. I had no side effects.

Pros:

1. Efficiency. After taking Relium tablets, the effect occurred after about 1.5-2 hours. There was a feeling of calm, anxiety and nervous tension passed.
2. Healthy and sound sleep. As I wrote above, I took the pill before bed. After this, there were no problems falling asleep, the sleep was sound and without waking up in the middle of the night. In the morning there was no feeling of sleepiness. But after taking the next pill in the afternoon (after lunch), drowsiness began again, but at the same time a feeling of calm and even a slight increase in mood.
3. A cheap medicine that is affordable for everyone (30-50 rubles).

Minuses:

1. There are a huge number of side effects and it is not known whether any of them will work or can be avoided. Luckily, I didn’t experience any side effects.
2. Very strong drug, which may be addictive. I moved away from it gradually, reducing the dosage. First, I reduced it from 2 tablets a day to 1 tablet, then only half at night. Therefore, there was no withdrawal effect.

What helped me get out of depression? Drug treatment(relium and grandaxin), family support, bicycle and spring.

Result: positive feedback

An excellent remedy for neuroses and depression

Advantages: Helps quickly and effectively

Disadvantages: Difficult to buy, requires a prescription

It puts the brain back in place well, it’s inexpensive, but the main problem here is that not everyone agrees to get the doctor to prescribe it. And the medicine is very good. It was prescribed to me for depression and it helped me a lot. The “flies” stopped flying in front of my eyes, I slept well, the neighbors didn’t bother me, although I usually listen, and just then it starts to irritate me, after which I can’t sleep anymore. There are no side effects, it’s just an ideal cure for psychosis, neuroses and other things. Anxiety is removed 100%. After the course, the effect was enough for me for about six months, then the doctor did not want to prescribe it, he said there would be an addiction, after that I took other medications, but they are no longer so effective.

Result: positive feedback

Helped with insomnia

Advantages: The drug helped

Disadvantages: There were no side effects

After I suffered a head injury from a fall, I developed anxiety and insomnia. Help yourself with traditional medicine I couldn't and had to see a doctor. Sometimes I wake up in the middle of the night and can’t sleep until the morning, then you walk around all day as if exhausted, and fatigue accumulates. Periodically there are muscle cramps. The doctor prescribed me the drug Relium. We scheduled the first course for four weeks and from about the second week I already felt relief, I was able to at least sleep until the morning. After the break, I took the second course of Relium. At the moment I am generally satisfied with my condition.

Result: positive feedback

Helped cope with insomnia

Benefits: Efficiency

Disadvantages: none found

There was a difficult period in my life, which Relium helped me cope with. First, I had problems at work, and then a divorce - all these are extremely stressful situations that cannot pass without leaving a trace on a person’s psyche. I stopped sleeping completely, I just couldn’t sleep normally for 3 days, I fell asleep on the 4th, and then everything started again. I had to go to a neurologist, he advised me to take Relium - as a mild sleeping pill and sedative. You need to take 1 tablet before bedtime. After 2 weeks of taking it, my psychological state improved, and as a result, insomnia went away. Relium did its job perfectly, and most importantly, it did not cause any side effects on health.

Result: positive feedback

Mild tranquilizer, helped to fall asleep, but not lethargic in the morning

Benefits: restores sleep, normal sleep

Disadvantages: sleepy in the morning, relaxed

I admit, I relieve stress with good weak alcohol - wine, tinctures... But in Last year I was wildly exhausted at work, so I couldn’t sleep, I couldn’t fall asleep until 4-5 in the morning, and herbal sedatives like valerian tincture didn’t help, and I couldn’t sleep with glycine either. Finally, I went to see a doctor to help restore my daily routine. The neurologist spent a long time naming drugs that could help me, settled on the name - Relium, and prescribed me to take it as a joke before bed for severe insomnia and feelings of anxiety, when some kind of unhealthy internal dialogue is being conducted. Sleep really improves with it - I took about two-thirds of the pack (of 20 tablets) over the course of a month. But in the morning there is a certain feeling of drowsiness, which takes longer than usual, by the way, there is an impressive list side effects... Still, I’m glad that my sleep has been restored, I hope to do without sleeping pills and tranquilizers in the future.

Result: positive feedback

Mild sleeping pill

Advantages: effective, inexpensive, non-addictive

film-coated tablets 5 mg

Registration number:

P No. 015047/02-2003

Tradename

RELIUM

International nonproprietary name

Diazepam

Dosage form, dose

film-coated tablets, 5 mg

Compound:

active substance:
diazepam 5 mg

Excipients:
potato starch, gelatin, Tween 80, talc, quinoline yellow magnesium stearate E 104, lactose

shell composition:
cellulose acetate phthalate, polyethylene glycol 6000

Description

Film-coated tablets, round, convex on both sides, without frayed edges or cracks, yellow in color. Yellow at the break.

Pharmacological group:

Group affiliation according to the ATS classification: N 03 AE, N 05 BA.
Anxiolytic drug from the group of benzodiazepines

PHARMACOLOGICAL PROPERTIES

Pharmacodynamics

Diazepam belongs to the group of benzodiazepine derivatives.

The drug acts on many structures of the central nervous system. The mechanism of action of the drug is closely related to the inhibitory endogenous neurotransmitter gamma-aminobutyric acid (GABA) and the GABA-A receptor, through which the neurotransmitter realizes its effects in the central nervous system.

Like all other benzodiazepines, diazepam enhances the inhibitory effect of GABAergic neurons in the central nervous system.

The clinical effect of diazepam is manifested by a pronounced anxiolytic and anticonvulsant effect; The hypnotic and central muscle relaxant effect is somewhat less pronounced.

Pharmacokinetics

Suction

After oral administration diazepam is well and quickly absorbed from the digestive tract, bioavailability is 98%.

After oral administration of one dose of the drug 20 mg, the maximum concentration of the drug in the blood serum (Cmax) is reached after 50-90 minutes and is approximately 500 ng/ml.

Distribution

Diazepam is approximately 94-99% bound to blood proteins. The drug passes through the blood-brain and placental barrier and penetrates into mother's milk. Shows great affinity for adipose tissue, in which it is deposited and from there gradually released into the blood.

The volume of distribution is 1.1-1.5 l/kg.

Metabolism

Diazepam is extensively metabolized in the liver to the active metabolites N-desmethyldiazepam (nordazepam) and N-methyloxazepam. Both metabolites undergo conversion to the pharmacologically active oxazepam, which binds to glucuronic acid.

The half-life (t 1/2) is 24-48 hours; may be prolonged in newborns and elderly patients (active metabolites prolong the half-life; the half-life of N-desmethyloxazepam can reach up to 100 hours, depending on age and liver activity).

Selection

The drug is excreted mainly in the urine in the form of metabolites; up to 25% of the drug can be excreted unchanged by the kidneys. Repeated doses of the drug may lead to accumulation of the drug and its metabolites.

INDICATIONS FOR USE

• neuroses, borderline states with symptoms of tension, anxiety, anxiety, fear
• for alcohol withdrawal syndrome, in order to reduce symptoms of agitation
• in complex therapy for diseases associated with increased skeletal muscle tone (after injuries, spastic conditions after cerebral strokes)
• sleep disorders
• in complex therapy of epilepsy (in combination with other anticonvulsants)
• motor agitation of various etiologies
• in preparation for surgical interventions and diagnostic procedures

The drug should be used strictly as prescribed by the doctor to avoid complications.

METHOD OF APPLICATION AND DOSES

The dosage and duration of treatment should be selected individually for each patient in order to obtain maximum treatment effects.

The following doses are usually used:

Adults

Conditions of fear: 2-10 mg 2-4 times a day.

Alcohol withdrawal syndrome: 10 mg 3-4 times a day during the first 24 hours, then (if necessary) 5 mg 3-4 times a day.

Diseases accompanied by increased skeletal muscle tone: 2-10 mg 3-4 times a day.

Sleep disorders: 5-15 mg in a single dose before bedtime.

Epilepsy (in combination with other drugs): 2-10 mg 2-4 times a day.

Preparation for surgical interventions and diagnostic procedures: 5-20 mg in a single dose or in divided doses before surgery.

Maximum daily dose: up to 60 mg/day (in complex therapy of epilepsy, often in spastic conditions)

0.1-0.8 mg per 1 kg of child’s body weight per day.

From 1 year to 3 years: 1-1.5 mg – 2-3 times a day. Daily dose 2.5 – 5.0 mg.

3 – 7 years: 1.5-2.5 mg - 2-3 times a day. The daily dose is 5-7 mg.

The drug should not be used in children under 1 year of age.

Elderly patients (over 65 years old)

Diazepam should be used with caution in elderly patients. A dose reduction is recommended. Usually 2 – 2.5 mg 1 – 2 times a day. If necessary, the dose can be gradually increased (provided the drug is well tolerated).

Patients with impaired liver and kidney function.

The duration of therapy is usually 4 weeks (including the time of gradual reduction of the drug dose). Do not take the drug for more than 4 weeks without re-evaluating the need to continue therapy.

You cannot abruptly discontinue the drug; a gradual, doctor-controlled, dose reduction is always necessary. Abrupt withdrawal of diazepam can lead to sleep and mood disorders, and even mental disorders. Abrupt withdrawal during long-term therapy or when using large doses of the drug is especially dangerous. Withdrawal symptoms are then more pronounced.

SIDE EFFECT

The most common undesirable effects during drug therapy are: drowsiness, tiredness, tiredness, impaired coordination of movements.

Less common: dizziness and headache, disorders of the digestive tract (nausea, constipation), blurred vision, slurred speech, liquefaction of blood pressure, depression, states of disorientation, decreased libido, skin allergic reactions, urination disorders, neutropenia, yellowness of the skin (during long-term therapy, periodic monitoring of blood patterns and liver function tests is indicated), paradoxical reactions (states of psychomotor agitation, insomnia, fear).

If paradoxical reactions occur, treatment should be interrupted immediately.

Systematic use of the drug for more than 2-3 weeks can lead to the development of drug dependence, as well as withdrawal syndrome in case of abrupt withdrawal.

Warnings

Long-term use of diazepam leads to a gradual weakening of the effect of the drug as a result of the development of the phenomenon of tolerance.

Long-term use of the drug contributes to the development of psychophysical drug dependence and withdrawal syndrome in case of abrupt withdrawal of diazepam. Withdrawal syndrome is characterized by psychomotor agitation, fear, autonomic disorders and insomnia.

During treatment with diazepam and for 3 days after its completion, you should not drink any alcoholic beverages.

CONTRAINDICATIONS

• hypersensitivity to benzodiazepines,
• breathing disorders of central origin and severe conditions of respiratory failure, regardless of the cause,
• myasthenia gravis,
• angle-closure glaucoma,
• disturbances of consciousness.

Do not use in children under 1 year of age.

USE IN PREGNANCY AND BREAST-FEEDING

The use of a medicine during pregnancy is allowed only if its use by the mother has absolute indications, and the use of a safer, alternative remedy is impossible or contraindicated. During treatment with diazepam, you should not breastfeed.

INTERACTIONS WITH OTHER MEDICINES

Pharmaceutical

Pharmaceutical types of incompatibility are not defined

Pharmacodynamic

The inhibitory effect of diazepam on the central nervous system is enhanced by all drugs with a similar effect: sleeping pills(eg barbiturates), drugs that lower arterial pressure central action, antipsychotics, antidepressants, anticonvulsants, narcotic analgesics.

Shows a similar effect ethanol. Drinking alcohol during treatment with diazepam, in addition to its cumulative depressant effect on the central nervous system, can provoke paradoxical reactions: psychomotor agitation, aggressive behavior.

The drug enhances the effect of drugs that reduce skeletal muscle tone.

Pharmacokinetic

Oral contraceptives may slow down the metabolism of diazepam and enhance its effect.

Smoking may reduce the effect of diazepam.

OVERDOSE

As a result of an overdose of diazepam, the following symptoms may appear: drowsiness, disorientation, slurred speech, and in severe cases, loss of consciousness and coma.

At acute poisoning it is necessary to induce vomiting and rinse the stomach.

Treatment for diazepam overdose is primarily symptomatic and consists of monitoring vital signs (respiration, pulse, blood pressure).

A specific antidote is flumazenil (a benzodiazepine receptor antagonist).

SPECIAL INSTRUCTIONS

Impact on the ability to drive vehicles and maintain moving mechanical devices

During treatment with the drug and for 3 days after its completion, you should not drive a vehicle, service moving mechanical devices, or perform work that requires special attention and quick response.

RELEASE FORM

Film-coated tablets 5 mg

Package

20 tablets per blister.
One blister along with instructions for use is placed in a cardboard box.

STORAGE CONDITIONS

Store at temperatures up to 25°C. Protect from light and moisture.
List of potent and toxic substances No. I on PKKN
Keep out of the reach of children.

BEST BEFORE DATE

3 years
Before using the drug, you must check the expiration date indicated on the packaging.
The drug should not be used after the date indicated on the package.

CONDITIONS FOR DISCHARGE FROM PHARMACIES:

according to a doctor's prescription.

MANUFACTURER

Tarkhoma Pharmaceutical Plant "Polfa" Joint Stock Company

st. A. Fleming 2

Currently, the issue of treating psychiatric and neurological diseases associated with the functioning of the GABAergic system is very urgent. This is due to the fact that these conditions occupy a large percentage of the overall morbidity structure. They dramatically disrupt a person’s labor, social and everyday life. In this regard, many drugs are released onto the market every year that have the ability to normalize the activity of mediators and receptors nerve tissue. One of these medications is Relium, which, according to the instructions for use, has wide range actions and can be used in children, but is not completely safe.

General information about the drug Relium

Relium is a standard psycholeptic of European quality. It is produced in Warsaw (Poland) at the Polfa pharmaceutical concern. The medication has a combined effect, providing anticonvulsant and sedative effects. The drug is included in the list of recommended products. medical institutions, compiled World Organization healthcare.

Drug group, INN, scope of application

Relium refers to pharmacological group psycholeptic drugs, a subgroup of anxiolytics, benzodiazepine derivatives. A special feature of this group is that all drugs included in its composition are sold strictly according to prescription. International generic name(INN) - Diazepam.

The drug is actively used in psychiatric, neurological and drug addiction practices. It can also be used in selected clinical cases of infectious diseases.

Release forms

Available in the form of film-coated tablets. Each tablet is round, biconvex, colored yellow. Dosage is exclusively 5 mg.

The price of medicine in Russian pharmacies differs slightly.

Composition of Relium

The active substance of the drug is diazepam. This component is a chemical derivative of 1,4-benzodiazepine. It has the ability to influence the GABAergic system, changing its sensitivity. The amount of diazepam in a tablet is directly proportional to its dosage. Auxiliary components are:

• potato starch;
• dry gelatin;
• yellow quinoline dye (E 104);
• talc;
• magnesium stearate;
• sodium starch glycolate.

The coating covering the tablet consists of cellulose acetate phthalate, polyethylene glycol 6000.

Pharmacodynamics and pharmacokinetics

The basis of the mechanism of action of Relium is the pharmacodynamic effects of diazepam. The medication has a direct effect on all components of the central nervous system. While taking the medication, changes occur especially actively in the centers of the brain responsible for emotionality - these are, directly, the limbic system and the hypothalamus.

Relium has an inhibitory effect on neurons of the GABAergic system located in the cerebral cortex, hippocampus, and cerebellum. As a result of this, a change in activity occurs various groups neurons: dopamine, norepinephrine, serotonin and cholinergic. Against the background of all these processes, the sensitivity and susceptibility to stimuli of the GABA receptor changes, which leads to an increase in its affinity for gamma-aminobutyric acid, which itself is an internal inhibitory transmitter.

Thanks to the combination of these processes, complex sedative effects occur: feelings of fear and anxiety are eliminated, muscle tension is reduced, and sleep improves.

Relium is absorbed by the mucous membrane gastrointestinal tract. Metabolism occurs in the liver. Here the active component begins to be divided into two components - N-desmethyl-diazepam and N-methyloxazepam. These, in turn, are converted to oxazepam, which has an affinity for glucuronic acid. Its half-life is a day or two. In the form of these metabolites, the drug is excreted from the body in the urine.

Peak drug concentration in circulatory system occurs an hour after taking the tablet. Relium has the ability to penetrate the blood-brain and placental barrier.

Indications and detailed instructions

The list of indications for the use of Relium is constantly expanding, thanks to comprehensive research conducted by both pharmacists and clinicians. Today, the list of conditions for which it is used is as follows:

• acute and chronic anxiety disorders, including those associated with the presence of concomitant diseases (oncology of any localization, hypertension);
• tetanus or diseases manifested by increased tone of skeletal muscles (arthritis, myositis, post-stroke condition) - in combination with the main therapy;
• spastic syndromes associated with dysfunction of the upper motor neuron in medulla oblongata(paraplegia, athetosis);
• withdrawal syndrome due to alcohol or drug addiction;
• insomnia associated with feelings of fear;
• epilepsy - as an additional component of the main treatment;
• convulsive syndrome.

Restrictions

It is prohibited to use it if at least one of the following conditions is present:

• hypersensitivity to the components of the drug;
• severe respiratory failure of both peripheral and central origin;
• myasthenia gravis;
• angle-closure glaucoma;
• hepatic or renal failure severe.

Separately, it is worth noting that Relium cannot be used in obstetric practice, since it has a detrimental effect on uteroplacental blood flow and, therefore, disrupts the intrauterine development of the fetus. Use of the medication after 34 weeks of pregnancy causes disturbances in the fetal heart rate and distress syndrome. Children born to mothers taking Relium lose their sucking reflex and develop respiratory problems.

Prescribing psycholytic drugs during lactation is also excluded. In this situation, it is necessary to decide: either the woman is breastfeeding the child or taking the drug. At the same time, these things are incompatible.

In pediatric practice it is used in isolated cases and very rarely. This is due to the fact that children need a smaller dosage, but there is no such alternative. And dividing one tablet into several parts does not always lead to the desired effect. Therefore, in this situation, the choice remains with the attending physician.

Dosage

The duration of treatment and dosage are determined solely by the doctor in each individual case. The treatment regimens indicated by the manufacturer are indicative and recommended. In practice, sometimes you have to adjust them. Let's look at the main ones:

1. Anxiety – 5-10 mg twice a day, regardless of meals.
2. Alcohol withdrawal syndrome - start with 10 mg three times a day, then 5 mg 4 times.
3. Hypertonicity – 2 tablets 3 times a day.
4. Trouble falling asleep - 2 tablets immediately before bedtime.
5. Premedication – 5-20 mg.

The duration of medication treatment depends on the diagnosis and can be 4-12 weeks. When treating elderly patients, it is necessary to take into account that you should start with a minimum dose and gradually increase it. It cannot be canceled abruptly. The dose reduction occurs in the opposite order.

Possible side effects and overdose

No matter how ideally the treatment regimen is selected, there is a risk of unwanted symptoms. The most common side effects are:

• from the central nervous system - headache, dizziness, pressure in the temporal region or the back of the head, disturbances in orientation in space, dyslalia;
• from the digestive tract - nausea, vomiting, constipation, diarrhea, epigastric pain, increased gas formation, yellowness of the skin;
• from the outside of cardio-vascular system– arterial hypotension;
• dermatological problems – itching, rash, dermatitis;
• the occurrence of paradoxical reactions - hallucinations, delirium, increased tone, insomnia (such symptoms are a direct indication for discontinuation of the medication).

Symptoms of a drug overdose are:

• excessive sleepiness;
• weakness;
• disturbance of consciousness;
• decreased reflexes;
• apnea;
• coma.

When the first signs of an overdose appear, the patient should be given immediate assistance, following the following algorithm:

1. Stop taking the drug.
2. Give the person a comfortable position.
3. Rinse the stomach with plenty of distilled water.
4. Give any sorbent ( white coal, Activated carbon).
5. While providing assistance, be sure to monitor your pulse, blood pressure, and respiration.
6. Call ambulance(if signs appeared at home), which will do venous access to provide adequate infusion therapy.
7. Use a specific antidote - flumazenil (against the background of its use high risk occurrence of seizures).

Interaction with other drugs and special instructions

Relium should be used with extreme caution simultaneously with phenothiazine derivatives, narcotic analgesics, hypnotics and antidepressants. Such combinations enhance the effect of the main component of Relium - diazepam.

It is prohibited to drink alcohol and narcotic substances during treatment with Relium, since in such a situation it is significantly inhibited nervous system and a syndrome of pathological intoxication occurs, which does not depend on the amount of alcohol consumed. This condition is quite often fatal.

Oral contraceptives (COCs) inhibit the effect of the medication. The process of smoking during the treatment period has the same effect.

Concomitant use with other drugs does not cause significant changes in the pharmacodynamics of Relium. However, clinical trials on this matter are ongoing.

Any treatment for this medicine must be carried out under the strict supervision of medical personnel. It is prescribed with caution for the treatment of depressive disorders, since there is a high probability of suicidal tendencies in the patient’s behavior.

Clinical and laboratory parameters of the blood and urine system should be monitored periodically during therapy. Special attention should be given to changing liver tests. The drug is withdrawn gradually.

Analogues of the drug

It is worth noting that Relium has a sufficient number of generics (medicines similar to it in chemical structure and therapeutic effect). Let's look at the most commonly used ones:

1. – available in two dosages: 5 and 10 mg per tablet. All pharmacodynamic and pharmacokinetic properties are similar to those of Relium. The medicine is its complete analogue. Produced in Ukraine by Interkhim ODO. Its price is a little cheaper.
2. Diazepex is one of the few anxiolytics available in liquid form. 1 ml of solution for injection contains 10 mg of diazepam. It also contains 96% ethyl alcohol. It is administered intramuscularly. It can also be taken orally in selected cases. Manufacturer – JSC “Kalceks”, Latvia.
3. Sibazon - also available in the form of a solution for injections. 1 ml contains 5 mg of the active ingredient (diazepam). Indications for use are similar to those of the drug in question. Pharmacodynamics are no different. It is used intravenously slowly or by drip, in rare cases - intramuscularly. Is a drug emergency care when status epilepticus occurs. Also, unlike all other drugs in this group, it is used when an attack of eclampsia occurs during pregnancy or childbirth.