Chondrolone injections instructions for use contraindications. Chondrolone: ​​features of therapeutic action, composition of the drug, absorption and excretion from the body. Alflutop or Chondrolon – which is better?

The modern natural drug Chondrolone is designed specifically to prevent further inflammatory process. It effectively protects cartilage and promotes its rapid regeneration.

Problems of the disease

Approximately 15% of the world's population complain of recurring pain in the back, radiating to the arm, leg or neck with even more acute pain. In this case, some stiffness of movements occurs. Such symptoms mean that the intervertebral discs are inflamed and their natural functions are impaired. Due to the pathological process, thinning of the cartilage of the joints and intervertebral discs occurs, as a result of which the bone tissue of the vertebrae is deformed. Then, due to inflammation, muscle spasm and severe pain are added. After the initial symptoms occur, intervertebral hernias form as a complication of the disease. Hernias have a compressive effect on the spinal cord and nerve endings, and in this case many systems in the human body suffer.

All these manifestations are signs of osteochondrosis.

Mechanism of action

Proteoglycan chondroitin sulfate is a special protein-carbohydrate compound, which is the main substance of the drug Chondrolone. This unique component is the main component of the intercellular substance of cartilage tissue; it is what makes it strong and elastic. Moisture is retained in cartilage and joints by the molecules of this substance and, thanks to this, various mechanical loads are softened.

With a disease such as osteochondrosis, cartilage cells (chondrocytes) no longer receive the required amount of nutrients. Because of this, their functionality and the production of those same proteoglycans sharply decrease. The result of this is dehydration of the cartilage, reducing its density and shock-absorbing qualities.

To maintain cartilage cells in normal condition, their nutrition and production of intercellular substance, chondroitin sulfate is administered. Therefore, Chondrolone has a beneficial effect on the condition of bone tissue and effectively regenerates it after destructive inflammation.

The drug promotes the production of synovium (the fluid that fills the joints) and improves its quality. This ensures the best lubrication of the joints and their unhindered sliding, without traumatic friction against each other. Synovial fluid is very important for the joint, but its excess amount, which causes inflammation, overstretches the joint capsule and leads to a decrease in its motor activity and pain.

Chondrolone is a drug created on the basis of chondroitinsulfuric acid; it belongs to the group of second-generation chondroprotectors. The use of the drug prevents the development of joint degeneration, which leads to partial or complete destruction of the joint. Chondrolone also restores metabolic processes in the body, helps strengthen the skeletal system, and stimulates collagen synthesis. Analgesic and anti-inflammatory effects are also included in the therapeutic effect of Chondrolone.

Important! The drug is well absorbed into the blood and already half an hour after intramuscular administration of the drug, a high content of the substance is detected in it.

Indications for use

The drug Chondrolone has received good reviews when used as part of complex therapy. As an independent medicine, it is indicated for diseases such as:

• osteochondrosis;
• Spinal spondylosis is a condition in which the vertebrae are deformed due to excessive growth of bone tissue in the form of sharp growths;
• arthritis and arthrosis of the joints of the hands and feet;
• post-traumatic or postoperative rehabilitation period;
• osteoarthritis of the spine - thinning or degeneration of cartilage and bones located nearby;
• chondrocalcinosis - accumulation of calcium salts on the joints; - secondary damage to the joints due to the presence of their underlying disease;
• used to restore calcium and phosphorus metabolism in the body (auxiliary therapy);
• the drug is prescribed to professional athletes with increased stress on the joints;
• for bone fractures has a good restorative effect;
• It is possible to use Chondrolone for dental purposes in case of periodontopathy.

Chondrolon injections

Before prescribing the drug, the attending physician examines the patient. Based on the results, an individual treatment regimen with Chondrolone is developed.

In just a few weeks, significant changes for the better should appear in the patient’s condition. If you combine injections of Chondrolone (or its analogues) with moderate physical activity, also selected for a specific patient, then positive results can be achieved even faster. Physical activity stimulates blood flow, which is why medicinal components have better access to the lesions.

The average duration of treatment is approximately 25-35 injections - it depends on the individual characteristics of the patient. The recommended number of injections is 35, the minimum is 25. The next course of injections can be prescribed no earlier than 6 months after the previous one.

Before use, the ampoule with the substance must be opened using a special knife (it comes in the package with the drug). 1 ml of injection water is introduced into the open ampoule and it is all mixed until a homogeneous mixture is obtained. After this, the solution is considered ready and can be drawn into a syringe.

The administration must be extremely careful - the drug should not be allowed to enter the blood vessels. Before injection, the syringe piston is pulled back strongly - this is done in order to prevent the substance from entering the vessels. If suddenly a bloody admixture is detected in the syringe, this means that you should try to inject it into another place, since a blood vessel has been touched. If you do not adhere to this rule, then significant hematomas remain at the injection site.

Important! It is also necessary to choose different injection sites, otherwise painful lumps will appear.

Chondrolone is administered intramuscularly, after one day, the dosage per injection is 100 mg. If the attending physician has recorded good tolerance of such treatment by the patient, then the dose is increased to 200 ml (2 ampoules also once every other day). But increasing the dosage is possible no earlier than after 4 injections.

The maximum level of Chondrolone in the blood is recorded an hour after intramuscular administration. It also tends to accumulate in joint fluid. After a day, the drug is excreted from the body along with urine.

Already after the first course of treatment with Chondrolone, a persistent improvement in the patient’s well-being is noticed. After the second course of injections, the effect is consolidated and maintained for a long period.

The effectiveness of such treatment can be judged by the following changes:

• the process of calcium release from bones and joints slows down, this allows them to remain dense and elastic;
• calcium-phosphorus metabolism in joints improves: restoration processes in tissues are accelerated and their destruction noticeably slows down;
• the work of enzymes slows down or is suppressed, causing damage to cartilage tissue;
• the formation of polysaccharide chains is stimulated.

Side effects

The drug Chondrolone belongs to the group of highly purified natural drugs, which significantly reduces the risk of side effects. But, as with any other drug, unwanted reactions are still possible. The instructions for use indicate the following side effects:

• allergies in the form of skin itching and urticaria;
• release of blood from tissues or lumens of blood vessels (hemorrhage);
• slight increase in body temperature;
• redness of areas of the skin.

If any of the above symptoms occur, the drug is immediately discontinued or replaced with a similar drug.

Contraindications

Chondrolone should not be used if the patient has the following diseases:

• thrombophlebitis and other conditions in which there is a possible risk of thrombosis;
• tendency to various types of bleeding, impaired blood clotting;
• individual intolerance to the components of the drug is a direct contraindication to such treatment;
• children under 16 years of age - the drug has not been tested in pediatrics;
• the period of bearing a child is considered a contraindication, since there is no information in medicine about the safety of using Chondrolone during such a period.

Interaction with other drugs

Chondrolone compares favorably with analogues in its good compatibility with other drugs. However, it can to some extent enhance the effect of drugs aimed at reducing blood clotting - anticoagulants and antiplatelet agents. The separate use of such medications, and especially the combined use, should be carried out under the constant supervision of the attending physician.

It should be remembered that drugs in the antiplatelet group include the familiar aspirin. Therefore, when treating with Chondrolone, you should stop using aspirin.

If you still notice initial signs of poor blood clotting (quick appearance of bruises even from the most minimal mechanical damage), you should immediately consult a doctor.

Important! To reliably find out about the compatibility of Chondrolone with any other drug, conducting a special blood clotting test will help.

Release form and composition

Chondrolone is a white powder. It is produced in transparent ampoules, which are packaged in boxes of 5-10-20 pieces. The drug contains only one component - chondroitin sulfate. It is obtained from the cartilage and ligament tissue of cattle. After intensive processing and purification from impurities of proteins and other elements, it is considered ready for use.

There are no other forms of release of the drug.

Price

The cost of Chondrolon cannot be called low. One ampoule of the medicine costs 140 rubles. A pack of ten ampoules will cost 1,350 rubles. If a course of treatment is required, designed for 25 injections, then you will have to spend about four thousand rubles on this.

The medicine is dispensed in pharmacies strictly according to a doctor's prescription.

Analogs

The range of medications belonging to the same group as Chondrolone is quite rich.

They differ in manufacturer and cost, but their composition is approximately the same.

1. Chondroxide, unlike Chondrolone, is available exclusively in the form of ointments, creams and tablets and is suitable for external and oral use.
2. Alflutop contains chondroitin sulfate; the auxiliary components of the drug are trace elements, hyaluronic acid, marine fish extract, and amino acids. This medicine is used in the form of injections. However, its cost is slightly higher - this analogue will cost the patient 1700-2330 rubles for one pack of ten ampoules. The manufacturer is the Romanian company Biotechnos.
3. Mucosat is a drug produced in Belarus. It is produced in the form of a powder for injection. Its composition is identical to that of Chondrolone.
4. Artradol is a drug produced by the Russian pharmaceutical company Inkapharm. The composition, release form and use are all the same as in the case of Chondrolone. The only difference is the cost - 650-900 rubles per package.
5. Khonsurid is also a product of the Russian pharmaceutical market, in this case it is the Samson-med company. Its distinctive feature is that it is created from the trachea of ​​cattle. However, it also contains only natural ingredients.

Despite their almost identical composition, the therapeutic effect of each of these drugs is slightly different. Some of them are indicated only for professional injuries of athletes as part of complex therapy.

Back pain, stiffness of movement, “shooting” in the neck, arm, leg - this is just a small list of symptoms of osteochondrosis. The disease affects the intervertebral joints, which leads to dysfunction and inflammation. Articular cartilage and intervertebral discs become thinner, and mechanical damage to the bone tissue of the vertebrae occurs.

Inflammation leads to the formation of pain and muscle spasms, which aggravates the situation even further. Over time, osteochondrosis is complicated by intervertebral hernias, which compress the nerve roots and spinal cord, disrupting the functioning of many organ systems.

The natural drug Chondrolone can stop the pathological process - it protects cartilage tissue and stimulates its restoration.

The mechanism of action of Chondrolone in injections

The active substance of Chondrolone is proteoglycan (protein-carbohydrate compound) chondroitin sulfate. It is the main component of the intercellular substance of cartilage tissue and provides its elastic properties.

Proteoglycan molecules retain moisture inside the cartilage of the intervertebral joints, due to which they absorb mechanical pressure, shocks, and shocks.

With osteochondrosis, cartilage tissue cells (chondrocytes) do not receive enough nutrients and their synthetic function decreases. They produce proteoglycans in smaller quantities, as a result of which the cartilage loses water, becomes thinner and cannot spring back when compressed.

The introduction of chondroitin sulfate in the form of drugs improves the nutrition of chondrocytes and stimulates the synthesis of intercellular substances. Chondrolone has a beneficial effect on metabolism in bone tissue, which leads to its recovery after inflammatory damage.

It normalizes the composition and quantity of synovial fluid - it is necessary in small quantities to lubricate the articular surfaces and facilitate their mutual sliding. With inflammation, its volume increases, which leads to overstretching of the joint capsule, pain and decreased mobility.

Description and composition

Chondrolone is a white powder, packaged in 0.1 g ampoules of transparent glass. Before intramuscular administration, the powder is dissolved in sterile water for injection: it can be included with the drug or purchased separately at the pharmacy. Ampoules are placed in cardboard boxes of 5-40 pieces each.

The powder is 100% chondroitin sulfate, which is extracted from the cartilage and ligaments of cattle. The drug is purified from protein and other impurities, due to which it is well tolerated by most patients and does not cause allergic reactions.

Indications for use

Chondrolone is prescribed as part of complex treatment and for the prevention of exacerbations of diseases such as:

• osteochondrosis;
• arthrosis and arthritis of the joints of the limbs;
• rehabilitation period after joint injuries or operations on them.

Contraindications

The effect of Chondrolone has not been clinically studied in pregnant women and children, so the drug is contraindicated in these groups of patients. However, the ban is not absolute: the decision on use is made by the attending physician, based on the patient’s condition and the severity of his illness.

Chondrolone affects blood clotting, so it is not used in patients with a tendency to blood clots or bleeding. An absolute contraindication to the use of Chondrolone is intolerance to the drug and associated allergic reactions.

Instructions for using injections

The Chondrolone ampoule is opened with a special knife - it comes complete with the drug. Then 1 ml of sterile water for injection is injected into it with a syringe and gently mixed until the powder is completely dissolved. The resulting solution is taken into a syringe - it is ready for use.

Chondrolone is administered intramuscularly, avoiding entry into blood vessels. To do this, before starting to administer the drug, pull the syringe plunger towards you: if blood gets into the solution, remove the needle from the muscle and insert it into another point. Otherwise, the risk of hematoma formation at the injection site increases.

Therapy begins with 100 mg of Chondrolone per day, if well tolerated, it is increased to 200 mg (not earlier than after the 4th injection). The course of treatment is prescribed by the doctor individually, on average it is 25-35 injections every other day.

The injection sites should be alternated to avoid the formation of painful lumps. Repeated courses of treatment are carried out after six months.

Side effects

The drug Chondrolone is natural and highly purified, so it rarely causes side effects. Among them the following are possible:

• small subcutaneous hemorrhages at the injection sites;
• allergic reactions such as urticaria, itching, swelling on the face.

Interaction

Chondrolone can enhance the effect of drugs to reduce blood clotting (anticoagulants, antiplatelet agents), which can lead to bleeding. Their combined use is possible only under the supervision of a doctor and with laboratory control (coagulogram analysis).

The most common antiplatelet agent in our country is acetylsalicylic acid or simply aspirin. If during the course of treatment with a chondroprotector it becomes necessary to take it, you should be aware of the possible interaction. At the first signs of deterioration in blood clotting (the appearance of bruises with minor exposure), you should consult a doctor.

Medicine price

The average cost of Chondrolon is:

• 140 rubles for 1 ampoule of 100 mg;
• 1350 for 10 ampoules of 100 mg.

• Latin name: Chondrolon
• ATX code: M01AX25
• Active substance: Chondroitin sulfate (Chondroitini sulfas)
• Manufacturer: Immunopreparat, Russia

Compound

Contraindications

• inclination towards;
• hypersensitivity to the drug;
• period lactation .

Side effects

Terms of sale

On prescription.

Storage conditions

Stored at a temperature not exceeding 20°C.

Best before date

Chondrolon analogs

The main analogues of Chondrolone: Chondrogard , .

Alflutop and Chondrolone are often compared.

Alflutop or Chondrolon – which is better?

The first drug is made from a concentrate of small sea fish, it contains chondroitin sulfate , but what its dose in the drug is unknown. Chondrolone contains a fairly serious dose chondroitin , which has shown an effect in the treatment of lesions of the spine and joints. However, even on Alflutop there are many good reviews, especially in treatment deforming osteoarthritis large joints - knee, hip.

If you analyze all the reviews, you can see that most often Chondrolone shows an effect when, and Alflutop – with lesions of peripheral joints.

There are also tablets - analogues: Chondroitin , Hondarollar , Structum

The price of analogue injections starts from 264 rubles. (per package Mucosata ) up to 1645 rub. - it costs so much Alflutop .

Synonyms

Artradol , Mucosat , Chondrogard , .

For children

Not used due to lack of data on efficacy and safety.

During pregnancy and lactation

Contraindicated.

Reviews about Chondrolone

Reviews about Chondrolone injections, namely its effectiveness, vary. It helps some patients very well during repeated courses of treatment. As a rule, these are not advanced stages of the disease. They also indicate that at least 40 ampoules are needed for one course, but then you can forget about joint pain for 1.5 - 2 years. There are reviews from patients about the insufficient effect for severe joint damage. In this case, it is best to use the drug as part of complex therapy, for example, with physiotherapy . Disadvantages include the significant pain of injections and the high cost of the full course of treatment.

Reviews from doctors indicate that the use of injections is widespread in patients with osteochondrosis of the spine . Doctors note a good effect, but this also depends on the severity of the lesion.

Chondrolon price, where to buy

The price of Chondrolon varies depending on the region from 699 rubles. up to 920 rub. for 10 ampoules. The price of Chondrolon injections in Moscow is 671 rubles.

In Ukrainian pharmacies the cost of the drug ranges from 475 to 556 UAH. per package.

• Online pharmacies in Russia Russia
• Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

Chondrolone lyof intramuscularly 100 mg n10FSUE Microgen NPO FSUE

Ant honey gel-balm for legs with chondrolone 70g Spetsmaz LLC

"Chondrolon" improves metabolism in hyaline cartilage, reduces pain and increases joint mobility. The effect of the drug appears two to three weeks after the injection and lasts for a long time. The highest concentration in the blood is achieved 1 hour after the injection. The period of elimination from the body is one day.

The drug consists of chondroitin sulfate A and C sodium salts, which are made from cattle cartilage.

Indications for use

The drug is used to treat diseases of the joints and spine:

• Reactive arthritis (you can read more about it)
• Arthrosis
• Osteochondrosis
• Osteoarthrosis.

The drug is also prescribed to people who play sports professionally and have increased stress on their joints. Has a positive effect on bone tissue regeneration after a fracture. Additionally used by dentists in the treatment of periodontopathy.

Forms of release and method of application

Average price from 374 to 564 rubles.

"Chondrolon" cream

The main active ingredients are chondroitin sulfate and glucosamine sulfate. “Chondrolone gel” is available in tubes of 30 or 75 g. The effect of the gel is also aimed at accelerating the restoration of cartilage in the joints, reducing pain, and increasing joint mobility.

The cream is applied 2 or 3 times a day to the skin over the lesion. It must be rubbed into the skin for several minutes (sometimes 2-3 minutes is enough) until completely absorbed.

"Chondrolon" ampoules

"Chondrolone" is available in ampoules containing 100 mg of lyophilisate (single dose for administration). It has the appearance of a white, odorless, loose powder. Ampoules are packaged in cardboard packages of 5, 10, 20 pieces. They come with a solution for diluting the powder and a knife for ampoules.

The average price is from 1100 to 1400 rubles.

The drug is injected into muscle tissue. To do this, 1 ml of the solution is injected into an ampoule with powder and shaken thoroughly so that it dissolves better. If you need to administer a double dose, “Chondrolone” is drawn from two ampoules with one syringe. Injections are given every other day. If there are no side effects, the fifth injection is given in double dose. The treatment course lasts two months - that's about 30 injections. Repeated treatment can be taken only as prescribed by a doctor.

Contraindications

• Increased bleeding
• Thrombophlebitis
• Individual intolerance of the body.

The drug is not prescribed to children due to the lack of data on the safety of use.

During pregnancy and breastfeeding

Chondrolone is not prescribed for pregnant and lactating women.

Precautionary measures

In case of allergic manifestations or bruises at the injection site, it is better to immediately interrupt the treatment course.

Interaction with other drugs

"Chondrolone" enhances the effects of certain substances. Therefore, the drug cannot be used simultaneously with:

• Fibrinolytics
• Indirect coagulants
• Antiplatelet agents.

Side effects

The following symptoms may occur:

• Fever
• Redness
• Bruise at the injection site
• Skin rashes.

In these cases, it is necessary to stop injections.

Conditions and shelf life

It is better to store Chondrolon at a temperature not exceeding 20°C in a dry, dark place. The drug is suitable for use for three years from the date of manufacture.

Analogs

Although there are other medications with the same active ingredient, they differ in their characteristics.

CJSC PharmFirma Sotex, Russia
Price from 754 to 1300 rub.

The active ingredient is chondroitin sulfate. "Chondrogard" looks like a transparent solution that has no color, or is slightly yellowish, and smells of benzyl alcohol.

pros

• "Chondroguard" is available in ampoules not only of 100 mg, but also of 200 mg, so it is better to use it when a double dose is administered
• Accelerates bone healing after a fracture

Minuses

• The drug has a longer elimination period from the body, amounting to two days.
• The use of Chondrogard can cause skin itching, urticaria, and erythema.

Biotehnos S.A., Romania
Price from 1969 to 3297 rub.

Chondroitin sulfate is the main active agent. "Alflutop" has the form of a solution containing an extract from small sea fish with the addition of phenol

pros

• In a calm state, Alflutop reduces pain by at least 90%
• For some diseases, Alflutop reduces pain while climbing stairs and removes swelling
• "Alflutop" is available for intra-articular injections

Minuses

• Pain in muscle tissue that lasts a short time
• Increased pain in case of intra-articular injection
• In rare cases, the administration of Alflutop causes anaphylactic shock.

« »

Biok, Russia
Price from 697 to 729 rub.

The active substance is chondroitin sulfate. "Artradol" looks like a dry mass of white or slightly yellowish color.

pros

• Restores cartilage tissue in joints
• Articular fluid is better produced, which increases the motor ability of the joint

Minuses

• Possible bleeding at the injection site
• Dermatitis and redness.

Chondrolone is a drug that activates metabolic processes in cartilage. Stops the destruction of joints, accelerates the synthesis of glycosaminoglycans, which are the basis of cartilage.

Taking Chondrolone helps eliminate symptoms such as pain and decreased mobility (due to the secretion of synovial fluid). Progress becomes noticeable 14–20 days after the start of the course, but since the action of Chondrolone is based on a cumulative effect, the main changes will be observed after completing the course.

In this article we will look at why doctors prescribe Chondrolone, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Chondrolon can be read in the comments.

Composition and release form

In medical networks, the drug Chondrolone is presented in the form of a lyophilisate (dry extraction of the active substance), packaged in ampoules.

One ampoule contains one dose of medicine with an extract from the cartilage of large horned domestic animals in an amount of 100 mg. That is, 100 mg of chondroitin sulfate is the content of 1 ampoule.

One pack contains 10 ampoules, supplied complete with a knife and solvent for preparing injections.

What is Chondrolone used for?

The drug is used to treat diseases of the joints and spine:

1. Reactive arthritis;
2. Arthrosis;
3. Osteochondrosis;
4. Osteoarthrosis.

The drug is also prescribed to people who play sports professionally and have increased stress on their joints. Has a positive effect on bone tissue regeneration after a fracture. Additionally used by dentists in the treatment of periodontopathy.

Mechanism of action

The basis of Chondrolone is the substance chondroitin sulfate. It is a mucopolysaccharide with a high molecular weight. Main directions of impact:

• inhibition of the destruction process;
• stimulation of the synthesis of own protective glycosaminoglycans;
• restoration of cartilaginous surfaces and tissue of the joint capsule;
• suppression of enzyme activity aimed at tissue destruction;
• increasing the production of intra-articular fluid and normalizing its composition;
• restoration of impaired calcium and phosphorus metabolism in bone and cartilage tissues;
• reduction of thrombus formation in small vessels around the joint capsule.

Considering all the capabilities of the drug, it is included in the extensive group of chondroprotectors (medicines that protect and restore joints). The drugs are recommended by the European League Against Rheumatism as the basis for the treatment of joint diseases.

Instructions for use

The Chondrolone ampoule is opened with a special knife - it comes complete with the drug. Then 1 ml of sterile water for injection is injected into it with a syringe and gently mixed until the powder is completely dissolved. The resulting solution is taken into a syringe - it is ready for use.

Chondrolone is administered intramuscularly, avoiding entry into blood vessels. To do this, before starting to administer the drug, pull the syringe plunger towards you: if blood gets into the solution, remove the needle from the muscle and insert it into another point. Otherwise, the risk of hematoma formation at the injection site increases.

According to the instructions for use, Chondrolone is administered intramuscularly at 100 mg (1 ampoule) every other day. Before use, the contents of the ampoule are dissolved in 1 ml of water for injection. If well tolerated, the dose is increased to 200 mg (2 ampoules), starting with the fourth injection. The course of treatment is 25-35 injections. Repeated courses – after 6 months.

The duration of repeated courses of treatment is determined by the doctor. To achieve a stable clinical effect, at least 25 injections of chondrolone are required, and the effect persists long after the end of the repeated course of treatment.

Contraindications

Chondrolone is contraindicated when the patient has the following conditions or diseases:

1. The presence of thrombophlebitis of any localization;
2. Allergy to the drug and its components;
3. Tendency to bleeding;
4. During pregnancy;
5. Breastfeeding period;
6. Kidney failure.

Side effects

As a result of using the product according to the instructions for use, side effects may occur:

• elevated temperature;
• allergic rash, irritation;
• local redness of the skin;
• hemorrhages in the area of ​​application of the product.

The appearance of one or more of the listed symptoms may be an indication for discontinuation of Chondrolone injections. You should stop taking the drug or ask your doctor to replace it with one of its analogues.

Pregnancy and lactation

Contraindicated during pregnancy and lactation.

Analogs

The most effective and similar in principle to the drug Chondrolone are chondroprotectors, which also contain the active ingredient chondroitin sulfate.

1. Mucosat is a Belarusian remedy. Available in the form of a ready-made solution for intramuscular injection, which is most convenient for use. The composition is similar to chondrolone. Each ampoule contains 100 mg of active ingredient. Price - from 300 rubles.
2. Alflutop is one of the popular expensive analogues produced by the Romanian company Biotechnos. The cost in Russia averages 1700-2300 rubles for 10 ampoules. In addition to chondroitin sulfate, Alflutop contains marine fish extracts, amino acids, trace elements, and hyaluronic acid. Can be used for intra-articular injections.
3. Artradol is produced by the Russian company Incampharm. It has a similar release form, composition and application regimen. The price is a little cheaper - 650-900 rubles.
4. Chondroxide is produced by the pharmacological companies Nizhpharm and Makiz Pharma. Presented in the form of ointments, creams and tablets, each of which contains 250 mg of active ingredient. The price per package is 250-500 rubles.
5. Khonsurid - produced by the Russian company Samson-Med. Made from hyaline cartilage (trachea) of cattle. Contains only natural ingredients.

Attention: the use of analogues must be agreed with the attending physician.