What effect does Corvalol have? Corvalol overdose: symptoms, consequences, treatment. Contraindications and side effects

For sleep disturbances, heart pain and hangover, take Corvalol. But will this help? medicinal product to recover from drinking alcohol, is it possible to drink it with a hangover?

Corvalol for hangover

The drug Corvalol is used as a sedative, antispasmodic, facilitating sleep, reducing the excitability of the nervous system, eliminating the symptoms of cardiovascular disorders.

When you have a hangover, these properties of Corvalol are used to fall asleep, calm down, and give your body and brain rest. But is it possible to take Corvalol after drinking alcohol, with a hangover?

The action of Corvalol is due to the properties of the active components included in its composition:

bromoisovaleric acid ester;
phenobarbital;
ethanol;
peppermint oil.

Of these drugs, the properties of phenobarbital should be especially considered. This compound is a psychoactive substance and is a depressant, like alcohol.

The effect of depressants is to slow down brain activity, reducing the speed of transmission of nerve impulses. Sleep caused by the action of phenobarbital will not bring long-awaited rest; it differs from physiological, normal sleep.

When taking medications with phenobarbital, the rapid phase of sleep is shortened and the stage of deepest, slow-wave sleep is reduced. Such a vacation will not bring relaxation to a person and will not allow him to restore his working capacity.

Mechanism of action

The action of Corvalol is determined by the properties of its components. Peppermint oil can be beneficial for hangovers. This substance irritates the cold thermoreceptors located in the oral cavity, which causes reflex expansion blood vessels heart, brain.

But the effect of phenobarbital in combination with alcohol inhibits the activity of the central nervous system. If there is a small amount of alcohol in the blood, the absorption of phenobarbital is accelerated, and the accumulation of phenobarbital in the brain occurs faster.

Even a small dose of phenobarbital in the presence ethyl alcohol can cause inhibition, depression of brain centers associated with unconditioned reflex activity. A high dose of the drug, due to the phenobarbital it contains, can sharply lower blood pressure and weaken the tone of the smooth muscles of the digestive tract.

Does Corvalol help with a hangover? It is possible to relieve pain in the heart, but consuming drops in this state can cause poisoning, apathy, and shut down the vital centers of the brain responsible for breathing and heart contraction, which will lead to death.

A hangover is accompanied by severe liver damage. Under such conditions, the effect of phenobarbital is enhanced, the drug circulates in the blood longer without being processed.

If the concentration of alcohol in the blood during a hangover is high, phenobarbital will be absorbed more slowly in the stomach due to inflammation of the mucous membrane caused by the impact of the heavy dose of alcohol taken the day before.

Indications

Corvalol helps symptomatically with diseases such as:

hypertension;
heart rhythm disturbances;
anxiety;
hypochondria;
restlessness, irritability.

The effect of the drug is temporary, eliminating only the symptom, without curing the cause of the disease.

Corvalol, thanks to peppermint oil, eliminates spasm of the blood vessels that feed the heart muscle, thereby relieving a person of the pain of a hangover; it helps if it hurts in the heart, squeezing the head “like a vice.”

If the pain in the heart is unbearable, rapid heartbeat, severe colitis in the chest area and there are no other medications, you can take Corvalol after a hangover in the usual dosage as first aid. But we cannot expect that this will be enough. The effect of this medicine is only enough to reduce the pain, but not to cure the cause that caused it.

Corvalol will not cope with angina pectoris and will not protect against a possible heart attack. You can’t hope that they can cure heart pain from a hangover; you should definitely consult a doctor.

Contraindications

Corvalol is contraindicated for kidney problems. You should not drink drops if your heart rate decreases. If you have a hangover, a weak, low pulse (less than 60 beats per minute), low blood pressure, then taking Corvalol will not help, but will only worsen the patient’s condition.

Corvalol contains phenobarbital, and this compound is prohibited for use in alcoholism and drug addiction.

Feelings of tightness in the chest, anxiety, sleepless nights, heart pain and heavy breathing are the main prescriptions for which Corvalol helps. Most people think this drug almost a panacea for all ills and they always keep a bottle or two of strong-smelling drops in the medicine cabinet. However, few people think about what this remedy is, what is in its composition, what its therapeutic effect is based on, and, most importantly, how to use it correctly.

Corvalol - composition

In pharmacology, the drug Corvalol is produced in both tablet and liquid form. However for home use alcohol-containing drops are more common, due to their fast action. But it’s more convenient to take the tablets with you. The basic composition of the two types of the drug is the same:

Ethyl bromizovalerate has a strong sedative, antispasmodic and soporific effect.
Luminal (phenobarbital) has a depressant effect on the central nervous system, thereby causing drowsiness, calming and reducing reaction. The concentration of the drops affects the effect from a weak sedative to a strong hypnotic.
Peppermint ester in Corvalol has wide range actions:

dilates blood vessels;
carminative;
spasmolytic;
antiseptic.

Corvalol tablets - composition

Corvalol tablets are available in packs of 10, 30 or 50 pieces in cellular blisters. The active ingredients contained in the drug per tablet have the following proportions:

mint essential oil– 580 mcg;
Luminal – 7.5 mg;
ethyl bromizovaleriant – 8.2 mg.

In addition, a number of auxiliary ingredients include Corvalol. The composition of the tablet is also supplemented with substances that ensure proper pharmachologic effect medications taking into account their pharmacokinetics:

magnesium stearate – 1 mg;
beta-cyclodextrin – 55.5 mg;
magnesium aluminum metasilicate – 4 mg;
potato starch – 37.5 mg;
milk sugar – 83 mg;
talc – 2 mg.

Corvalol - composition in drops

Corvalol drops are a colorless liquid with a characteristic odor; more often than tablets, they are used in home treatment. The medicine is produced in vials with droppers of 25 or 50 ml. They are based on:

water – 100 ml;
oils – 0.14 g;
ethyl alcohol – 58 ml;
caustic soda – 0.31 g;
phenobarbital – 1.8 g;
ethyl bromoisovalerate – 2 g.

Why take Corvalol?

To the question “what does Corvalol help with?” Most people taking this drug will answer that they take it for heart pain. However, it is difficult to call Corvalol Forte a medicine that can cure even a heart disease or any other disease. This remedy is aimed at eliminating certain symptoms of nervous system disorders. Yes, Corvalol is able to relieve heart pain, but only that associated with anxiety, worries, and stress. However, he cannot stop the heart attack pain.

The main symptoms that Corvalol helps with are:

anxiety;
nervousness;
panic;
consequences of nervous disorders.

Corvalol for VSD

- This is a clear example of the fact that all diseases begin with nerves. Basics treatment of VSD is aimed at relieving symptoms, which is what Corvalol helps with in the best possible way. This drug fights nervous disorders, which, in essence, is VSD:

Peppermint essential oil dilates the blood vessels of the heart.
Bromine fights anxiety and stress.
Phenobarbital is a powerful tranquilizer. It has strong hypnotic and sedative qualities.
Corvalol has worked well for tachycardia.

Corvalol for blood pressure

Due to the properties of the components of Corvalol to have an inhibitory effect on the vasomotor center and an antispasmodic effect on the heart vessels, an unexpressed hypotensive effect of the drug on the body is achieved. However, the fact remains that Corvalol high blood pressure If it helps, it is very weak. So rely on this remedy when arterial hypertension, requiring completely different treatment, is not worth it. Yes, Corvalol is able to reduce blood pressure, but it cannot stop it, nor can it maintain normal blood pressure.

Corvalol for insomnia

Is it possible to take Corvalol for insomnia? Sleep disturbance is a direct indication of taking this drug in any form, be it drops or tablets. However, it is worth keeping in mind that the dose of the drug, just like the course of treatment, is selected individually in each specific case. According to the instructions, you should drink Corvalol as follows:

If you drink the solution, then 20-25 drops dissolved in 50 ml of water will be a sufficient dose. However, you should not take the medicine more than three times a day. In case of severe stress and tachycardia, the dose of the drug can be increased to 40 drops per dose, but no more.
If you take Corvalol in tablet form, then one tablet three times a day before each meal is enough. For severe stress and tachycardia, you can increase the dose to 3 tablets.
Children over 6 years old should not exceed the daily dose of 12 drops.
The course of taking Corvalol can vary from 1 week to 2 months, according to the doctor’s instructions.

Corvalol for heart pain

The use of Corvalol drops is very often associated with cardiac pathologies. However, in the presence of structural cardiac disorders, associated, for example, with atherosclerosis, dripping these drops over and over again in the hope of healing is not only pointless, but also fraught. Yes, Corvalol can and will help with arrhythmia, calming the nerves and thereby relieving the symptom, but the disease will remain and worsen over time, even to the point of fatal consequences.

Corvalol is a symptomatic remedy and can relieve the negative manifestations of stress and neuroses, so doctors often recommend taking it for:

Functional cardiac disorders:
- tachycardia;
- pain from overexertion and anxiety.
Overexcited with vegetative symptoms:
- cardiopalmus;
- sweating;

How to take Corvalol?

Depending on the reason for which Corvalol is prescribed, the dosage of the drug may be prescribed differently by the attending physician. In this case, the doctor must take into account general state patient, be confident in the absence of contraindications and violations on the part of of cardio-vascular system. If, while taking Corvalol, the patient’s condition worsens: chest pain appears, anxiety increases, or abdominal discomfort is observed, then the medication should be stopped and immediately contact your local physician.

How to take Corvalol tablets?

A more convenient form of medication to take is tablets. How to take Corvalol tablets? This drug is prescribed 1, less often 2 tablets three times a day. They should be taken before meals with plenty of water. In case of severe symptoms, for example, with tachycardia, it is possible to increase the single dose of the drug to three tablets per dose.

How to take Corvalol drops?

An alcohol solution in a bottle with a dropper is the most common form of the drug Corvalol. The use of this product is dosed in drops. At the same time, they can be applied either to a piece of sugar or dissolved in a small amount of water. This sedative is available without a prescription, so people mostly drink Corvalol, dosing the drops themselves according to the instructions:

Dissolve 15-30 drops of the drug in a glass of water and take three times a day.
For tachycardia, a single dose can be increased to 40 drops.
Children's daily dose– 3-12 drops, depending on the clinical picture of the disease and the age of the child.

Corvalol - side effects

Regardless of the fact that you can easily count a dozen or two symptoms that Corvalol helps with, this drug still has many negative aspects and consequences that quickly disappear when the drug is discontinued or its dose is reduced:

drowsiness;
decreased concentration;
allergy;
dizziness;
digestive system disorders;
slow heart rate;

Long-term use of Corvalol can also lead to unpleasant consequences:

addiction;
withdrawal syndrome;
addiction.

When bromine accumulates in the body, the following symptoms may occur:

depression;
rhinitis;
diathesis;
ataxia;
conjunctivitis;
impotence;
respiratory diseases;
kidney and liver poisoning.

depression of the central nervous system;
ataxia;
hypotension;
overexcitement;
vertigo;
general weakness;
bromism;
nystagmus.

In case of an overdose of Corvalol, emergency gastric lavage is performed and symptomatic therapy. When the central nervous system is depressed, stimulant drugs are prescribed:

Caffeine;
Niketamide;
Cordiamin.

Corvalol - contraindications

Corvalol contains Luminal, as a result, patients taking this drug are advised to refrain from potentially hazardous activities that require high level attention and concentration, quick reaction. For example, when driving transport or other complex mechanisms or when working at height.

Is Corvalol safe for pregnant women? The absence of alcohol in the component composition of the tablets allows it to be taken by some groups of patients. However, pregnant women are not included in this list due to the presence of phenobarbital in the drug, be it tablets or in the form of an alcohol solution. In general, Corvalol has many contraindications, which to a greater extent associated with phenobarbital, ethanol and bromine, which can accumulate in the body:

individual intolerance to the ingredients of the drug;
severe liver and kidney dysfunction;
perinatal period and lactation period;
epileptic syndrome and seizures;
alcohol addiction;
consequences of traumatic brain injury.

Persons under 18 years of age should take the drug with caution.

Corvalol - analogues

Corvalol drops and tablets have numerous analogues. Despite the different compositions and component inconsistencies with each other, the sedative effect of all these drugs is pronounced:

is a synonym for Corvalol. This drug was invented in Germany in pre-war times and is still produced by only one company.
Novo-passit has a completely natural composition - herbs infused with alcohol, which together show a powerful sedative effect.
Barboval.
Adonis-bromine.

An overdose of Corvalol is intoxication of the body with this drug and its constituent components. And if most patients can tolerate such poisoning relatively easily, some may experience serious complications (including death).

In general, an overdose of Corvalol is dangerous only for those people who are allergic to this substance and the accompanying components of the drug. And most often, an overdose is caused not by accident, but by the patient’s purposeful intake of a high dose of medication to enhance its effect.

In this article we will talk in detail about the dangers of an overdose of Corvalol and what to do if its first signs appear. We will also talk about what is the normal dosage of this drug.

Corvalol is almost the most popular drug in the CIS countries. About 150 million packages of this medicine are purchased annually in the CIS countries. It is not always bought for an existing illness; in the vast majority of cases, Corvalol is taken “just in case.”

Corvalol does not directly affect the heart, although many patients think otherwise. In fact, this drug has a sedative effect, calming nervous system patient.

Self the medicine consists of the following components:

α-bromoisovaleric acid ethyl ester;
filtered water;
sodium hydroxide;
phenobarbital;
peppermint oil.

A serious disadvantage of this medicine is the patient's addiction. Moreover, the patient not only begins to take Corvalol daily, but also increases the dose in the hope of a more effective and prolonged effect of the medicine.

Purpose and benefits of use

The constituent components of Corvalol have a pronounced effect on many human diseases (mainly neurological). So Corvalol is useful to combat the following problems:

Disorders of the cardiovascular system (arrhythmias, tachycardia).
Insomnia and irritability.
Hypochondria and suspiciousness.
Vegetovascular dystonia.
With a low, stable rise blood pressure.

It is worth noting that this medicine is usually not prescribed as self-treatment of the diseases listed above, but only as an auxiliary treatment. Corvalol enhances the overall effect of therapy, and in case of acute onset of the disease (for example, sinus tachycardia or panic attack) it is a means for quickly stopping an attack.

Who prescribes the course of treatment?

Although this medicine can be purchased without a prescription, you should still consult a doctor before purchasing it. If medicine is required for the treatment of cardiovascular diseases, then you need to consult a cardiologist or vascular surgeon.

If you have neurological diseases (VSD, hypochondria, panic attacks), you should consult a psychotherapist or neurologist before purchasing the drug. For insomnia, consultation should be carried out either with a general practitioner or a neurologist.

It is important to understand that pharmacists at a pharmacy do not have the authority to prescribe medications to clients. Therefore, purchasing Corvalol based on the opinion of a pharmacist is dangerous.

Harm from taking Corvalol

In addition to the previously described disadvantage of addiction, Corvalol has other significant disadvantages. So the combination of phenobarbital with alcohol solution inhibits the functions of the central nervous system and impairs coordination of movements.

Intoxication with these components of Corvalol, which occurs during an overdose, can even cause death. The critical dose that can already cause death is half a standard bottle of Corvalol.

When interacting with tranquilizers and other sedatives, complications can also arise. Thus, phenobarbital, which is a component of Corvalol, when in contact with the listed drugs, significantly enhances their effect.

As a result, the effect of sedatives intensifies so much that the patient becomes apathetic, drowsy and lethargic. Stupor and deep pathological sleep are even possible.

What is obvious is that all of the listed complications of taking Corvalol are in one way or another associated with its improper use. A moderately increased dosage or combination of the drug with its analogues can lead to serious consequences, sometimes even causing death (especially in elderly patients).

Normal: how many drops of Corvalol can you drink?

The drug is approved for use by patients who are over 18 years of age. The standard dosage of the drug applies to all ages starting from 18 years. That is, simply put, it is universal.

No fear drug can be taken in the following doses:

For neurological diseases: the dose is 15-20 drops, no more than three times a day.
For diseases of the cardiovascular system: you can drink no more than 40 drops per day, no more than three times a day.
For prevention panic attacks: You can take 10-15 drops per day.

In some cases, the dose can be slightly increased, but only after mandatory consultation with a doctor. Ignoring this rule will result in serious consequences (including death).

How many days can you take Corvalol?

The consequences of long-term use of Corvalol have been studied quite well and are currently considered harmless. The main consequences of long-term use are only dry mouth and psychological dependence on the drug.

The drug does not have a toxic effect on all internal organs in general, and on the kidneys and liver in particular. Only elderly patients may experience chronic intoxication bromine (it is contained in phenobarbital, a component of Corvalol).

This condition rarely develops into a serious independent disease. Typically, bromine intoxication is characterized by drowsiness, depression and apathy. If these symptoms appear, the drug should be temporarily discontinued and consult your doctor.

Lethal dosage

The maximum dose of medicine at which the body can cope with the load and remove excess is 150 drops. However, in those patients who have chronic renal or liver failure, this dose can be lethal.

The consequences of taking a dose exceeding 150 drops are severe poisoning and with a high probability of death (even in healthy people). It is estimated that lethal dosage is 0.1-0.3 grams per 1 kilogram of weight patient. On average this is 20 grams of medicine.

The causes of mild and severe Corvalol poisoning are not as simple as it seems at first glance. The main component contained in the medicine is absolutely safe in recommended doses, but high doses- deadly. To be more precise, we are talking about phenobarbital.

In high doses, it strongly inhibits psychomotor reactions and causes coordination problems. In ultra-high doses, it disrupts the conduction of the nerves of the heart, causing it to stop.

Moreover, this component can be dangerous in normal doses, but only in some cases. Namely:

with concomitant use of alcoholic beverages;
when combined with pure alcohol;
when used with tranquilizers;
when used with sedative medications;
when used with antiemetic medications.

How dangerous is an overdose?

Poisoning with this drug due to an overdose is fraught with both serious health consequences and, in more rare cases, death. Overdose is especially dangerous in cases where alcohol was taken the day before.

Alcohol is a catalyst for the components of Corvalol, which only aggravates the situation in case of overdose. An excessive dose of Corvalol and drunk alcohol often cause collapse, severe coma and death.

Poisoning with this drug is also insidious because the patient is in deep sedation, similar to complete apathy and stupor. As a result, the patient does not even realize that he is in a critical condition, so he cannot orient himself in time and call ambulance.

Symptoms of an overdose of Corvalol

Symptoms acute intoxication Corvalol are quite expressive, so many doctors, even without clinical blood tests, will be able to accurately diagnose.

Signs of such intoxication in the easiest version the following:

drowsiness;
general weakness;
lethargy and absent-mindedness;
slight decrease in muscle strength;
difficulty pronouncing complex sentences.

Symptoms of moderate intoxication:

prolonged pathological sleep (it is very difficult to wake the patient);
salivation;
severe muscle weakness;
convulsions;
lack of urge to urinate;
pupil dilation.

Symptoms of severe poisoning:

lack of consciousness;
coma;
breathing disorders (the patient breathes shallowly, often);
drop in blood pressure;
wheezing in the lungs;
tachycardia with a heart rate exceeding 130 beats;
cyanosis of the skin.

The danger of Corvalol (video)

First aid and treatment

First aid is possible only in case of a mild overdose of Corvalol. In this case, it is necessary to thoroughly lavage the patient’s stomach as quickly as possible. To do this you need to give him about 20 grams activated carbon and a liter of warm liquid.

A laxative (saline-based) and cleansing enemas would be useful. After bowel cleansing, the patient should be given an enveloping drink.

In case of moderate or severe overdose, you need to call an ambulance as quickly as possible. Attempts to cleanse the patient’s stomach and intestines on their own are futile, since he is not able to take a sip.

Which doctor should I contact?

A general practitioner, toxicologist and gastroenterologist can treat Corvalol intoxication. Therefore, when calling an ambulance you need to follow some rules.

So the dispatcher should be asked to send a highly specialized team of doctors (therapist, toxicologist or gastroenterologist). The dispatcher should also be informed that it is not a linear team that is required, but a resuscitation team.

The fact is that linear ambulance teams do not have special equipment on board to restore the patient’s blood pressure and heart rate. Only specialized resuscitation teams (so-called reanimobiles) have such equipment.

Corvalol is a sedative, popular in the countries of the former USSR, but prohibited in Poland, Germany, the USA, Norway, and Lithuania. Prohibitive measures were taken due to the presence of the psychoactive compound phenobarbital in Corvalol, as well as a toxic bromine-containing component.

What makes the drug popular among Russians, who drink an average of 40 train tanks of medicine a year? And today we will talk in more detail about the indications and instructions for using Corvalol drops and tablets, its price, reviews, composition, analogues.

Features of the drug

The combined medicine Corvalol exhibits a sedative, vasodilating effect, is used against insomnia, as a sedative for stress, emotional stress. The Ministry of Health of the Russian Federation recognized Corvalol as a drug with a low content of psychoactive substances and allowed it to be sold without a prescription, planning in the future to refuse to prescribe this drug to patients, replacing it with more modern medicines.

When using Corvalol, you must remember that this remedy does not treat diseases of the heart or nervous system, but only eliminates the manifestations of the disease.

This video will tell you about the dangers and benefits of Corvalol:

Composition of Corvalol

Active ingredients of the drug Corvalol:

ethyl ester of alpha-bromovaleric acid (ethyl bromoisovalerate);
phenobarbital;
peppermint leaf oil.

Excipients of Corvalol drops are:

ethanol;
sodium hydroxide;
purified water.

Auxiliary components in tablets are betadex, lactose, potato starch, magnesium salts.

Dosage forms

Corvalol is produced in alcohol drops and tablets for lozenges sublingually (under the tongue). The tablets are packaged in blisters of 10, 30 and 50 pieces.

Alcohol drops are packaged in dark glass bottles with a capacity of 15 ml, 25 ml, 50 ml. The alcohol tincture has a strong, specific aroma. The average price of Corvalol tincture is:

for a container of 15 ml - 16 rubles;
25 ml – 23 rub.;
50 ml – 33 rub.

Prices for Corvalol may vary from 9 to 120 rubles. The cost of 10 tablets of Corvalol is 18 rubles.

pharmachologic effect

Corvalol belongs to the group of sedatives, is combination drug, exhibiting a calming, antispasmodic, vasodilating effect that helps normalize sleep.

The video below will talk about both the composition and properties of Corvalol:

Pharmacodynamics

The properties of Corvalol are determined by the total effect of its active components.

The main active ingredient is ethyl bromizovalerianate. This compound eliminates smooth muscle spasm internal organs, calms and relaxes the nervous system.
Phenobarbital has the ability to act on the central nervous system, directly removing the excitation of the nerve centers of the brain. The calming effect of phenobarbital is less pronounced.
Peppermint oil, irritating “cold” sensitive nerve endings oral cavity, selectively dilates the blood vessels of the brain, coronary vessels that feed the heart muscle. The oil exhibits choleretic and antiseptic activity and helps eliminate flatulence.

Pharmacokinetics

The action of the drug in tablets begins in the oral cavity. Positive influence medications for the patient’s well-being when the tablet is dissolved under the tongue, it manifests itself almost instantly.

The effect of Corvalol when taken in the form of drops is noticeable within 10-30 minutes. The duration of action of the medicine when taken in tablets and drops is 6 hours.

From active ingredients Corvalol The pharmacokinetics of phenobarbital have been studied most of all. This compound is well absorbed and has the ability to accumulate in the body. The half-life of phenobarbital is 2-4 days. The compound decomposes into simple components in the liver and is excreted by the kidneys in the form of a glucuronide, partially (25%) unchanged.

In old age, with impaired liver function, the half-life of the drug from the body is prolonged. This requires adjustment of the dosage of the drug towards reduction, increasing the intervals between doses of the medication.

We will tell you further what Corvalol helps with and how to take it.

Indications

Functional disorders of the cardiovascular system;
sleep disorders;
neurosis-like conditions;
, spasms of heart vessels;
intestinal spasms.

Instructions for use

For adults, Corvalol tablets are prescribed 1 tablet for an attack of tachycardia or spasms of blood vessels. If necessary, the dosage of the drug can be increased to 3 tablets.
Alcohol tincture of Corvalol is taken with water, 10-30 drops or on a piece of sugar. The maximum single dose of tincture should not exceed 50 drops.

The doctor chooses the treatment regimen individually. The drug is taken no more than 3 times a day, the duration of treatment depends on the patient’s condition and the dynamics of the disease.

According to the instructions, Corvalol is not allowed to be used for treatment under 18 years of age. In acute situations, the doctor may prescribe the child to take the drug at the rate of 1 drop for each year of age.

Children can be given medicine no more than once a day, in the amount of 3-15 drops. Treatment should be supervised by a doctor due to the lack of data on the effect of Corvalol on the children's body.

Contraindications

Hypersensitivity to the components of the drug;
age under 18 years;
pregnancy, lactation;
lactose intolerance;
heart disease;
renal, liver failure.

Corvalol is not approved during pregnancy due to the ability of its phenobarbital component to penetrate the placental barrier and have a teratogenic effect on the fetus. Taking medication during pregnancy can provoke the appearance of congenital anatomical deformities and disruption of the formation of internal organs.

Side effects

The most dangerous side effect of Corvalol is psychological addiction to phenobarbital. And, if physical dependence on phenobarbital is weakly expressed, then mental dependence forms quickly.

Mental dependence forces you to take the treasured bottle with you everywhere, in all difficult situations to resort to its magical calming effect, simultaneously increasing the concentration of bromine contained in ethyl bromoisovalerate in the body.

Signs of bromine poisoning include:

inhibition of central nervous system functions;
tendency to depression;
confusion;
lack of coordination.

Taking Corvalol can cause side effects from the side:

nervous system - inability to concentrate;
of cardio-vascular system - ;
digestive system - nausea, vomiting, stomach pain.

special instructions

The drug, mainly due to the presence of phenobarbital in its composition. This component is destroyed in the liver, like alcohol, which leads to increased stress on it.

Phenobarbital, which is part of Corvalol, has the property of enhancing the effect of sedatives. Combine Corvalol with caution with sleeping pills and analgesic drugs; it is not recommended to take the drug with drugs that metabolize in the liver - hormonal drugs, antibiotics, contraception.

Overdose

Exceeding the dose of Corvalol is accompanied by dizziness and inhibition of brain activity. If the symptoms of an overdose of Corvalol do not go away after stopping the drug, the patient’s stomach is washed and an ambulance is called.

In severe conditions, the following are possible:

neuromuscular disorder of muscle coordination -;
, increased heart rate;
a sharp drop in blood pressure;
, coma.

Long-term use of the drug can cause dependence, and if treatment with Corvalol is discontinued, it can cause withdrawal syndrome.

Not everyone knows how to drink Corvalol with maximum health benefits. This product is in every home medicine cabinet. Despite the fact that the drops have a wide range of uses, there are certain contraindications. An overdose of Corvalol can lead to serious negative consequences.

Corvalol - a familiar stranger

Corvalol or its analogue Valocordin is considered something like ordinary Valerian. However, this is not the case. Corvalol is a complex vasodilator medicine, which has a calming effect. First of all, it is prescribed for chronic insomnia, neurotic and hypochondriacal syndrome, early stage hypertension. As an antispasmodic, Valocordin or Corvalol is used to get rid of stomach and intestinal colic and relieve symptoms functional disorders of cardio-vascular system.

Corvalol contains synthetic and plant components:

Ethyl bromoisovalerate. It acts predominantly on nerve receptors in the mouth and pharynx. The substance has an inhibitory effect on the activity of the cerebral cortex and subcortex, effectively relieves spasms, and has a relaxing and calming effect on the entire body as a whole.
Phenobarbital- potent psychotropic substance. It has a sedative effect, quickly and well inhibits the transmission of excitation impulses to the cerebral cortex and subcortical nerve centers. Thanks to this, Corvalol exhibits a mild hypnotic and sedative effect. A slight hypotensive effect may be observed, but most often it is short-lived.
Peppermint oil- a herbal component, has an antispasmodic and antiseptic effect, has a calming effect on smooth muscles gastrointestinal tract. Often used to eliminate dyspeptic symptoms in the gastrointestinal tract.
Ethyl alcohol 95% makes up about 80% of the composition of the drug. This is one of the reasons why Corvalol is extremely rarely prescribed to children and pregnant women, as well as to people suffering from alcoholism.

Indications for use

Corvalol is not a medicine that treats a specific disease. The drug can only alleviate the patient’s condition in a certain situation that requires quick help. It is prescribed for:

chronic insomnia (at night, until the usual sleep rhythm is normalized);
situational neurosis-like state, feelings of anxiety, emotional outburst;
nervous overstrain, prolonged stress;
tachycardia as a situational aid that does not replace treatment with basic antiarrhythmic drugs;
nervous spasms of the stomach and intestines.

Release form and application

The drug is released in 2 dosage forms- drops and tablets. If necessary, the tablet can be placed under the tongue and wait until it is completely absorbed. It is believed that since sublingual tablets do not contain alcohol, they can be taken by alcoholics. The statement is only partly true, because The composition contains phenobarbital, which alcohol-dependent people should not use. The daily dosage of tablets is determined by your doctor.

Corvalol in drops is considered more popular. They are drunk by dissolving them in a small amount of water (usually 1 tablespoon) before meals. Doctors advise: before swallowing, you should hold the medicine in your mouth for a while and allow some of the drug to be absorbed. This way it will work faster. The dosage is determined by a specialist.

For patients with normal level blood glucose, you can take Corvalol by dropping it on a piece of sugar, which should be kept in the mouth until completely dissolved, swallowing the syrup with the medicine. This method is contraindicated for diabetics.

Taking Corvalol

In case of severe tachycardia, the usual dose can be increased, but this is a last resort. You shouldn't use it too often. If this dose does not help, the patient needs to remember that it is better to consult a doctor than to continue experimenting with his own health.

When taken correctly, the effect of the medicine occurs within 15-20 minutes. It is not recommended to use the drug more than 3 times a day.

Corvalol and alcohol

Many people are interested in how Corvalol and alcohol combine with each other. Based on numerous studies, experts do not recommend using them together. One of the contraindications for taking Corvalol is chronic alcoholism. Valocordin and alcohol drunk at the same time can cause irreparable harm to health.

Phenobarbital, which is part of the product, has zero compatibility with alcohol. This is a psychotropic substance. Experts compare the side effects of its excessive use to delirium tremens (delirium tremens) with all the unpleasant consequences, including painful body aches, impaired brain function, coma, and increased hangover. The lethal dose has not yet been determined.

Alcohol increases the toxicity of Phenobarbital several times. Taking Corvalol with alcohol causes a heavy blow to the liver, where alcohol accumulates. Both substances significantly reduce the speed of the body's reaction to external stimuli. This means that after them joint reception Coordination of movement may be impaired, and spatial disorientation occurs. All this is fraught with injuries and falls, especially on the street and in public places.

Taking Corvalol with alcohol can cause a severe blow to the liver

Experienced people often claim that Corvalol with a hangover helps to quickly return to normal. But this is a very controversial method of treating this condition. The drug is prohibited for use by persons suffering from severe hepatic and renal failure, these are the diseases that occur in those who abuse alcohol.

If you still need to relieve tachycardia, anxiety, neurotic manifestations, or hand tremors after binge drinking, you can take Valocordin or Corvalol for a hangover. However, this should be done no earlier than 8 hours after the last drink, when the concentration of alcohol in the blood has decreased significantly. The dose of Corvalol should not exceed 50 drops (with strong heartbeat), it is optimal to take 30 drops per 50 ml of water. It is best not to leave the house after this, but to go to bed.

Valocordin and Corvalol should not be taken by those who are diagnosed with alcoholism, because These medications contain 95% alcohol.

If you have a hangover, taking Corvalol and Valocordin is prohibited. It is better to choose other medications.

Contraindications for use

Thanks to its composition, Corvalol is widely used to eliminate a number of painful symptoms. However, thanks to the same components, it cannot be used in a number of cases:

Pregnancy. The components of the drug penetrate the placenta and negatively affect the formation of the fetus. They reduce blood clotting and contribute to the appearance of limb cramps in the newborn. In the first weeks of life, the baby may be very excitable and suffer from sleep disturbances. It is necessary to stop taking this medicine and its analogues for early stages pregnancy. The attending physician will help you choose a less toxic medicine for the expectant mother.
Lactation.
Severe liver and kidney failure.
Chronic alcoholism.
Age up to 18 years.
Epilepsy and traumatic brain injury.

Side effects

The main causes of negative consequences are an overdose of Corvalol and long-term use of the drug.

Side effect: depression

The patient has:

periodic causeless dizziness;
constant drowsiness during the day and wakefulness at night;
deterioration of attention, inability to concentrate;
depression and amnesia;
impaired coordination of movements;
incoherent speech;
allergic rhinitis;
conjunctivitis;
symptoms of bromine poisoning.

If an overdose of Corvalol leads to such consequences, you should immediately stop using it and replace it with another safer drug. A lethal dose of the drug is rarely achieved at home, even if the drug is taken with alcohol.

Taking the medicine for a very long time sooner or later becomes addictive. This is especially true for older people, who often cannot imagine spending a day without a dose of Corvalol. Once they get used to the medicine, it is difficult for them to free themselves from addiction. The accumulation of bromine in the aging body can exacerbate the course of chronic diseases. Therefore, it is important to explain that it is better to abandon Corvalol or Valocordin in favor of other modern, safe and effective drugs. As a last resort, you need to reduce the daily dose.

Corvalol should not be used by anyone who drives a car. After taking the drug, doctors strongly do not recommend driving, because the product contains alcohol. For drivers, taking this medication is possible only in the evening or at night. Morning use is contraindicated.

Conclusion

Corvalol, Valocordin and other sedatives have been popular in medicine since the middle of the last century. Now they can be bought in Russia, Belarus, Ukraine, and some Asian countries. In Europe and America, these drugs are prohibited for consumption and import. They abandoned these drugs long ago in favor of more modern ones.

If treated incorrectly with Corvalol, the consequences can be very serious. Considering the fact that it cannot be used by drivers, zero compatibility with alcohol, and the effect of accumulation in the body, we can conclude that this cheap medicine is not so necessary in a home medicine cabinet. With a wide selection of modern sedatives, it is quite possible to choose an effective and safe drug to replace the outdated Corvalol. But it is best to consult a doctor who will help you make the right choice.