Ethyl alcohol (70%). Medicines Effect on the ability to drive vehicles and machinery

Instructions for medical use

medicine

Ethanol70%

Cethyl pirt 90%

Tradename

Ethyl alcohol 70%

Ethyl alcohol 90%

International nonproprietary name

Dosage form

Liquid 70% and 90%, 50 ml

Compound

1 liter of the drug contains

Description

Colorless, transparent, volatile, flammable liquid with a characteristic alcoholic odor and pungent taste.

Pharmacotherapeutic group

Other antiseptics and disinfectants. Ethanol.

ATX code D08AX08

Pharmacological properties

The local and reflex action of ethanol consists of irritant, astringent and antiseptic effects. After exposure of the skin to concentrated solutions ethyl alcohol(70% and 90%) an astringent effect occurs due to the denaturation of protein tissues. The tanning effect of alcohol on the skin reduces its sensitivity and sweating, promoting analgesia and stopping itching.

The antiseptic effect is associated with the denaturation of cytoplasmic and membrane proteins of microbial cells. The bacterial flora is most sensitive to ethanol. The most optimal concentration for the bactericidal effect of the drug is 70%. At higher concentrations, the tanning (astringent) effect of alcohol on tissue structures complicates its diffusion, and the depth of the antiseptic effect decreases.

Indications for use

IN medical practice Ethyl alcohol is used primarily as an external antiseptic and irritant for rubdowns and compresses.

Treatment of the surgeon's hands, surgical field, and medical instruments.

Directions for use and doses

Externally - applied to the skin using cotton swabs or napkins. They make compresses.

Side effects

Allergic reactions

Irritation and burns of the skin, mucous membranes and respiratory tract

May have a general resorptive effect toxic effect

CNS depression

Contraindications

Hypersensitivity to the drug

Drug interactions

When taken orally, it potentiates the effect of drugs that depress the central nervous system.

special instructions

For compresses (to avoid burns), ethanol should be diluted with water in a ratio of 1: 1 (70%, 90%).

Pregnancy and lactation

Use with caution

Childhood

Can be used in childhood for compresses in a dilution of 1: 4 (alcohol and water) - for a 90% solution, 1: 3 (alcohol and water) - for a 70% solution.

To sterilize surgical instruments, undiluted 95% alcohol is used.

Overdose

• Ethanol

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Pharmacotherapeutic group:

• Antimicrobial, antiparasitic and anthelmintic agents

Pharmacological properties:

Pharmacodynamics

Antiseptic. When applied externally it has antimicrobial effect. Active against gram-positive and gram-negative bacteria and viruses. Denatures proteins of microorganisms.

Antiseptic activity increases with increasing ethanol concentration.

To disinfect the skin, use a 70% solution, which penetrates into the deeper layers of the epidermis better than 95% and has a tanning effect on the skin and mucous membranes.

At systemic use has the ability to cause analgesia and general anesthesia. The most sensitive to ethanol are the cells of the central nervous system, especially the cells of the cerebral cortex, on which ethanol causes characteristic alcoholic excitation associated with a weakening of inhibition processes. Then there is also a weakening of excitation processes in the cortex, depression of the spinal and medulla oblongata with suppression of the activity of the respiratory center.

It is a solvent for a number of medicines, as well as an extractant for a number of substances contained in medicinal plant materials.

Pharmacokinetics

Ethanol is metabolized in the liver with the participation of the CYP2E1 isoenzyme, of which it is an inducer.

Indications for use:

Treatment of inflammatory skin diseases in the initial stage (boil, felon, mastitis); treatment of the surgeon’s hands (Furbringer, Alfred methods), surgical field (including in persons with hypersensitivity to other antiseptics, in children and during operations on areas with thin skin in adults - in the neck, face).

As a local irritant drug.

For the manufacture of dosage forms for external use, tinctures, extracts.

Conservation biological material.

Refers to diseases:

• Mastitis

Contraindications:

Hypersensitivity to ethanol.

Directions for use and dosage:

It is used depending on the indications and dosage form.

Side effect:

Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of application of the compress. When applied externally, it is partially absorbed through the skin and mucous membranes and may have a systemic toxic effect (CNS depression).

Interaction with other drugs:

When used simultaneously, it enhances the effect of drugs that have a depressant effect on the central nervous system, cardiovascular system, respiratory center.

When taken orally with drugs that have an inhibitory effect on the enzyme aldehyde dehydrogenase (which is involved in the metabolism of ethyl alcohol), the concentration of ethanol metabolite, acetaldehyde, increases, causing flushing, nausea, vomiting, general malaise, tachycardia, and decreased blood pressure.

Special instructions and precautions:

Should not be taken orally during drug treatment.

Use in childhood

When used externally, ethanol is partially absorbed through the skin and mucous membranes, which should be taken into account when used in children.

28.02.2012 3690

Ethanol. Description, instructions.

Treatment initial stages diseases: boil, felon, mastitis; treatment of the surgeon’s hands (Furbringer, Alfred methods), surgical field (including in persons with hypersensitivity to other antiseptics...

International name:
Ethanol

Description active substance(INN):
Ethanol

Dosage form:
solution for external use [alcohol], solution for external use and preparation of dosage forms

Pharmachologic effect:
Antimicrobial agent for local application has an antiseptic effect (denatures the proteins of microorganisms). Active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration. To disinfect the skin, use a 70% solution, which penetrates into the deeper layers of the epidermis better than 95% and has a tanning effect on the skin and mucous membranes. When administered systemically, it has the ability to cause analgesia and general anesthesia. It is a solvent for a number of drugs, as well as an extractant for a number of substances contained in medicinal plant materials.

Indications:
Treatment of the initial stages of diseases: boil, panaritium, mastitis; treatment of the surgeon's hands (Furbringer, Alfred methods), surgical field (including in persons with hypersensitivity to other antiseptics, in children and during operations on areas with thin skin in adults - neck, face). Conservation of biological material, production of dosage forms for external use, tinctures, extracts. As a locally irritating drug.

Contraindications:
Hypersensitivity.

Side effects:
Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of application of the compress. When applied externally, it is partially absorbed through the skin and mucous membranes and can have a resorptive general toxic effect (CNS depression).

Directions for use and dosage:
Externally, in the form of lotions. To treat the surgical field and preoperative disinfection of the surgeon’s hands, use a 70% solution; for compresses and rubdowns (to avoid burns), it is recommended to use a 40% solution. The 95% solution must be diluted to the required concentrations and used according to indications. As an irritating drug - in the form of rubdowns and compresses. Used internally in accordance with the instructions for medical use of dosage forms prepared on the basis of ethanol.

Special instructions:
When used externally, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when using it in children.

Ethanol

International nonproprietary name

Dosage form

Solution for external use 90%, 70%, 50 ml, 90 ml, 100 ml

Compound

1 liter of the drug contains 70% 90%

active substance- ethanol 96% 727 ml 937 ml

excipient- purified water up to 1 liter.

Description

Colorless, transparent, volatile, flammable liquid, with a characteristic alcoholic odor and pungent taste. Burns with a blue safe flame. Hygroscopic.

Pharmacotherapeutic group

Other antiseptics and disinfectants.

ATX code D08AX08

Pharmacological properties

The local and reflex action of ethanol consists of irritant, astringent and antiseptic effects. After exposure of the skin to concentrated solutions of ethyl alcohol (70% and 90%), an astringent effect occurs due to the denaturation of tissue proteins. The tanning effect of alcohol on the skin reduces its sensitivity and sweating, promoting analgesia and stopping itching.

The antiseptic effect is associated with the denaturation of cytoplasmic and membrane proteins of microbial cells. The bacterial flora is most sensitive to ethanol. The most optimal concentration for the bactericidal effect of the drug is 70%. At higher concentrations, the tanning (astringent) effect of alcohol on tissue structures complicates its diffusion, and the depth of the antiseptic effect decreases.

Indications for use

Treatment of hands, surgical instruments, surgical field

Prevention of bedsores in bedridden patients, wiping, compresses

Directions for use and doses

Externally for wiping: applied to the skin using cotton swabs and napkins.

They make compresses.

Side effects

Allergic reactions

Irritation and burns of the skin, mucous membranes and respiratory tract

When applied externally, it is partially absorbed through the skin and mucous membranes and can have a resorptive general toxic effect (CNS depression).

Contraindications

Hypersensitivity to ethanol

Drug interactions

When taken orally, it potentiates the effects of drugs that depress the central nervous system.

special instructions

For compresses (to avoid burns), ethanol should be diluted with water in a ratio of 1:1 (70%, 90%).

Undiluted 95% alcohol is used to sterilize surgical instruments.

Pregnancy and lactation

Use with caution.

Use in pediatrics

It can be used in children for compresses in a dilution of 1:4 (alcohol and water) - for a 90% solution, 1:3 (alcohol and water) - for a 70% solution.

When used externally, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when using it in children.

Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms

Does not affect

Overdose

When applied topically, an overdose is unlikely.

If taken orally, acute intoxication may develop.

Symptoms: tachycardia, metabolic acidosis, pulmonary edema, hypocalcemia, hypoglycemia, convulsions, depression of central functions nervous system. Death can occur as a result of paralysis of the respiratory center.

Treatment: the introduction of analeptics is inappropriate, artificial ventilation of the lungs is performed with the addition of oxygen, cardiac glycosides and ACE inhibitors are prescribed. If renal function is preserved and there are no signs of heart failure and pulmonary edema, forced diuresis can be used. Hypoglycemia and ketosis are corrected by administering glucose.

Release form and packaging

Trade name:

Medical antiseptic solution

International nonproprietary or generic name:

Dosage form:

concentrate for preparing a solution for external use

Compound:

Active substance:
ethanol (ethyl alcohol) 95% – 100.0 ml.

Description:

transparent, colorless, mobile liquid with a characteristic alcoholic odor.

Pharmacotherapeutic group:

antiseptic

ATX Code:

Pharmacological properties

Pharmacodynamics
An antimicrobial agent, when applied externally, has an antiseptic effect (denatures the proteins of microorganisms). Active against gram-positive and gram-negative bacteria and viruses. Antiseptic activity increases with increasing ethanol concentration.
To disinfect the skin, use a 70% solution, which penetrates into the deeper layers of the epidermis better than a 95% solution, which has a tanning effect on the skin and mucous membranes.
Pharmacokinetics
When applied externally, it is absorbed from the surface of the skin and mucous membranes into the systemic circulation. Metabolized in the liver with the participation of the CYP2E1 isoenzyme, of which it is an inducer.

Indications for use

Used as an antiseptic and disinfectant in the treatment of the initial stages of diseases (furuncle, panaritium, mastitis); when treating the surgeon's hands (Furbringer, Alfred methods), the surgical field (including in persons with hypersensitivity to other antiseptics, in children and during operations on areas with thin skin in adults - neck, face).

Contraindications

Hypersensitivity.

Carefully

Pregnancy, period breastfeeding, childhood.

Use during pregnancy and breastfeeding

No special studies have been conducted on the use of the drug during pregnancy and breastfeeding. During pregnancy and breastfeeding, it is used only if the expected benefit to the mother outweighs the potential risk to the fetus and child.

Directions for use and doses

Externally, in the form of lotions, compresses, rubdowns.
To treat the surgical field and preoperative disinfection of the surgeon’s hands, use a 70% solution; for compresses and rubdowns (to avoid burns), it is recommended to use a 40% solution.
The 95% solution must be diluted to the required concentrations and used according to indications.

Side effect

Allergic reactions, skin burns, hyperemia and soreness of the skin at the site of application of the compress.
When used externally, it is partially absorbed through the skin and can have a resorptive general toxic effect (suppression of the central nervous system).

Overdose

Causes characteristic alcoholic excitation; in large doses, it inhibits the functions of the central nervous system.

Interaction with other drugs

When used simultaneously with preparations for external use that contain organic compounds, it can cause denaturation of protein components.

special instructions

When used externally, ethanol is partially absorbed through the skin and mucous membranes, which must be taken into account when using it in children, pregnant women and during lactation.
Do not use near open flames.

Impact on the ability to drive vehicles and machinery

The drug, used as a solution for external use, does not affect the ability to drive or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions. With long-term use in large doses, the drug may be absorbed into the systemic bloodstream, which must be taken into account when controlling transport and mechanisms. Release form

Concentrate for preparing a solution for external use 95%.
100 ml in orange glass bottles, sealed with perforated aluminum caps. A self-adhesive label is attached to each bottle. Each bottle, along with instructions for use, is placed in a cardboard pack.
40 bottles with an equal number of instructions for use are placed in a corrugated cardboard box (for hospitals).
5.0, 10.0 and 21.5 liters in polyethylene canisters low pressure. Each canister is supplied with instructions for use (for hospitals).

Best before date

5 years. Do not use after the expiration date.

Storage conditions

At a temperature not exceeding 25 ° C, in a well-closed container, away from fire.
Keep out of the reach of children.

Vacation conditions

Dispensed by prescription.

Marketing authorization holder / Organization receiving consumer complaints

Alliance LLC, 192019, St. Petersburg, st. 2nd Luch, 13, room. 13

Manufacturer

LLC "Armavir Interdistrict Pharmacy Base".

Addresses of production sites:
1) 352900, Krasnodar region, Armavir, st. Tonnelnaya, 24
2) 174360, Novgorod region, Okulovsky municipal district, urban settlement Uglovskoye, village. Berezovka, p. 75 A.